AR072389A1 - Compuesto de 3-cianopirrolidinil-fenil-oxazolidinona, procedimiento para prepararlo, composicion farmaceutica que la comprende y sus usos - Google Patents

Compuesto de 3-cianopirrolidinil-fenil-oxazolidinona, procedimiento para prepararlo, composicion farmaceutica que la comprende y sus usos

Info

Publication number
AR072389A1
AR072389A1 ARP090102398A ARP090102398A AR072389A1 AR 072389 A1 AR072389 A1 AR 072389A1 AR P090102398 A ARP090102398 A AR P090102398A AR P090102398 A ARP090102398 A AR P090102398A AR 072389 A1 AR072389 A1 AR 072389A1
Authority
AR
Argentina
Prior art keywords
oxazolidinona
cyanopirrolidinil
fenil
prepare
composite
Prior art date
Application number
ARP090102398A
Other languages
English (en)
Inventor
Biosca Montserrat Cano
Antonio Guglietta
Benet Albert Palomer
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40010598&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR072389(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of AR072389A1 publication Critical patent/AR072389A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

También se proporcionan procedimientos de preparacion, composiciones farmacéuticas y usos de los mismos para el tratamiento de infecciones bacterianas. Reivindicacion 1: Un compuesto de 3-cianopirrolidinil-fenil oxazolidinona, caracterizado porque es de formula (1), en forma libre o en forma de una sal farmacéuticamente aceptable, solvato, hidrato, o una forma enantiomérica, donde: R1 y R2 son radicales idénticos o diferentes y se seleccionan independientemente entre hidrogeno y fluor; R3 es un grupo alquilo C1-6 lineal o ramificado opcionalmente sustituido por un grupo seleccionado entre fluor, hidroxi y OR4; y R4 es un grupo alquilo C1-6 lineal o ramificado.
ARP090102398A 2008-07-01 2009-06-29 Compuesto de 3-cianopirrolidinil-fenil-oxazolidinona, procedimiento para prepararlo, composicion farmaceutica que la comprende y sus usos AR072389A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08159446A EP2141161A1 (en) 2008-07-01 2008-07-01 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents

Publications (1)

Publication Number Publication Date
AR072389A1 true AR072389A1 (es) 2010-08-25

Family

ID=40010598

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090102398A AR072389A1 (es) 2008-07-01 2009-06-29 Compuesto de 3-cianopirrolidinil-fenil-oxazolidinona, procedimiento para prepararlo, composicion farmaceutica que la comprende y sus usos

Country Status (23)

Country Link
US (1) US20110152333A1 (es)
EP (2) EP2141161A1 (es)
JP (1) JP2011526589A (es)
KR (1) KR20110036601A (es)
CN (1) CN102112471A (es)
AR (1) AR072389A1 (es)
AT (1) ATE541842T1 (es)
AU (1) AU2009265790A1 (es)
BR (1) BRPI0913842A2 (es)
CA (1) CA2729491A1 (es)
CL (2) CL2009001493A1 (es)
CY (1) CY1112684T1 (es)
DK (1) DK2321306T3 (es)
ES (1) ES2381155T3 (es)
MX (1) MX2011000141A (es)
PE (1) PE20110161A1 (es)
PL (1) PL2321306T3 (es)
PT (1) PT2321306E (es)
RU (1) RU2011103485A (es)
SI (1) SI2321306T1 (es)
TW (1) TW201006828A (es)
UY (1) UY31953A (es)
WO (1) WO2010000703A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101128029B1 (ko) 2010-03-08 2012-03-29 주식회사 레고켐 바이오사이언스 (ｒ)-3-(3-플루오로-4-(1-메틸-5,6-다이하이드로-1,2,4-트리아진-4(1ｈ)-일)페닐)-5-(치환된 메틸)옥사졸리딘-2-온 유도체의 제조방법
US9573910B2 (en) * 2013-11-08 2017-02-21 Lee Pharma Limited Oxazolidinone antibacterial compound

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688792A (en) 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
EP0788498B1 (en) * 1994-10-26 2001-08-16 PHARMACIA & UPJOHN COMPANY Phenyloxazolidinone antimicrobials
US7687627B2 (en) * 2003-09-08 2010-03-30 Wockhardt Limited Substituted piperidino phenyloxazolidinones having antimicrobial activity with improved in vivo efficacy

Also Published As

Publication number Publication date
JP2011526589A (ja) 2011-10-13
EP2141161A1 (en) 2010-01-06
UY31953A (es) 2010-01-29
RU2011103485A (ru) 2012-08-10
MX2011000141A (es) 2011-04-05
ATE541842T1 (de) 2012-02-15
ES2381155T3 (es) 2012-05-23
BRPI0913842A2 (pt) 2015-10-20
PL2321306T3 (pl) 2012-06-29
CL2009001493A1 (es) 2009-12-11
DK2321306T3 (da) 2012-04-10
EP2321306A1 (en) 2011-05-18
US20110152333A1 (en) 2011-06-23
EP2321306B1 (en) 2012-01-18
CN102112471A (zh) 2011-06-29
PT2321306E (pt) 2012-04-13
CA2729491A1 (en) 2010-01-07
AU2009265790A1 (en) 2010-01-07
SI2321306T1 (sl) 2012-05-31
WO2010000703A1 (en) 2010-01-07
CL2010001589A1 (es) 2011-11-11
TW201006828A (en) 2010-02-16
CY1112684T1 (el) 2016-02-10
PE20110161A1 (es) 2011-03-15
KR20110036601A (ko) 2011-04-07

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