IL114256A - Pharmaceutical compositions containing spiro (1,3-oxathiolane-5, 3'-quinuclidine for the treatment of xerostomia not caused by sjoergen's syndrome - Google Patents

Pharmaceutical compositions containing spiro (1,3-oxathiolane-5, 3'-quinuclidine for the treatment of xerostomia not caused by sjoergen's syndrome

Info

Publication number
IL114256A
IL114256A IL11425695A IL11425695A IL114256A IL 114256 A IL114256 A IL 114256A IL 11425695 A IL11425695 A IL 11425695A IL 11425695 A IL11425695 A IL 11425695A IL 114256 A IL114256 A IL 114256A
Authority
IL
Israel
Prior art keywords
xerostomia
salivary gland
quinuclidine
treatment
alkyl
Prior art date
Application number
IL11425695A
Other languages
English (en)
Other versions
IL114256A0 (en
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Publication of IL114256A0 publication Critical patent/IL114256A0/xx
Publication of IL114256A publication Critical patent/IL114256A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
IL11425695A 1994-06-27 1995-06-21 Pharmaceutical compositions containing spiro (1,3-oxathiolane-5, 3'-quinuclidine for the treatment of xerostomia not caused by sjoergen's syndrome IL114256A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6168982A JP2852608B2 (ja) 1994-06-27 1994-06-27 口腔乾燥症治療剤

Publications (2)

Publication Number Publication Date
IL114256A0 IL114256A0 (en) 1995-10-31
IL114256A true IL114256A (en) 1999-05-09

Family

ID=15878165

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11425695A IL114256A (en) 1994-06-27 1995-06-21 Pharmaceutical compositions containing spiro (1,3-oxathiolane-5, 3'-quinuclidine for the treatment of xerostomia not caused by sjoergen's syndrome

Country Status (15)

Country Link
US (1) US5580880A (xx)
EP (1) EP0689836B1 (xx)
JP (1) JP2852608B2 (xx)
KR (1) KR100322042B1 (xx)
AT (1) ATE205085T1 (xx)
AU (1) AU707236B2 (xx)
CA (1) CA2152420A1 (xx)
CY (1) CY2290B1 (xx)
DE (1) DE69522511T2 (xx)
DK (1) DK0689836T3 (xx)
ES (1) ES2163474T3 (xx)
IL (1) IL114256A (xx)
NO (1) NO309454B1 (xx)
TW (1) TW401298B (xx)
ZA (1) ZA955317B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618341D0 (en) * 1996-09-03 1996-10-16 Scotia Holdings Plc Method of treatment
JP4447685B2 (ja) * 1999-01-14 2010-04-07 第一三共株式会社 皮膚乾燥症治療剤
JP4909809B2 (ja) * 1999-03-24 2012-04-04 生化学工業株式会社 人工唾液
WO2006013914A1 (ja) * 2004-08-06 2006-02-09 Daiichi Pharmaceutical Co., Ltd. 口腔粘膜投与剤
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
CA2620333A1 (en) * 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス,インコーポレイティド アンジオテンシン調節による神経新生
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
KR20090064418A (ko) * 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US9161909B2 (en) * 2007-08-24 2015-10-20 Axiomedic Ltd. Adhesive compositions for the treatment of xerostomia
US20090053309A1 (en) * 2007-08-24 2009-02-26 Axiomedic Ltd., Gibraltar Adhesive compositions for the treatment of xerostomia
US9597278B2 (en) 2008-11-13 2017-03-21 David A. Hamlin Compositions and methods for alleviating hyposalivation and for providing oral comfort
US9884082B2 (en) 2008-11-13 2018-02-06 David A. Hamlin Compositions and methods for alleviating hyposalivation and for providing oral comfort
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US8450487B2 (en) 2010-06-08 2013-05-28 Apicore, Llc Process for the preparation of cis-2-methylspiro (1,3-oxathiolane 5-3′) quinuclidine
WO2017094910A1 (ja) 2015-12-04 2017-06-08 三栄源エフ・エフ・アイ株式会社 酵素処理イソクエルシトリンの利用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855290A (en) * 1985-05-10 1989-08-08 State Of Israel, Represented By Prime Minister's Office, Israel Institute For Biological Research Derivatives of quinuclidine
US5078129A (en) * 1987-05-01 1992-01-07 Research Foundation Of State University Of New York Device for stimulating salivation
IL87234A (en) 1987-08-13 1992-02-16 Israel Inst Biolog Res Optical isomers of 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine,their preparation and pharmaceutical compositions containing them
US4917674A (en) * 1988-04-04 1990-04-17 Molinoff Henry C Mouth moisturizing device
US4906455A (en) * 1988-04-15 1990-03-06 Wm. Wrigley Jr. Company Method for treating xerostomia employing chewing gum containing relatively insoluble, hydrophobic, food-grade organic acid
US4983378A (en) * 1988-11-22 1991-01-08 Parnell Pharmaceuticals, Inc. Method and composition for treating xerostomia
US4997654A (en) * 1989-08-14 1991-03-05 Warner-Lambert Company Method for increasing salivation for xerostomia patients
JP3018494B2 (ja) * 1990-11-30 2000-03-13 ソニー株式会社 特殊効果装置
JP2683783B2 (ja) * 1992-07-10 1997-12-03 雪印乳業株式会社 シェーグレン症候群治療剤

Also Published As

Publication number Publication date
JPH0812575A (ja) 1996-01-16
JP2852608B2 (ja) 1999-02-03
KR960000222A (ko) 1996-01-25
NO309454B1 (no) 2001-02-05
IL114256A0 (en) 1995-10-31
ATE205085T1 (de) 2001-09-15
EP0689836A1 (en) 1996-01-03
NO952561L (no) 1995-12-28
DE69522511D1 (de) 2001-10-11
ZA955317B (en) 1996-02-02
TW401298B (en) 2000-08-11
AU2324595A (en) 1996-01-11
ES2163474T3 (es) 2002-02-01
DE69522511T2 (de) 2002-05-16
CA2152420A1 (en) 1995-12-28
AU707236B2 (en) 1999-07-08
CY2290B1 (en) 2003-07-04
NO952561D0 (no) 1995-06-26
KR100322042B1 (ko) 2002-11-04
DK0689836T3 (da) 2002-05-06
US5580880A (en) 1996-12-03
EP0689836B1 (en) 2001-09-05

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Legal Events

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KB Patent renewed
KB Patent renewed
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MM9K Patent not in force due to non-payment of renewal fees