CY1112684T1 - 3-κυανοπυρρολιδινυλ-φαινυλ-οξαζολιδινονες ως αντιβακτηριδιακα μεσα - Google Patents

3-κυανοπυρρολιδινυλ-φαινυλ-οξαζολιδινονες ως αντιβακτηριδιακα μεσα

Info

Publication number
CY1112684T1
CY1112684T1 CY20121100363T CY121100363T CY1112684T1 CY 1112684 T1 CY1112684 T1 CY 1112684T1 CY 20121100363 T CY20121100363 T CY 20121100363T CY 121100363 T CY121100363 T CY 121100363T CY 1112684 T1 CY1112684 T1 CY 1112684T1
Authority
CY
Cyprus
Prior art keywords
cyanopyrrolidinyl
oxazolidinones
phenyl
antibacterial agents
formula
Prior art date
Application number
CY20121100363T
Other languages
English (en)
Inventor
Montserrat Cano
Albert Palomer
Antonio Guglietta
Original Assignee
Ferrer Internacional, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40010598&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112684(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Internacional, S.A. filed Critical Ferrer Internacional, S.A.
Publication of CY1112684T1 publication Critical patent/CY1112684T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Η εφεύρεση παρέχει νέες ενώσεις οξαζολιδινόνης του τύπου (Ι) όπου τα R1, R2, και R3 έχουν διάφορες έννοιες. Επίσης παρέχονται μέθοδοι παρασκευής, φαρμακευτικές συνθέσεις, και χρήσεις αυτών στην αγωγή βακτηριδιακών λοιμώξεων.
CY20121100363T 2008-07-01 2012-04-12 3-κυανοπυρρολιδινυλ-φαινυλ-οξαζολιδινονες ως αντιβακτηριδιακα μεσα CY1112684T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08159446A EP2141161A1 (en) 2008-07-01 2008-07-01 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents
EP09772403A EP2321306B1 (en) 2008-07-01 2009-06-29 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents

Publications (1)

Publication Number Publication Date
CY1112684T1 true CY1112684T1 (el) 2016-02-10

Family

ID=40010598

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20121100363T CY1112684T1 (el) 2008-07-01 2012-04-12 3-κυανοπυρρολιδινυλ-φαινυλ-οξαζολιδινονες ως αντιβακτηριδιακα μεσα

Country Status (23)

Country Link
US (1) US20110152333A1 (el)
EP (2) EP2141161A1 (el)
JP (1) JP2011526589A (el)
KR (1) KR20110036601A (el)
CN (1) CN102112471A (el)
AR (1) AR072389A1 (el)
AT (1) ATE541842T1 (el)
AU (1) AU2009265790A1 (el)
BR (1) BRPI0913842A2 (el)
CA (1) CA2729491A1 (el)
CL (2) CL2009001493A1 (el)
CY (1) CY1112684T1 (el)
DK (1) DK2321306T3 (el)
ES (1) ES2381155T3 (el)
MX (1) MX2011000141A (el)
PE (1) PE20110161A1 (el)
PL (1) PL2321306T3 (el)
PT (1) PT2321306E (el)
RU (1) RU2011103485A (el)
SI (1) SI2321306T1 (el)
TW (1) TW201006828A (el)
UY (1) UY31953A (el)
WO (1) WO2010000703A1 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101128029B1 (ko) 2010-03-08 2012-03-29 주식회사 레고켐 바이오사이언스 (ｒ)-3-(3-플루오로-4-(1-메틸-5,6-다이하이드로-1,2,4-트리아진-4(1ｈ)-일)페닐)-5-(치환된 메틸)옥사졸리딘-2-온 유도체의 제조방법
US9573910B2 (en) * 2013-11-08 2017-02-21 Lee Pharma Limited Oxazolidinone antibacterial compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
PT788498E (pt) * 1994-10-26 2002-02-28 Upjohn Co Compostos antimicrobianos de feniloxazolidinona
US7687627B2 (en) * 2003-09-08 2010-03-30 Wockhardt Limited Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy

Also Published As

Publication number Publication date
WO2010000703A1 (en) 2010-01-07
DK2321306T3 (da) 2012-04-10
EP2141161A1 (en) 2010-01-06
CN102112471A (zh) 2011-06-29
BRPI0913842A2 (pt) 2015-10-20
TW201006828A (en) 2010-02-16
JP2011526589A (ja) 2011-10-13
CL2009001493A1 (es) 2009-12-11
SI2321306T1 (sl) 2012-05-31
UY31953A (es) 2010-01-29
ATE541842T1 (de) 2012-02-15
RU2011103485A (ru) 2012-08-10
CL2010001589A1 (es) 2011-11-11
PE20110161A1 (es) 2011-03-15
EP2321306B1 (en) 2012-01-18
US20110152333A1 (en) 2011-06-23
EP2321306A1 (en) 2011-05-18
MX2011000141A (es) 2011-04-05
PT2321306E (pt) 2012-04-13
KR20110036601A (ko) 2011-04-07
ES2381155T3 (es) 2012-05-23
AR072389A1 (es) 2010-08-25
PL2321306T3 (pl) 2012-06-29
CA2729491A1 (en) 2010-01-07
AU2009265790A1 (en) 2010-01-07

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