CY2471B1 - Fungal protease. - Google Patents

Fungal protease.

Info

Publication number
CY2471B1
CY2471B1 CY0400062A CY0400062A CY2471B1 CY 2471 B1 CY2471 B1 CY 2471B1 CY 0400062 A CY0400062 A CY 0400062A CY 0400062 A CY0400062 A CY 0400062A CY 2471 B1 CY2471 B1 CY 2471B1
Authority
CY
Cyprus
Prior art keywords
aspergillus
protease
preparation
mutant strain
aspartic
Prior art date
Application number
CY0400062A
Other languages
English (en)
Inventor
Frank Buxton
Gabor Jarai
Jacob Visser
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CY2471B1 publication Critical patent/CY2471B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CY0400062A 1993-11-03 2004-08-10 Fungal protease. CY2471B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93810764 1993-11-03

Publications (1)

Publication Number Publication Date
CY2471B1 true CY2471B1 (en) 2005-06-03

Family

ID=8215057

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0400062A CY2471B1 (en) 1993-11-03 2004-08-10 Fungal protease.

Country Status (18)

Country Link
US (2) US5674728A (pt)
EP (1) EP0655497B1 (pt)
JP (1) JP3727678B2 (pt)
KR (1) KR100378507B1 (pt)
AT (1) ATE235556T1 (pt)
AU (1) AU688379B2 (pt)
CA (1) CA2134863C (pt)
CY (1) CY2471B1 (pt)
DE (1) DE69432336T2 (pt)
DK (1) DK0655497T3 (pt)
ES (1) ES2196019T3 (pt)
FI (1) FI119060B (pt)
HU (1) HU220360B (pt)
IL (2) IL168245A (pt)
NO (1) NO315330B1 (pt)
NZ (1) NZ264839A (pt)
PT (1) PT655497E (pt)
ZA (1) ZA948619B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997020921A1 (en) * 1995-12-07 1997-06-12 Novo Nordisk A/S Selective inactivation of enzyme activities
JP2000501620A (ja) * 1995-12-15 2000-02-15 ノボ ノルディスク アクティーゼルスカブ ａｒｅＡ，ｐｅｐＣ及び／又はｐｅｐＥ遺伝子が不活性化されている菌類
EP0907744A1 (en) * 1996-06-05 1999-04-14 Gist-Brocades B.V. Fungal metallo protease genes
DK0956338T3 (da) * 1996-09-19 2006-05-08 Novozymes As Værtsceller og fremgangsmåder til produktion af proteiner
ATE517988T1 (de) * 2001-02-23 2011-08-15 Dsm Ip Assets Bv Neue gene, die neue proteolytische enzyme codieren
AU2006202723B2 (en) * 2001-02-23 2008-06-26 Dsm Ip Assets B.V. Novel genes encoding novel proteolytic enzymes
EP2123749A3 (en) * 2001-02-23 2010-02-24 DSM IP Assets B.V. Novel genes encoding novel proteolytic enzymes
US20090253173A1 (en) * 2008-04-08 2009-10-08 Danisco Us Inc., Genencor Division Filamentous fungi with inactivated protease genes for altered protein production
FI121712B (fi) * 2009-04-30 2011-03-15 Ab Enzymes Oy Uusi sieniperäinen proteaasi ja sen käyttö
RU2645252C2 (ru) 2012-01-05 2018-02-19 Глюкос Финланд Ой Клетка нитчатых грибов с дефицитом протеаз и способы ее применения
WO2013174927A1 (en) 2012-05-23 2013-11-28 Novartis International Pharmaceutical Limited Production of fucosylated glycoproteins
RU2016104064A (ru) 2013-07-10 2017-08-15 Новартис Аг Клетки мицелиальных грибов с множественной недостаточностью протеаз и способы их использования
CN108064266A (zh) 2014-07-21 2018-05-22 格利科斯芬兰公司 在丝状真菌中具有哺乳动物样n-聚糖的糖蛋白的制备
CN106222096B (zh) * 2016-08-18 2018-02-23 滨州学院 一株塔宾曲霉菌ct1及其在盐碱地解磷方面的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8415186D0 (en) * 1984-06-14 1984-07-18 Ciba Geigy Ag Polypeptides
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
GB8702475D0 (en) * 1987-02-04 1987-03-11 Ciba Geigy Ag Expression system
AU1572588A (en) * 1987-03-12 1988-10-10 Genex Corp. Production of bioadhesive precursor protein analogs by genetically-engineered organisms
US4871824A (en) * 1987-03-13 1989-10-03 Minnesota Mining And Manufacturing Company Variably crosslinked polymeric supports
US5252726A (en) * 1987-09-04 1993-10-12 Novo Nordisk A/S Promoters for use in aspergillus
CA1333777C (en) * 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
EP0353188B2 (en) * 1988-07-28 2002-03-06 Novartis AG Novel expression system
EP0421919A3 (en) * 1989-09-02 1992-04-15 Ciba-Geigy Ag Polygalacturonase encoding fungal expression system
NZ236434A (en) * 1990-01-29 1992-08-26 Ciba Geigy Ag Dna molecules comprising the a niger pyruvate kinase transcription promoter, vectors containing it and their use in transforming host cells
ES2177528T3 (es) * 1991-04-01 2002-12-16 Merck & Co Inc Genes que influyen en la actividad proteolitica de pichia y usoso de los mismos.
DK47493D0 (da) * 1993-04-27 1993-04-27 Novo Nordisk As Fremgangsmaade til fremstilling af ost

Also Published As

Publication number Publication date
IL111482A0 (en) 1995-01-24
KR950014309A (ko) 1995-06-15
CA2134863A1 (en) 1995-05-04
DE69432336T2 (de) 2003-12-04
NO944181L (no) 1995-05-04
IL168245A (en) 2009-12-24
KR100378507B1 (ko) 2003-09-19
DE69432336D1 (de) 2003-04-30
AU7751494A (en) 1995-05-18
PT655497E (pt) 2003-07-31
US5756338A (en) 1998-05-26
NO944181D0 (no) 1994-11-02
NO315330B1 (no) 2003-08-18
IL111482A (en) 2005-08-31
HUT69954A (en) 1995-09-28
FI945163A (fi) 1995-05-04
EP0655497B1 (en) 2003-03-26
ES2196019T3 (es) 2003-12-16
DK0655497T3 (da) 2003-07-21
FI119060B (fi) 2008-07-15
ATE235556T1 (de) 2003-04-15
JP3727678B2 (ja) 2005-12-14
EP0655497A2 (en) 1995-05-31
US5674728A (en) 1997-10-07
FI945163A0 (fi) 1994-11-02
ZA948619B (en) 1995-06-27
EP0655497A3 (en) 1997-05-07
CA2134863C (en) 2008-12-30
JPH07213286A (ja) 1995-08-15
NZ264839A (en) 1996-03-26
HU9403136D0 (en) 1994-12-28
HU220360B (hu) 2001-12-28
AU688379B2 (en) 1998-03-12

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