CY1109345T1 - ΠΑΡΑΓΩΓΑ ΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8-ΥΠΕΡΦΘΟΡΟΑΛΚΥΛΟ-6,7,8,9-ΤΕΤΡΑΫΔΡΟΠΥΡΙΜΙΔΟ (1,2-a) ΠΥΡΙΜΙΔΙΝ-4-ΟΝΗΣ - Google Patents
ΠΑΡΑΓΩΓΑ ΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8-ΥΠΕΡΦΘΟΡΟΑΛΚΥΛΟ-6,7,8,9-ΤΕΤΡΑΫΔΡΟΠΥΡΙΜΙΔΟ (1,2-a) ΠΥΡΙΜΙΔΙΝ-4-ΟΝΗΣInfo
- Publication number
- CY1109345T1 CY1109345T1 CY20091100926T CY091100926T CY1109345T1 CY 1109345 T1 CY1109345 T1 CY 1109345T1 CY 20091100926 T CY20091100926 T CY 20091100926T CY 091100926 T CY091100926 T CY 091100926T CY 1109345 T1 CY1109345 T1 CY 1109345T1
- Authority
- CY
- Cyprus
- Prior art keywords
- alkyl group
- hydrogen atom
- substituted
- ring
- optionally substituted
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Η ευρεσιτεχνία σχετίζεται με ένα παράγωγο υποκατεστημένης πυριμιδόνης, που αναπαριστάται από τον τύπο (I) ή ένα άλας αυτού, όπου: Χ αναπαριστά δύο άτομα υδρογόνου, ένα άτομο θείου, ένα άτομο οξυγόνου ή μία C1-2 αλκυλομάδα και ένα άτομο υδρογόνου∙ Υ αναπαριστά ένα δεσμό, μία καρβονυλομάδα, μία μεθυλενομάδα, προαιρετικά υποκατεστημένη∙ R1 αναπαριστά έναν δακτύλιο με 2, 3 ή 4 πυριδίνες ή ένα δακτύλιο με 2, 4 ή 5 πυριμιδίνες, οι δακτύλιοι είναι προαιρετικά υποκατεστημένοι∙ R2 αναπαριστά μία φαινυλομάδα ή έναν δακτύλιο ναφθαλινίου∙ η φαινυλομάδα και ο δακτύλιος ναφθαλινίου υποκαθίστανται προαιρετικά∙ R3 αναπαριστά ένα άτομο υδρογόνου ή μία C1-6 αλκυλομάδα- R4 αναπαριστά μία C1-2 υπεραλογονωμένη αλκυλομάδα ή μία C1-3 αλογονωμένη αλκυλομάδα∙ R5 αναπαριστά ένα άτομο υδρογόνου∙ μία C1-6 αλκυλομάδα ή ένα άτομο αλογόνου∙ n αναπαριστά 0 έως 3∙ και p+q=0 έως 3.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03290728A EP1460076A1 (en) | 2003-03-21 | 2003-03-21 | Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives |
| EP04721905A EP1608653B1 (en) | 2003-03-21 | 2004-03-19 | SUBSTITUTED 8-PERFLUOROALKYL-6,7,8,9-TETRAHYDROPYRIMIDO (1,2- a) PYRIMIDIN-4-ONE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1109345T1 true CY1109345T1 (el) | 2014-07-02 |
Family
ID=32799141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20091100926T CY1109345T1 (el) | 2003-03-21 | 2009-09-02 | ΠΑΡΑΓΩΓΑ ΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8-ΥΠΕΡΦΘΟΡΟΑΛΚΥΛΟ-6,7,8,9-ΤΕΤΡΑΫΔΡΟΠΥΡΙΜΙΔΟ (1,2-a) ΠΥΡΙΜΙΔΙΝ-4-ΟΝΗΣ |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US7217715B2 (el) |
| EP (2) | EP1460076A1 (el) |
| JP (1) | JP4572194B2 (el) |
| KR (1) | KR101070075B1 (el) |
| CN (1) | CN100368412C (el) |
| AR (1) | AR053082A1 (el) |
| AT (1) | ATE433977T1 (el) |
| AU (1) | AU2004222105B2 (el) |
| BR (1) | BRPI0408605A (el) |
| CA (1) | CA2517774C (el) |
| CY (1) | CY1109345T1 (el) |
| DE (1) | DE602004021572D1 (el) |
| DK (1) | DK1608653T3 (el) |
| EA (1) | EA009198B1 (el) |
| ES (1) | ES2328812T3 (el) |
| HK (1) | HK1088893A1 (el) |
| IL (1) | IL170634A (el) |
| MX (1) | MXPA05010112A (el) |
| NO (1) | NO20054331L (el) |
| NZ (1) | NZ542224A (el) |
| PL (1) | PL1608653T3 (el) |
| PT (1) | PT1608653E (el) |
| SI (1) | SI1608653T1 (el) |
| TW (1) | TWI322809B (el) |
| WO (1) | WO2004083210A1 (el) |
| ZA (1) | ZA200507192B (el) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1460076A1 (en) * | 2003-03-21 | 2004-09-22 | Sanofi-Synthelabo | Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives |
| JP4277826B2 (ja) | 2005-06-23 | 2009-06-10 | 住友電気工業株式会社 | 窒化物結晶、窒化物結晶基板、エピ層付窒化物結晶基板、ならびに半導体デバイスおよびその製造方法 |
| US8771552B2 (en) * | 2005-06-23 | 2014-07-08 | Sumitomo Electric Industries, Ltd. | Group III nitride crystal substrate, epilayer-containing group III nitride crystal substrate, semiconductor device and method of manufacturing the same |
| US9708735B2 (en) | 2005-06-23 | 2017-07-18 | Sumitomo Electric Industries, Ltd. | Group III nitride crystal substrate, epilayer-containing group III nitride crystal substrate, semiconductor device and method of manufacturing the same |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| CA2620333A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
| WO2007053596A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| EP1790649A1 (en) * | 2005-11-21 | 2007-05-30 | Sanofi-Aventis | Substituted bicyclic pyrimidone derivatives |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| JP2009536669A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | アンジオテンシン調節による神経新生 |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| EP1939187A1 (en) * | 2006-12-20 | 2008-07-02 | Sanofi-Aventis | Substituted heteroaryl pyridopyrimidone derivatives |
| EP2138493A1 (en) | 2008-06-26 | 2009-12-30 | Sanofi-Aventis | Substituted pyrimidone derivatives |
| EP2138495A1 (en) | 2008-06-26 | 2009-12-30 | sanofi-aventis | Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives |
| EP2138498A1 (en) | 2008-06-26 | 2009-12-30 | sanofi-aventis | Substituted tricyclic derivatives against neurodegenerative diseases |
| EP2138488A1 (en) | 2008-06-26 | 2009-12-30 | sanofi-aventis | 4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases |
| EP2138485A1 (en) | 2008-06-26 | 2009-12-30 | sanofi-aventis | Substituted N-Oxide pyrazine derivatives |
| EP2138494A1 (en) * | 2008-06-26 | 2009-12-30 | Sanofi-Aventis | Substituted alkyl pyrimidin-4-one derivatives |
| EP2138492A1 (en) * | 2008-06-26 | 2009-12-30 | Sanofi-Aventis | Substituted pyrimidin-4-one derivatives |
| JP5655070B2 (ja) | 2009-07-02 | 2015-01-14 | サノフイ | 新規６，７，８，９−テトラヒドロピリミド｛１，２−ａ｝ピリミジン−４−オン誘導体、これらの調製およびこれらの医薬的使用 |
| PL2655375T3 (pl) | 2010-12-23 | 2015-05-29 | Sanofi Sa | Pochodne pirymidynonu, ich wytwarzanie i ich farmaceutyczne zastosowanie |
| FR2992314B1 (fr) | 2012-06-22 | 2015-10-16 | Sanofi Sa | Nouveaux derives de 2,3-dihydro-1h-imidazo{1,2-a}pyrimidin-5-one et 1,2,3,4-tetrahydro-pyrimido{1,2-a}pyrimidin-6-one comportant une morpholine substituee, leur preparation et leur utilisation pharmaceutique |
| FR2992316A1 (fr) | 2012-06-22 | 2013-12-27 | Sanofi Sa | Derives de pyrimidinones, leur preparation et leur application en therapeutique |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1136482A1 (en) * | 2000-03-23 | 2001-09-26 | Sanofi-Synthelabo | 2-Amino-3-(alkyl)-pyrimidone derivatives as GSK3beta inhibitors |
| JP2001270884A (ja) * | 2000-03-23 | 2001-10-02 | Mitsubishi-Tokyo Pharmaceuticals Inc | ピリミドン誘導体 |
| WO2002018386A1 (en) * | 2000-09-01 | 2002-03-07 | Sanofi-Synthelabo | 2-PYRIDINYL-6,7,8,9-TETRAHYDROPYRIMIDO[1,2-a]PYRIMIDIN-4-ONE AND 7-PYRIDINYL-2,3-DIHYDROIMIDAZO[1,2-a]PYRIMIDIN-5(1H)ONE DERIVATI VES |
| EP1184383A1 (en) * | 2000-09-01 | 2002-03-06 | Sanofi-Synthelabo | 9-[Alkyl], 9-[(heteroaryl)alkyl] and 9-[(aryl)alkyl]-2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a]pyrimidin-4-one derivatives |
| EP1460076A1 (en) * | 2003-03-21 | 2004-09-22 | Sanofi-Synthelabo | Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives |
-
2003
- 2003-03-21 EP EP03290728A patent/EP1460076A1/en not_active Withdrawn
-
2004
- 2004-03-17 TW TW093107078A patent/TWI322809B/zh not_active IP Right Cessation
- 2004-03-19 PL PL04721905T patent/PL1608653T3/pl unknown
- 2004-03-19 CA CA2517774A patent/CA2517774C/en not_active Expired - Fee Related
- 2004-03-19 KR KR1020057017571A patent/KR101070075B1/ko not_active IP Right Cessation
- 2004-03-19 NZ NZ542224A patent/NZ542224A/en not_active IP Right Cessation
- 2004-03-19 JP JP2006505151A patent/JP4572194B2/ja not_active Expired - Fee Related
- 2004-03-19 EP EP04721905A patent/EP1608653B1/en not_active Expired - Lifetime
- 2004-03-19 AU AU2004222105A patent/AU2004222105B2/en not_active Ceased
- 2004-03-19 DE DE602004021572T patent/DE602004021572D1/de not_active Expired - Lifetime
- 2004-03-19 ZA ZA200507192A patent/ZA200507192B/xx unknown
- 2004-03-19 PT PT04721905T patent/PT1608653E/pt unknown
- 2004-03-19 BR BRPI0408605-8A patent/BRPI0408605A/pt not_active IP Right Cessation
- 2004-03-19 SI SI200431223T patent/SI1608653T1/sl unknown
- 2004-03-19 MX MXPA05010112A patent/MXPA05010112A/es active IP Right Grant
- 2004-03-19 CN CNB2004800120101A patent/CN100368412C/zh not_active Expired - Fee Related
- 2004-03-19 DK DK04721905T patent/DK1608653T3/da active
- 2004-03-19 AR ARP040100918A patent/AR053082A1/es unknown
- 2004-03-19 EA EA200501311A patent/EA009198B1/ru not_active IP Right Cessation
- 2004-03-19 AT AT04721905T patent/ATE433977T1/de active
- 2004-03-19 ES ES04721905T patent/ES2328812T3/es not_active Expired - Lifetime
- 2004-03-19 WO PCT/EP2004/004013 patent/WO2004083210A1/en active Application Filing
-
2005
- 2005-09-01 IL IL170634A patent/IL170634A/en not_active IP Right Cessation
- 2005-09-13 US US11/224,873 patent/US7217715B2/en not_active Expired - Fee Related
- 2005-09-20 NO NO20054331A patent/NO20054331L/no not_active Application Discontinuation
-
2006
- 2006-07-25 HK HK06108282A patent/HK1088893A1/xx not_active IP Right Cessation
-
2007
- 2007-04-04 US US11/696,256 patent/US7393853B2/en not_active Expired - Fee Related
-
2009
- 2009-09-02 CY CY20091100926T patent/CY1109345T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1109345T1 (el) | ΠΑΡΑΓΩΓΑ ΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ 8-ΥΠΕΡΦΘΟΡΟΑΛΚΥΛΟ-6,7,8,9-ΤΕΤΡΑΫΔΡΟΠΥΡΙΜΙΔΟ (1,2-a) ΠΥΡΙΜΙΔΙΝ-4-ΟΝΗΣ | |
| HRP20070328T3 (en) | SUBSTITUTED 8'-PYRI(MI)DINYL-DIHYDROSPIRO-[CYCLOALKLYMINE]-PYRIMIDO[1,2a]PYRIMIDIN-6-ONE DERIVATIVES | |
| CY1109890T1 (el) | ΠΑΡΑΓΩΓΑ 8-ΥΠΟΚΑΤΕΣΤΗΜΕΝΗΣ-6,7,8,9- ΤΕΤΡΑΫΔΡΟΠΥΡΙΜΙΔΟ[1,2-α] ΠΥΡΙΜΙΔΙΝ-4-ΟΝΗΣ | |
| RS51654B (en) | DERIVATIVES OF THE SUBSTITUTED BICYCLIC PIRIMIDONE | |
| CY1120477T1 (el) | Ενεργοποιητης του υποδοχεα που ενεργοποιειται απο πολλαπλασιαστες των υπεροξεισωματων | |
| JO2925B1 (en) | New pyridine derivatives and pyrimidine derivatives (3) | |
| CY1117142T1 (el) | Παραγωγο αμινοπυραζολης | |
| CY1117157T1 (el) | Υποκατεστημενο παραγωγο ισοκινολινης | |
| MX2010008361A (es) | Derivados de arilamida oxazepinopirimidona sustituidos. | |
| MEP8409A (en) | Fused heterocyclic compound | |
| CY1111628T1 (el) | Υποκατεστημενες ενωσεις δικυκλολακταμης | |
| YU72804A (sh) | N-aril-2-oksazolidinon-5-karboksamidi i njihovi derivati i njihova primena kao antibakterijskih sredstava | |
| CY1115536T1 (el) | Νεες υδροξυ-6-ετεροαρυλφαινανθριδινες και χρηση αυτων ως αναστολεις pde4 | |
| EP1719763A4 (en) | NEW PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2) | |
| CY1111057T1 (el) | ΥΠΟΚΑΤΕΣΤΗΜΕΝΑ ΠΑΡΑΓΩΓΑ ΤΗΣ 8-ΠΥΡΙΔΙΝΥΛΟ-ΔΙΥΔΡΟΣΠΕΙΡΟ-ΚΥΚΛΟΑΛΚΥΛΟ-ΠΥΡΙΜΙΔΟ 1,2-a ΠΥΡΙΜΙΔΙΝ-6-ΟΝΗΣ ΚΑΙ ΤΗΣ 8-ΠΥΡΙΜΙΔΙΝΥΛΟ-ΔΙΥΔΡΟΣΠΕΙΡΟ-ΚΥΚΛΟΑΛΚΥΛΟ-ΠΥΡΙΜΙΔΟ 1,2-a ΠΥΡΙΜΙΔΙΝ-6- ΟΝΗΣ ΚΑΙ Η ΧΡΗΣΗ ΑΥΤΩΝ ΕΝΑΝΤΙ ΤΩΝ ΝΕΥΡΟΕΚΦΥΛΙΣΤΙΚΩΝ ΝΟΣΩΝ | |
| MX2009012377A (es) | Compuestos de arilamida pirimidona. | |
| EA200971061A1 (ru) | Пиримидоновые соединения гетероариламидов | |
| EA200971062A1 (ru) | Производные ариламидпиримидона | |
| WO2009095792A3 (en) | Substituted heteroarylamide diazepinopyrimidone derivatives | |
| CY1109283T1 (el) | Παραγωγα βαριολινης ως αντικαρκινικα μεσα | |
| MA32956B1 (fr) | Derives de 5-amino-2-(1-hydroxyethyl)-tetrahydropyrane | |
| WO2005011697A3 (en) | Sulfonamide derivatives with activity on protein kinase a and b | |
| NO20045123L (no) | Nitroserte imidazopyridiner | |
| DE60315626D1 (de) | Kondensierte bicyclische pyrimidinderivate | |
| DE60311000D1 (de) | Indolderivate und deren verwendung als 5-ht liganden |