JP2019523109A - 肺健康管理のためのシステムおよび方法 - Google Patents
肺健康管理のためのシステムおよび方法 Download PDFInfo
- Publication number
- JP2019523109A JP2019523109A JP2019510564A JP2019510564A JP2019523109A JP 2019523109 A JP2019523109 A JP 2019523109A JP 2019510564 A JP2019510564 A JP 2019510564A JP 2019510564 A JP2019510564 A JP 2019510564A JP 2019523109 A JP2019523109 A JP 2019523109A
- Authority
- JP
- Japan
- Prior art keywords
- air
- inhalation
- patient
- lung
- inhalation device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004072 lung Anatomy 0.000 title claims abstract description 96
- 230000036541 health Effects 0.000 title claims abstract description 70
- 238000000034 method Methods 0.000 title claims abstract description 67
- 238000005085 air analysis Methods 0.000 claims abstract description 37
- 239000003570 air Substances 0.000 claims description 124
- 239000000443 aerosol Substances 0.000 claims description 52
- 230000007613 environmental effect Effects 0.000 claims description 24
- 230000002685 pulmonary effect Effects 0.000 claims description 21
- 238000005259 measurement Methods 0.000 claims description 20
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 15
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims description 14
- 201000010099 disease Diseases 0.000 claims description 14
- 230000003434 inspiratory effect Effects 0.000 claims description 13
- 238000004458 analytical method Methods 0.000 claims description 12
- 238000012795 verification Methods 0.000 claims description 12
- 238000003745 diagnosis Methods 0.000 claims description 10
- 239000007921 spray Substances 0.000 claims description 10
- 238000011282 treatment Methods 0.000 claims description 9
- 239000012298 atmosphere Substances 0.000 claims description 6
- 238000012790 confirmation Methods 0.000 claims description 6
- 230000002596 correlated effect Effects 0.000 claims description 6
- 239000012080 ambient air Substances 0.000 claims description 5
- 230000000875 corresponding effect Effects 0.000 claims description 4
- 238000005507 spraying Methods 0.000 claims description 3
- 238000011144 upstream manufacturing Methods 0.000 claims description 2
- 239000000356 contaminant Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 description 80
- 229940079593 drug Drugs 0.000 description 79
- 239000012530 fluid Substances 0.000 description 40
- 238000012384 transportation and delivery Methods 0.000 description 33
- 238000004891 communication Methods 0.000 description 19
- 239000002245 particle Substances 0.000 description 19
- 238000010586 diagram Methods 0.000 description 17
- 238000007726 management method Methods 0.000 description 17
- 230000029058 respiratory gaseous exchange Effects 0.000 description 16
- 230000008859 change Effects 0.000 description 15
- 238000000151 deposition Methods 0.000 description 15
- 230000010355 oscillation Effects 0.000 description 15
- 238000013500 data storage Methods 0.000 description 14
- 230000008021 deposition Effects 0.000 description 14
- 238000012377 drug delivery Methods 0.000 description 14
- 238000012544 monitoring process Methods 0.000 description 14
- 238000002663 nebulization Methods 0.000 description 12
- 230000000241 respiratory effect Effects 0.000 description 12
- 208000006673 asthma Diseases 0.000 description 11
- 238000013461 design Methods 0.000 description 9
- 238000003860 storage Methods 0.000 description 8
- 230000000694 effects Effects 0.000 description 7
- 230000033001 locomotion Effects 0.000 description 7
- 238000012545 processing Methods 0.000 description 7
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 6
- 230000000739 chaotic effect Effects 0.000 description 6
- 230000004199 lung function Effects 0.000 description 6
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 5
- 238000001514 detection method Methods 0.000 description 5
- 230000007246 mechanism Effects 0.000 description 5
- 238000002483 medication Methods 0.000 description 5
- 239000012528 membrane Substances 0.000 description 5
- 210000000214 mouth Anatomy 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- 238000012383 pulmonary drug delivery Methods 0.000 description 5
- 239000012855 volatile organic compound Substances 0.000 description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
- 230000001133 acceleration Effects 0.000 description 4
- 238000007792 addition Methods 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000002651 drug therapy Methods 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 230000007704 transition Effects 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 238000002835 absorbance Methods 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 239000000090 biomarker Substances 0.000 description 3
- 230000004397 blinking Effects 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 238000004590 computer program Methods 0.000 description 3
- 230000006866 deterioration Effects 0.000 description 3
- 238000006073 displacement reaction Methods 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 230000007170 pathology Effects 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 230000002829 reductive effect Effects 0.000 description 3
- 230000005236 sound signal Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000003075 superhydrophobic effect Effects 0.000 description 3
- 206010006326 Breath odour Diseases 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- -1 H 2 S Chemical compound 0.000 description 2
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 208000011623 Obstructive Lung disease Diseases 0.000 description 2
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 2
- 206010062237 Renal impairment Diseases 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 238000003915 air pollution Methods 0.000 description 2
- 229910021529 ammonia Inorganic materials 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 206010012601 diabetes mellitus Diseases 0.000 description 2
- 230000009977 dual effect Effects 0.000 description 2
- 238000013399 early diagnosis Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 230000005977 kidney dysfunction Effects 0.000 description 2
- 150000002605 large molecules Chemical class 0.000 description 2
- 201000005202 lung cancer Diseases 0.000 description 2
- 208000020816 lung neoplasm Diseases 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 description 2
- 230000000414 obstructive effect Effects 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 208000023504 respiratory system disease Diseases 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000011664 signaling Effects 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000008685 targeting Effects 0.000 description 2
- 238000012549 training Methods 0.000 description 2
- 230000001960 triggered effect Effects 0.000 description 2
- 238000013024 troubleshooting Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 description 1
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 description 1
- 208000000884 Airway Obstruction Diseases 0.000 description 1
- 208000037874 Asthma exacerbation Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000034423 Delivery Diseases 0.000 description 1
- 206010014561 Emphysema Diseases 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 208000030934 Restrictive pulmonary disease Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000009798 acute exacerbation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000000809 air pollutant Substances 0.000 description 1
- 231100001243 air pollutant Toxicity 0.000 description 1
- 239000013566 allergen Substances 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 210000003123 bronchiole Anatomy 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 239000004566 building material Substances 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000012159 carrier gas Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000001351 cycling effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000000890 drug combination Substances 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 230000008278 dynamic mechanism Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000009503 electrostatic coating Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 230000003090 exacerbative effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000002847 impedance measurement Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 239000008263 liquid aerosol Substances 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 239000008249 pharmaceutical aerosol Substances 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 239000003380 propellant Substances 0.000 description 1
- 208000005069 pulmonary fibrosis Diseases 0.000 description 1
- 230000009325 pulmonary function Effects 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000011897 real-time detection Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 230000008054 signal transmission Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000013403 standard screening design Methods 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
- 208000037804 stenosis Diseases 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000010897 surface acoustic wave method Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000012385 systemic delivery Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 238000010200 validation analysis Methods 0.000 description 1
- 244000052613 viral pathogen Species 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/087—Measuring breath flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/003—Particle size control by passing the aerosol trough sieves or filters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
- A61M15/0081—Locking means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
- A61M15/025—Bubble jet droplet ejection devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0051—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes with alarm devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0057—Pumps therefor
- A61M16/0066—Blowers or centrifugal pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/105—Filters
- A61M16/106—Filters in a path
- A61M16/107—Filters in a path in the inspiratory path
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1075—Preparation of respiratory gases or vapours by influencing the temperature
- A61M16/108—Preparation of respiratory gases or vapours by influencing the temperature before being humidified or mixed with a beneficial agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
- A61M16/142—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase with semi-permeable walls separating the liquid from the respiratory gas
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0638—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers spray being produced by discharging the liquid or other fluent material through a plate comprising a plurality of orifices
- B05B17/0646—Vibrating plates, i.e. plates being directly subjected to the vibrations, e.g. having a piezoelectric transducer attached thereto
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/13—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
- G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
- G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/0816—Measuring devices for examining respiratory frequency
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
- A61B5/091—Measuring volume of inspired or expired gases, e.g. to determine lung capacity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
- A61M16/022—Control means therefor
- A61M16/024—Control means therefor including calculation means, e.g. using a processor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/1075—Preparation of respiratory gases or vapours by influencing the temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0027—Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0036—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the breathing tube and used in both inspiratory and expiratory phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
- A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
- A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0233—Conductive materials, e.g. antistatic coatings for spark prevention
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0238—General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0272—Electro-active or magneto-active materials
- A61M2205/0294—Piezoelectric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
- A61M2205/103—General characteristics of the apparatus with powered movement mechanisms rotating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/27—General characteristics of the apparatus preventing use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/27—General characteristics of the apparatus preventing use
- A61M2205/276—General characteristics of the apparatus preventing use preventing unwanted use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
- A61M2205/3313—Optical measuring means used specific wavelengths
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3327—Measuring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3553—Range remote, e.g. between patient's home and doctor's office
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3546—Range
- A61M2205/3569—Range sublocal, e.g. between console and disposable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
- A61M2205/3584—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using modem, internet or bluetooth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/35—Communication
- A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
- A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/502—User interfaces, e.g. screens or keyboards
- A61M2205/505—Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
- A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/587—Lighting arrangements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6063—Optical identification systems
- A61M2205/6072—Bar codes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7536—General characteristics of the apparatus with filters allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/11—Laminar flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
- A61M2230/06—Heartbeat rate only
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/205—Blood composition characteristics partial oxygen pressure (P-O2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/30—Blood pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B7/00—Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas
- B05B7/0012—Apparatus for achieving spraying before discharge from the apparatus
Abstract
Description
[0001]本出願は、2016年5月3日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/331,328号と、2016年5月5日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/332,352号と、2016年5月10日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/334,076号と、2016年6月24日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/354,437号と、2016年9月23日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/399,091号と、2016年11月1日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/416,026号と、2016年11月16日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/422,932号と、2016年12月1日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/428,696号と、2017年1月20日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/448,796号と、2017年3月15日出願の「DISPOSABLE PULMONARY DRUG DELIVERY APPARATUS AND METHODS OF USE(使い捨て肺薬剤送達装置および使用方法)」という名称の米国仮特許出願第62/471,929号との米国特許法第119条に基づく利益を主張する。各出願の内容は、その全体が参照により本明細書に組み込まれる。
口腔圧力P1bについて 流量Fb=(P2−P1b)/R
[00117]これらの条件における流量および圧力は、気道抵抗についての値を下記によって直接計算するために使用され得る。
[00118]これは、気道抵抗と肺胞圧力の両方が、呼吸サイクルの間の肺および気道ジオメトリの変化とともに著しく変化するので、2つの口腔圧力間の比較的迅速な遷移を仮定することに留意されたい。圧力の迅速な遷移によって、2つの圧力の間のほぼ一定の肺胞圧力の仮定は、真である。空気および流れ抵抗のコンプライアンスは、ローパスフィルタが高周波信号を最小化するほど、変動を効果的に除去するので、圧力がどれくらい迅速に変動させられ得るかには限界がある。
R=(P1c−P1d)/(P1c/Rc−P1d/Rd)を生じる。
R=(P1c−P1d)/(P1c/Rc−P1d/KRc) またはR=(1/Rc)*(P1c−P1d)/(P1c−P1d/K)になる。
[00124]空気分析器402は、肺コンプライアンスに関する追加の空気分析を生成し得、異なるサイクル時間を用いた上記の2圧力試験を行うことによって、気道抵抗の位置が評価され得る。この場合、2つの異なる圧力間でサイクルする代わりに、吸入デバイス100における流れ抵抗は、線形信号処理の仮定に近似するように正弦曲線として変動させられる。
[00147]図9A〜図9Cを参照すると、一実装形態では、吸入デバイス100は、ハンドル900と、マウスピース904を囲むハウジング902と、使い捨てまたは再利用可能カートリッジ908を受けるためのカートリッジマウント906と、層流要素910と、マウスピース904によって画定される開口912とを含む。
圧力範囲; +/−500Pa範囲;周囲に対するデルタP測定値
絶対精度; 3%またはより良好
再現性; 3%またはより良好
FS分解能; 1%またはより良好
デジタルまたはアナログ出力; デジタルが選好される;I2CまたはSPI
電源電圧; 3VDC+/−5%
オフセット、自動ゼロ化; オンになった後;
保管温度: −20〜+60C;
動作温度: 10〜45C;
[00154]センサーアセンブリ914は、低差動圧力における感度、オフセットドリフト、およびヒステリシスに関して、従来の圧電抵抗膜センサーよりも優れ得る。これらの性能パラメータは、低い圧力における増加した分解能およびより正確な測定値を可能にする。これらの性能パラメータは、低い肺出力をもつ子供および高齢患者にとって特に重要である。
Claims (22)
- 肺健康管理のための方法であって、前記方法は、
ネットワークを介して1つまたは複数の吸入デバイスから肺健康管理情報を受信するステップであって、前記1つまたは複数の吸入デバイスの各々が、前記吸入デバイスの管を通る空気流の流量を測定する1つまたは複数の圧力センサーを有する、受信するステップと、
前記1つまたは複数の吸入デバイスが配備された1つまたは複数の地理的ロケーションについての環境データを受信するステップであって、前記環境データが、1つまたは複数の環境センサーを使用してキャプチャされ、かつ前記1つまたは複数の地理的ロケーションの各々の周囲空気状態に対応する、受信するステップと、
少なくとも1つのコンピューティングユニットを使用して、少なくとも1つの管理パラメータに基づいて、前記肺健康管理情報を前記環境データと相関させるステップと、
前記少なくとも1つのコンピューティングユニットを使用して、前記相関させられたデータから空気分析を生成するステップと
を含む、方法。 - ユーザデバイス上の表示のために前記空気分析を出力するステップをさらに含む、請求項1に記載の方法。
- 前記ユーザデバイスが、患者デバイスまたは提供者デバイスのうちの少なくとも1つである、請求項2に記載の方法。
- 前記少なくとも1つの管理パラメータが、疾患タイプ、患者プロファイル、噴霧検証タイプ、環境状態タイプ、デバイスエラータイプ、または汚染物質タイプのうちの少なくとも1つを含む、請求項1に記載の方法。
- 前記空気分析が、空気品質分析、疾患分析、ヘルスケア分析、デバイス分析、アラート、または傾向のうちの少なくとも1つを含む、請求項1に記載の方法。
- 患者のための肺健康管理のための方法であって、前記方法は、
前記患者によって吸入の間に達成されたピーク吸気流測定値を受信するステップであって、前記ピーク吸気流測定値が、前記吸入の間の空気流の最小圧力に基づいて生成される、受信するステップと、
前記患者についての肺出力を受信するステップであって、前記肺出力が、呼息の間に達成された最大流を測定することによって決定される、受信するステップと、
少なくとも1つのコンピューティングユニットを使用して、前記患者についての肺健康管理情報を生成するステップであって、前記肺健康管理情報が、前記ピーク吸気流測定値と前記肺出力とに基づいて生成される肺健康プロファイルを含む、生成するステップと、
前記肺健康管理情報を出力するステップと
を含む、方法。 - 前記肺健康プロファイルがさらに、前記呼息中の一酸化窒素の濃度値に基づいて生成される、請求項6に記載の方法。
- 前記肺健康管理情報が、ユーザデバイスを用いた提示のために出力される、請求項6に記載の方法。
- 前記肺健康プロファイルがさらに、気道抵抗に基づいて生成される、請求項6に記載の方法。
- 前記肺健康管理情報が、ユーザデバイスによってネットワークを介して空気分析器に通信される、請求項6に記載の方法。
- 経時的な前記肺健康管理情報の変化を追跡するステップをさらに含む、請求項6に記載の方法。
- 前記肺健康プロファイルが、肺状態の診断または前記肺状態のための処置のうちの少なくとも1つを含む、請求項6に記載の方法。
- 患者のための肺健康管理のための方法であって、前記方法は、
前記患者による吸入サイクルの開始を識別するステップと、
1つまたは複数の圧力センサーを使用して空気流の流量を測定することによって、前記吸入サイクルにおけるトリガポイントを決定するステップと、
エアロゾルプルームを前記空気流に噴霧するステップと、
エジェクタアセンブリを使用して、前記トリガポイントにおいて前記エアロゾルプルーム(plume)中への液滴(droplets)のセット(set)の放出を自動的に生成するステップと、
液滴の前記セットの前記放出を確認するステップと
を含む、方法。 - 前記1つまたは複数の圧力センサーが、前記空気流中の上流に配設された第1のセンサーと、前記空気流の外部に配設された第2のセンサーとを含み、前記第1のセンサーが内圧を測定し、前記第2のセンサーが外圧を測定し、前記流量が、前記内圧と前記外圧との間の圧力差から測定される、請求項13に記載の方法。
- 前記流量が、前記空気流と周囲大気との間の圧力低下に基づいて測定される、請求項13に記載の方法。
- 液滴の前記セットが、各々が5ミクロン以下のサイズを有する1つまたは複数の液滴を含む、請求項13に記載の方法。
- 前記トリガポイントが、前記吸入サイクルにおけるピークに対応する、請求項13に記載の方法。
- 液滴の前記セットの前記放出が、前記エアロゾルプルーム中の放出質量の速度を検出することによって確認される、請求項13に記載の方法。
- 液滴の前記セットの前記放出が、前記エアロゾルプルームの横断面および長さを検出することによって確認される、請求項13に記載の方法。
- 前記トリガポイントがあらかじめ設定される、請求項13に記載の方法。
- ユーザデバイスを使用して、確認情報を空気分析器に通信するステップであって、前記確認情報が、液滴の前記セットの前記放出の前記確認に基づいて生成される、通信するステップをさらに含む、請求項13に記載の方法。
- 前記確認情報に基づいてフィードバックを生成するステップをさらに含む、請求項21に記載の方法。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2021083714A JP2021130013A (ja) | 2016-05-03 | 2021-05-18 | 肺健康管理のためのシステムおよび方法 |
Applications Claiming Priority (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662331328P | 2016-05-03 | 2016-05-03 | |
US62/331,328 | 2016-05-03 | ||
US201662332352P | 2016-05-05 | 2016-05-05 | |
US62/332,352 | 2016-05-05 | ||
US201662334076P | 2016-05-10 | 2016-05-10 | |
US62/334,076 | 2016-05-10 | ||
US201662354437P | 2016-06-24 | 2016-06-24 | |
US62/354,437 | 2016-06-24 | ||
US201662399091P | 2016-09-23 | 2016-09-23 | |
US62/399,091 | 2016-09-23 | ||
US201662416026P | 2016-11-01 | 2016-11-01 | |
US62/416,026 | 2016-11-01 | ||
US201662422932P | 2016-11-16 | 2016-11-16 | |
US62/422,932 | 2016-11-16 | ||
US201662428696P | 2016-12-01 | 2016-12-01 | |
US62/428,696 | 2016-12-01 | ||
US201762448796P | 2017-01-20 | 2017-01-20 | |
US62/448,796 | 2017-01-20 | ||
US201762471929P | 2017-03-15 | 2017-03-15 | |
US62/471,929 | 2017-03-15 | ||
PCT/US2017/030925 WO2017192778A1 (en) | 2016-05-03 | 2017-05-03 | Systems and methods for pulmonary health management |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021083714A Division JP2021130013A (ja) | 2016-05-03 | 2021-05-18 | 肺健康管理のためのシステムおよび方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2019523109A true JP2019523109A (ja) | 2019-08-22 |
Family
ID=60203296
Family Applications (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019510564A Pending JP2019523109A (ja) | 2016-05-03 | 2017-05-03 | 肺健康管理のためのシステムおよび方法 |
JP2019510563A Active JP7407593B2 (ja) | 2016-05-03 | 2017-05-03 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2018569173A Active JP6774508B2 (ja) | 2016-05-03 | 2017-05-03 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2019233651A Active JP7072554B2 (ja) | 2016-05-03 | 2019-12-25 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2021083714A Pending JP2021130013A (ja) | 2016-05-03 | 2021-05-18 | 肺健康管理のためのシステムおよび方法 |
JP2022165165A Pending JP2022188270A (ja) | 2016-05-03 | 2022-10-14 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2023067741A Pending JP2023093609A (ja) | 2016-05-03 | 2023-04-18 | 肺健康管理のためのシステムおよび方法 |
Family Applications After (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019510563A Active JP7407593B2 (ja) | 2016-05-03 | 2017-05-03 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2018569173A Active JP6774508B2 (ja) | 2016-05-03 | 2017-05-03 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2019233651A Active JP7072554B2 (ja) | 2016-05-03 | 2019-12-25 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2021083714A Pending JP2021130013A (ja) | 2016-05-03 | 2021-05-18 | 肺健康管理のためのシステムおよび方法 |
JP2022165165A Pending JP2022188270A (ja) | 2016-05-03 | 2022-10-14 | 流体を肺系に供給するための液滴送達装置、及びその使用方法 |
JP2023067741A Pending JP2023093609A (ja) | 2016-05-03 | 2023-04-18 | 肺健康管理のためのシステムおよび方法 |
Country Status (9)
Country | Link |
---|---|
US (13) | US11285285B2 (ja) |
EP (3) | EP3451905A4 (ja) |
JP (7) | JP2019523109A (ja) |
KR (2) | KR102295739B1 (ja) |
CN (3) | CN109475707A (ja) |
AU (3) | AU2017259982B2 (ja) |
CA (2) | CA3022918A1 (ja) |
IL (1) | IL262735B (ja) |
WO (6) | WO2017192778A1 (ja) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103379867B (zh) * | 2010-12-21 | 2016-10-19 | 史赛克公司 | 带有位于被密封外壳中的控制模块的电动手术工具,该外壳具有保护内部构件不受消毒操作影响的主动密封件 |
US11253661B2 (en) | 2012-06-25 | 2022-02-22 | Gecko Health Innovations, Inc. | Devices, systems, and methods for adherence monitoring and patient interaction |
ES2716907T3 (es) | 2013-08-28 | 2019-06-17 | Gecko Health Innovations Inc | Dispositivos para monitorizar el cumplimiento y dispositivos para monitorizar el uso de dispensadores de consumibles |
JP7000151B2 (ja) | 2014-08-28 | 2022-01-19 | ノートン (ウォーターフォード) リミテッド | 吸入器用のコンプライアンス監視モジュール |
KR102548643B1 (ko) | 2014-08-28 | 2023-06-27 | 노턴 (워터포드) 리미티드 | 흡입기용 순응 보조 모듈 |
BR112017003867A2 (pt) | 2014-08-28 | 2018-11-06 | Microdose Therapeutx Inc | inalador de pó seco com ativação do sensor miniaturizado de pressão |
SI3204095T1 (sl) * | 2014-10-10 | 2019-08-30 | Ablynx N.V. | Inhalacijska naprava za uporabo pri zdravljenju bolezni dihal z aerosolom |
GB201420039D0 (en) | 2014-11-11 | 2014-12-24 | Teva Uk Ltd | System for training a user in administering a medicament |
US10058661B2 (en) | 2014-12-04 | 2018-08-28 | Norton (Waterford) Limited | Inhalation monitoring system and method |
ES2654803T3 (es) * | 2015-08-03 | 2018-02-15 | Pari Pharma Gmbh | Método de fabricación de un cabezal vibratorio para un generador de aerosol y cabezal vibratorio para un generador de aerosol |
US11285285B2 (en) * | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
US20180071274A1 (en) * | 2016-06-06 | 2018-03-15 | Nicholas A. Havercroft | Medical product for reducing and/or eliminating symptoms of nicotine withdrawal |
US20170348495A1 (en) * | 2016-06-06 | 2017-12-07 | Nicholas A. Havercroft | Modified nebulizer, method and system for delivering pharmaceutical products to an individual |
CA3032761C (en) * | 2016-08-04 | 2022-06-07 | Japan Tobacco Inc. | Flavor inhaler with oscillator |
EP3506971B1 (en) | 2016-11-18 | 2020-07-29 | Norton (Waterford) Limited | Inhaler |
KR102539907B1 (ko) | 2016-11-18 | 2023-06-05 | 노턴 (워터포드) 리미티드 | 전자 장치를 구비한 약물 전달 기구 |
US11617840B2 (en) * | 2017-03-31 | 2023-04-04 | L'oreal | Systems, devices, and methods including varying viscosity cosmetic dispenser |
EP4223335A3 (en) | 2017-05-19 | 2023-11-08 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
US10786633B2 (en) * | 2017-09-08 | 2020-09-29 | Hcmed Innovations Co., Ltd. | Nebulizer and nozzle assembly thereof |
US11738158B2 (en) | 2017-10-04 | 2023-08-29 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device and methods of use |
EP3697481A4 (en) | 2017-10-17 | 2021-07-14 | Pneuma Respiratory, Inc. | NASAL DRUG DELIVERY DEVICE AND METHOD OF USE |
JP2021502178A (ja) | 2017-11-08 | 2021-01-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
CA3087769A1 (en) * | 2018-01-08 | 2019-07-11 | Pneuma Respiratory, Inc. | Treatment of pulmonary cancers using an electronic breath actuated droplet delivery device |
KR102466230B1 (ko) * | 2018-01-09 | 2022-11-10 | 다카시 다케하라 | 휴대식 가스 공급 장치 |
WO2019157208A1 (en) | 2018-02-08 | 2019-08-15 | Optimist Inhaler LLC | Security features for an electronic metered-dose inhaler system |
WO2019161065A1 (en) | 2018-02-16 | 2019-08-22 | University Of Louisville Research Foundation, Inc. | Respiratory training and airway pressure monitoring device |
US20210008305A1 (en) * | 2018-03-09 | 2021-01-14 | Health Research, Inc. | Induction spacer for inhaler |
GB201805257D0 (en) | 2018-03-29 | 2018-05-16 | Nicoventures Holdings Ltd | An aerosol delivery device, an article for use therewith, and a method of identifying an article |
WO2019195239A1 (en) * | 2018-04-02 | 2019-10-10 | Pneuma Respiratory, Inc. | Handheld digital nebulizer device and methods of use |
AU2019261425A1 (en) * | 2018-04-24 | 2020-10-29 | Mannkind Corporation | Apparatus, system and method for detecting and monitoring inhalations |
CA3103893A1 (en) * | 2018-06-15 | 2019-12-19 | Valley Product Concepts, LLC | Capsules for use in personal vaporizers |
WO2020003305A1 (en) * | 2018-06-26 | 2020-01-02 | Omega Life Science Ltd. | Aerosol generation devices |
DE102018212411A1 (de) * | 2018-07-25 | 2020-01-30 | Robert Bosch Gmbh | Verfahren zur Gewinnung einer Atemprobe eines Probanden und Vorrichtung |
CN111936124A (zh) * | 2018-07-26 | 2020-11-13 | 四川海思科制药有限公司 | 一种含格隆铵盐及茚达特罗盐的气雾剂药物组合物及其制备方法与应用 |
CN111971034A (zh) * | 2018-07-26 | 2020-11-20 | 四川海思科制药有限公司 | 一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用 |
US11690963B2 (en) | 2018-08-22 | 2023-07-04 | Qnovia, Inc. | Electronic device for producing an aerosol for inhalation by a person |
US11517685B2 (en) | 2019-01-18 | 2022-12-06 | Qnovia, Inc. | Electronic device for producing an aerosol for inhalation by a person |
JP7235277B2 (ja) * | 2018-08-30 | 2023-03-08 | 株式会社フクダ産業 | 鼻腔抵抗測定装置 |
EP3860768A4 (en) * | 2018-10-01 | 2022-06-29 | Pneuma Respiratory, Inc. | Delivery of low surface tension compositions to the pulmonary system via electronic breath actuated droplet delivery device |
USD863533S1 (en) | 2019-01-04 | 2019-10-15 | Optimist Inhaler LLC | Metered-dose inhaler |
USD863531S1 (en) | 2019-01-04 | 2019-10-15 | Optimist Inhaler LLC | Metered-dose inhaler mouthpiece |
USD863532S1 (en) | 2019-01-04 | 2019-10-15 | Optimist Inhaler LLC | Metered-dose inhaler pump unit |
US11419995B2 (en) * | 2019-04-30 | 2022-08-23 | Norton (Waterford) Limited | Inhaler system |
KR20220003584A (ko) * | 2019-04-30 | 2022-01-10 | 노턴 (워터포드) 리미티드 | 흡입기 시스템 |
JP2022532131A (ja) * | 2019-05-08 | 2022-07-13 | レスピノヴァ リミテッド | 吸入療法を送達するためのシステム |
US20220226587A1 (en) * | 2019-05-09 | 2022-07-21 | Pneuma Respiratory, Inc. | Ultrasonic breath actuated respiratory droplet delivery device and methods of use |
EP4036921A1 (en) | 2019-05-17 | 2022-08-03 | Norton (Waterford) Limited | Drug delivery device with electronics |
US11037666B1 (en) * | 2019-05-29 | 2021-06-15 | Bottomline Technologies, Inc. | Method and apparatus for detecting diverted drugs |
CN110064108B (zh) * | 2019-06-10 | 2021-01-12 | 河南科技大学第一附属医院 | 呼吸内科用雾化吸入系统 |
AU2020308104A1 (en) * | 2019-06-27 | 2022-02-03 | Pneuma Respiratory, Inc. | Delivery of small droplets to the respiratory system via electronic breath actuated droplet delivery device |
USD863534S1 (en) | 2019-07-01 | 2019-10-15 | Optimist Inhaler LLC | Flip-open metered-dose inhaler |
EP4007626B1 (en) | 2019-08-02 | 2023-09-13 | Stamford Devices Limited | Buccal administration of aerosol |
USD877322S1 (en) | 2019-08-03 | 2020-03-03 | Optimist Inhaler, LLC | Flip-top metered-dose inhaler |
CN110433366B (zh) * | 2019-08-12 | 2022-03-04 | 杭州市红十字会医院 | 一种便携式呼吸科给药器 |
US11889861B2 (en) | 2019-09-23 | 2024-02-06 | Rai Strategic Holdings, Inc. | Arrangement of atomization assemblies for aerosol delivery device |
HUP1900356A1 (hu) * | 2019-10-11 | 2021-04-28 | Spirocco Kft | Kétirányú térfogatáram mérõ eszköz MDI inhalácíós készülékhez, valamint MDI inhalációs készülék, mely ilyen kétirányú térfogatáram mérõ eszközt tartalmaz |
CN111297454B (zh) * | 2020-03-18 | 2021-03-16 | 韦志永 | 肿瘤科用的肿瘤摘取器 |
WO2021203038A1 (en) * | 2020-04-03 | 2021-10-07 | Pneuma Respiratory, Inc. | Delivery of ginsenosides to the respiratory system via electronic breath actuated droplet delivery device |
DE102020110258B4 (de) * | 2020-04-15 | 2021-10-28 | Hauni Maschinenbau Gmbh | Inhalator |
EP4167984A1 (en) | 2020-06-23 | 2023-04-26 | Flagship Pioneering, Inc. | Anti-viral compounds and methods of using same |
US10994083B1 (en) | 2020-10-02 | 2021-05-04 | Bahram Kam Habibi | Electronic inhaler |
CN116322848A (zh) | 2020-10-16 | 2023-06-23 | 维克多瑞传送设备有限公司 | 用于检测振动膜喷雾器中液体存在的方法 |
WO2022161938A1 (en) | 2021-01-28 | 2022-08-04 | Aurena Laboratories Holding Ab | An inhaler body with a mouthpiece |
US20220241525A1 (en) * | 2021-02-04 | 2022-08-04 | Funai Electric Co., Ltd. | Method for controlling fluid jet plume characteristics |
US20220241526A1 (en) * | 2021-02-04 | 2022-08-04 | Funai Electric Co., Ltd. | Method for controlling fluid jet plume characteristics |
WO2022192736A1 (en) * | 2021-03-12 | 2022-09-15 | Vyaire Medical, Inc. | Smart nebulizer system |
CN113133931B (zh) * | 2021-04-23 | 2023-06-02 | 河南科技大学第一附属医院 | 一种眼科护理用清洗器 |
WO2022246413A1 (en) * | 2021-05-18 | 2022-11-24 | Legacy US Inc. | Fluid mixing apparatus such as a ventilator |
WO2022263049A1 (en) * | 2021-06-16 | 2022-12-22 | Stamford Devices Limited | A ventilator system |
KR20240037245A (ko) | 2021-06-22 | 2024-03-21 | 뉴마 레스퍼러토리 인코포레이티드 | 푸시 이젝션에 의한 액적 전달 장치 |
WO2023281435A1 (en) | 2021-07-08 | 2023-01-12 | Jt International Sa | Top loading cartridge for an inkjet technology aerosol smoking system |
WO2023110407A1 (en) * | 2021-12-17 | 2023-06-22 | Stamford Devices Limited | A nebulizer with plume detection |
EP4197646A1 (en) * | 2021-12-17 | 2023-06-21 | Stamford Devices Limited | A nebulizer with plume detection |
WO2023130041A2 (en) * | 2021-12-29 | 2023-07-06 | Breatheasy Co., D/B/A Miist Therapeutics | Nicotine delivery systems |
US20230337735A1 (en) | 2022-04-22 | 2023-10-26 | Qnovia, Inc. | Electronic devices for aerosolizing and inhaling liquid |
US11850356B1 (en) * | 2023-06-08 | 2023-12-26 | Microneb Tech Holdings, Inc. | Apparatus, methods, and systems for administering a medication to a patient from a capsule using an atomizer |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020032387A1 (en) * | 1996-05-08 | 2002-03-14 | Jacob Geva | Apparatus and method for remote spirometry |
US20140213925A1 (en) * | 2011-09-20 | 2014-07-31 | Isonea Limited | Systems, methods and kits for measuring respiratory rate and dynamically predicting respiratory episodes |
Family Cites Families (204)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3934585A (en) | 1970-08-13 | 1976-01-27 | Maurice David M | Method and apparatus for application of eye drops |
DE2445791C2 (de) | 1974-09-25 | 1984-04-19 | Siemens AG, 1000 Berlin und 8000 München | Ultraschall-Flüssigkeitszerstäuber |
US5021701A (en) | 1988-10-20 | 1991-06-04 | Tdk Corporation | Piezoelectric vibrator mounting system for a nebulizer |
US5487378A (en) * | 1990-12-17 | 1996-01-30 | Minnesota Mining And Manufacturing Company | Inhaler |
US5404871A (en) | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
US5164740A (en) | 1991-04-24 | 1992-11-17 | Yehuda Ivri | High frequency printing mechanism |
US7628339B2 (en) | 1991-04-24 | 2009-12-08 | Novartis Pharma Ag | Systems and methods for controlling fluid feed to an aerosol generator |
US5938117A (en) | 1991-04-24 | 1999-08-17 | Aerogen, Inc. | Methods and apparatus for dispensing liquids as an atomized spray |
US5363842A (en) | 1991-12-20 | 1994-11-15 | Circadian, Inc. | Intelligent inhaler providing feedback to both patient and medical professional |
GB2272389B (en) | 1992-11-04 | 1996-07-24 | Bespak Plc | Dispensing apparatus |
US5888477A (en) | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
US5607410A (en) | 1993-02-16 | 1997-03-04 | Branch; John D. | Vision directed eye wash |
CN100566769C (zh) | 1993-06-29 | 2009-12-09 | 茵捷特数码浮质有限公司 | 利用吸入方式服用物质的方法和器具 |
ES2171455T3 (es) | 1993-06-29 | 2002-09-16 | Ponwell Entpr Ltd | Dispensador. |
GB9405952D0 (en) | 1994-03-25 | 1994-05-11 | Zeneca Ltd | Aqueous ophthalmic sprays |
US5522385A (en) | 1994-09-27 | 1996-06-04 | Aradigm Corporation | Dynamic particle size control for aerosolized drug delivery |
JPH10508248A (ja) | 1994-11-02 | 1998-08-18 | ダンミスト・アンパルドゼルスカブ | 液体霧化方法と装置 |
US6011062A (en) | 1994-12-22 | 2000-01-04 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
US5487738A (en) * | 1995-03-31 | 1996-01-30 | Sciulli; Eugene B. | Apparatus for drawing fluids into a hypodermic syringe |
US6085740A (en) | 1996-02-21 | 2000-07-11 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US5758637A (en) | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
US5586550A (en) | 1995-08-31 | 1996-12-24 | Fluid Propulsion Technologies, Inc. | Apparatus and methods for the delivery of therapeutic liquids to the respiratory system |
US20020121274A1 (en) | 1995-04-05 | 2002-09-05 | Aerogen, Inc. | Laminated electroformed aperture plate |
TR199701665T1 (xx) | 1995-06-21 | 1998-06-22 | Asta Med�Ca Aktingesellschaft | B�t�nle�ik �l�me cihaz�na sahip farmas�tik toz kartu�u ve toz halinde t�bbi maddeler i�in soluma cihaz�. |
US5828394A (en) | 1995-09-20 | 1998-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | Fluid drop ejector and method |
DE19535010C2 (de) | 1995-09-21 | 1998-01-22 | Pelikan Produktions Ag | Verwendung eines Tropfenerzeugers in einem medizinischen Gerät zum dosierten Zuführen eines Medikamentes zu einem Fluidstrom |
US5823179A (en) | 1996-02-13 | 1998-10-20 | 1263152 Ontario Inc. | Nebulizer apparatus and method |
US5997642A (en) * | 1996-05-21 | 1999-12-07 | Symetrix Corporation | Method and apparatus for misted deposition of integrated circuit quality thin films |
JP3557595B2 (ja) * | 1996-10-22 | 2004-08-25 | 日本光電工業株式会社 | フローセンサ |
US5906202A (en) | 1996-11-21 | 1999-05-25 | Aradigm Corporation | Device and method for directing aerosolized mist to a specific area of the respiratory tract |
JPH1142219A (ja) * | 1997-07-28 | 1999-02-16 | Omron Corp | 肺活量測定装置 |
DE1149602T1 (de) | 1997-11-19 | 2002-04-04 | Microflow Eng Sa | Sprühvorrichtung für einen für die Atemtherapie geeigneten Inhalator |
US6257234B1 (en) * | 1998-08-21 | 2001-07-10 | Respironics, Inc. | Apparatus and method for determining respiratory mechanics of a patient and for controlling a ventilator based thereon |
US6397838B1 (en) | 1998-12-23 | 2002-06-04 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary aerosol delivery device and method |
US6378780B1 (en) * | 1999-02-09 | 2002-04-30 | S. C. Johnson & Son, Inc. | Delivery system for dispensing volatiles |
US6196218B1 (en) | 1999-02-24 | 2001-03-06 | Ponwell Enterprises Ltd | Piezo inhaler |
US6615826B1 (en) | 1999-02-26 | 2003-09-09 | 3M Innovative Properties Company | Slow spray metered dose inhaler |
AU760096B2 (en) | 1999-03-08 | 2003-05-08 | S.C. Johnson & Son, Inc. | Improved attachment method for piezoelectric elements |
US6235177B1 (en) | 1999-09-09 | 2001-05-22 | Aerogen, Inc. | Method for the construction of an aperture plate for dispensing liquid droplets |
CO5270018A1 (es) | 1999-12-11 | 2003-04-30 | Glaxo Group Ltd | Distribuidor de medicamento |
WO2001058514A1 (en) | 2000-02-11 | 2001-08-16 | Profile Respiratory Systems Limited | Drug delivery apparatus |
MXPA02010884A (es) | 2000-05-05 | 2003-03-27 | Aerogen Ireland Ltd | Aparato y metodo para el suministro de medicamentos al sistema respiratorio. |
US8336545B2 (en) * | 2000-05-05 | 2012-12-25 | Novartis Pharma Ag | Methods and systems for operating an aerosol generator |
US7600511B2 (en) * | 2001-11-01 | 2009-10-13 | Novartis Pharma Ag | Apparatus and methods for delivery of medicament to a respiratory system |
US7971588B2 (en) * | 2000-05-05 | 2011-07-05 | Novartis Ag | Methods and systems for operating an aerosol generator |
WO2001087378A2 (en) | 2000-05-12 | 2001-11-22 | Dura Pharmaceuticals, Inc. | Compressed gas dry powder inhaler |
US6637430B1 (en) | 2000-06-16 | 2003-10-28 | Ponwell Enterprises Limited | Respiratory delivery system with power/medicament recharge assembly |
CA2415297A1 (en) | 2000-07-15 | 2002-01-24 | Glaxo Group Limited | Medicament dispenser |
WO2002009669A2 (en) * | 2000-08-01 | 2002-02-07 | Inhale Therapeutic Systems, Inc. | Apparatus and process to produce particles having a narrow size distribution and particles made thereby |
CA2708703C (en) | 2000-12-27 | 2012-12-04 | Alan Bruce Montgomery | Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections |
US6758837B2 (en) | 2001-02-08 | 2004-07-06 | Pharmacia Ab | Liquid delivery device and method of use thereof |
US20030072717A1 (en) | 2001-02-23 | 2003-04-17 | Vapotronics, Inc. | Inhalation device having an optimized air flow path |
US6732944B2 (en) | 2001-05-02 | 2004-05-11 | Aerogen, Inc. | Base isolated nebulizing device and methods |
KR20020087298A (ko) | 2001-05-15 | 2002-11-22 | 김원규 | 야생삼을 주성분으로 함유하는 자양강장용 조성물 |
US20030051728A1 (en) * | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
EP1420841A2 (en) | 2001-08-31 | 2004-05-26 | Rosti, A/S | Inhaler |
JP2003159332A (ja) * | 2001-11-27 | 2003-06-03 | Omron Corp | ネブライザ、サーバ、ネブライザシステム、ネブライザにおける薬剤判別方法、ネブライザにおける薬量検出方法、ネブライザシステムにおける情報管理方法、ネブライザ情報管理プログラム、および該プログラムを記録する記録媒体 |
US6684880B2 (en) | 2001-12-04 | 2004-02-03 | Hewlett-Packard Development Company, L.P. | Applicator for dispensing bioactive compositions and methods for using the same |
US6851626B2 (en) * | 2002-01-07 | 2005-02-08 | Aerogen, Inc. | Methods and devices for nebulizing fluids |
US7458373B2 (en) * | 2002-01-15 | 2008-12-02 | Philip Morris Usa Inc. | Aerosol generator for drug formulation |
EP1474196B1 (en) | 2002-01-15 | 2016-08-17 | Novartis AG | Methods and systems for operating an aerosol generator |
JP2003265994A (ja) | 2002-03-13 | 2003-09-24 | Olympus Optical Co Ltd | 噴霧ヘッド |
CA2478327A1 (en) | 2002-03-20 | 2003-10-02 | Advanced Inhalation Research, Inc. | Hgh (human growth hormone) formulations for pulmonary administration |
WO2003089036A1 (en) | 2002-04-19 | 2003-10-30 | 3M Innovative Properties Company | A spacer for inertial removal of the non-respirable fraction of medicinal aerosols |
JP2006507921A (ja) | 2002-06-28 | 2006-03-09 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 流体分散のための方法および装置 |
WO2004022083A1 (en) | 2002-09-04 | 2004-03-18 | Dsm Ip Assets B.V. | A nutritional and therapeutic composition of an insulin sensitizer and a peptide fraction |
US7070071B2 (en) | 2002-09-23 | 2006-07-04 | Agouron Pharmaceuticals, Inc. | Dispensing apparatus and method for liquid products, particularly medicinal products |
DE10244795A1 (de) | 2002-09-26 | 2004-04-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverinhalator |
US20040230090A1 (en) | 2002-10-07 | 2004-11-18 | Hegde Anant V. | Vascular assist device and methods |
GB2396825B (en) | 2002-11-20 | 2004-12-08 | Profile Respiratory Systems Lt | Improved inhalation method and apparatus |
US7849850B2 (en) | 2003-02-28 | 2010-12-14 | Battelle Memorial Institute | Nozzle for handheld pulmonary aerosol delivery device |
US20100222752A1 (en) | 2003-05-20 | 2010-09-02 | Collins Jr James F | Ophthalmic fluid delivery system |
CA2526362C (en) | 2003-05-20 | 2012-10-09 | James F. Collins | Ophthalmic drug delivery system |
US8012136B2 (en) | 2003-05-20 | 2011-09-06 | Optimyst Systems, Inc. | Ophthalmic fluid delivery device and method of operation |
US8616195B2 (en) | 2003-07-18 | 2013-12-31 | Novartis Ag | Nebuliser for the production of aerosolized medication |
US20050172958A1 (en) | 2003-08-20 | 2005-08-11 | The Brigham And Women's Hospital, Inc. | Inhalation device and system for the remote monitoring of drug administration |
US20050133024A1 (en) | 2003-11-25 | 2005-06-23 | Coifman Robert E. | Devices for measuring inspiratory airflow |
US20050121025A1 (en) | 2003-12-04 | 2005-06-09 | Gamard Stephan C.F. | Portable gas operating inhaler |
US20050150489A1 (en) * | 2004-01-12 | 2005-07-14 | Steve Dunfield | Dispensing medicaments based on rates of medicament action |
US7819115B2 (en) * | 2004-01-30 | 2010-10-26 | Hewlett-Packard Development Company, L.P. | Inhalers and methods of controlling airflow in inhalers |
US9022027B2 (en) | 2004-02-20 | 2015-05-05 | Pneumoflex Systems, Llc | Nebulizer with intra-oral vibrating mesh |
US8109266B2 (en) | 2004-02-20 | 2012-02-07 | Pneumoflex Systems, Llc | Nebulizer having flow meter function |
AU2005216205B2 (en) | 2004-02-24 | 2010-07-15 | Microdose Therapeutx, Inc. | Directional flow sensor inhaler |
AU2005262940B2 (en) | 2004-04-02 | 2010-07-01 | Creare Incorporated | Aerosol delivery systems and methods |
US8056556B2 (en) | 2004-04-12 | 2011-11-15 | Hewlett-Packard Development Company, L.P. | Inhaler nozzle maintenance apparatus and method |
US20080059228A1 (en) | 2004-04-24 | 2008-03-06 | Christopher Bossi | Operation Of A Remote Medication Management System |
EP1776151A1 (en) | 2004-08-02 | 2007-04-25 | Canon Kabushiki Kaisha | Inhaling apparatus |
JP4695940B2 (ja) | 2004-08-02 | 2011-06-08 | キヤノン株式会社 | 吸入装置 |
EP1655021B1 (en) | 2004-11-09 | 2008-10-29 | Novagali Pharma SA | Oil-in-water type emulsion with low concentration of cationic agent and positive zeta potential |
GB0427858D0 (en) | 2004-12-20 | 2005-01-19 | Glaxo Group Ltd | Manifold for use in medicament dispenser |
JP2006212203A (ja) | 2005-02-03 | 2006-08-17 | Canon Inc | 吸入装置、及び液剤吐出カートリッジ |
DE102005006374B3 (de) | 2005-02-11 | 2006-07-20 | Pari GmbH Spezialisten für effektive Inhalation | Aerosolerzeugungsvorrichtung und Inhalationstherapiegerät mit einer derartigen Vorrichtung |
EP1861009B1 (en) * | 2005-03-17 | 2019-05-22 | Robert E. Coifman | Apparatus and method for intelligent electronic peak flow meters |
US7219664B2 (en) | 2005-04-28 | 2007-05-22 | Kos Life Sciences, Inc. | Breath actuated inhaler |
EP1893273B1 (en) | 2005-05-18 | 2014-06-25 | Nektar Therapeutics | Adapter for use with aerosolization device for endobronchial therapy |
CN101208123B (zh) | 2005-05-25 | 2012-09-19 | 亚罗擎公司 | 振动系统和方法 |
US20070157931A1 (en) | 2005-07-11 | 2007-07-12 | Richard Parker | System and method for optimized delivery of an aerosol to the respiratory tract |
IL169807A (en) | 2005-07-21 | 2015-03-31 | Steadymed Ltd | Device for administering a drug |
US8367734B1 (en) | 2005-08-11 | 2013-02-05 | Amphastar Pharmaceuticals Inc. | Stable epinephrine suspension formulation with high inhalation delivery efficiency |
WO2008048234A2 (en) | 2005-08-26 | 2008-04-24 | North Carolina State University | Inhaler system for targeted maximum drug-aerosol delivery |
KR100802149B1 (ko) | 2005-09-16 | 2008-02-11 | 주식회사 진생사이언스 | 혈관 손상에 의한 질환 예방 및 치료용 조성물 |
WO2007045237A1 (en) | 2005-10-18 | 2007-04-26 | Equine Nebulizer Aps | Inhalation device for providing a mist of nebulised liquid medical solution to a user |
US8753308B2 (en) | 2006-01-06 | 2014-06-17 | Acelrx Pharmaceuticals, Inc. | Methods for administering small volume oral transmucosal dosage forms using a dispensing device |
DE102006006183A1 (de) | 2006-02-10 | 2007-08-16 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung für die Anwendung bei Frühgeborenen und Kleinkindern |
US20090114218A1 (en) | 2006-04-13 | 2009-05-07 | Ada Technologies, Inc. | Electrotherapeutic treatment device and method |
US7841338B2 (en) | 2006-04-13 | 2010-11-30 | Boehringer Ingelheim International Gmbh | Dispensing device |
US8376525B2 (en) | 2006-09-08 | 2013-02-19 | Canon Kabushiki Kaisha | Liquid discharge head and method of manufacturing the same |
US20080142010A1 (en) | 2006-09-20 | 2008-06-19 | Next Safety, Inc. | Systems, methods, and apparatuses for pulmonary drug delivery |
NL2000309C2 (nl) * | 2006-11-09 | 2008-05-13 | Indes Holding Bv | Systeem voor het kunstmatig beademen van personen. |
FR2908329B1 (fr) * | 2006-11-14 | 2011-01-07 | Telemaq | Dispositif et methode de distribution de fluide par ultrasons |
WO2008116165A2 (en) * | 2007-03-21 | 2008-09-25 | Next Safety, Inc. | Methods and systems of delivering medication via inhalation |
US20090235925A1 (en) | 2007-03-28 | 2009-09-24 | John Sylvester Power | Aerosolisation system |
JP4877011B2 (ja) | 2007-03-28 | 2012-02-15 | ブラザー工業株式会社 | 液滴噴射装置 |
WO2008117264A1 (en) | 2007-03-28 | 2008-10-02 | Stamford Devices Limited | Insufflation of body cavities |
US20080271732A1 (en) | 2007-05-01 | 2008-11-06 | Next Safety, Inc. | Pulmonary Drug Delivery Devices Configured to Control the Size of Administered Droplets |
EP1992380A1 (en) | 2007-05-16 | 2008-11-19 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
US8528544B2 (en) | 2007-05-30 | 2013-09-10 | Canon Kabushiki Kaisha | Inhaler |
EP2203155A1 (en) | 2007-09-25 | 2010-07-07 | Novartis Ag | Treatment of pulmonary disorders with aerosolized medicaments such as vancomycin |
AU2012258488A1 (en) | 2007-09-25 | 2013-01-10 | Nektar Therapeutics | Treatment of pulmonary disorders with aerosolized medicaments such as vancomycin |
JP5421272B2 (ja) | 2007-10-12 | 2014-02-19 | リゾルヴィクス・ファーマシューティカルズ・インコーポレイテッド | 眼病治療のための組成物及び方法 |
JP2009106467A (ja) | 2007-10-30 | 2009-05-21 | Canon Inc | 吸入装置 |
US20090212133A1 (en) | 2008-01-25 | 2009-08-27 | Collins Jr James F | Ophthalmic fluid delivery device and method of operation |
WO2009111612A1 (en) * | 2008-03-07 | 2009-09-11 | Novartis Ag | Aerosolization device |
PT2285439E (pt) | 2008-04-04 | 2014-03-25 | Nektar Therapeutics | Dispositivo de aerossolização |
US7891580B2 (en) | 2008-04-30 | 2011-02-22 | S.C. Johnson & Son, Inc. | High volume atomizer for common consumer spray products |
WO2009155581A1 (en) | 2008-06-20 | 2009-12-23 | Mannkind Corporation | An interactive apparatus and method for real-time profiling of inhalation efforts |
EP2337600B1 (en) | 2008-09-26 | 2019-09-18 | Stamford Devices Limited | Supplemental oxygen delivery system |
JP2012503519A (ja) | 2008-09-26 | 2012-02-09 | スタンフォード・デバイシズ・リミテッド | ネブライザー装置 |
US20090192443A1 (en) | 2008-10-06 | 2009-07-30 | Collins Jr James F | Ophthalmic fluid delivery device and method of operation |
JP5848608B2 (ja) * | 2008-12-01 | 2016-01-27 | トリコーンテク コーポレーションTricornTech Corporation | 喘息、結核及び肺癌の診断及び疾患管理のための呼気分析システム及び方法 |
DE102008054431B3 (de) | 2008-12-09 | 2010-06-17 | Pari Pharma Gmbh | Aerosoltherapievorrichtung |
JP2010143048A (ja) | 2008-12-18 | 2010-07-01 | Fuji Xerox Co Ltd | 液滴吐出ヘッドおよび液滴吐出装置 |
US20120048265A1 (en) | 2009-05-11 | 2012-03-01 | Koninklijke Philips Electronics N.V. | Aerosol drug delivery apparatus and method |
KR101761433B1 (ko) | 2009-10-09 | 2017-07-25 | 필립모리스 프로덕츠 에스.에이. | 다중-구성요소 위크를 포함하는 에어로졸 발생기 |
WO2011061480A1 (en) | 2009-11-18 | 2011-05-26 | Reckitt Benckiser Llc | Surface treatment device and method |
DK2515977T3 (en) | 2009-12-26 | 2018-04-16 | Inspiro Medical Ltd | DEVICE FOR DELIVERY OF DRY POWDER |
WO2011091268A2 (en) * | 2010-01-21 | 2011-07-28 | Asthma Signals, Inc. | Early warning method and system for chronic disease management |
US20110230820A1 (en) | 2010-03-18 | 2011-09-22 | Aerosurgical Limited | Insufflation of body cavities |
CA2795712A1 (en) * | 2010-04-14 | 2011-10-20 | Jui-Jen Lee | Atomization cleaning health care device and atomization method thereof |
US10154923B2 (en) | 2010-07-15 | 2018-12-18 | Eyenovia, Inc. | Drop generating device |
ES2787254T3 (es) | 2010-07-15 | 2020-10-15 | Eyenovia Inc | Suministro de fármacos oftálmicos |
JP2013531548A (ja) | 2010-07-15 | 2013-08-08 | コリンシアン オフサルミック,インコーポレイティド | 遠隔治療及び遠隔モニタリングを実施する方法及びシステム |
JP5964826B2 (ja) | 2010-07-15 | 2016-08-03 | アイノビア,インコーポレイティド | 滴生成デバイス |
US9757528B2 (en) | 2010-08-23 | 2017-09-12 | Darren Rubin | Nebulizer having different negative pressure threshold settings |
EP2457609A1 (en) | 2010-11-24 | 2012-05-30 | PARI Pharma GmbH | Aerosol generator |
BR112013016671B1 (pt) | 2010-12-28 | 2020-12-15 | Stamford Devices Ltd | Placa com abertura nebulizadora, malha vibratória do tipo nebulizador e método para a fabricação da dita placa |
US9452274B2 (en) | 2011-01-20 | 2016-09-27 | Pneumoflex Systems, Llc | Metered dose atomizer |
EP2790620A1 (en) | 2011-12-12 | 2014-10-22 | Corinthian Ophthalmic, Inc. | High modulus polymeric ejector mechanism, ejector device, and methods of use |
EP2797652B1 (en) | 2011-12-27 | 2018-11-21 | Vectura GmbH | Inhalation device with feedback system |
EP2819733A1 (en) | 2012-02-27 | 2015-01-07 | Laerdal Global Health AS | Resuscitation assembly with peep valve |
IN2014DN08290A (ja) * | 2012-03-09 | 2015-05-15 | Vectura Gmbh | |
CA2870181C (en) | 2012-04-10 | 2020-12-22 | Corinthian Ophthalmic, Inc. | Spray ejector mechanisms and devices providing charge isolation and controllable droplet charge, and low dosage volume opthalmic administration |
US20130269694A1 (en) | 2012-04-16 | 2013-10-17 | Dance Pharmaceuticals, Inc. | Inhaler controlled by mobile device |
BR112014026171A2 (pt) | 2012-04-20 | 2017-07-18 | Eyenovia Inc | dispositivo ejetor por aspersão e métodos de uso |
US20130284165A1 (en) | 2012-04-27 | 2013-10-31 | Medstar Health | System and method for treating a medical condition using an aerosolized solution |
EP2849692A1 (en) * | 2012-05-14 | 2015-03-25 | Eyenovia, Inc. | Laminar flow droplet generator device and methods of use |
SG10201602609XA (en) | 2012-05-15 | 2016-05-30 | Eyenovia Inc | Ejector devices, methods, drivers, and circuits therefor |
CN108743537B (zh) | 2012-05-21 | 2021-06-11 | 英斯麦德公司 | 治疗肺部感染的系统 |
EP3639733B1 (en) | 2012-05-30 | 2022-10-26 | ResMed Sensor Technologies Limited | Apparatus for monitoring cardio-pulmonary health |
JP6385922B2 (ja) | 2012-06-11 | 2018-09-05 | スタムフォード・ディバイセズ・リミテッド | ネブライザのための開口板を製造する方法 |
SI2724741T1 (sl) | 2012-10-26 | 2017-10-30 | Vectura Gmbh | Inhalacijska naprava za uporabo v terapiji z aerosolom |
US10046123B2 (en) * | 2012-10-31 | 2018-08-14 | Inhaletech Llc | Systems and methods for administering pulmonary medications |
JP6429788B6 (ja) | 2012-11-28 | 2019-01-30 | フォンテム ホールディングス 1 ビー. ブイ. | 化合物送達のためのデバイス |
WO2014204511A2 (en) | 2013-06-18 | 2014-12-24 | Isonea Limited | Compliance monitoring for asthma inhalers |
US10758689B2 (en) * | 2013-07-03 | 2020-09-01 | Sanara Tech Ltd. | Metered dose inhaler and methods thereof |
WO2015005958A1 (en) * | 2013-07-09 | 2015-01-15 | Pulmone Advanced Medical Devices, Ltd. | Determining respiratory parameters |
WO2015009792A1 (en) | 2013-07-16 | 2015-01-22 | Palo Alto Health Sciences, Inc. | Methods and systems for quantitative colorimetric capnometry |
US10194693B2 (en) | 2013-09-20 | 2019-02-05 | Fontem Holdings 1 B.V. | Aerosol generating device |
TW201511782A (zh) | 2013-09-30 | 2015-04-01 | Healthkare Entpr Co Ltd | 拋棄式保健器物之結構 |
EP3068244A4 (en) | 2013-11-15 | 2017-07-05 | VMR Products, LLC | Vaporizer with cover sleeve |
WO2015091171A1 (en) | 2013-12-19 | 2015-06-25 | Koninklijke Philips N.V. | An assembly for use in liquid a droplet apparatus |
NZ760541A (en) | 2014-01-10 | 2022-08-26 | Avalyn Pharma Inc | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
US10709173B2 (en) | 2014-02-06 | 2020-07-14 | Juul Labs, Inc. | Vaporizer apparatus |
EP2910268A1 (en) | 2014-02-25 | 2015-08-26 | PARI Pharma GmbH | Inhalator and inhalator set |
NO2709641T3 (ja) | 2014-03-10 | 2018-05-12 | ||
CA2949121A1 (en) | 2014-05-15 | 2015-11-19 | Bristol-Myers Squibb Company | Treatment of lung cancer using a combination of an anti-pd-1 antibody and another anti-cancer agent |
US10610651B2 (en) | 2014-06-09 | 2020-04-07 | Aerami Therapeutics, Inc. | Self-puncturing liquid drug cartridges and associated dispenser |
EP3160565B1 (en) | 2014-06-30 | 2021-08-18 | Syqe Medical Ltd. | Devices and systems for pulmonary delivery of active agents |
DK3160558T3 (da) | 2014-06-30 | 2020-04-27 | Syqe Medical Ltd | Strømningsregulerende indåndingsanordning |
US10857313B2 (en) | 2014-07-01 | 2020-12-08 | Aerami Therapeutics, Inc. | Liquid nebulization systems and methods |
US10471222B2 (en) | 2014-07-01 | 2019-11-12 | Dance Biopharm Inc. | Aerosolization system with flow restrictor and feedback device |
FR3023735B1 (fr) | 2014-07-17 | 2016-07-29 | Areco Finances Et Tech - Arfitec | Nebuliseur compact pour rafraichir l'air |
SI3204095T1 (sl) | 2014-10-10 | 2019-08-30 | Ablynx N.V. | Inhalacijska naprava za uporabo pri zdravljenju bolezni dihal z aerosolom |
WO2016055656A1 (en) | 2014-10-10 | 2016-04-14 | Ablynx N.V. | Methods of treating rsv infections |
CN104586396B (zh) | 2014-12-12 | 2017-04-26 | 歌尔股份有限公司 | 一种肺活量的测试方法和设备 |
US20160325055A1 (en) | 2015-05-08 | 2016-11-10 | Lunatech, Llc | Device To Deliver Cannabidiol And Associated Compounds To Promote Health |
CN205019058U (zh) | 2015-07-31 | 2016-02-10 | 天津信仁科技发展有限公司 | 一种基于云平台的肺功能检测训练数据服务系统 |
CN204995458U (zh) | 2015-09-15 | 2016-01-27 | 南京瀚雅健康科技有限公司 | 运动心肺测试仪 |
WO2017056103A1 (en) | 2015-10-01 | 2017-04-06 | Anuraag Reddy Kuchukulla | A controlled nicotine delivery system which restricts, and gradually attenuates the dosage |
US10328218B2 (en) * | 2015-10-15 | 2019-06-25 | Engineered Medical Systems, Inc. | Respiratory medicament nebulizer system |
US11285285B2 (en) | 2016-05-03 | 2022-03-29 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
EP3248641B1 (en) | 2016-05-23 | 2019-10-23 | Presspart Manufacturing Ltd. | Dry powder inhaler |
WO2018126238A1 (en) | 2016-12-30 | 2018-07-05 | Bvw Holding Ag | Stents with improved fixation |
EP4223335A3 (en) | 2017-05-19 | 2023-11-08 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
US11738158B2 (en) | 2017-10-04 | 2023-08-29 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device and methods of use |
EP3697481A4 (en) | 2017-10-17 | 2021-07-14 | Pneuma Respiratory, Inc. | NASAL DRUG DELIVERY DEVICE AND METHOD OF USE |
JP2021502178A (ja) * | 2017-11-08 | 2021-01-28 | ニューマ・リスパイラトリー・インコーポレイテッド | 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法 |
WO2019195239A1 (en) | 2018-04-02 | 2019-10-10 | Pneuma Respiratory, Inc. | Handheld digital nebulizer device and methods of use |
KR20190122453A (ko) | 2018-04-20 | 2019-10-30 | (의료)길의료재단 | 진세노사이드 Re를 함유하는 호흡기 질환 예방 또는 치료용 약학적 조성물 |
CN111989005A (zh) | 2018-05-16 | 2020-11-24 | 菲利普莫里斯生产公司 | 雾化器及用于雾化器的网格 |
EP3860768A4 (en) | 2018-10-01 | 2022-06-29 | Pneuma Respiratory, Inc. | Delivery of low surface tension compositions to the pulmonary system via electronic breath actuated droplet delivery device |
US20220080137A1 (en) | 2019-01-24 | 2022-03-17 | Pneuma Respiratory, Inc. | Electronic breath actuated droplet delivery systems with dose metering capabilities, inhalation topography methods, and related methods of use |
US20220226587A1 (en) | 2019-05-09 | 2022-07-21 | Pneuma Respiratory, Inc. | Ultrasonic breath actuated respiratory droplet delivery device and methods of use |
AU2020308104A1 (en) | 2019-06-27 | 2022-02-03 | Pneuma Respiratory, Inc. | Delivery of small droplets to the respiratory system via electronic breath actuated droplet delivery device |
-
2017
- 2017-05-03 US US16/098,805 patent/US11285285B2/en active Active
- 2017-05-03 WO PCT/US2017/030925 patent/WO2017192778A1/en unknown
- 2017-05-03 AU AU2017259982A patent/AU2017259982B2/en active Active
- 2017-05-03 EP EP17793294.4A patent/EP3451905A4/en active Pending
- 2017-05-03 WO PCT/US2017/030921 patent/WO2017192774A1/en active Application Filing
- 2017-05-03 WO PCT/US2017/030929 patent/WO2017192782A1/en active Application Filing
- 2017-05-03 US US16/098,806 patent/US20190134330A1/en active Pending
- 2017-05-03 US US16/098,698 patent/US20210236745A1/en not_active Abandoned
- 2017-05-03 JP JP2019510564A patent/JP2019523109A/ja active Pending
- 2017-05-03 US US16/098,721 patent/US11285283B2/en active Active
- 2017-05-03 US US16/098,802 patent/US11285274B2/en active Active
- 2017-05-03 JP JP2019510563A patent/JP7407593B2/ja active Active
- 2017-05-03 CN CN201780037054.7A patent/CN109475707A/zh active Pending
- 2017-05-03 US US16/098,800 patent/US11285284B2/en active Active
- 2017-05-03 WO PCT/US2017/030913 patent/WO2017192767A1/en unknown
- 2017-05-03 CA CA3022918A patent/CA3022918A1/en active Pending
- 2017-05-03 WO PCT/US2017/030917 patent/WO2017192771A1/en unknown
- 2017-05-03 KR KR1020207016495A patent/KR102295739B1/ko active IP Right Grant
- 2017-05-03 CA CA3022916A patent/CA3022916C/en active Active
- 2017-05-03 AU AU2017260444A patent/AU2017260444B2/en active Active
- 2017-05-03 CN CN201780036615.1A patent/CN109414178B/zh active Active
- 2017-05-03 EP EP17793284.5A patent/EP3452150B1/en active Active
- 2017-05-03 CN CN201780037744.2A patent/CN109475709B/zh active Active
- 2017-05-03 WO PCT/US2017/030919 patent/WO2017192773A1/en active Application Filing
- 2017-05-03 JP JP2018569173A patent/JP6774508B2/ja active Active
- 2017-05-03 KR KR1020187034936A patent/KR102122887B1/ko active IP Right Grant
- 2017-05-03 EP EP17793287.8A patent/EP3452152A4/en active Pending
- 2017-05-16 US US15/596,970 patent/US9956360B2/en active Active
- 2017-05-16 US US15/596,935 patent/US9962507B2/en active Active
-
2018
- 2018-03-02 US US15/910,826 patent/US10898666B2/en active Active
- 2018-08-08 US US16/058,857 patent/US10449314B2/en active Active
- 2018-11-01 IL IL262735A patent/IL262735B/en active IP Right Grant
-
2019
- 2019-07-29 US US16/525,014 patent/US10525220B2/en active Active
- 2019-08-02 AU AU2019210668A patent/AU2019210668B2/en active Active
- 2019-12-25 JP JP2019233651A patent/JP7072554B2/ja active Active
-
2021
- 2021-01-22 US US17/156,374 patent/US20220008669A1/en not_active Abandoned
- 2021-05-18 JP JP2021083714A patent/JP2021130013A/ja active Pending
-
2022
- 2022-10-14 JP JP2022165165A patent/JP2022188270A/ja active Pending
-
2023
- 2023-02-15 US US18/169,558 patent/US20230277781A1/en not_active Abandoned
- 2023-04-18 JP JP2023067741A patent/JP2023093609A/ja active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020032387A1 (en) * | 1996-05-08 | 2002-03-14 | Jacob Geva | Apparatus and method for remote spirometry |
US20140213925A1 (en) * | 2011-09-20 | 2014-07-31 | Isonea Limited | Systems, methods and kits for measuring respiratory rate and dynamically predicting respiratory episodes |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN109414178B (zh) | 用于肺部健康管理的系统和方法 | |
US11497867B2 (en) | Smart nebulizer | |
JP6957520B2 (ja) | スマート弁付き保持チャンバ | |
US20160325058A1 (en) | Systems and methods for managing pulmonary medication delivery | |
US20150273165A1 (en) | Systems and methods for administering pulmonary medications | |
JP7005660B2 (ja) | エアロゾル噴霧システムの制御デバイス | |
JP6305994B2 (ja) | 患者の肺機能をモニタするための方法及びシステム | |
US8807131B1 (en) | Compliance monitoring for asthma inhalers | |
US11273271B2 (en) | Aerosolization system with flow restrictor and feedback device | |
CN111526914A (zh) | 电子呼吸致动式直线型液滴输送装置及其使用方法 | |
JP2020500632A (ja) | 吸入器 | |
JP2022508519A (ja) | 電子呼吸作動式エアロゾル吸入デバイスを介した肺系統への低表面張力組成物の送達 | |
CN112638455A (zh) | 检测药物流的呼吸系统和方法 | |
US20190298941A1 (en) | Adjunct Diagnostic Device and Method | |
JP2023145780A (ja) | 携帯用呼吸治療及び吸入・呼気測定装置並びに関連方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20191107 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20201130 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20210120 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20210405 |
|
A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20210810 |