CY1109246T1 - Μεθοδος ανιχνευσης συνδετη - Google Patents

Μεθοδος ανιχνευσης συνδετη

Info

Publication number
CY1109246T1
CY1109246T1 CY20091100763T CY091100763T CY1109246T1 CY 1109246 T1 CY1109246 T1 CY 1109246T1 CY 20091100763 T CY20091100763 T CY 20091100763T CY 091100763 T CY091100763 T CY 091100763T CY 1109246 T1 CY1109246 T1 CY 1109246T1
Authority
CY
Cyprus
Prior art keywords
nucleic acid
detecting
reagent complex
ligand
detection method
Prior art date
Application number
CY20091100763T
Other languages
Greek (el)
English (en)
Inventor
Frank Karlsen
Original Assignee
Norchip A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norchip A/S filed Critical Norchip A/S
Publication of CY1109246T1 publication Critical patent/CY1109246T1/el

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CY20091100763T 2000-12-05 2009-07-17 Μεθοδος ανιχνευσης συνδετη CY1109246T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0029617.8A GB0029617D0 (en) 2000-12-05 2000-12-05 Ligand detection method
EP01999671A EP1364057B1 (en) 2000-12-05 2001-12-05 Ligand detection method

Publications (1)

Publication Number Publication Date
CY1109246T1 true CY1109246T1 (el) 2014-07-02

Family

ID=9904463

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100763T CY1109246T1 (el) 2000-12-05 2009-07-17 Μεθοδος ανιχνευσης συνδετη

Country Status (14)

Country Link
US (1) US7910294B2 (cg-RX-API-DMAC10.html)
EP (1) EP1364057B1 (cg-RX-API-DMAC10.html)
JP (1) JP4266634B2 (cg-RX-API-DMAC10.html)
AR (1) AR031631A1 (cg-RX-API-DMAC10.html)
AT (1) ATE429510T1 (cg-RX-API-DMAC10.html)
AU (1) AU2002220898A1 (cg-RX-API-DMAC10.html)
CA (1) CA2437043C (cg-RX-API-DMAC10.html)
CY (1) CY1109246T1 (cg-RX-API-DMAC10.html)
DE (1) DE60138486D1 (cg-RX-API-DMAC10.html)
DK (1) DK1364057T3 (cg-RX-API-DMAC10.html)
ES (1) ES2324462T3 (cg-RX-API-DMAC10.html)
GB (2) GB0029617D0 (cg-RX-API-DMAC10.html)
PT (1) PT1364057E (cg-RX-API-DMAC10.html)
WO (1) WO2002046464A2 (cg-RX-API-DMAC10.html)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69940647D1 (de) 1998-05-01 2009-05-07 Gen Probe Inc Automatische diagnostische Analysevorrichtung
US8337753B2 (en) 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
EP1602733A1 (en) * 2004-06-02 2005-12-07 Keygene N.V. Detection of target nucleotide sequences using an asymmetric oligonucleotide ligation assay
JP5117722B2 (ja) 2003-09-02 2013-01-16 キージーン ナムローゼ フェンノートシャップ 標的核酸配列の検出のためのolaベースの方法
US20050214805A1 (en) * 2003-11-10 2005-09-29 Q-Rna, Inc. Methods of detection employing immuno-Q-Amp technology
US20060199194A1 (en) * 2003-11-10 2006-09-07 Q-Rna, Inc. Methods of detection using immuno-Q-Amp technology
WO2005054860A1 (en) * 2003-12-01 2005-06-16 Dako Denmark A/S Methods and compositions for immuno-histochemical detection
EP1921454B1 (en) * 2005-03-10 2015-08-12 Gen-Probe Incorporated Systems and methods to perform assays for detecting or quantifying analytes
US7794659B2 (en) * 2005-03-10 2010-09-14 Gen-Probe Incorporated Signal measuring system having a movable signal measuring device
DE102008062372B3 (de) * 2008-12-17 2010-06-17 Medizinische Hochschule Hannover Nachweiskonjugat und Verfahren zur Analyse
KR20130029128A (ko) 2010-07-23 2013-03-21 베크만 컬터, 인코포레이티드 실시간 pcr용 용기
US9046507B2 (en) 2010-07-29 2015-06-02 Gen-Probe Incorporated Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure
EP2678664B1 (en) 2011-02-24 2019-08-07 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
CN104040352B (zh) 2011-11-07 2016-09-07 贝克曼考尔特公司 机械臂
WO2013070755A2 (en) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Centrifuge system and workflow
EP3373015A1 (en) 2011-11-07 2018-09-12 Beckman Coulter Inc. Aliquotter system and workflow
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
US9910054B2 (en) 2011-11-07 2018-03-06 Beckman Coulter, Inc. System and method for processing samples
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
US9957553B2 (en) 2012-10-24 2018-05-01 Genmark Diagnostics, Inc. Integrated multiplex target analysis
CN107866286A (zh) 2013-03-15 2018-04-03 金马克诊断股份有限公司 用于操纵可变形流体容器的系统、方法和设备
CN107831324B (zh) 2013-03-15 2021-11-19 雅培制药有限公司 具有后面可进入轨道系统的自动化诊断分析仪及相关方法
CN105190317B (zh) 2013-03-15 2018-05-04 雅培制药有限公司 具有预处理转盘的诊断分析机及相关方法
CN105378487B (zh) 2013-03-15 2018-08-21 雅培制药有限公司 具有竖直布置的圆盘传送带的自动化诊断分析仪及相关方法
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
CN106932590A (zh) * 2015-12-31 2017-07-07 复旦大学 一种定量检测低丰度蛋白及其后修饰蛋白的方法
US10427162B2 (en) 2016-12-21 2019-10-01 Quandx Inc. Systems and methods for molecular diagnostics
WO2019200326A1 (en) 2018-04-13 2019-10-17 Rarecyte, Inc. Kits for labeling of biomarkers and methods of using the same
US20230138285A1 (en) * 2021-11-04 2023-05-04 Miltenyi Biotec B.V. & Co. KG Bright and releasable labels for cell staining based on the conjugates with several sites of fluorophore release

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656731A (en) * 1987-10-15 1997-08-12 Chiron Corporation Nucleic acid-amplified immunoassay probes
US6083689A (en) * 1990-10-16 2000-07-04 Bayer Corporation Sensitive immunoassays utilizing antibody conjugates with replicable DNA templates
WO1993001498A1 (en) * 1991-07-04 1993-01-21 Immunodex K/S Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone
US5665539A (en) * 1991-07-12 1997-09-09 The Regents Of The University Of California Immuno-polymerase chain reaction system for antigen detection
WO1994026932A1 (en) * 1993-05-13 1994-11-24 United States Of America, As Represented By The Secretary, Department Of Health And Human Services Nucleic acid tagged immunoassay
WO1995008626A1 (en) * 1993-09-20 1995-03-30 The Regents Of The University Of Colorado Strategy for the production of rna from immobilized templates
JP2909216B2 (ja) * 1994-04-29 1999-06-23 パーキン‐エルマー コーポレイション 核酸増幅生成物のリアルタイム検出装置
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
DE69734576T2 (de) * 1996-03-01 2006-08-03 E.I. Dupont De Nemours And Co., Wilmington Methode zur vervielfältigung und zum nachweis eines gewünschten nukleinsäurefragments
US6117631A (en) * 1996-10-29 2000-09-12 Polyprobe, Inc. Detection of antigens via oligonucleotide antibody conjugates
WO1998020148A1 (en) * 1996-11-04 1998-05-14 The Regents Of The University Of California Method for detection of pathogens in food
US6255060B1 (en) * 1996-11-21 2001-07-03 Trustees Of The University Of Pennsylvania Method of detecting protein by immuno RNA
US5922553A (en) * 1996-11-21 1999-07-13 Trustees Of The University Of Pennsylvania Method of detecting protein by immuno RNA
AT407160B (de) 1998-06-04 2001-01-25 Immuno Ag Verfahren zur bestimmung von antigenen
DE19915141C2 (de) * 1999-03-26 2002-11-21 Artus Ges Fuer Molekularbiolog Detektion von Nucleinsäure-Amplifikaten
EP1232283B1 (fr) 1999-10-27 2006-05-24 Université de Liège Immuno PCR en temps réel utilisant un ADN-chimère comme marqueur d'amplification

Also Published As

Publication number Publication date
GB0029617D0 (en) 2001-01-17
ATE429510T1 (de) 2009-05-15
AR031631A1 (es) 2003-09-24
EP1364057B1 (en) 2009-04-22
WO2002046464A3 (en) 2003-09-12
GB0129143D0 (en) 2002-01-23
AU2002220898A1 (en) 2002-06-18
PT1364057E (pt) 2009-07-06
GB2375822A (en) 2002-11-27
US20040076983A1 (en) 2004-04-22
CA2437043A1 (en) 2002-06-13
JP2004520574A (ja) 2004-07-08
WO2002046464A2 (en) 2002-06-13
DK1364057T3 (da) 2009-08-03
EP1364057A2 (en) 2003-11-26
GB2375822B (en) 2005-04-06
ES2324462T3 (es) 2009-08-07
CA2437043C (en) 2011-10-11
US7910294B2 (en) 2011-03-22
JP4266634B2 (ja) 2009-05-20
DE60138486D1 (de) 2009-06-04

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