CY1115952T1 - Παραγωγα πυραζολο πυριδινης σαν αναστολεις της οξειδασης nadρη - Google Patents

Παραγωγα πυραζολο πυριδινης σαν αναστολεις της οξειδασης nadρη

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Publication number
CY1115952T1
CY1115952T1 CY20151100063T CY151100063T CY1115952T1 CY 1115952 T1 CY1115952 T1 CY 1115952T1 CY 20151100063 T CY20151100063 T CY 20151100063T CY 151100063 T CY151100063 T CY 151100063T CY 1115952 T1 CY1115952 T1 CY 1115952T1
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CY
Cyprus
Prior art keywords
pyrasoline
nadri
pyridoline
inhibitions
producers
Prior art date
Application number
CY20151100063T
Other languages
English (en)
Inventor
Patrick Page
Mike Orchard
Benoît Laleu
Original Assignee
Genkyotex Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genkyotex Sa filed Critical Genkyotex Sa
Publication of CY1115952T1 publication Critical patent/CY1115952T1/el

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Abstract

Η παρούσα εφεύρεση αναφέρεται σε παράγωγα πυραζολο πυριδίνης τύπου (I), φαρμακευτική σύνθεση αυτών και στη χρήση τους για τη θεραπεία ή και την πρόληψη διαταραχών ή καταστάσεων που σχετίζονται με οξειδάση NADPH (nicotinamide adenine dinu-cleotide phosphate oxidase).
CY20151100063T 2008-09-23 2015-01-22 Παραγωγα πυραζολο πυριδινης σαν αναστολεις της οξειδασης nadρη CY1115952T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08164857A EP2166010A1 (en) 2008-09-23 2008-09-23 Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
EP09787271.7A EP2344492B1 (en) 2008-09-23 2009-09-22 Pyrazolo pyridine derivatives as nadph oxidase inhibitors

Publications (1)

Publication Number Publication Date
CY1115952T1 true CY1115952T1 (el) 2017-01-25

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CY20151100063T CY1115952T1 (el) 2008-09-23 2015-01-22 Παραγωγα πυραζολο πυριδινης σαν αναστολεις της οξειδασης nadρη

Country Status (22)

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US (3) US9096588B2 (el)
EP (3) EP2166010A1 (el)
JP (2) JP5700837B2 (el)
KR (3) KR101789479B1 (el)
CN (1) CN102159573B (el)
AU (1) AU2009298008B2 (el)
BR (1) BRPI0919330A2 (el)
CA (1) CA2737550C (el)
CY (1) CY1115952T1 (el)
DK (2) DK2860179T3 (el)
ES (2) ES2528096T3 (el)
HK (2) HK1159107A1 (el)
HR (1) HRP20150082T1 (el)
IL (1) IL211892A0 (el)
PL (2) PL2344492T3 (el)
PT (2) PT2860179T (el)
RS (1) RS53781B1 (el)
RU (1) RU2538041C2 (el)
SI (1) SI2344492T1 (el)
SM (1) SMT201500070B (el)
TR (1) TR201808380T4 (el)
WO (1) WO2010035221A1 (el)

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