CY2290B1 - Spirooxathiolane-quinuclidine derivative for the treatment of xerostomia - Google Patents

Spirooxathiolane-quinuclidine derivative for the treatment of xerostomia

Info

Publication number
CY2290B1
CY2290B1 CY0200048A CY0200048A CY2290B1 CY 2290 B1 CY2290 B1 CY 2290B1 CY 0200048 A CY0200048 A CY 0200048A CY 0200048 A CY0200048 A CY 0200048A CY 2290 B1 CY2290 B1 CY 2290B1
Authority
CY
Cyprus
Prior art keywords
xerostomia
salivary gland
spirooxathiolane
alkyl
treatment
Prior art date
Application number
CY0200048A
Other languages
English (en)
Inventor
Harumi Handa
Yasuyoshi Takeshita
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of CY2290B1 publication Critical patent/CY2290B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
CY0200048A 1994-06-27 2002-07-31 Spirooxathiolane-quinuclidine derivative for the treatment of xerostomia CY2290B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6168982A JP2852608B2 (ja) 1994-06-27 1994-06-27 口腔乾燥症治療剤

Publications (1)

Publication Number Publication Date
CY2290B1 true CY2290B1 (en) 2003-07-04

Family

ID=15878165

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0200048A CY2290B1 (en) 1994-06-27 2002-07-31 Spirooxathiolane-quinuclidine derivative for the treatment of xerostomia

Country Status (15)

Country Link
US (1) US5580880A (de)
EP (1) EP0689836B1 (de)
JP (1) JP2852608B2 (de)
KR (1) KR100322042B1 (de)
AT (1) ATE205085T1 (de)
AU (1) AU707236B2 (de)
CA (1) CA2152420A1 (de)
CY (1) CY2290B1 (de)
DE (1) DE69522511T2 (de)
DK (1) DK0689836T3 (de)
ES (1) ES2163474T3 (de)
IL (1) IL114256A (de)
NO (1) NO309454B1 (de)
TW (1) TW401298B (de)
ZA (1) ZA955317B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618341D0 (en) * 1996-09-03 1996-10-16 Scotia Holdings Plc Method of treatment
JP4447685B2 (ja) * 1999-01-14 2010-04-07 第一三共株式会社 皮膚乾燥症治療剤
JP4909809B2 (ja) * 1999-03-24 2012-04-04 生化学工業株式会社 人工唾液
WO2006013914A1 (ja) * 2004-08-06 2006-02-09 Daiichi Pharmaceutical Co., Ltd. 口腔粘膜投与剤
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2068872A1 (de) * 2006-09-08 2009-06-17 Braincells, Inc. Kombinationen mit einem 4-acylaminopyridin-derivat
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US9161909B2 (en) * 2007-08-24 2015-10-20 Axiomedic Ltd. Adhesive compositions for the treatment of xerostomia
US20090053309A1 (en) * 2007-08-24 2009-02-26 Axiomedic Ltd., Gibraltar Adhesive compositions for the treatment of xerostomia
US9597278B2 (en) 2008-11-13 2017-03-21 David A. Hamlin Compositions and methods for alleviating hyposalivation and for providing oral comfort
US9884082B2 (en) 2008-11-13 2018-02-06 David A. Hamlin Compositions and methods for alleviating hyposalivation and for providing oral comfort
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US8450487B2 (en) * 2010-06-08 2013-05-28 Apicore, Llc Process for the preparation of cis-2-methylspiro (1,3-oxathiolane 5-3′) quinuclidine
CN108601385A (zh) 2015-12-04 2018-09-28 三荣源有限公司 酶修饰的异槲皮苷的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
US5078129A (en) * 1987-05-01 1992-01-07 Research Foundation Of State University Of New York Device for stimulating salivation
IL87234A (en) * 1987-08-13 1992-02-16 Israel Inst Biolog Res Optical isomers of 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine,their preparation and pharmaceutical compositions containing them
US4917674A (en) * 1988-04-04 1990-04-17 Molinoff Henry C Mouth moisturizing device
US4906455A (en) * 1988-04-15 1990-03-06 Wm. Wrigley Jr. Company Method for treating xerostomia employing chewing gum containing relatively insoluble, hydrophobic, food-grade organic acid
US4983378A (en) * 1988-11-22 1991-01-08 Parnell Pharmaceuticals, Inc. Method and composition for treating xerostomia
US4997654A (en) * 1989-08-14 1991-03-05 Warner-Lambert Company Method for increasing salivation for xerostomia patients
JP3018494B2 (ja) * 1990-11-30 2000-03-13 ソニー株式会社 特殊効果装置
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤

Also Published As

Publication number Publication date
KR100322042B1 (ko) 2002-11-04
NO309454B1 (no) 2001-02-05
ES2163474T3 (es) 2002-02-01
AU707236B2 (en) 1999-07-08
EP0689836A1 (de) 1996-01-03
US5580880A (en) 1996-12-03
NO952561L (no) 1995-12-28
KR960000222A (ko) 1996-01-25
JPH0812575A (ja) 1996-01-16
JP2852608B2 (ja) 1999-02-03
AU2324595A (en) 1996-01-11
EP0689836B1 (de) 2001-09-05
CA2152420A1 (en) 1995-12-28
TW401298B (en) 2000-08-11
NO952561D0 (no) 1995-06-26
IL114256A (en) 1999-05-09
DE69522511T2 (de) 2002-05-16
DE69522511D1 (de) 2001-10-11
ATE205085T1 (de) 2001-09-15
DK0689836T3 (da) 2002-05-06
IL114256A0 (en) 1995-10-31
ZA955317B (en) 1996-02-02

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