TR201819077T4 - İn-Vivo Hücrelerin Yok Edilmesi İçin Yüksek Yoğunluğa Sahip İnorganik Nanopartiküller - Google Patents
İn-Vivo Hücrelerin Yok Edilmesi İçin Yüksek Yoğunluğa Sahip İnorganik Nanopartiküller Download PDFInfo
- Publication number
- TR201819077T4 TR201819077T4 TR2018/19077T TR201819077T TR201819077T4 TR 201819077 T4 TR201819077 T4 TR 201819077T4 TR 2018/19077 T TR2018/19077 T TR 2018/19077T TR 201819077 T TR201819077 T TR 201819077T TR 201819077 T4 TR201819077 T4 TR 201819077T4
- Authority
- TR
- Turkey
- Prior art keywords
- particles
- vivo
- destruction
- relates
- high density
- Prior art date
Links
- 238000001727 in vivo Methods 0.000 title abstract 3
- 230000006378 damage Effects 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 238000010894 electron beam technology Methods 0.000 abstract 1
- 229910010272 inorganic material Inorganic materials 0.000 abstract 1
- 239000011147 inorganic material Substances 0.000 abstract 1
- 230000005865 ionizing radiation Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/244—Lanthanides; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
Abstract
Mevcut buluş, sağlık sektöründe kullanılabilen yenilikçi uyarılabilir partiküllerle ilgilidir. Daha belirgin olarak, X Işınları ve/veya elektron huzmeleri gibi iyonize edici radyasyonlar tarafından uyarıldığında, elektronları ve/veya yüksek enerji fotonlarını üretebilen partiküllerle ve özellikle insan sağlığında olmak üzere, sağlıkta bunların kullanımları ile ilgilidir. Yenilikçi partiküller, söz konusu maddenin yeterli bir yoğunluğa sahip olduğu oksijeni içeren inorganik bir maddeden oluşturulmaktadır ve hedef hücrelerin, dokuların veya organların rahatsız edilmesi, değiştirilmesi veya yok edilmesi için kontrol edilebilir harici uyarım ile canlı dışı, ex vivo veya in vivo olarak aktif hale getirilebilir. Buluş ayrıca, söz konusu partiküllerin üretimi için olan yöntemlerle ilgilidir ve aynısını içeren farmasötik bileşimler ile ilgilidir.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08157686A EP2130553A1 (en) | 2008-06-05 | 2008-06-05 | Inorganic nanoparticles of high density to destroy cells in-vivo |
US6020208P | 2008-06-10 | 2008-06-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201819077T4 true TR201819077T4 (tr) | 2019-01-21 |
Family
ID=39734334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2018/19077T TR201819077T4 (tr) | 2008-06-05 | 2009-06-04 | İn-Vivo Hücrelerin Yok Edilmesi İçin Yüksek Yoğunluğa Sahip İnorganik Nanopartiküller |
Country Status (26)
Country | Link |
---|---|
US (1) | US8845507B2 (tr) |
EP (4) | EP2130553A1 (tr) |
JP (1) | JP5734181B2 (tr) |
KR (1) | KR101639281B1 (tr) |
CN (1) | CN102056628B (tr) |
AU (1) | AU2009254550B2 (tr) |
BR (1) | BRPI0913410B1 (tr) |
CA (1) | CA2727576C (tr) |
CY (2) | CY1118217T1 (tr) |
DK (2) | DK2300054T3 (tr) |
EA (1) | EA023012B1 (tr) |
ES (2) | ES2702249T3 (tr) |
HR (2) | HRP20161465T8 (tr) |
HU (2) | HUE040247T2 (tr) |
IL (1) | IL209625A (tr) |
LT (2) | LT3150227T (tr) |
MA (1) | MA32453B1 (tr) |
MX (1) | MX2010013322A (tr) |
NZ (1) | NZ589888A (tr) |
PL (2) | PL2300054T3 (tr) |
PT (2) | PT2300054T (tr) |
SG (1) | SG10201405288WA (tr) |
SI (2) | SI3150227T1 (tr) |
TR (1) | TR201819077T4 (tr) |
WO (1) | WO2009147214A2 (tr) |
ZA (1) | ZA201100082B (tr) |
Families Citing this family (33)
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WO2004075975A2 (en) * | 2003-02-24 | 2004-09-10 | Pomper Mark E | Mobile radiation treatment vehicle and method |
US8657354B2 (en) | 2006-05-19 | 2014-02-25 | Breya, Llc. | Mobile radiation therapy |
US8459714B2 (en) | 2006-05-19 | 2013-06-11 | Breya, Llc. | Mobile radiation therapy |
US9399075B2 (en) | 2008-12-29 | 2016-07-26 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
US8728440B2 (en) | 2012-08-23 | 2014-05-20 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
EP2275137A1 (en) | 2009-07-10 | 2011-01-19 | Nanobiotix | Metallic nanoparticles, preparation and uses thereof |
US9585840B1 (en) | 2009-07-10 | 2017-03-07 | University Of Central Florida Research Foundation, Inc. | Redox active cerium oxide nanoparticles and associated methods |
WO2011060033A1 (en) * | 2009-11-10 | 2011-05-19 | Immunolight, L.L.C. | Up and down coversion systems for production of emitted light from various energy sources including radio frequency, microwave energy and magnetic induction sources for upconversion |
JP6178725B2 (ja) | 2010-04-23 | 2017-08-09 | ピクセリジェント・テクノロジーズ,エルエルシー | ナノ結晶の合成、キャップ形成および分散 |
US8920675B2 (en) | 2010-10-27 | 2014-12-30 | Pixelligent Technologies, Llc | Synthesis, capping and dispersion of nanocrystals |
US9359689B2 (en) | 2011-10-26 | 2016-06-07 | Pixelligent Technologies, Llc | Synthesis, capping and dispersion of nanocrystals |
PL2790682T3 (pl) | 2011-12-16 | 2019-08-30 | Nanobiotix | Nanocząstki zawierające materiał metaliczny i materiał tlenku hafnu, ich wytwarzanie i zastosowanie |
EP2877212A4 (en) * | 2012-06-14 | 2016-04-27 | Univ Arkansas | COMPOSITIONS AND METHODS FOR NON-INVASIVE DETECTION AND TREATMENT OF IN VIVO HYPOXIC CELLS |
US8821838B2 (en) | 2012-08-23 | 2014-09-02 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
SG11201505277VA (en) * | 2013-01-25 | 2015-08-28 | Nanobiotix | Inorganic nanoparticles compositions in combination with ionizing radiations for treating cancer |
RU2015135133A (ru) * | 2013-02-19 | 2017-03-24 | Нэшенел Хелс Рисёч Инститьютс | Заключенные в оболочку нанокластеры платины для противораковых химиотерапевтических средств |
EA038671B1 (ru) | 2013-05-30 | 2021-10-01 | Кюрадигм Сас | Способ повышения терапевтической или профилактической эффективности представляющего интерес фармацевтического соединения |
MX2015017774A (es) * | 2013-06-20 | 2016-03-31 | Nanobiotix | Composiciones y metodos para el uso en el diagnostico medico. |
EP2886128A1 (en) * | 2013-12-20 | 2015-06-24 | Nanobiotix | Pharmaceutical composition comprising nanoparticles, preparation and uses thereof |
WO2016083331A1 (en) | 2014-11-25 | 2016-06-02 | Nanobiotix | Pharmaceutical composition, preparation and uses thereof |
NZ769187A (en) | 2014-11-25 | 2023-07-28 | Curadigm Sas | Pharmaceutical composition, preparation and uses thereof |
FI3229776T3 (fi) | 2014-11-25 | 2023-08-15 | Curadigm Sas | Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt |
BR112017010933A2 (pt) | 2014-11-25 | 2018-02-14 | Nanobiotix | composição farmacêutica |
HUE056175T2 (hu) | 2014-11-25 | 2022-01-28 | Curadigm Sas | Gyógyászati készítmények, elõállításuk és alkalmazásaik |
EP3721887A1 (en) * | 2015-01-08 | 2020-10-14 | Purdue Research Foundation | Non-toxic formulations of radio-luminescent nanoparticles for use as cancer radio-sensitizing agents |
NZ738527A (en) * | 2015-05-28 | 2022-07-01 | Nanobiotix | Nanoparticles for use as a therapeutic vaccine |
US11389536B2 (en) | 2015-07-17 | 2022-07-19 | BioCurity Pharmaceuticals Inc. | Treatment of cancer with a combination of radiation, cerium oxide nanoparticles, and a chemotherapeutic agent |
CN109010828B (zh) * | 2018-10-12 | 2020-10-20 | 中国科学院高能物理研究所 | 一种二硫化钼/二氧化铪的复合纳米材料、其制备方法及用途 |
CN109616308B (zh) * | 2018-11-07 | 2020-09-04 | 湖北第二师范学院 | 一种球形纳米氧化铱dna提取磁性粉末及其生产方法 |
CN109771645B (zh) * | 2019-03-07 | 2021-08-24 | 广西师范大学 | 一种二氧化钌复合卵清蛋白纳米材料的制备及其应用 |
US20230211175A1 (en) * | 2020-05-26 | 2023-07-06 | Nanobiotix S.A. | Nanoparticles, ionizing radiation and innovative therapeutic combinations thereof |
AU2021374754A1 (en) * | 2020-11-05 | 2023-06-22 | Nanobiotix | Compositions of nanoparticles for treatment of cancer |
CN116615269A (zh) * | 2020-12-01 | 2023-08-18 | 纳米生物技术公司 | 作为辐射增强剂的多孔、高z和无碳颗粒 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6287526A (ja) * | 1985-10-11 | 1987-04-22 | Akira Fujishima | 抗腫瘍剤 |
US6645464B1 (en) | 1998-07-30 | 2003-11-11 | James F. Hainfeld | Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy |
US20070274909A1 (en) | 2003-12-17 | 2007-11-29 | Koninklijke Philips Electronic, N.V. | Radiation Therapy and Medical Imaging Using Uv Emitting Nanoparticles |
FR2869803B1 (fr) * | 2004-05-10 | 2006-07-28 | Nanobiotix Sarl | Particules activables, preparation et utilisations |
US20070092927A1 (en) * | 2005-06-13 | 2007-04-26 | University Of Dayton | Photocatalytic particles with directed and controlled redox activity |
JP2007075696A (ja) * | 2005-09-13 | 2007-03-29 | Mitsubishi Materials Corp | 多孔質光触媒膜 |
JP2009544584A (ja) * | 2006-07-10 | 2009-12-17 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 治療及び画像化を目的とするコア・シェル構造ナノ粒子 |
EP1920784A1 (en) * | 2006-11-13 | 2008-05-14 | Koninklijke Philips Electronics N.V. | Radiation sensitizers in ionizing radiation therapy and imaging |
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2008
- 2008-06-05 EP EP08157686A patent/EP2130553A1/en not_active Withdrawn
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2009
- 2009-06-04 LT LTEP16187263.5T patent/LT3150227T/lt unknown
- 2009-06-04 TR TR2018/19077T patent/TR201819077T4/tr unknown
- 2009-06-04 EP EP18203014.8A patent/EP3461502A1/en active Pending
- 2009-06-04 SI SI200931905T patent/SI3150227T1/sl unknown
- 2009-06-04 SG SG10201405288WA patent/SG10201405288WA/en unknown
- 2009-06-04 CA CA2727576A patent/CA2727576C/en active Active
- 2009-06-04 EA EA201071429A patent/EA023012B1/ru unknown
- 2009-06-04 EP EP09757595.5A patent/EP2300054B1/en active Active
- 2009-06-04 AU AU2009254550A patent/AU2009254550B2/en active Active
- 2009-06-04 DK DK09757595.5T patent/DK2300054T3/en active
- 2009-06-04 LT LTEP09757595.5T patent/LT2300054T/lt unknown
- 2009-06-04 MX MX2010013322A patent/MX2010013322A/es active IP Right Grant
- 2009-06-04 PT PT97575955T patent/PT2300054T/pt unknown
- 2009-06-04 HU HUE16187263A patent/HUE040247T2/hu unknown
- 2009-06-04 SI SI200931555A patent/SI2300054T1/sl unknown
- 2009-06-04 PT PT16187263T patent/PT3150227T/pt unknown
- 2009-06-04 US US12/994,162 patent/US8845507B2/en active Active
- 2009-06-04 ES ES16187263T patent/ES2702249T3/es active Active
- 2009-06-04 WO PCT/EP2009/056880 patent/WO2009147214A2/en active Application Filing
- 2009-06-04 BR BRPI0913410-7A patent/BRPI0913410B1/pt active IP Right Grant
- 2009-06-04 KR KR1020117000259A patent/KR101639281B1/ko active IP Right Grant
- 2009-06-04 HU HUE09757595A patent/HUE030669T2/en unknown
- 2009-06-04 EP EP16187263.5A patent/EP3150227B1/en active Active
- 2009-06-04 DK DK16187263.5T patent/DK3150227T3/en active
- 2009-06-04 PL PL09757595T patent/PL2300054T3/pl unknown
- 2009-06-04 JP JP2011512129A patent/JP5734181B2/ja active Active
- 2009-06-04 ES ES09757595.5T patent/ES2602048T3/es active Active
- 2009-06-04 PL PL16187263T patent/PL3150227T3/pl unknown
- 2009-06-04 NZ NZ589888A patent/NZ589888A/en unknown
- 2009-06-04 CN CN2009801211030A patent/CN102056628B/zh active Active
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2010
- 2010-11-29 IL IL209625A patent/IL209625A/en active IP Right Grant
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2011
- 2011-01-04 ZA ZA2011/00082A patent/ZA201100082B/en unknown
- 2011-01-04 MA MA33490A patent/MA32453B1/fr unknown
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2016
- 2016-11-01 CY CY20161101109T patent/CY1118217T1/el unknown
- 2016-11-07 HR HRP20161465TT patent/HRP20161465T8/hr unknown
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2018
- 2018-11-27 HR HRP20181993TT patent/HRP20181993T1/hr unknown
- 2018-12-19 CY CY181101377T patent/CY1121078T1/el unknown
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