CY1111805T1 - Υποκατεστημενες κινολονες ιιι - Google Patents
Υποκατεστημενες κινολονες ιιιInfo
- Publication number
- CY1111805T1 CY1111805T1 CY20111100842T CY111100842T CY1111805T1 CY 1111805 T1 CY1111805 T1 CY 1111805T1 CY 20111100842 T CY20111100842 T CY 20111100842T CY 111100842 T CY111100842 T CY 111100842T CY 1111805 T1 CY1111805 T1 CY 1111805T1
- Authority
- CY
- Cyprus
- Prior art keywords
- substituted
- cylinders iii
- diseases
- cylinders
- iii
- Prior art date
Links
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 241000701022 Cytomegalovirus Species 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000007660 quinolones Chemical class 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Η εφεύρεση αφορά υποκατεστημένες κινολόνες και μέθοδο για την παρασκευή τους, καθώς και τη χρήση τους για την παραγωγή φαρμακευτικών προϊόντων για τη θεραπεία νόσων και/ή την προφύλαξη από νόσους, ιδιαιτέρως για χρήση ως αντιικών παραγόντων, ιδιαιτέρως κατά του κυτταρομεγαλοϊού.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006005861A DE102006005861A1 (de) | 2006-02-09 | 2006-02-09 | Substituierte Chinolone III |
| EP07711438A EP1994020B1 (de) | 2006-02-09 | 2007-02-02 | Substituierte Chinolone III |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111805T1 true CY1111805T1 (el) | 2015-10-07 |
Family
ID=38283107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111100842T CY1111805T1 (el) | 2006-02-09 | 2011-08-31 | Υποκατεστημενες κινολονες ιιι |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7977349B2 (el) |
| EP (1) | EP1994020B1 (el) |
| JP (1) | JP5198291B2 (el) |
| KR (1) | KR101400568B1 (el) |
| CN (1) | CN101379055B (el) |
| AR (1) | AR059417A1 (el) |
| AT (1) | ATE513826T1 (el) |
| AU (1) | AU2007214006B2 (el) |
| BR (1) | BRPI0706988A2 (el) |
| CA (1) | CA2637204C (el) |
| CY (1) | CY1111805T1 (el) |
| DE (1) | DE102006005861A1 (el) |
| DK (1) | DK1994020T3 (el) |
| DO (1) | DOP2007000027A (el) |
| ES (1) | ES2366970T3 (el) |
| HK (1) | HK1125372A1 (el) |
| IL (1) | IL192662A (el) |
| MY (1) | MY151590A (el) |
| PE (1) | PE20080113A1 (el) |
| PL (1) | PL1994020T3 (el) |
| PT (1) | PT1994020E (el) |
| RU (1) | RU2433125C2 (el) |
| SI (1) | SI1994020T1 (el) |
| TW (1) | TWI382980B (el) |
| UA (1) | UA94934C2 (el) |
| UY (1) | UY30135A1 (el) |
| WO (1) | WO2007090579A2 (el) |
| ZA (1) | ZA200806355B (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR059339A1 (es) * | 2006-02-09 | 2008-03-26 | Chugai Pharmaceutical Co Ltd | Derivados de la cumarina para trastornos proliferativos de celulas, composicion farmaceutica y agente terapeutico que los contiene |
| TW200811153A (en) | 2006-06-23 | 2008-03-01 | Japan Tobacco Inc | 6-(heterocyclyl-substituted benzyl)-4-oxoquinoline compound and use thereof as HIV integrase inhibitor |
| DE102011101446A1 (de) * | 2011-05-10 | 2012-11-15 | Aicuris Gmbh & Co. Kg | Herstellung von "Dense Bodies" (DB) |
| WO2018110669A1 (en) | 2016-12-15 | 2018-06-21 | Ono Pharmaceutical Co., Ltd. | Activator of trek (twik related k+ channels) channels |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB932487A (en) | 1960-07-25 | 1963-07-31 | D G Searle & Co | Piperidine derivatives |
| DE3420743A1 (de) | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | 7-amino-1-cyclopropyl-6,8-dihalogen-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| CN1019114B (zh) | 1986-03-31 | 1992-11-18 | 三共株式会社 | 喹啉-3-羟酸衍生物的制备方法 |
| DE3702393A1 (de) * | 1987-01-28 | 1988-08-11 | Bayer Ag | 8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel |
| AU618823B2 (en) | 1988-07-20 | 1992-01-09 | Sankyo Company Limited | 4-oxoquinoline-3-carboxylic acid derivatives, their preparation and their use |
| US4959363A (en) | 1989-06-23 | 1990-09-25 | Sterling Drug Inc. | Quinolonecarboxamide compounds, their preparation and use as antivirals. |
| DE4303657A1 (de) | 1993-02-09 | 1994-08-11 | Bayer Ag | Neue Chinolon- und Naphthyridoncarbonsäurederivate |
| FR2713116B1 (fr) | 1993-11-30 | 1996-01-12 | Techmetal Promotion | Dispositif d'alimentation pour le dépôt par simple gravité d'un matériau granuleux sur la surface d'un métal liquide coulé en continu. |
| KR960004339A (ko) | 1994-07-02 | 1996-02-23 | 임성기 | 신규한 퀴놀린계 화합물 및 그 의 제조방법 |
| CA2225555A1 (en) | 1995-08-02 | 1997-02-13 | Chiroscience Limited | Quinolones and their therapeutic use |
| WO1997004779A1 (en) | 1995-08-02 | 1997-02-13 | Chiroscience Limited | Quinolones and their therapeutic use |
| US6248739B1 (en) * | 1999-01-08 | 2001-06-19 | Pharmacia & Upjohn Company | Quinolinecarboxamides as antiviral agents |
| DE19937024A1 (de) | 1999-08-05 | 2001-02-08 | Bayer Ag | Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker |
| US6525049B2 (en) * | 2000-07-05 | 2003-02-25 | Pharmacia & Upjohn Company | Pyrroloquinolones as antiviral agents |
| AU2001280091A1 (en) | 2000-08-01 | 2002-02-13 | Wockhardt Limited | Inhibitors of cellular efflux pumps of microbes |
| GB0023918D0 (en) | 2000-09-29 | 2000-11-15 | King S College London | Antiparasitic compounds |
| US6964966B2 (en) * | 2001-04-25 | 2005-11-15 | Wockhardt Limited | Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
| AR037097A1 (es) | 2001-10-05 | 2004-10-20 | Novartis Ag | Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento |
| AU2002361493A1 (en) | 2001-12-13 | 2003-06-23 | Wockhardt Limited | New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments |
| KR100944600B1 (ko) | 2003-04-07 | 2010-02-25 | 사일린 파마슈티칼스, 인크 | 치환된 퀴노벤족사진 유사체 |
| WO2005049602A1 (en) * | 2003-11-18 | 2005-06-02 | Warner-Lambert Company Llc | Quinolone antibacterial agents |
| DE102004035203A1 (de) * | 2004-07-21 | 2006-02-16 | Bayer Healthcare Ag | Substituierte Chinolone |
| DE102005030524A1 (de) | 2005-06-30 | 2007-01-18 | Aicuris Gmbh & Co. Kg | Substituierte Chinolone II |
-
2006
- 2006-02-09 DE DE102006005861A patent/DE102006005861A1/de not_active Ceased
-
2007
- 2007-01-23 MY MYPI20070105 patent/MY151590A/en unknown
- 2007-02-02 KR KR1020087021888A patent/KR101400568B1/ko active IP Right Grant
- 2007-02-02 SI SI200730702T patent/SI1994020T1/sl unknown
- 2007-02-02 DK DK07711438.7T patent/DK1994020T3/da active
- 2007-02-02 AT AT07711438T patent/ATE513826T1/de active
- 2007-02-02 WO PCT/EP2007/000923 patent/WO2007090579A2/de active Application Filing
- 2007-02-02 ES ES07711438T patent/ES2366970T3/es active Active
- 2007-02-02 PL PL07711438T patent/PL1994020T3/pl unknown
- 2007-02-02 UA UAA200810891A patent/UA94934C2/uk unknown
- 2007-02-02 AU AU2007214006A patent/AU2007214006B2/en not_active Ceased
- 2007-02-02 CA CA2637204A patent/CA2637204C/en not_active Expired - Fee Related
- 2007-02-02 CN CN2007800049872A patent/CN101379055B/zh not_active Expired - Fee Related
- 2007-02-02 ZA ZA200806355A patent/ZA200806355B/xx unknown
- 2007-02-02 PT PT07711438T patent/PT1994020E/pt unknown
- 2007-02-02 BR BRPI0706988-0A patent/BRPI0706988A2/pt active Search and Examination
- 2007-02-02 JP JP2008553660A patent/JP5198291B2/ja not_active Expired - Fee Related
- 2007-02-02 EP EP07711438A patent/EP1994020B1/de active Active
- 2007-02-02 RU RU2008136079/04A patent/RU2433125C2/ru not_active IP Right Cessation
- 2007-02-06 DO DO2007000027A patent/DOP2007000027A/es unknown
- 2007-02-07 UY UY30135A patent/UY30135A1/es not_active Application Discontinuation
- 2007-02-08 TW TW096104540A patent/TWI382980B/zh not_active IP Right Cessation
- 2007-02-08 PE PE2007000136A patent/PE20080113A1/es active IP Right Grant
- 2007-02-09 AR ARP070100546A patent/AR059417A1/es unknown
-
2008
- 2008-07-07 IL IL192662A patent/IL192662A/en not_active IP Right Cessation
- 2008-08-08 US US12/188,940 patent/US7977349B2/en not_active Expired - Fee Related
-
2009
- 2009-05-05 HK HK09104157.2A patent/HK1125372A1/xx not_active IP Right Cessation
-
2011
- 2011-08-31 CY CY20111100842T patent/CY1111805T1/el unknown
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