CY1120907T1 - Αντιμυκητιασικοι παραγοντες - Google Patents
Αντιμυκητιασικοι παραγοντεςInfo
- Publication number
- CY1120907T1 CY1120907T1 CY181101227T CY181101227T CY1120907T1 CY 1120907 T1 CY1120907 T1 CY 1120907T1 CY 181101227 T CY181101227 T CY 181101227T CY 181101227 T CY181101227 T CY 181101227T CY 1120907 T1 CY1120907 T1 CY 1120907T1
- Authority
- CY
- Cyprus
- Prior art keywords
- phenyl
- compound
- oxoacetamide
- pyrrol
- piperazin
- Prior art date
Links
- 239000003429 antifungal agent Substances 0.000 title abstract 2
- 229940121375 antifungal agent Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 4
- -1 pyrrole compound Chemical class 0.000 abstract 3
- 125000004194 piperazin-1-yl group Chemical group [H]N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 239000000651 prodrug Substances 0.000 abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 1
- NOGCYMWWKOZATO-UHFFFAOYSA-N 2-(1,5-dimethyl-3-phenylpyrrol-2-yl)-N-[4-[4-(5-fluoropyrimidin-2-yl)piperazin-1-yl]-3-hydroxyphenyl]-2-oxoacetamide Chemical compound CN1C(=C(C=C1C)C1=CC=CC=C1)C(C(=O)NC1=CC(=C(C=C1)N1CCN(CC1)C1=NC=C(C=N1)F)O)=O NOGCYMWWKOZATO-UHFFFAOYSA-N 0.000 abstract 1
- SUFPWYYDCOKDLL-UHFFFAOYSA-N 2-(1,5-dimethyl-3-phenylpyrrol-2-yl)-N-[4-[4-(5-fluoropyrimidin-2-yl)piperazin-1-yl]phenyl]-2-oxoacetamide Chemical compound CN1C(=C(C=C1C)C1=CC=CC=C1)C(C(=O)NC1=CC=C(C=C1)N1CCN(CC1)C1=NC=C(C=N1)F)=O SUFPWYYDCOKDLL-UHFFFAOYSA-N 0.000 abstract 1
- KSPDSMOWMQFPBL-UHFFFAOYSA-N 5-fluoropyrimidine Chemical compound FC1=CN=CN=C1 KSPDSMOWMQFPBL-UHFFFAOYSA-N 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 230000000855 fungicidal effect Effects 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
- A01G7/00—Botany in general
- A01G7/06—Treatment of growing trees or plants, e.g. for preventing decay of wood, for tingeing flowers or wood, for prolonging the life of plants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Ecology (AREA)
- Forests & Forestry (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1420743.5A GB201420743D0 (en) | 2014-11-21 | 2014-11-21 | Antifungal agents |
| GBGB1505891.0A GB201505891D0 (en) | 2015-04-07 | 2015-04-07 | Antifungal agents |
| PCT/GB2015/053546 WO2016079536A1 (en) | 2014-11-21 | 2015-11-20 | Antifungal agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1120907T1 true CY1120907T1 (el) | 2019-12-11 |
Family
ID=54704024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY181101227T CY1120907T1 (el) | 2014-11-21 | 2018-11-21 | Αντιμυκητιασικοι παραγοντες |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US10201524B2 (enExample) |
| EP (2) | EP3415511A1 (enExample) |
| JP (1) | JP6681894B2 (enExample) |
| KR (1) | KR102550341B1 (enExample) |
| CN (2) | CN111096967B (enExample) |
| AU (1) | AU2015348043B2 (enExample) |
| BR (1) | BR112017010439B1 (enExample) |
| CA (1) | CA2982660C (enExample) |
| CY (1) | CY1120907T1 (enExample) |
| DK (1) | DK3221308T3 (enExample) |
| ES (1) | ES2694637T3 (enExample) |
| HR (1) | HRP20182139T1 (enExample) |
| IL (1) | IL252368B (enExample) |
| LT (1) | LT3221308T (enExample) |
| MX (1) | MX2017006447A (enExample) |
| PL (1) | PL3221308T3 (enExample) |
| PT (1) | PT3221308T (enExample) |
| RU (1) | RU2727520C2 (enExample) |
| SI (1) | SI3221308T1 (enExample) |
| WO (1) | WO2016079536A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11039617B2 (en) | 2013-01-30 | 2021-06-22 | Agrofresh Inc. | Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness |
| US10070649B2 (en) | 2013-01-30 | 2018-09-11 | Agrofresh Inc. | Volatile applications against pathogens |
| LT3221308T (lt) | 2014-11-21 | 2018-12-27 | F2G Limited | Priešgrybeliniai agentai |
| US9973887B2 (en) * | 2016-01-21 | 2018-05-15 | Google Llc | Sharing navigation data among co-located computing devices |
| EP3426029B1 (en) | 2016-03-07 | 2023-08-30 | AgroFresh Inc. | Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops |
| GB201609222D0 (en) * | 2016-05-25 | 2016-07-06 | F2G Ltd | Pharmaceutical formulation |
| JP7263313B2 (ja) * | 2017-04-10 | 2023-04-24 | サイネクシス，インコーポレーテッド | 併用される抗真菌剤 |
| CA3120976A1 (en) | 2017-11-30 | 2019-06-06 | Boragen, Inc. | Benzoxaborole compounds and formulations thereof |
| MX2021001904A (es) | 2018-08-18 | 2021-05-27 | Boragen Inc | Formas solidas de benzoxaborol sustituido y composiciones de las mismas. |
| US11819503B2 (en) | 2019-04-23 | 2023-11-21 | F2G Ltd | Method of treating coccidioides infection |
| CA3177435A1 (en) | 2020-05-29 | 2021-12-02 | Arnaud Tessier | Antifungal prodrugs |
| CN112358974B (zh) * | 2020-12-09 | 2022-06-10 | 昆明理工大学 | 一株植物内生真菌黑附球菌fzt214及其应用 |
| CN116675704A (zh) * | 2020-12-21 | 2023-09-01 | 深圳市祥根生物医药有限公司 | 一种吡咯衍生物及其制备方法和用途 |
| CN115109040A (zh) * | 2021-03-23 | 2022-09-27 | 博瑞生物医药（苏州）股份有限公司 | 抗真菌化合物，包含其的药物组合物和制剂，及其应用 |
| CN113429396A (zh) * | 2021-06-08 | 2021-09-24 | 深圳市祥根生物医药有限公司 | 一种五元杂芳环衍生物及其制备方法和用途 |
| TW202521521A (zh) * | 2023-08-08 | 2025-06-01 | 大陸商上海森輝醫藥有限公司 | 一種４－苯基哌啶衍生物及其應用 |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1051723A (enExample) | 1962-04-27 | |||
| US3202654A (en) | 1962-04-27 | 1965-08-24 | Bristol Myers Co | 6-[alpha-hydroxy-and alpha-amino-alpha-pyrrolylacetamido] penicillanic acids and salts thereof |
| US3252970A (en) | 1963-02-27 | 1966-05-24 | Ciba Geigy Corp | Aromatization |
| BE631632A (enExample) | 1963-04-26 | |||
| US3268558A (en) | 1964-11-05 | 1966-08-23 | Ortho Pharma Corp | 1-r-2, 4-dinitropyrroles |
| US3458515A (en) | 1966-07-21 | 1969-07-29 | American Home Prod | Piperazine substituted pyrroles |
| GB1208014A (en) | 1967-03-23 | 1970-10-07 | Glaxo Lab Ltd | Cephalosporins |
| US3573294A (en) | 1968-03-14 | 1971-03-30 | Glaxo Lab Ltd | 7 - (arylglyoxamido)cephalosporanic acids and their salts and alpha-carbonyl derivatives |
| BE790747A (fr) | 1971-10-30 | 1973-02-15 | Whitefin Holding Sa | Stereo-isomeres du 1-(1'-(0-chloro-benzyl)-pyrrol-2'-yl) -2-dibutyl sec.-amino-ethanol et procede pour leur preparation |
| GB1476503A (en) | 1973-06-21 | 1977-06-16 | Sterling Drug Inc | 1-arylamino-and 1-arylimino-pyrroles and preparation thereof |
| BE848465A (fr) | 1976-11-18 | 1977-03-16 | Stereo-isomeres de 1-(1'-benzyl-2' pyrryl)-2-disec.butylaminoethanols a activite analgesique et preparations pharmaceutiques qui les contiennent | |
| US4316900A (en) | 1977-10-05 | 1982-02-23 | Ciba-Geigy Corporation | Piperazinopyrrolobenzodiazepines |
| JPS57142966A (en) | 1981-02-27 | 1982-09-03 | Sagami Chem Res Center | (1-alkyl-2-pyrrolyl)glyoxylic acid amide derivative |
| JPS57144255A (en) | 1981-03-03 | 1982-09-06 | Sagami Chem Res Center | Alpha-methylthio(1-alkyl-2-pyrrolyl)acetamide derivative |
| US4761424A (en) | 1985-10-01 | 1988-08-02 | Warner-Lambert Company | Enolamides, pharmaceutical compositions and methods for treating inflammation |
| FR2601368B1 (fr) | 1986-07-08 | 1989-04-07 | Synthelabo | Derives de nitrofuranne, leur preparation et leur application en therapeutique. |
| AU650953B2 (en) | 1991-03-21 | 1994-07-07 | Novartis Ag | Inhaler |
| US5637592A (en) * | 1994-07-12 | 1997-06-10 | Janssen Pharmaceutica N.V. | Acyl derivatives of azolones |
| US6645976B1 (en) | 1994-07-21 | 2003-11-11 | Eli Lilly And Company | Indolizine SPLA2inhibitors |
| KR19990008109A (ko) | 1995-04-28 | 1999-01-25 | 나가사까 겐지로 | 1,4-이치환 피페리딘 유도체 |
| DE69517160T2 (de) | 1995-06-06 | 2000-11-16 | Agfa-Gevaert N.V., Mortsel | Photographische Materialien |
| JPH09249669A (ja) | 1996-03-13 | 1997-09-22 | Ono Pharmaceut Co Ltd | 縮合ピロール誘導体、およびそれらを有効成分として含有する薬剤 |
| IL135774A0 (en) * | 1997-10-22 | 2001-05-20 | Ponikau Jens | Use of antinfungal agents for the topical treatment of fungus-induced mucositis |
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| PL351749A1 (en) | 1999-05-04 | 2003-06-16 | Janssen Pharmaceutica Nv | Antifungal ethers |
| AU6438800A (en) | 1999-07-30 | 2001-02-19 | Norbert Heske | Cannula system for introducing endoscopic tools in a human or animal body |
| GB0011089D0 (en) | 2000-05-08 | 2000-06-28 | Black James Foundation | Gastrin and cholecystokinin receptor ligands (11) |
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| ES2266497T3 (es) | 2001-06-06 | 2007-03-01 | Vertex Pharmaceuticals Incorporated | Inhibidores de cak y usos de los mismos. |
| EP1405852B9 (en) | 2001-06-20 | 2013-03-27 | Daiichi Sankyo Company, Limited | Diamine derivatives |
| TW200306819A (en) | 2002-01-25 | 2003-12-01 | Vertex Pharma | Indazole compounds useful as protein kinase inhibitors |
| WO2003072028A2 (en) | 2002-02-23 | 2003-09-04 | Bristol-Myers Squibb Company | Method of treating hiv infection by preventing interaction of cd4 and gp120 |
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| JP2006520385A (ja) | 2003-03-13 | 2006-09-07 | シンタ ファーマスーティカルズ コーポレイション | 縮合ピロール化合物 |
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| US20060058286A1 (en) | 2004-09-16 | 2006-03-16 | Mark Krystal | Methods of treating HIV infection |
| EP1863483A4 (en) | 2005-03-31 | 2010-03-31 | Janssen Pharmaceutica Nv | Bicyclic pyrazole compounds as anti-bacteriostatic agents |
| AR053713A1 (es) | 2005-04-20 | 2007-05-16 | Xenon Pharmaceuticals Inc | Compuestos heterociclicos y sus usos como agentes terapeuticos |
| ATE420639T1 (de) * | 2005-05-18 | 2009-01-15 | F2G Ltd | Antimykotische mittel |
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| US7601844B2 (en) | 2006-01-27 | 2009-10-13 | Bristol-Myers Squibb Company | Piperidinyl derivatives as modulators of chemokine receptor activity |
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| GB0623209D0 (en) * | 2006-11-21 | 2007-01-03 | F2G Ltd | Antifungal agents |
| CN101260086B (zh) | 2007-03-06 | 2011-08-10 | 中国科学院上海药物研究所 | 蛋白酪氨酸磷酸酯酶1b抑制剂及其制备方法和用途 |
| GB0710121D0 (en) | 2007-05-25 | 2007-07-04 | F2G Ltd | Antifungal agents |
| CA2720851A1 (en) | 2008-04-15 | 2009-10-22 | Schering Corporation | Oral pharmaceutical compositions in a molecular solid dispersion |
| PL2283006T3 (pl) * | 2008-04-24 | 2015-08-31 | F2G Ltd | Pirolowe środki przeciwgrzybicze |
| GB0809773D0 (en) * | 2008-05-29 | 2008-07-09 | F2G Ltd | Antifungal combination therapy |
| JP2012525403A (ja) | 2009-04-28 | 2012-10-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ＰＫＣθ阻害薬による免疫学的疾患のＥＸ−ＶＩＶＯ治療 |
| EP2636409A1 (en) | 2010-11-05 | 2013-09-11 | Eisai R&D Management Co., Ltd. | Combined pharmaceutical composition as antifungal agent |
| LT3221308T (lt) | 2014-11-21 | 2018-12-27 | F2G Limited | Priešgrybeliniai agentai |
-
2015
- 2015-11-20 LT LTEP15800925.8T patent/LT3221308T/lt unknown
- 2015-11-20 US US15/528,457 patent/US10201524B2/en active Active
- 2015-11-20 DK DK15800925.8T patent/DK3221308T3/en active
- 2015-11-20 ES ES15800925.8T patent/ES2694637T3/es active Active
- 2015-11-20 HR HRP20182139TT patent/HRP20182139T1/hr unknown
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