CY1112874T1 - Φαρμακευτικες μορφες με βελτιωμενες φαρμακοκινητικες ιδιοτητες - Google Patents
Φαρμακευτικες μορφες με βελτιωμενες φαρμακοκινητικες ιδιοτητεςInfo
- Publication number
- CY1112874T1 CY1112874T1 CY20121100558T CY121100558T CY1112874T1 CY 1112874 T1 CY1112874 T1 CY 1112874T1 CY 20121100558 T CY20121100558 T CY 20121100558T CY 121100558 T CY121100558 T CY 121100558T CY 1112874 T1 CY1112874 T1 CY 1112874T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pharmacokinetic properties
- pharmaceutical forms
- improved pharmacokinetic
- vardenafil
- plateau
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Η παρούσα αίτηση αφορά νέες φαρμακευτικές χημικές συνθέσεις βαρντεναφίλης, οι οποίες διαλύονται ταχέως στο στόμα και οδηγούν σε μια αύξηση στη βιοδιαθεσιμότητα και σε μια καμπύλη συγκέντρωσης πλάσματος που μοιάζει με υψίπεδο, καθώς και μέθοδο για την παρασκευή τους.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005009240A DE102005009240A1 (de) | 2005-03-01 | 2005-03-01 | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
EP06706994A EP1858490B1 (de) | 2005-03-01 | 2006-02-16 | Arzneiformen mit verbesserten pharmakokinetischen eigenschaften |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1112874T1 true CY1112874T1 (el) | 2016-04-13 |
Family
ID=36264023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100558T CY1112874T1 (el) | 2005-03-01 | 2012-06-20 | Φαρμακευτικες μορφες με βελτιωμενες φαρμακοκινητικες ιδιοτητες |
Country Status (39)
Country | Link |
---|---|
US (2) | US8613950B2 (el) |
EP (2) | EP1858490B1 (el) |
JP (1) | JP5122984B2 (el) |
KR (1) | KR101360526B1 (el) |
CN (2) | CN101141950B (el) |
AR (2) | AR053552A1 (el) |
AT (1) | ATE552828T1 (el) |
AU (1) | AU2006220100B2 (el) |
BR (1) | BRPI0609375A2 (el) |
CA (1) | CA2599617C (el) |
CR (2) | CR9339A (el) |
CY (1) | CY1112874T1 (el) |
DE (1) | DE102005009240A1 (el) |
DK (1) | DK1858490T3 (el) |
DO (1) | DOP2006000049A (el) |
ES (1) | ES2384109T3 (el) |
GT (1) | GT200600097A (el) |
HK (1) | HK1118457A1 (el) |
HN (1) | HN2006009000A (el) |
HR (1) | HRP20120545T1 (el) |
IL (2) | IL185552A (el) |
MA (1) | MA29376B1 (el) |
MX (1) | MX2007010527A (el) |
MY (2) | MY148698A (el) |
NO (2) | NO332368B1 (el) |
NZ (1) | NZ561004A (el) |
PE (2) | PE20061015A1 (el) |
PL (1) | PL1858490T3 (el) |
PT (1) | PT1858490E (el) |
RS (1) | RS52374B (el) |
RU (2) | RU2423970C2 (el) |
SG (1) | SG160330A1 (el) |
SI (1) | SI1858490T1 (el) |
TN (1) | TNSN07336A1 (el) |
TW (1) | TWI387465B (el) |
UA (1) | UA93200C2 (el) |
UY (1) | UY29395A1 (el) |
WO (1) | WO2006092207A1 (el) |
ZA (1) | ZA200707320B (el) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
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DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
DE102005009240A1 (de) | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
FR2906140B1 (fr) * | 2006-09-22 | 2008-12-05 | Philippe Perovitch | Forme galenique pour l'administration par voie trans-muqueuse de principes actifs |
DE102007027067A1 (de) | 2007-06-12 | 2008-12-18 | Ratiopharm Gmbh | Verfahren zur Herstellung eines Arzneimittels enthaltend Vardenafil Hydrochlorid Trihydrat |
DE102009020888A1 (de) | 2009-05-12 | 2010-11-18 | Ratiopharm Gmbh | Schmelztablette, enthaltend ein Vardenafil-Salz |
US8920839B2 (en) | 2009-05-20 | 2014-12-30 | Sumitomo Dainippon Pharma Co., Ltd. | Dry-coated orally-disintegrating tablet |
GB2497728A (en) | 2011-12-14 | 2013-06-26 | Londonpharma Ltd | Statin formulations for transmucosal delivery |
GB2497933B (en) * | 2011-12-21 | 2014-12-24 | Londonpharma Ltd | Drug delivery technology |
CN103372014B (zh) * | 2012-04-26 | 2015-10-21 | 齐鲁制药有限公司 | 一种能快速溶出、稳定的盐酸伐地那非口服固体制剂及其制备方法 |
CN102727455B (zh) * | 2012-07-03 | 2016-06-29 | 北京科信必成医药科技发展有限公司 | 一种他达那非口腔崩解片及其制备方法 |
US20160317542A1 (en) | 2013-12-09 | 2016-11-03 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
CN110193015A (zh) * | 2018-02-27 | 2019-09-03 | 广州朗圣药业有限公司 | 一种盐酸伐地那非口腔崩解片及其制备方法 |
CN108272765B (zh) * | 2018-04-26 | 2021-02-02 | 江西杏林白马药业股份有限公司 | 含盐酸伐地那非的药物组合物、口崩片及其制备、应用 |
SG11202010792TA (en) | 2018-05-02 | 2020-11-27 | Ferring Bv | Improved pharmaceutical formulations |
CN110840851A (zh) * | 2019-08-16 | 2020-02-28 | 天津仁卫生物医药科技有限公司 | 一种盐酸伐地那非口腔崩解片及其制备方法 |
IT201900020350A1 (it) | 2019-11-05 | 2021-05-05 | Alpex Pharma Sa | Formulazione orodispersibile di vardenafil |
JP2023513045A (ja) | 2020-01-31 | 2023-03-30 | ナノコピーア リミテッド ライアビリティ カンパニー | 非晶質ニロチニブ微粒子及びその使用 |
EP4142699A1 (en) | 2020-04-30 | 2023-03-08 | Nanocopoeia LLC | Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib |
CN114848603B (zh) * | 2022-04-25 | 2023-12-12 | 湖北菲瑞生物药业有限公司 | 一种伐地那非冻干闪释片及其制备工艺 |
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AU2005299490C1 (en) | 2004-10-21 | 2012-01-19 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
WO2006058250A2 (en) | 2004-11-24 | 2006-06-01 | Spi Pharma, Inc. | Orally disintegrating compositions |
DE102005009240A1 (de) | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
CA2612917A1 (en) | 2005-06-23 | 2007-01-04 | Schering Corporation | Rapidly absorbing oral formulations of pde5 inhibitors |
WO2007029376A1 (ja) | 2005-09-02 | 2007-03-15 | Fuji Chemical Industry Co., Ltd. | 口腔内速崩壊性錠剤 |
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2005
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2006
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