CY1110989T1 - Χρηση 3-(4-αμινο-1-οξο-1,3-διυδρο-ισοϊνδολ-2-υλο)-πιπεριδινο-2,6-διονης για την αντιμετωπιση λεμφωματων κυτταρων του μανδυα - Google Patents
Χρηση 3-(4-αμινο-1-οξο-1,3-διυδρο-ισοϊνδολ-2-υλο)-πιπεριδινο-2,6-διονης για την αντιμετωπιση λεμφωματων κυτταρων του μανδυαInfo
- Publication number
- CY1110989T1 CY1110989T1 CY20101101137T CY101101137T CY1110989T1 CY 1110989 T1 CY1110989 T1 CY 1110989T1 CY 20101101137 T CY20101101137 T CY 20101101137T CY 101101137 T CY101101137 T CY 101101137T CY 1110989 T1 CY1110989 T1 CY 1110989T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- isoindol
- piperidino
- dione
- dihydro
- Prior art date
Links
- -1 4-AMINO-1-oxo-1,3-dihydro-isoindol-2-yl Chemical group 0.000 title 1
- 210000001165 lymph node Anatomy 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- GOTYRUGSSMKFNF-UHFFFAOYSA-N lenalidomide Chemical compound C1C=2C(N)=CC=CC=2C(=O)N1C1CCC(=O)NC1=O GOTYRUGSSMKFNF-UHFFFAOYSA-N 0.000 abstract 2
- 208000025205 Mantle-Cell Lymphoma Diseases 0.000 abstract 1
- 238000001815 biotherapy Methods 0.000 abstract 1
- 238000002512 chemotherapy Methods 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000001794 hormone therapy Methods 0.000 abstract 1
- 230000002519 immonomodulatory effect Effects 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 229960004942 lenalidomide Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
- 229940120975 revlimid Drugs 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83575206P | 2006-08-03 | 2006-08-03 | |
| EP07811048A EP2046331B1 (en) | 2006-08-03 | 2007-08-02 | Use of 3- (4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for the treatment of mantle cell lymphomas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1110989T1 true CY1110989T1 (el) | 2015-06-11 |
Family
ID=38691762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20101101137T CY1110989T1 (el) | 2006-08-03 | 2010-12-10 | Χρηση 3-(4-αμινο-1-οξο-1,3-διυδρο-ισοϊνδολ-2-υλο)-πιπεριδινο-2,6-διονης για την αντιμετωπιση λεμφωματων κυτταρων του μανδυα |
Country Status (26)
| Country | Link |
|---|---|
| US (7) | US20080038263A1 (OSRAM) |
| EP (1) | EP2046331B1 (OSRAM) |
| JP (2) | JP5465005B2 (OSRAM) |
| KR (2) | KR20140082859A (OSRAM) |
| CN (2) | CN102908346A (OSRAM) |
| AR (1) | AR062265A1 (OSRAM) |
| AT (1) | ATE486601T1 (OSRAM) |
| AU (1) | AU2007282027B2 (OSRAM) |
| CA (2) | CA2659774C (OSRAM) |
| CL (1) | CL2007002218A1 (OSRAM) |
| CY (1) | CY1110989T1 (OSRAM) |
| DE (1) | DE602007010303D1 (OSRAM) |
| DK (1) | DK2046331T3 (OSRAM) |
| ES (1) | ES2351069T3 (OSRAM) |
| HR (1) | HRP20100664T1 (OSRAM) |
| IL (1) | IL196885A (OSRAM) |
| ME (1) | ME01937B (OSRAM) |
| MX (1) | MX2009001268A (OSRAM) |
| PE (1) | PE20081311A1 (OSRAM) |
| PL (1) | PL2046331T3 (OSRAM) |
| PT (1) | PT2046331E (OSRAM) |
| RS (1) | RS51567B (OSRAM) |
| RU (1) | RU2446804C2 (OSRAM) |
| SI (1) | SI2046331T1 (OSRAM) |
| TW (1) | TWI430797B (OSRAM) |
| WO (1) | WO2008019065A1 (OSRAM) |
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| CL2007002218A1 (es) * | 2006-08-03 | 2008-03-14 | Celgene Corp Soc Organizada Ba | Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa. |
| CA2717326C (en) * | 2008-03-11 | 2018-10-23 | Dr. Reddy's Laboratories Ltd. | Preparation of lenalidomide |
| US20110280913A1 (en) * | 2008-07-31 | 2011-11-17 | The Ohio State University | Methods and Compositions for Delivering Therapeutic Agents in the Treatment of B-Cell Related Disorders |
| EP2544687A1 (en) * | 2010-03-12 | 2013-01-16 | Celgene Corporation | Methods for the treatment of non-hodgkin's lymphomas using lenalidomide, and gene and protein biomarkers as a predictor |
| CA2866230C (en) | 2012-05-03 | 2020-08-18 | Janssen R&D Ireland | Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections |
| CN104031122B (zh) * | 2014-06-23 | 2016-05-11 | 常州市肿瘤医院 | 有关Cyclin D蛋白抑制剂多肽及其应用 |
| CN104004056B (zh) * | 2014-06-23 | 2016-08-17 | 王方杰 | 一种关于Cyclin D蛋白抑制剂多肽及其应用 |
| CN104004060B (zh) * | 2014-06-23 | 2016-04-13 | 重庆医科大学 | Cyclin D蛋白抑制剂多肽及其应用 |
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| US11584733B2 (en) | 2017-01-09 | 2023-02-21 | Shuttle Pharmaceuticals, Inc. | Selective histone deacetylase inhibitors for the treatment of human disease |
| CN111372585A (zh) | 2017-11-16 | 2020-07-03 | C4医药公司 | 用于靶蛋白降解的降解剂和降解决定子 |
| US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
| ES2983284T3 (es) | 2018-01-09 | 2024-10-22 | Shuttle Pharmaceuticals Inc | Inhibidores selectivos de histona deacetilasa para el tratamiento de enfermedades humanas |
| JP2021519337A (ja) | 2018-03-26 | 2021-08-10 | シー4 セラピューティクス, インコーポレイテッド | Ikarosの分解のためのセレブロン結合剤 |
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| CN120698985A (zh) | 2018-12-20 | 2025-09-26 | C4医药公司 | 靶向蛋白降解 |
| ES2995214T3 (en) | 2019-03-06 | 2025-02-07 | C4 Therapeutics Inc | Heterocyclic compounds for medical treatment |
| BR112021019669A2 (pt) | 2019-04-12 | 2021-12-07 | C4 Therapeutics Inc | Composto, composição farmacêutica, método para tratar um transtorno, composto para uso na produção de um medicamento, e, uso de um composto no tratamento de um transtorno |
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| CL2004001004A1 (es) * | 2003-05-19 | 2005-03-18 | Upjohn Co | Combinacion farmaceutica que comprende irinotecan y revimid para tratar el mieloma multiple. |
| CL2007002218A1 (es) * | 2006-08-03 | 2008-03-14 | Celgene Corp Soc Organizada Ba | Uso de 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidina 2,6-diona para la preparacion de un medicamento util para el tratamiento de linfoma de celula de capa. |
| WO2009020590A1 (en) * | 2007-08-07 | 2009-02-12 | Celgene Corporation | Methods for treating lymphomas in certain patient populations and screening patients for said therapy |
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2007
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- 2007-08-02 CN CN2012103235264A patent/CN102908346A/zh active Pending
- 2007-08-02 RU RU2009107535/15A patent/RU2446804C2/ru not_active IP Right Cessation
- 2007-08-02 AT AT07811048T patent/ATE486601T1/de active
- 2007-08-02 PL PL07811048T patent/PL2046331T3/pl unknown
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