CY1114472T1 - Ρυθμιστης του υποδοχεα κανναβινοειδων - Google Patents

Ρυθμιστης του υποδοχεα κανναβινοειδων

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Publication number
CY1114472T1
CY1114472T1 CY20131100594T CY131100594T CY1114472T1 CY 1114472 T1 CY1114472 T1 CY 1114472T1 CY 20131100594 T CY20131100594 T CY 20131100594T CY 131100594 T CY131100594 T CY 131100594T CY 1114472 T1 CY1114472 T1 CY 1114472T1
Authority
CY
Cyprus
Prior art keywords
ring
cannivoidic
receptor
regulator
optionally substituted
Prior art date
Application number
CY20131100594T
Other languages
English (en)
Inventor
Shigenori Ohkawa
Tetsuya Tsukamoto
Yoshihiro Kiyota
Mika Goto
Shouzou Yamamoto
Masato Shimojou
Masaki Setou
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of CY1114472T1 publication Critical patent/CY1114472T1/el

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    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Health & Medical Sciences (AREA)
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Abstract

Ένας ρυθμιστής του υποδοχέα κανναβινοειδών ο οποίος περιέχει μια ένωση αντιπροσωπευόμενη από τον Τύπο (Ι0) όπου, Χ είναι ένα άτομο οξυγόνου, κλπ., R0 είναι μια κατ' επιλογή υποκατεστημένη ακυλαμινο ομάδα, δακτύλιος Α0 είναι ένας βενζολικός δακτύλιος ο οποίος μπορεί περαιτέρω να έχει έναν υποκατάστατη εκτός από R0, και ο δακτύλιος Β είναι ένα κατ' επιλογή υποκατεστημένο 5-μελές ετεροκυκλικό, ή ένα άλας αυτής ή ένα προφάρμακο αυτής.
CY20131100594T 2003-06-26 2013-07-15 Ρυθμιστης του υποδοχεα κανναβινοειδων CY1114472T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003182039 2003-06-26
EP04746824.4A EP1637527B1 (en) 2003-06-26 2004-06-25 Cannabinoid receptor modulator

Publications (1)

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CY1114472T1 true CY1114472T1 (el) 2016-10-05

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SI1637527T1 (sl) * 2003-06-26 2013-07-31 Takeda Pharmaceutical Company Limited Modulator kanabinoidnega receptorja
MX2007007453A (es) 2004-12-22 2007-07-19 Ciba Sc Holding Ag Agentes antirradicales.
WO2008089307A2 (en) * 2007-01-18 2008-07-24 Lexicon Pharmaceuticals, Inc. Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer
US8309595B2 (en) * 2007-07-13 2012-11-13 Board Of Regents, The University Of Texas System Hydrazone modulators of cannabinoid receptors
US9079854B2 (en) 2007-07-13 2015-07-14 The Cleveland Clinic Foundation Hydrazone modulators of cannabinoid receptors
US8440832B2 (en) * 2007-07-13 2013-05-14 Board Of Regents, The University Of Texas System Heterocyclic modulators of cannabinoid receptors
US9394267B2 (en) 2007-07-13 2016-07-19 The Cleveland Clinic Foundation Heterocyclic modulators of cannabinoid receptors
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