NO20101377L - Aztreonamblanding og anvendelse derav - Google Patents
Aztreonamblanding og anvendelse deravInfo
- Publication number
- NO20101377L NO20101377L NO20101377A NO20101377A NO20101377L NO 20101377 L NO20101377 L NO 20101377L NO 20101377 A NO20101377 A NO 20101377A NO 20101377 A NO20101377 A NO 20101377A NO 20101377 L NO20101377 L NO 20101377L
- Authority
- NO
- Norway
- Prior art keywords
- delivered
- pseudomonas aeruginosa
- proteus mirabilis
- infections caused
- aztreone
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 241000588770 Proteus mirabilis Species 0.000 abstract 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 241001673062 Achromobacter xylosoxidans Species 0.000 abstract 1
- WZPBZJONDBGPKJ-UHFFFAOYSA-N Antibiotic SQ 26917 Natural products O=C1N(S(O)(=O)=O)C(C)C1NC(=O)C(=NOC(C)(C)C(O)=O)C1=CSC(N)=N1 WZPBZJONDBGPKJ-UHFFFAOYSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241000589513 Burkholderia cepacia Species 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 241000606768 Haemophilus influenzae Species 0.000 abstract 1
- 241000588749 Klebsiella oxytoca Species 0.000 abstract 1
- 241000588747 Klebsiella pneumoniae Species 0.000 abstract 1
- 241000122973 Stenotrophomonas maltophilia Species 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 abstract 1
- 229960003644 aztreonam Drugs 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
Det beskrives en fremgangsmåte og en blanding for behandling av pulmonale bakterieinfeksjoner forårsaket av gramnegative bakterier, og som er egnet for behandling av infeksjoner forårsaket av Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter-arter, Serratia marcescens, så vel som de som forårsakes av Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans og multimedikamentresistent Pseudomonas aeruginosa, ved å benytte en konsentrert formulering av aztreonam, eller et farmasøytisk akseptabelt salt derav, avlevert som en aerosol- eller tørrpulverformulering.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25842300P | 2000-12-27 | 2000-12-27 | |
PCT/US2001/050062 WO2002051356A2 (en) | 2000-12-27 | 2001-12-20 | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20101377L true NO20101377L (no) | 2003-08-26 |
Family
ID=22980480
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20032946A NO329643B1 (no) | 2000-12-27 | 2003-06-26 | Aztreonamblanding og anvendelse derav |
NO20101377A NO20101377L (no) | 2000-12-27 | 2010-10-05 | Aztreonamblanding og anvendelse derav |
NO2011001C NO2011001I2 (no) | 2000-12-27 | 2011-01-25 | Aztreonam eller et farmasøytisk akseptabelt salt derav som ikke er et argininsalt |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20032946A NO329643B1 (no) | 2000-12-27 | 2003-06-26 | Aztreonamblanding og anvendelse derav |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO2011001C NO2011001I2 (no) | 2000-12-27 | 2011-01-25 | Aztreonam eller et farmasøytisk akseptabelt salt derav som ikke er et argininsalt |
Country Status (19)
Country | Link |
---|---|
US (6) | US6660249B2 (no) |
EP (2) | EP1353647B1 (no) |
JP (1) | JP4646489B2 (no) |
AT (1) | ATE502623T1 (no) |
AU (1) | AU2002231244B2 (no) |
BE (1) | BE2011C029I2 (no) |
BR (1) | BRPI0116757B8 (no) |
CA (2) | CA2433280C (no) |
CY (2) | CY1111571T1 (no) |
DE (2) | DE122011100043I1 (no) |
DK (2) | DK2301524T3 (no) |
ES (2) | ES2360692T3 (no) |
FR (1) | FR11C0030I2 (no) |
IL (3) | IL156596A0 (no) |
LU (1) | LU91851I2 (no) |
NL (1) | NL300492I2 (no) |
NO (3) | NO329643B1 (no) |
PT (2) | PT1353647E (no) |
WO (1) | WO2002051356A2 (no) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7214364B2 (en) * | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
EP1353647B1 (en) | 2000-12-27 | 2011-03-23 | Gilead Sciences, Inc. | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
US20030133925A1 (en) * | 2001-09-28 | 2003-07-17 | Shawar Ribhi M. | Monobactam compositions and methods of use thereof |
JP2005530704A (ja) * | 2002-03-05 | 2005-10-13 | トランセイブ, インク. | 細胞内感染を予防及び治療するための吸入システム |
US7607436B2 (en) | 2002-05-06 | 2009-10-27 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
CN1681812A (zh) | 2002-08-05 | 2005-10-12 | 特瓦药厂有限公司 | 氨曲南的制备 |
AU2002356646A1 (en) * | 2002-12-11 | 2004-06-30 | Pari Gmbh | Pharmaceutical compositions for the pulmonary delivery of aztreonam |
US20060147389A1 (en) * | 2004-04-14 | 2006-07-06 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
CA2522158C (en) * | 2003-04-14 | 2018-03-20 | Vectura Ltd. | Devices and pharmaceutical compositions for enhancing dosing efficiency |
US20040204439A1 (en) * | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
CN1802371A (zh) | 2003-05-15 | 2006-07-12 | 特瓦药厂有限公司 | 残余溶剂含量极低的阿兹托南β多晶型 |
EP1624938B1 (en) * | 2003-05-20 | 2011-03-16 | James F. Collins | Ophthalmic drug delivery system |
CA2733145C (en) * | 2003-07-02 | 2012-06-19 | Corus Pharma, Inc. | Aztreonam l-lysine and method of determining impurities therein |
AU2014271333B2 (en) * | 2003-07-03 | 2016-10-27 | Gilead Sciences, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
AU2004257632C1 (en) * | 2003-07-03 | 2010-04-15 | Gilead Sciences, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
US7452523B2 (en) * | 2004-01-27 | 2008-11-18 | Gilead Sciences, Inc. | Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough and tussive attacks |
US20050207983A1 (en) * | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
GB0425758D0 (en) | 2004-11-23 | 2004-12-22 | Vectura Ltd | Preparation of pharmaceutical compositions |
US20060210483A1 (en) * | 2005-03-02 | 2006-09-21 | Kodsi Robert E | Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections |
DE602006005240D1 (de) | 2005-05-09 | 2009-04-02 | Sicor Inc | Herstellungsverfahren für aztreonam |
US20080107723A1 (en) * | 2006-09-28 | 2008-05-08 | Perkins Walter R | Methods of Treating Pulmonary Distress |
HUP0700007A2 (en) * | 2007-01-08 | 2008-10-28 | Asthma Rehabilitacios Ct Kft | Device and process for producing of natrium chloride aerosol for the disorders of the respiratory system |
EP2155251B1 (en) * | 2007-05-08 | 2013-09-25 | Rq Bioscience, Inc. | Therapeutic compositions and methods for treating gram-negative bacterial infections |
GB0714134D0 (en) * | 2007-07-19 | 2007-08-29 | Norton Healthcare Ltd | Dry-powder medicament |
AR068514A1 (es) * | 2007-10-01 | 2009-11-18 | Gilead Sciences Inc | Aztreonam lisina inhalada para el tratamiento de deficits de salud relacionados con la calidad de vida (cvrs) de las enfermedades pulmonares |
CN104189908B (zh) | 2007-11-27 | 2017-01-11 | 阿尔吉法玛公司 | 包含藻酸盐低聚物的产品、包含无生命表面的产品和清创组合物 |
EP2098219A1 (en) | 2008-03-05 | 2009-09-09 | PARI Pharma GmbH | Macrolide compositions having improved taste and stability |
US20090271021A1 (en) * | 2008-04-28 | 2009-10-29 | Popp Shane M | Execution system for the monitoring and execution of insulin manufacture |
AU2010229668C1 (en) | 2009-03-26 | 2016-09-15 | Pulmatrix Operating Co., Inc. | Dry powder formulations and methods for treating pulmonary diseases |
US9018158B2 (en) | 2009-06-03 | 2015-04-28 | Algipharma As | Alginate oligomers for use in overcoming multidrug resistance in bacteria |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
JP5877201B2 (ja) | 2010-08-30 | 2016-03-02 | パルマトリックス,インコーポレイテッド | 肺疾患を治療するための乾燥粉末製剤および方法 |
US20120076859A1 (en) * | 2010-09-23 | 2012-03-29 | Activaero Gmbh | Targeted Lung Delivery of Citrulline and/or Another Nitric Oxide Precursor and a Method for Treatment of Pulmonary Deficiency of Nitric Oxide in Cystic Fibrosis and Other Pulmonary Diseases |
CA2812414C (en) | 2010-09-29 | 2020-09-22 | Pulmatrix, Inc. | Monovalent metal cation dry powders for inhalation |
DK2621488T3 (en) | 2010-09-29 | 2019-03-04 | Pulmatrix Operating Co Inc | CATIONIC DRY POWDER |
WO2013109217A1 (en) * | 2012-01-16 | 2013-07-25 | Mahmut Bilgic | Pharmaceutical formulations comprising aztreonam |
CN107596518B (zh) | 2012-02-29 | 2021-04-23 | 普马特里克斯营业公司 | 可吸入干粉剂 |
CA2910825A1 (en) * | 2013-03-28 | 2014-10-02 | Pharmacaribe, Llc | Compositions, formulations and methods of bio-balancing the ph of sterile isotonic saline and hypertonic saline solutions |
CN105324106A (zh) | 2013-04-01 | 2016-02-10 | 普马特里克斯营业公司 | 噻托铵干粉 |
CN104784159A (zh) * | 2015-04-15 | 2015-07-22 | 苏州惠仁生物科技有限公司 | 氨曲南粉雾剂的制备方法 |
JP2019523109A (ja) | 2016-05-03 | 2019-08-22 | ニューマ・リスパイラトリー・インコーポレイテッド | 肺健康管理のためのシステムおよび方法 |
WO2018213834A1 (en) | 2017-05-19 | 2018-11-22 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
KR102643190B1 (ko) | 2017-06-10 | 2024-03-04 | 아이노비아 인코포레이티드 | 유체를 취급하기 위한, 그리고 눈에 유체를 전달하기 위한 디바이스들 |
CN111526914A (zh) | 2017-10-04 | 2020-08-11 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
CA3079189A1 (en) | 2017-10-17 | 2019-04-25 | Pneuma Respiratory, Inc. | Nasal drug delivery apparatus and methods of use |
US11771852B2 (en) | 2017-11-08 | 2023-10-03 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use |
CN110898040B (zh) * | 2018-09-18 | 2022-05-17 | 北京盈科瑞创新药物研究有限公司 | 一种吸入用氨曲南溶液用冻干粉及其制备方法 |
US20220142866A1 (en) * | 2019-02-28 | 2022-05-12 | Exorao Life Science S.R.L. | Sterile aztreonam package |
CN111647537B (zh) * | 2020-06-18 | 2022-04-26 | 浙江工业大学 | 一种耐盐辣椒素降解菌、应用及餐厨垃圾处理方法 |
KR20240037245A (ko) | 2021-06-22 | 2024-03-21 | 뉴마 레스퍼러토리 인코포레이티드 | 푸시 이젝션에 의한 액적 전달 장치 |
Family Cites Families (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US572801A (en) * | 1896-12-08 | Telephone-exchange | ||
US9126A (en) * | 1852-07-13 | Marcus r | ||
US610824A (en) * | 1898-09-13 | Sleigh attachment for vehicles | ||
US673739A (en) * | 1900-09-19 | 1901-05-07 | Frank B Stearns | Driving mechanism for vehicles. |
US775670A (en) * | 1904-08-17 | 1904-11-22 | Thomas F Whittelsey | Air-brake safety device. |
US946838A (en) * | 1909-08-17 | 1910-01-18 | George Dawson | Tempering compound. |
US4775670A (en) | 1980-09-29 | 1988-10-04 | E. R. Squibb & Sons, Inc. | 2-oxo-1-azetidinesulfonic acid salts |
WO1982001873A1 (en) * | 1980-12-05 | 1982-06-10 | Takeda Chemical Industries Ltd | 1-sulfo-2-oxoazetidine derivatives and process for their preparation |
US4673739A (en) | 1980-12-05 | 1987-06-16 | Takeda Chemical Industries, Ltd. | 4-carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production |
US4529698A (en) * | 1981-01-19 | 1985-07-16 | E. R. Squibb & Sons, Inc. | Process for preparing a 2-oxo-1-azetidinesulfonic acid salt |
US4625022A (en) * | 1981-02-02 | 1986-11-25 | E. R. Squibb & Sons, Inc. | Process for preparing (s)-3-amino-2-oxo-1-azetidinesulfonic acid salts |
US4386034A (en) * | 1981-02-02 | 1983-05-31 | E. R. Squibb & Sons, Inc. | Sulfamated amino acid amides |
US4572801A (en) | 1981-04-30 | 1986-02-25 | Takeda Chemical Industries, Ltd. | 4-Carbamoyloxymethyl-1-sulfo-2-oxoazetidine derivatives and their production |
US4946838A (en) | 1981-07-13 | 1990-08-07 | E. R. Squibb & Sons, Inc. | Crystalline anhydrous aztreonam |
CA1181075A (en) | 1981-07-13 | 1985-01-15 | David M. Floyd | CRYSTALLINE ANHYDROUS FORM OF [3-S-[3.alpha.(Z),4 .beta.]]-3-[[(2-AMINO-4-THIAZOLYL) [(1-CARBOXY-1-METHYLETHOXY)IMINO]ACETYL] AMINO]-4-METHYL-2-OXO-1-AZETIDINESULFONIC ACID |
US4752469A (en) * | 1984-01-09 | 1988-06-21 | E. R. Squibb & Sons, Inc. | Potentiators of beta-lactam antibiotics |
US4826973A (en) * | 1984-07-20 | 1989-05-02 | E. R. Squibb & Sons, Inc. | Delta form of aztreonam and preparation thereof |
US4610824A (en) | 1984-10-09 | 1986-09-09 | E. R. Squibb & Sons, Inc. | Hydrazide derivatives of monocyclic beta-lactam antibiotics |
US4888998A (en) * | 1986-07-11 | 1989-12-26 | Beckman Instruments, Inc. | Sample handling system |
CA1339136C (en) | 1987-07-01 | 1997-07-29 | Sailesh Amilal Varia | Amorphous form of aztreonam |
US5194604A (en) * | 1990-06-29 | 1993-03-16 | E. R. Squibb & Sons, Inc. | Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains |
IL104068A (en) * | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant |
CA2105629A1 (en) * | 1992-09-14 | 1994-03-15 | Robert S. Becker | Potentiation of immunogenic response |
DK0754050T3 (da) * | 1994-01-14 | 2002-10-21 | Xoma Technology Ltd | Anti-gram-positive bakterielle fremgangsmåder og materialer |
US5508269A (en) | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
US5662929A (en) * | 1994-12-23 | 1997-09-02 | Universite De Montreal | Therapeutic liposomal formulation |
US5723495A (en) | 1995-11-16 | 1998-03-03 | The University Of North Carolina At Chapel Hill | Benzamidoxime prodrugs as antipneumocystic agents |
US5875776A (en) * | 1996-04-09 | 1999-03-02 | Vivorx Pharmaceuticals, Inc. | Dry powder inhaler |
US6180604B1 (en) | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
EP0970966B1 (en) | 1996-09-04 | 2008-02-20 | Takara Bio Inc. | Fungal antigens and process for producing the same |
US5994340A (en) * | 1997-08-29 | 1999-11-30 | Synphar Laboratories, Inc. | Azetidinone derivatives as β-lactamase inhibitors |
CA2410694A1 (en) | 1998-06-16 | 1999-12-16 | Serge Dea | Porcine reproductive and respiratory syndrome virus (prrsv) dna vaccines |
CA2514899A1 (en) | 1998-08-31 | 2000-03-09 | Biogen, Inc. | Method of modulating memory effector t-cells and compositions |
US6387886B1 (en) * | 1998-12-17 | 2002-05-14 | Chiron Corporation | Method for the treatment of severe chronic bronchitis (bronchietasis) with an aerosolized antibiotic |
AU782493B2 (en) | 1999-06-01 | 2005-08-04 | Curis, Inc. | Polymer conjugates of hedgehog proteins and uses |
US6576224B1 (en) * | 1999-07-06 | 2003-06-10 | Sinuspharma, Inc. | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis |
DK1223915T3 (da) * | 1999-10-29 | 2006-03-06 | Nektar Therapeutics | Törpulverpræparater med forbedret dispersivitet |
DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
US7138419B2 (en) * | 2000-12-27 | 2006-11-21 | Corus Pharma, Inc. | Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate |
EP1353647B1 (en) | 2000-12-27 | 2011-03-23 | Gilead Sciences, Inc. | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
US7214364B2 (en) * | 2000-12-27 | 2007-05-08 | Corus Pharma, Inc. | Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections |
WO2003031163A2 (en) * | 2001-10-08 | 2003-04-17 | California Institute Of Technology | Microfabricated lenses, methods of manufacture thereof, and applications therefor |
MXPA04003879A (es) | 2001-10-24 | 2005-02-17 | Pari Gmbh | Equipo para la preparacion de una composicion farmaceutica. |
JP2005530704A (ja) | 2002-03-05 | 2005-10-13 | トランセイブ, インク. | 細胞内感染を予防及び治療するための吸入システム |
EP1417958A1 (en) | 2002-11-08 | 2004-05-12 | Pari GmbH | Wet granulation process |
AU2002356646A1 (en) | 2002-12-11 | 2004-06-30 | Pari Gmbh | Pharmaceutical compositions for the pulmonary delivery of aztreonam |
CA2733145C (en) | 2003-07-02 | 2012-06-19 | Corus Pharma, Inc. | Aztreonam l-lysine and method of determining impurities therein |
AR068514A1 (es) | 2007-10-01 | 2009-11-18 | Gilead Sciences Inc | Aztreonam lisina inhalada para el tratamiento de deficits de salud relacionados con la calidad de vida (cvrs) de las enfermedades pulmonares |
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