CY1111571T1 - Εισπνευσιμη αζτρεοναμη για τη θεραπεια και την προληψη πνευμονικων βακτηριακων λοιμωξεων - Google Patents
Εισπνευσιμη αζτρεοναμη για τη θεραπεια και την προληψη πνευμονικων βακτηριακων λοιμωξεωνInfo
- Publication number
- CY1111571T1 CY1111571T1 CY20111100581T CY111100581T CY1111571T1 CY 1111571 T1 CY1111571 T1 CY 1111571T1 CY 20111100581 T CY20111100581 T CY 20111100581T CY 111100581 T CY111100581 T CY 111100581T CY 1111571 T1 CY1111571 T1 CY 1111571T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- bacterial infections
- azroneonam
- inhalated
- prevention
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 2
- 230000002685 pulmonary effect Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 241001673062 Achromobacter xylosoxidans Species 0.000 abstract 1
- WZPBZJONDBGPKJ-UHFFFAOYSA-N Antibiotic SQ 26917 Natural products O=C1N(S(O)(=O)=O)C(C)C1NC(=O)C(=NOC(C)(C)C(O)=O)C1=CSC(N)=N1 WZPBZJONDBGPKJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000589513 Burkholderia cepacia Species 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 241000606768 Haemophilus influenzae Species 0.000 abstract 1
- 241000588749 Klebsiella oxytoca Species 0.000 abstract 1
- 241000588747 Klebsiella pneumoniae Species 0.000 abstract 1
- 241000122973 Stenotrophomonas maltophilia Species 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 abstract 1
- 229960003644 aztreonam Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25842300P | 2000-12-27 | 2000-12-27 | |
| EP01991523A EP1353647B1 (en) | 2000-12-27 | 2001-12-20 | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1111571T1 true CY1111571T1 (el) | 2014-04-09 |
Family
ID=22980480
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20111100581T CY1111571T1 (el) | 2000-12-27 | 2011-06-16 | Εισπνευσιμη αζτρεοναμη για τη θεραπεια και την προληψη πνευμονικων βακτηριακων λοιμωξεων |
| CY2011012C CY2011012I1 (el) | 2000-12-27 | 2011-08-22 | Εισπνευσιμη αζτρεοναμη για τη θεραπεια και την προληψη πνευμονικων βακτηριακων λοιμωξεων |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY2011012C CY2011012I1 (el) | 2000-12-27 | 2011-08-22 | Εισπνευσιμη αζτρεοναμη για τη θεραπεια και την προληψη πνευμονικων βακτηριακων λοιμωξεων |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US6660249B2 (enExample) |
| EP (2) | EP2301524B1 (enExample) |
| JP (1) | JP4646489B2 (enExample) |
| AT (1) | ATE502623T1 (enExample) |
| AU (1) | AU2002231244B2 (enExample) |
| BE (1) | BE2011C029I2 (enExample) |
| BR (1) | BRPI0116757B8 (enExample) |
| CA (2) | CA2433280C (enExample) |
| CY (2) | CY1111571T1 (enExample) |
| DE (2) | DE60144291D1 (enExample) |
| DK (2) | DK2301524T3 (enExample) |
| ES (2) | ES2406405T3 (enExample) |
| FR (1) | FR11C0030I2 (enExample) |
| IL (3) | IL156596A0 (enExample) |
| LU (1) | LU91851I2 (enExample) |
| NL (1) | NL300492I2 (enExample) |
| NO (3) | NO329643B1 (enExample) |
| PT (2) | PT2301524E (enExample) |
| WO (1) | WO2002051356A2 (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7214364B2 (en) | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| DK2301524T3 (da) | 2000-12-27 | 2013-07-15 | Gilead Sciences Inc | Inhalerbar aztreonam uden arginin til behandling og forebyggelse af bakterielle lungeinfektioner |
| US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
| US20030133925A1 (en) * | 2001-09-28 | 2003-07-17 | Shawar Ribhi M. | Monobactam compositions and methods of use thereof |
| AU2003230600B2 (en) * | 2002-03-05 | 2009-06-04 | Transave, Inc. | An inhalation system for prevention and treatment of intracellular infections |
| US7607436B2 (en) | 2002-05-06 | 2009-10-27 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| MXPA05001486A (es) | 2002-08-05 | 2006-05-25 | Teva Gyogyszergyar Reszvenytar | Preparacion de aztreonam. |
| WO2004052333A1 (en) * | 2002-12-11 | 2004-06-24 | Pari Gmbh | Pharmaceutical compositions for the pulmonary delivery of aztreonam |
| JP2006522634A (ja) * | 2003-04-14 | 2006-10-05 | ベクトゥラ・リミテッド | 投与効率を向上させるデバイス及び製薬組成 |
| US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
| US20040204439A1 (en) * | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
| US7452991B2 (en) | 2003-05-15 | 2008-11-18 | Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Aztreonam β polymorph with very low residual solvent content |
| WO2004103478A1 (en) * | 2003-05-20 | 2004-12-02 | Collins James F | Ophthalmic drug delivery system |
| BRPI0411691A (pt) * | 2003-07-02 | 2006-12-26 | Teva Gyogyszergyar Reszvenytar | l-lisina de aztreonam e seus métodos de preparação |
| AU2014271333B2 (en) * | 2003-07-03 | 2016-10-27 | Gilead Sciences, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| AU2004257632C1 (en) * | 2003-07-03 | 2010-04-15 | Gilead Sciences, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
| US7452523B2 (en) * | 2004-01-27 | 2008-11-18 | Gilead Sciences, Inc. | Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough and tussive attacks |
| US20050207983A1 (en) * | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
| GB0425758D0 (en) | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
| US20060210483A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections |
| WO2006122253A1 (en) | 2005-05-09 | 2006-11-16 | Sicor, Inc. | Process for making aztreonam |
| US20080107723A1 (en) * | 2006-09-28 | 2008-05-08 | Perkins Walter R | Methods of Treating Pulmonary Distress |
| HUP0700007A2 (en) * | 2007-01-08 | 2008-10-28 | Asthma Rehabilitacios Ct Kft | Device and process for producing of natrium chloride aerosol for the disorders of the respiratory system |
| CN101715349B (zh) * | 2007-05-08 | 2012-07-18 | 美国Rq生物科技有限公司 | 治疗革兰氏阴性细菌感染的治疗组合物及方法 |
| GB0714134D0 (en) * | 2007-07-19 | 2007-08-29 | Norton Healthcare Ltd | Dry-powder medicament |
| WO2009045706A1 (en) * | 2007-10-01 | 2009-04-09 | Gilead Sciences, Inc. | Inhaled aztreonam lysine for the treatment of deficits in health-related quality-of life in lung diseases |
| RU2527894C2 (ru) * | 2007-11-27 | 2014-09-10 | Альгифарма ИПР АС | Использование альгинатных олигомеров в борьбе с биопленками |
| EP2098219A1 (en) | 2008-03-05 | 2009-09-09 | PARI Pharma GmbH | Macrolide compositions having improved taste and stability |
| US20090271021A1 (en) * | 2008-04-28 | 2009-10-29 | Popp Shane M | Execution system for the monitoring and execution of insulin manufacture |
| JP5671001B2 (ja) | 2009-03-26 | 2015-02-18 | パルマトリックス，インコーポレイテッド | 肺疾患を治療するための乾燥粉末製剤および方法 |
| RU2582938C2 (ru) * | 2009-06-03 | 2016-04-27 | АльгиФарма АС | Альгинатные олигомеры для применения в преодолении множественной лекарственной устойчивости у бактерий |
| US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
| WO2012030664A1 (en) | 2010-08-30 | 2012-03-08 | Pulmatrix, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| US20120076859A1 (en) * | 2010-09-23 | 2012-03-29 | Activaero Gmbh | Targeted Lung Delivery of Citrulline and/or Another Nitric Oxide Precursor and a Method for Treatment of Pulmonary Deficiency of Nitric Oxide in Cystic Fibrosis and Other Pulmonary Diseases |
| EP4008326A1 (en) | 2010-09-29 | 2022-06-08 | Pulmatrix Operating Company, Inc. | Monovalent metal cation dry powders for inhalation |
| PT2621488T (pt) | 2010-09-29 | 2019-02-12 | Pulmatrix Operating Co Inc | Pós secos catiónicos |
| EP2804589A1 (en) * | 2012-01-16 | 2014-11-26 | Mahmut Bilgic | Pharmaceutical formulations comprising aztreonam |
| US20150136130A1 (en) | 2012-02-29 | 2015-05-21 | Pulmatrix, Inc. | Inhalable dry powders |
| EP2978434A4 (en) * | 2013-03-28 | 2016-08-17 | Pharmacaribe Llc | COMPOSITIONS, FORMULATIONS AND METHODS FOR BIO-ALIGNING THE PH-VALUE OF A STERILE ISOTONIC SALT SOLUTION AND HYPERTONIC SALT SOLUTIONS |
| KR20150135328A (ko) | 2013-04-01 | 2015-12-02 | 풀매트릭스 인코퍼레이티드 | 티오트로피움 건조 분말 |
| CN104784159A (zh) * | 2015-04-15 | 2015-07-22 | 苏州惠仁生物科技有限公司 | 氨曲南粉雾剂的制备方法 |
| KR102295739B1 (ko) | 2016-05-03 | 2021-08-30 | 뉴마 레스퍼러토리 인코포레이티드 | 유체들의 폐기관계로의 전달을 위한 액적 전달 디바이스 및 사용 방법 |
| US11285274B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device |
| WO2017192773A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency |
| WO2017192782A1 (en) * | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
| EP4624054A3 (en) | 2016-05-03 | 2025-11-19 | Pneuma Respiratory, Inc. | Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device |
| WO2018213834A1 (en) | 2017-05-19 | 2018-11-22 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
| KR102643190B1 (ko) | 2017-06-10 | 2024-03-04 | 아이노비아 인코포레이티드 | 유체를 취급하기 위한, 그리고 눈에 유체를 전달하기 위한 디바이스들 |
| CN118203735A (zh) | 2017-10-04 | 2024-06-18 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
| EP3697481B1 (en) | 2017-10-17 | 2024-05-22 | Pneuma Respiratory, Inc. | Nasal drug delivery apparatus and methods of use |
| CA3082192A1 (en) | 2017-11-08 | 2019-05-16 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use |
| CN110898040B (zh) * | 2018-09-18 | 2022-05-17 | 北京盈科瑞创新药物研究有限公司 | 一种吸入用氨曲南溶液用冻干粉及其制备方法 |
| US12208061B2 (en) * | 2019-02-28 | 2025-01-28 | Exorao Life Science S.R.L. | Sterile aztreonam package |
| US12691236B2 (en) | 2019-05-09 | 2026-07-28 | Pneuma Respiratory, Inc. | Ultrasonic breath actuated respiratory droplet delivery device and methods of use |
| CN114206421A (zh) | 2019-06-27 | 2022-03-18 | 精呼吸股份有限公司 | 小液滴经由电子呼吸致动液滴输送装置到呼吸系统的输送 |
| WO2021119513A1 (en) | 2019-12-11 | 2021-06-17 | Eyenovia, Inc. | Systems and devices for delivering fluids to the eye and methods of use |
| CN111647537B (zh) * | 2020-06-18 | 2022-04-26 | 浙江工业大学 | 一种耐盐辣椒素降解菌、应用及餐厨垃圾处理方法 |
| WO2022271848A1 (en) | 2021-06-22 | 2022-12-29 | Pneuma Respiratory, Inc. | Droplet delivery device with push ejection |
| CN119768202A (zh) | 2022-07-18 | 2025-04-04 | 精呼吸股份有限公司 | 小步长高分辨率气溶胶生成系统及方法 |
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2001
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- 2001-12-20 JP JP2002552504A patent/JP4646489B2/ja not_active Expired - Lifetime
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- 2001-12-20 WO PCT/US2001/050062 patent/WO2002051356A2/en not_active Ceased
- 2001-12-20 US US10/027,113 patent/US6660249B2/en not_active Expired - Lifetime
- 2001-12-20 ES ES10010411T patent/ES2406405T3/es not_active Expired - Lifetime
- 2001-12-20 DE DE60144291T patent/DE60144291D1/de not_active Expired - Lifetime
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- 2001-12-20 DE DE201112100043 patent/DE122011100043I1/de active Pending
- 2001-12-20 AT AT01991523T patent/ATE502623T1/de active
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- 2001-12-20 EP EP10010411.6A patent/EP2301524B1/en not_active Revoked
- 2001-12-20 AU AU2002231244A patent/AU2002231244B2/en not_active Expired
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- 2003-06-23 IL IL156596A patent/IL156596A/en active Protection Beyond IP Right Term
- 2003-06-26 NO NO20032946A patent/NO329643B1/no not_active IP Right Cessation
- 2003-09-04 US US10/654,815 patent/US7208141B2/en not_active Expired - Lifetime
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