CY1118603T1 - Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης - Google Patents

Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης

Info

Publication number
CY1118603T1
CY1118603T1 CY20171100169T CY171100169T CY1118603T1 CY 1118603 T1 CY1118603 T1 CY 1118603T1 CY 20171100169 T CY20171100169 T CY 20171100169T CY 171100169 T CY171100169 T CY 171100169T CY 1118603 T1 CY1118603 T1 CY 1118603T1
Authority
CY
Cyprus
Prior art keywords
pulmonary hypertension
treatment
nitroxyl donors
methods
donors
Prior art date
Application number
CY20171100169T
Other languages
Greek (el)
English (en)
Inventor
Vincent J Kalish
Reza Mazhari
Original Assignee
Cardioxyl Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardioxyl Pharmaceuticals, Inc. filed Critical Cardioxyl Pharmaceuticals, Inc.
Publication of CY1118603T1 publication Critical patent/CY1118603T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CY20171100169T 2009-11-23 2017-02-07 Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης CY1118603T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26369809P 2009-11-23 2009-11-23
US26412909P 2009-11-24 2009-11-24
PCT/US2010/057844 WO2011063400A1 (en) 2009-11-23 2010-11-23 Nitroxyl donors for the treatment of pulmonary hypertension

Publications (1)

Publication Number Publication Date
CY1118603T1 true CY1118603T1 (el) 2017-07-12

Family

ID=43513876

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20171100169T CY1118603T1 (el) 2009-11-23 2017-02-07 Δοτες νιτροξυλιου για τη θεραπευτικη αγωγη πνευμονικης υπερτασης

Country Status (15)

Country Link
US (2) US20110160200A1 (enExample)
EP (1) EP2504003B1 (enExample)
JP (2) JP2013511556A (enExample)
CY (1) CY1118603T1 (enExample)
DK (1) DK2504003T3 (enExample)
ES (1) ES2611852T3 (enExample)
HR (1) HRP20170183T1 (enExample)
HU (1) HUE032253T2 (enExample)
LT (1) LT2504003T (enExample)
PL (1) PL2504003T3 (enExample)
PT (1) PT2504003T (enExample)
RS (1) RS55697B1 (enExample)
SI (1) SI2504003T1 (enExample)
SM (2) SMT201700090T1 (enExample)
WO (2) WO2011063339A1 (enExample)

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* Cited by examiner, † Cited by third party
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IN2012DN05028A (enExample) 2009-12-07 2015-10-23 Univ Johns Hopkins
CA2782110A1 (en) * 2009-12-07 2011-06-16 Johns Hopkins University N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives
CN108409662B (zh) 2011-10-17 2021-10-26 约翰斯霍普金斯大学 作为hno供体的经羟胺取代的米氏酸、巴比妥酸和吡唑啉酮衍生物
MX363843B (es) 2013-01-18 2019-04-05 Cardioxyl Pharmaceuticals Inc Composiciones farmaceuticas que comprenden donadores de nitroxilo.
AU2014267360B2 (en) * 2013-05-14 2018-07-05 Active Biotech Ab N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors
EP3126329B1 (en) 2014-01-17 2019-05-29 Cardioxyl Pharmaceuticals Inc. N-hydroxymethanesulfonamide nitroxyl donors
EP3148972B1 (en) 2014-05-27 2019-08-21 Cardioxyl Pharmaceuticals, Inc. Pyrazolone derivatives as nitroxyl donors
US9464061B2 (en) 2014-05-27 2016-10-11 The Johns Hopkins University N-hydroxylamino-barbituric acid derivatives
US10723704B2 (en) 2015-10-19 2020-07-28 Cardioxyl Pharmaceuticals, Inc. Pyrazolone derivatives as nitroxyl donors
US10730828B2 (en) 2015-10-19 2020-08-04 Cardioxyl Pharmaceuticals, Inc. N-hydroxylsulfonamide derivatives as nitroxyl donors
KR20190070912A (ko) 2016-07-28 2019-06-21 더 존스 홉킨스 유니버시티 O-치환된 히드록삼산
CN110520116A (zh) 2017-01-03 2019-11-29 卡尔迪奥克斯尔制药公司 供硝酰化合物的给予方法

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Also Published As

Publication number Publication date
WO2011063400A1 (en) 2011-05-26
SI2504003T1 (sl) 2017-01-31
LT2504003T (lt) 2017-01-25
US20110160200A1 (en) 2011-06-30
US20160081951A1 (en) 2016-03-24
DK2504003T3 (en) 2017-02-20
EP2504003B1 (en) 2016-11-09
SMT201700090T1 (it) 2017-03-08
RS55697B1 (sr) 2017-07-31
JP2013511556A (ja) 2013-04-04
HRP20170183T1 (hr) 2017-03-24
EP2504003A1 (en) 2012-10-03
SMT201700090B (it) 2017-03-08
ES2611852T3 (es) 2017-05-10
PT2504003T (pt) 2017-01-31
JP2016128481A (ja) 2016-07-14
HUE032253T2 (en) 2017-09-28
WO2011063339A1 (en) 2011-05-26
PL2504003T3 (pl) 2017-04-28

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