CY2247B1 - Indole derivative - Google Patents

Indole derivative

Info

Publication number
CY2247B1
CY2247B1 CY0100039A CY0100039A CY2247B1 CY 2247 B1 CY2247 B1 CY 2247B1 CY 0100039 A CY0100039 A CY 0100039A CY 0100039 A CY0100039 A CY 0100039A CY 2247 B1 CY2247 B1 CY 2247B1
Authority
CY
Cyprus
Prior art keywords
lower alkoxy
alkoxy
alkoxycarbonyl
indole derivative
carboxy
Prior art date
Application number
CY0100039A
Other languages
English (en)
Inventor
Shiro Kato
Hiroshi Harada
Yoshimi Hirokawa
Naoyuki Yoshida
Hitoshi Kawashima
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of CY2247B1 publication Critical patent/CY2247B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CY0100039A 1994-11-29 2001-11-20 Indole derivative CY2247B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP06321402 1994-11-29

Publications (1)

Publication Number Publication Date
CY2247B1 true CY2247B1 (en) 2003-07-04

Family

ID=18132155

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0100039A CY2247B1 (en) 1994-11-29 2001-11-20 Indole derivative

Country Status (29)

Country Link
US (1) US5817689A (hu)
EP (1) EP0801059B1 (hu)
JP (1) JP3100165B2 (hu)
KR (1) KR100388747B1 (hu)
CN (1) CN1070477C (hu)
AT (1) ATE202559T1 (hu)
AU (1) AU688165B2 (hu)
BR (1) BR9509827A (hu)
CA (1) CA2206307A1 (hu)
CY (1) CY2247B1 (hu)
CZ (1) CZ290871B6 (hu)
DE (1) DE69521529T2 (hu)
DK (1) DK0801059T3 (hu)
ES (1) ES2159648T3 (hu)
FI (1) FI972275A0 (hu)
GR (1) GR3036148T3 (hu)
HK (1) HK1003886A1 (hu)
HU (1) HUT77308A (hu)
IL (1) IL116178A (hu)
NO (1) NO309648B1 (hu)
NZ (1) NZ295749A (hu)
PL (1) PL181963B1 (hu)
PT (1) PT801059E (hu)
RO (1) RO118426B1 (hu)
RU (1) RU2137759C1 (hu)
SK (1) SK281865B6 (hu)
TW (1) TW349091B (hu)
WO (1) WO1996016938A1 (hu)
ZA (1) ZA9510130B (hu)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010580A1 (es) * 1999-09-03 2001-05-25 Takeda Chemical Industries Ltd Composicion farmaceutica para tratar la diabetes
CZ20021833A3 (cs) * 1999-11-30 2003-02-12 Dainippon Pharmaceutical Co., Ltd. Krystal [3-[(2R)-[[(2R)-(3-chlorfenyl)-2-hydroxy-ethyl]amino]propyl]-1H-indol-7-yloxy] kyseliny octové a jej obsahující granule, pevný prostředek, tableta, dráždivé činidlo a činidlo pro léčbu
US6458824B1 (en) * 1999-11-30 2002-10-01 Dainippon Pharmaceutical Co., Ltd. Solid preparation
JP2004331500A (ja) * 2001-02-16 2004-11-25 Dainippon Pharmaceut Co Ltd 血中濃度制御製剤
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
US20040018959A1 (en) * 2002-05-02 2004-01-29 Randall S. Hickle System and methods of lipid removal from the body
EP1514869A1 (en) * 2002-06-12 2005-03-16 Sumitomo Pharmaceuticals Company, Limited Indole, indazole, and benzazole derivative
EP1927594A1 (en) * 2003-01-14 2008-06-04 Arena Pharmaceuticals, Inc. 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
NZ540612A (en) * 2003-01-14 2008-02-29 Arena Pharm Inc 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
US7098231B2 (en) 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
WO2004089936A1 (ja) * 2003-04-10 2004-10-21 Dainippon Pharmaceutical Co., Ltd. ヘテロアリールスルホン酸アニリド誘導体及びそれを含有する医薬組成物
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
DK1718608T3 (da) 2004-02-20 2013-10-14 Boehringer Ingelheim Int Virale polymeraseinhibitorer
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
US8076365B2 (en) 2005-08-12 2011-12-13 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
EP2619198A1 (en) 2010-09-22 2013-07-31 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar
JP6660668B2 (ja) * 2014-06-24 2020-03-11 花王株式会社 Ucp−1発現促進剤
WO2015199097A1 (ja) * 2014-06-24 2015-12-30 花王株式会社 Ucp-1発現促進剤
US10758519B2 (en) 2014-06-24 2020-09-01 Kao Corporation UCP-1 expression promoter
EP4445956A2 (en) 2015-01-06 2024-10-16 Arena Pharmaceuticals, Inc. Compound for use in treating conditions related to the s1p1 receptor
WO2016209809A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB861428A (en) * 1958-07-14 1961-02-22 Searle & Co Improvements in or relating to indole derivatives
US4055658A (en) * 1976-05-17 1977-10-25 Mead Johnson & Company Cyanomethylphenethanolamines
DE3061334D1 (en) * 1979-06-16 1983-01-20 Beecham Group Plc Ethanamine derivatives, their preparation and use in pharmaceutical compositions
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
JPH06345731A (ja) * 1992-04-28 1994-12-20 Dainippon Pharmaceut Co Ltd 2−〔2−(インドール−3−イル)エチルアミノ〕−1−フェニルエタノール誘導体
JPH0634531A (ja) * 1992-07-14 1994-02-08 Yokogawa Electric Corp 赤外線水分計

Also Published As

Publication number Publication date
HUT77308A (hu) 1998-03-30
NO972427L (no) 1997-07-28
JP3100165B2 (ja) 2000-10-16
DE69521529D1 (de) 2001-08-02
TW349091B (en) 1999-01-01
DK0801059T3 (da) 2001-09-24
CN1174549A (zh) 1998-02-25
WO1996016938A1 (fr) 1996-06-06
EP0801059B1 (en) 2001-06-27
IL116178A (en) 2000-07-26
PL181963B1 (pl) 2001-10-31
PT801059E (pt) 2001-10-30
NO309648B1 (no) 2001-03-05
EP0801059A1 (en) 1997-10-15
ES2159648T3 (es) 2001-10-16
SK65697A3 (en) 1998-01-14
KR100388747B1 (ko) 2004-03-30
SK281865B6 (sk) 2001-08-06
BR9509827A (pt) 1997-09-30
AU3936695A (en) 1996-06-19
US5817689A (en) 1998-10-06
MX9703858A (es) 1997-09-30
CZ165597A3 (en) 1997-11-12
CN1070477C (zh) 2001-09-05
FI972275A (fi) 1997-05-29
CZ290871B6 (cs) 2002-11-13
RO118426B1 (ro) 2003-05-30
RU2137759C1 (ru) 1999-09-20
IL116178A0 (en) 1996-01-31
DE69521529T2 (de) 2001-10-11
ATE202559T1 (de) 2001-07-15
CA2206307A1 (en) 1996-06-06
HK1003886A1 (en) 1998-11-13
AU688165B2 (en) 1998-03-05
EP0801059A4 (en) 1998-01-21
ZA9510130B (en) 1996-06-11
FI972275A0 (fi) 1997-05-29
NZ295749A (en) 1998-05-27
NO972427D0 (no) 1997-05-28
PL320461A1 (en) 1997-09-29
GR3036148T3 (en) 2001-09-28

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