CY1121078T1 - Ανοργανα νανοσωματιδια υψηλης πυκνοτητας για καταστροφη κυτταρων in-vivo - Google Patents
Ανοργανα νανοσωματιδια υψηλης πυκνοτητας για καταστροφη κυτταρων in-vivoInfo
- Publication number
- CY1121078T1 CY1121078T1 CY181101377T CY181101377T CY1121078T1 CY 1121078 T1 CY1121078 T1 CY 1121078T1 CY 181101377 T CY181101377 T CY 181101377T CY 181101377 T CY181101377 T CY 181101377T CY 1121078 T1 CY1121078 T1 CY 1121078T1
- Authority
- CY
- Cyprus
- Prior art keywords
- particles
- health
- vivo
- high density
- relates
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Radiation-Therapy Devices (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Η παρούσα αίτηση σχετίζεται με νέα διεγέρσιμα σωματίδια τα οποία μπορεί να χρησιμοποιηθούν στον τομέα της υγείας. Πιο συγκεκριμένα σχετίζεται με σωματίδια τα οποία μπορεί να παράγουν ηλεκτρόνια και/ή υψηλής ενέργειας φωτόνιο όταν διεγερθούν με ιονίζουσες ακτινοβολίες όπως Ακτίνες Χ, Ακτίνες γάμμα, ραδιενεργό ισότοπο και/ή δέσμες ηλεκτρονίων, και με τις χρήσεις αυτών στην υγεία, ειδικότερα στην ανθρώπινη υγεία. Τα σωματίδια της εφεύρεσης αποτελούνται από ένα ανόργανο υλικό το οποίο περιλαμβάνει οξυγόνο, πιο συγκεκριμένα ένα οξείδιο, με το εν λόγω υλικό να έχει μία επαρκή πυκνότητα, και μπορεί να ενεργοποιηθούν in vitro, ex vivo, ή in vivo, με ελεγχόμενη εξωτερική διέγερση, για να διαταράξουν, να τροποποιήσουν ή να καταστρέψουν κύτταρα, ιστούς ή όργανα στόχους. Η εφεύρεση επίσης σχετίζεται με μεθόδους για την παραγωγή των εν λόγω σωματιδίων, και με φαρμακευτικές συνθέσεις ή συνθέσεις ιατρικών συσκευών οι οποίες τα περιέχουν.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08157686A EP2130553A1 (en) | 2008-06-05 | 2008-06-05 | Inorganic nanoparticles of high density to destroy cells in-vivo |
| US6020208P | 2008-06-10 | 2008-06-10 | |
| EP09757595.5A EP2300054B1 (en) | 2008-06-05 | 2009-06-04 | Inorganic nanoparticles of high density to destroy cells in-vivo |
| PCT/EP2009/056880 WO2009147214A2 (en) | 2008-06-05 | 2009-06-04 | Inorganic nanoparticles, preparation and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1121078T1 true CY1121078T1 (el) | 2019-12-11 |
Family
ID=39734334
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161101109T CY1118217T1 (el) | 2008-06-05 | 2016-11-01 | Ανοργανα νανοσωματιδια υψηλης πυκνοτητας για καταστροφη κυτταρων in-vivo |
| CY181101377T CY1121078T1 (el) | 2008-06-05 | 2018-12-19 | Ανοργανα νανοσωματιδια υψηλης πυκνοτητας για καταστροφη κυτταρων in-vivo |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161101109T CY1118217T1 (el) | 2008-06-05 | 2016-11-01 | Ανοργανα νανοσωματιδια υψηλης πυκνοτητας για καταστροφη κυτταρων in-vivo |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US8845507B2 (el) |
| EP (4) | EP2130553A1 (el) |
| JP (1) | JP5734181B2 (el) |
| KR (1) | KR101639281B1 (el) |
| CN (1) | CN102056628B (el) |
| AU (1) | AU2009254550B2 (el) |
| BR (1) | BRPI0913410B1 (el) |
| CA (1) | CA2727576C (el) |
| CY (2) | CY1118217T1 (el) |
| DK (2) | DK2300054T3 (el) |
| EA (1) | EA023012B1 (el) |
| ES (2) | ES2702249T3 (el) |
| HR (2) | HRP20161465T8 (el) |
| HU (2) | HUE040247T2 (el) |
| IL (1) | IL209625A (el) |
| LT (2) | LT3150227T (el) |
| MA (1) | MA32453B1 (el) |
| MX (1) | MX2010013322A (el) |
| NZ (1) | NZ589888A (el) |
| PL (2) | PL3150227T3 (el) |
| PT (2) | PT2300054T (el) |
| SG (1) | SG10201405288WA (el) |
| SI (2) | SI2300054T1 (el) |
| TR (1) | TR201819077T4 (el) |
| WO (1) | WO2009147214A2 (el) |
| ZA (1) | ZA201100082B (el) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004075975A2 (en) * | 2003-02-24 | 2004-09-10 | Pomper Mark E | Mobile radiation treatment vehicle and method |
| US8657354B2 (en) | 2006-05-19 | 2014-02-25 | Breya, Llc. | Mobile radiation therapy |
| US8459714B2 (en) | 2006-05-19 | 2013-06-11 | Breya, Llc. | Mobile radiation therapy |
| US9399075B2 (en) | 2008-12-29 | 2016-07-26 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
| US8728440B2 (en) | 2012-08-23 | 2014-05-20 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
| EP2275137A1 (en) * | 2009-07-10 | 2011-01-19 | Nanobiotix | Metallic nanoparticles, preparation and uses thereof |
| US9585840B1 (en) | 2009-07-10 | 2017-03-07 | University Of Central Florida Research Foundation, Inc. | Redox active cerium oxide nanoparticles and associated methods |
| CN102870235B (zh) * | 2009-11-10 | 2016-11-23 | 免疫之光有限责任公司 | 用于从包括用于上变频的射频、微波能量和磁感应源的各种能量源产生发射光的上下变频系统 |
| KR20180100248A (ko) | 2010-04-23 | 2018-09-07 | 픽셀리전트 테크놀로지스 엘엘씨 | 나노결정의 합성, 캐핑 및 분산 |
| US8920675B2 (en) | 2010-10-27 | 2014-12-30 | Pixelligent Technologies, Llc | Synthesis, capping and dispersion of nanocrystals |
| US9359689B2 (en) | 2011-10-26 | 2016-06-07 | Pixelligent Technologies, Llc | Synthesis, capping and dispersion of nanocrystals |
| SG11201403096VA (en) | 2011-12-16 | 2014-07-30 | Nanobiotix | Nanoparticles comprising metallic and hafnium oxide materials, preparation and uses thereof |
| WO2013188755A2 (en) * | 2012-06-14 | 2013-12-19 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods for non-invasive detection and treatment of hypoxic cells in vivo |
| US8821838B2 (en) | 2012-08-23 | 2014-09-02 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
| KR102225239B1 (ko) * | 2013-01-25 | 2021-03-09 | 나노비오?笭? | 암 치료용 이온화 방사선과 조합된 무기 나노입자 조성물 |
| RU2015135133A (ru) * | 2013-02-19 | 2017-03-24 | Нэшенел Хелс Рисёч Инститьютс | Заключенные в оболочку нанокластеры платины для противораковых химиотерапевтических средств |
| BR112015029853A2 (pt) | 2013-05-30 | 2017-07-25 | Nanobiotix | uso de uma composição farmacêutica |
| MA38709A1 (fr) | 2013-06-20 | 2018-05-31 | Nanobiotix | Compositions et procédés pour une utilisation en diagnostic médical |
| EP2886128A1 (en) | 2013-12-20 | 2015-06-24 | Nanobiotix | Pharmaceutical composition comprising nanoparticles, preparation and uses thereof |
| EP3229776B1 (en) | 2014-11-25 | 2023-06-28 | Curadigm Sas | Pharmaceutical composition combining at least two distinct nanoparticles and a pharmaceutical compound, preparation and uses thereof |
| JP6789960B2 (ja) | 2014-11-25 | 2020-11-25 | キュラディグム・エスアエスＣｕｒａｄｉｇｍ Ｓａｓ | 医薬組成物、その調製及び使用 |
| AR102778A1 (es) | 2014-11-25 | 2017-03-22 | Nanobiotix | Composición farmacéutica, su preparación y sus usos |
| US11304902B2 (en) | 2014-11-25 | 2022-04-19 | Curadigm Sas | Pharmaceutical compositions, preparation and uses thereof |
| SG11201704143YA (en) | 2014-11-25 | 2017-06-29 | Nanobiotix | Pharmaceutical composition, preparation and uses thereof |
| EP3721887A1 (en) * | 2015-01-08 | 2020-10-14 | Purdue Research Foundation | Non-toxic formulations of radio-luminescent nanoparticles for use as cancer radio-sensitizing agents |
| AR104806A1 (es) * | 2015-05-28 | 2017-08-16 | Nanobiotix | Nanopartículas para uso como vacuna terapéutica |
| US11389536B2 (en) | 2015-07-17 | 2022-07-19 | BioCurity Pharmaceuticals Inc. | Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent |
| CN109010828B (zh) * | 2018-10-12 | 2020-10-20 | 中国科学院高能物理研究所 | 一种二硫化钼/二氧化铪的复合纳米材料、其制备方法及用途 |
| CN109616308B (zh) * | 2018-11-07 | 2020-09-04 | 湖北第二师范学院 | 一种球形纳米氧化铱dna提取磁性粉末及其生产方法 |
| CN109771645B (zh) * | 2019-03-07 | 2021-08-24 | 广西师范大学 | 一种二氧化钌复合卵清蛋白纳米材料的制备及其应用 |
| US20230211175A1 (en) * | 2020-05-26 | 2023-07-06 | Nanobiotix S.A. | Nanoparticles, ionizing radiation and innovative therapeutic combinations thereof |
| MX2023005314A (es) * | 2020-11-05 | 2023-05-25 | Nanobiotix | Composiciones de nanoparticulas para tratamiento de cancer. |
| US20240000940A1 (en) * | 2020-12-01 | 2024-01-04 | Nanobiotix S.A. | Porous, high-z and carbon-free particles as radioenhancers |
| WO2024126383A1 (en) | 2022-12-12 | 2024-06-20 | Nanobiotix (Nanobiotix S.A.) | Novel metal oxide nanoparticles and compositions thereof for use as radioenhancers or for visualizing biological tissue |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6287526A (ja) * | 1985-10-11 | 1987-04-22 | Akira Fujishima | 抗腫瘍剤 |
| US6645464B1 (en) | 1998-07-30 | 2003-11-11 | James F. Hainfeld | Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy |
| JP2007514736A (ja) | 2003-12-17 | 2007-06-07 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 紫外線放射ナノ粒子を用いた放射線治療および医学画像 |
| FR2869803B1 (fr) * | 2004-05-10 | 2006-07-28 | Nanobiotix Sarl | Particules activables, preparation et utilisations |
| US20070092927A1 (en) * | 2005-06-13 | 2007-04-26 | University Of Dayton | Photocatalytic particles with directed and controlled redox activity |
| JP2007075696A (ja) * | 2005-09-13 | 2007-03-29 | Mitsubishi Materials Corp | 多孔質光触媒膜 |
| EP2040752A2 (en) * | 2006-07-10 | 2009-04-01 | Philips Intellectual Property & Standards GmbH | Core-shell nanoparticles for thearapy and imaging purposes |
| EP1920784A1 (en) * | 2006-11-13 | 2008-05-14 | Koninklijke Philips Electronics N.V. | Radiation sensitizers in ionizing radiation therapy and imaging |
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2008
- 2008-06-05 EP EP08157686A patent/EP2130553A1/en not_active Withdrawn
-
2009
- 2009-06-04 US US12/994,162 patent/US8845507B2/en active Active
- 2009-06-04 DK DK09757595.5T patent/DK2300054T3/en active
- 2009-06-04 EP EP16187263.5A patent/EP3150227B1/en active Active
- 2009-06-04 SI SI200931555A patent/SI2300054T1/sl unknown
- 2009-06-04 EA EA201071429A patent/EA023012B1/ru unknown
- 2009-06-04 ES ES16187263T patent/ES2702249T3/es active Active
- 2009-06-04 LT LTEP16187263.5T patent/LT3150227T/lt unknown
- 2009-06-04 CA CA2727576A patent/CA2727576C/en active Active
- 2009-06-04 SG SG10201405288WA patent/SG10201405288WA/en unknown
- 2009-06-04 AU AU2009254550A patent/AU2009254550B2/en active Active
- 2009-06-04 PT PT97575955T patent/PT2300054T/pt unknown
- 2009-06-04 SI SI200931905T patent/SI3150227T1/sl unknown
- 2009-06-04 BR BRPI0913410-7A patent/BRPI0913410B1/pt active IP Right Grant
- 2009-06-04 HU HUE16187263A patent/HUE040247T2/hu unknown
- 2009-06-04 PT PT16187263T patent/PT3150227T/pt unknown
- 2009-06-04 PL PL16187263T patent/PL3150227T3/pl unknown
- 2009-06-04 DK DK16187263.5T patent/DK3150227T3/en active
- 2009-06-04 EP EP09757595.5A patent/EP2300054B1/en active Active
- 2009-06-04 HU HUE09757595A patent/HUE030669T2/en unknown
- 2009-06-04 CN CN2009801211030A patent/CN102056628B/zh active Active
- 2009-06-04 EP EP18203014.8A patent/EP3461502A1/en active Pending
- 2009-06-04 MX MX2010013322A patent/MX2010013322A/es active IP Right Grant
- 2009-06-04 WO PCT/EP2009/056880 patent/WO2009147214A2/en active Application Filing
- 2009-06-04 LT LTEP09757595.5T patent/LT2300054T/lt unknown
- 2009-06-04 TR TR2018/19077T patent/TR201819077T4/tr unknown
- 2009-06-04 ES ES09757595.5T patent/ES2602048T3/es active Active
- 2009-06-04 JP JP2011512129A patent/JP5734181B2/ja active Active
- 2009-06-04 NZ NZ589888A patent/NZ589888A/en unknown
- 2009-06-04 KR KR1020117000259A patent/KR101639281B1/ko active IP Right Grant
- 2009-06-04 PL PL09757595T patent/PL2300054T3/pl unknown
-
2010
- 2010-11-29 IL IL209625A patent/IL209625A/en active IP Right Grant
-
2011
- 2011-01-04 ZA ZA2011/00082A patent/ZA201100082B/en unknown
- 2011-01-04 MA MA33490A patent/MA32453B1/fr unknown
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2016
- 2016-11-01 CY CY20161101109T patent/CY1118217T1/el unknown
- 2016-11-07 HR HRP20161465TT patent/HRP20161465T8/hr unknown
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2018
- 2018-11-27 HR HRP20181993TT patent/HRP20181993T1/hr unknown
- 2018-12-19 CY CY181101377T patent/CY1121078T1/el unknown
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