CY1108605T1 - Αλλαντοτοξινη στην θεραπεια ή στην προληψη της ακμης - Google Patents
Αλλαντοτοξινη στην θεραπεια ή στην προληψη της ακμηςInfo
- Publication number
- CY1108605T1 CY1108605T1 CY20081101377T CY081101377T CY1108605T1 CY 1108605 T1 CY1108605 T1 CY 1108605T1 CY 20081101377 T CY20081101377 T CY 20081101377T CY 081101377 T CY081101377 T CY 081101377T CY 1108605 T1 CY1108605 T1 CY 1108605T1
- Authority
- CY
- Cyprus
- Prior art keywords
- allantotoxin
- acne
- acme
- prevention
- treatment
- Prior art date
Links
- 230000002265 prevention Effects 0.000 title 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 2
- 206010000496 acne Diseases 0.000 abstract 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 abstract 1
- 108030001720 Bontoxilysin Proteins 0.000 abstract 1
- 229960000458 allantoin Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229940053031 botulinum toxin Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000002510 keratinocyte Anatomy 0.000 abstract 1
- 230000001734 parasympathetic effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 210000000106 sweat gland Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Η Αλλαντοτοξίνη μπορεί να χρησιμοποιηθεί ώστε να αναστείλει τον καταρράκτη γεγονότων που οδηγούν στην ακμή. Τα αποτελέσματα των προκαταρκτικών μελετών είναι δραματικά. Χωρίς να επιθυμούμε δέσμευση σε αυτή τη θεωρία, πιστεύεται ότι ή αλλαντοτοξίνη, επιτυγχάνει αυτό το αποτέλεσμα μέσω παρασυμπαθητικών δράσεων, αναστέλλοντας την δραστηριότητα του ιδρωτοποιού αδένα, διειγείτοντας την κινητοποίηση των κερατινοκυττάρων, μέσω αντί-φλεγμονωδών και πιθανών αντιανδρογονικών δράσεων. Η αλλαντοτοξίνη μπορεί να διαδραματίσει ένα σημαντικό ρόλο στην ελάττωση και συχνά στην πρόληψη του σχηματισμού ακμής.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30820501P | 2001-07-27 | 2001-07-27 | |
EP02791543A EP1411978B1 (en) | 2001-07-27 | 2002-07-25 | Botulinum toxin in the treatment or prevention of acne |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108605T1 true CY1108605T1 (el) | 2014-04-09 |
Family
ID=23192997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081101377T CY1108605T1 (el) | 2001-07-27 | 2008-11-27 | Αλλαντοτοξινη στην θεραπεια ή στην προληψη της ακμης |
Country Status (15)
Country | Link |
---|---|
US (1) | US7226605B2 (el) |
EP (1) | EP1411978B1 (el) |
JP (1) | JP4138651B2 (el) |
KR (1) | KR100602308B1 (el) |
CN (1) | CN1258381C (el) |
AT (1) | ATE406910T1 (el) |
AU (1) | AU2002355730B2 (el) |
CA (1) | CA2451923C (el) |
CY (1) | CY1108605T1 (el) |
DE (1) | DE60228723D1 (el) |
DK (1) | DK1411978T3 (el) |
ES (1) | ES2312651T3 (el) |
NZ (1) | NZ531389A (el) |
PT (1) | PT1411978E (el) |
WO (1) | WO2003011333A1 (el) |
Families Citing this family (65)
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US7838008B2 (en) | 1999-12-07 | 2010-11-23 | Allergan, Inc. | Methods for treating diverse cancers |
US20030113349A1 (en) | 2001-12-18 | 2003-06-19 | Coleman William P. | Topically applied clostridium botulinum toxin compositions and treatment methods |
US7763663B2 (en) * | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
US7022329B2 (en) * | 2002-02-25 | 2006-04-04 | Allergan, Inc. | Method for treating neurogenic inflammation pain with botulinum toxin and substance P components |
EP2272340B1 (en) | 2002-08-19 | 2018-03-14 | Ira Sanders | Botulinum toxin |
US20120114697A1 (en) | 2002-08-19 | 2012-05-10 | Ira Sanders | Treatment of holocrine gland dysfunction with clostridia neurotoxins |
US7824693B2 (en) * | 2002-08-19 | 2010-11-02 | Ira Sanders | Treatment of fine wrinkles with clostridia neurotoxins |
US7666435B2 (en) * | 2002-08-19 | 2010-02-23 | Ira Sanders | Treatment of fine wrinkles with clostridia neurotoxins |
JP2007528351A (ja) * | 2003-03-06 | 2007-10-11 | ボツリヌム・トクシン・リサーチ・アソシエイツ・インコーポレイテッド | 慢性の霰粒腫および麦粒腫のボツリヌス毒素による治療 |
US8734810B2 (en) | 2003-10-29 | 2014-05-27 | Allergan, Inc. | Botulinum toxin treatments of neurological and neuropsychiatric disorders |
GB0328060D0 (en) | 2003-12-04 | 2004-01-07 | Sod Conseils Rech Applic | Botulinum toxin treatment |
US8871224B2 (en) | 2003-12-09 | 2014-10-28 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
US8048423B2 (en) * | 2003-12-09 | 2011-11-01 | Allergan, Inc. | Botulinum toxin therapy for skin disorders |
US20050191321A1 (en) | 2004-02-26 | 2005-09-01 | Allergan, Inc. | Methods for treating headache |
US9078892B2 (en) | 2004-02-26 | 2015-07-14 | Allergan, Inc. | Methods for treating pain and for treating a medication overuse disorder |
US20100266638A1 (en) | 2004-02-26 | 2010-10-21 | Allergan, Inc. | Headache treatment method |
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EP1729821B1 (en) * | 2004-03-03 | 2013-07-17 | ReVance Therapeutics, Inc. | Compositions and methods for topical application and transdermal delivery of botulinum toxins |
CA3031270A1 (en) | 2004-03-03 | 2005-12-22 | Revance Therapeutics, Inc. | Compositions and methods for topical diagnostic and therapeutic transport |
US20050220821A1 (en) | 2004-03-31 | 2005-10-06 | Allergan, Inc. | Pressure sore treatment |
US20050220734A1 (en) * | 2004-04-02 | 2005-10-06 | Allergan, Inc. | Therapy for melanin related afflictions |
US6991789B2 (en) | 2004-06-29 | 2006-01-31 | Allergas, Inc. | Methods of modulating intracellular degradation rates of toxins |
US7429386B2 (en) | 2004-09-03 | 2008-09-30 | Allergan, Inc. | Stretch mark treatment |
US7179474B2 (en) | 2004-09-03 | 2007-02-20 | Allergan, Inc. | Methods for treating a buttock deformity |
US7897147B2 (en) | 2004-10-20 | 2011-03-01 | Allergan, Inc. | Treatment of premenstrual disorders |
US7655244B2 (en) | 2005-02-01 | 2010-02-02 | Allergan, Inc. | Targeted delivery of botulinum toxin for the treatment and prevention of trigeminal autonomic cephalgias, migraine and vascular conditions |
US7749515B2 (en) | 2005-02-01 | 2010-07-06 | Allergan, Inc. | Targeted delivery of botulinum toxin to the sphenopalatine ganglion |
RU2007136616A (ru) | 2005-03-03 | 2009-04-10 | Риванс Терапьютикс, Инк. (Us) | Композиция и способ для местного применения и чрескожного введения ботулинового токсина |
US7419675B2 (en) | 2005-05-26 | 2008-09-02 | Allergan, Inc. | Method for treating peritoneal adhesions |
BRPI0613631A8 (pt) * | 2005-07-18 | 2017-12-26 | Univ Massachusetts Lowell | nanoemulsão e método, |
US8318181B2 (en) | 2005-12-01 | 2012-11-27 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
US7824694B2 (en) | 2006-01-12 | 2010-11-02 | Allergan, Inc. | Methods for enhancing therapeutic effects of a neurotoxin |
CN101074935B (zh) * | 2006-05-19 | 2011-03-23 | 清华大学 | 探测器阵列及设备 |
US10792344B2 (en) | 2006-06-29 | 2020-10-06 | Merz Pharma Gmbh & Co. Kgaa | High frequency application of botulinum toxin therapy |
AR061669A1 (es) * | 2006-06-29 | 2008-09-10 | Merz Pharma Gmbh & Co Kgaa | Aplicacion de alta frecuencia de terapia con toxina botulinica |
US9061025B2 (en) | 2006-08-31 | 2015-06-23 | Allergan, Inc. | Methods for selecting headache patients responsive to botulinum toxin therapy |
CN101848702B (zh) | 2006-12-01 | 2013-07-17 | 安特里奥公司 | 两亲实体纳米粒子 |
KR101518077B1 (ko) | 2006-12-01 | 2015-05-28 | 안테리오스, 인코퍼레이티드 | 펩티드 나노입자 및 이의 용도 |
CN101583274A (zh) * | 2006-12-29 | 2009-11-18 | 雷文斯治疗公司 | 使用反向序列hiv-tat多肽的运输分子 |
AU2007340162B2 (en) * | 2006-12-29 | 2013-08-01 | Revance Therapeutics, Inc. | Compositions and methods of topical application and transdermal delivery of botulinum toxins stabilized with polypeptide fragments derived from HIV-TAT |
ES2660906T3 (es) | 2007-05-31 | 2018-03-26 | Anterios, Inc. | Nanopartículas de ácido nucleico y usos de las mismas |
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CA2774951C (en) | 2009-09-24 | 2014-12-16 | Allergan, Inc. | Method of treating osteoporosis with a neurotoxin |
US8697090B2 (en) | 2011-05-05 | 2014-04-15 | Allergan, Inc. | Method of treating persistent genital arousal disorder with a neurotoxin |
ES2424294B1 (es) | 2012-03-22 | 2014-07-21 | Lipotec, S.A. | Exopolisacárido para el tratamiento y/o cuidado de la piel, mucosas, cabello y/o uñas |
US10035820B2 (en) | 2012-04-13 | 2018-07-31 | Lubrizol Advanced Materials, Inc | Compounds which inhibit neuronal exocytosis |
EP2649983A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (II) |
EP2649985A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis (III) |
EP2649984A1 (en) | 2012-04-13 | 2013-10-16 | Lipotec, S.A. | Compounds which inhibit neuronal exocytosis |
CN105451710A (zh) | 2013-03-22 | 2016-03-30 | 利普泰股份公司 | 用于治疗和/或护理皮肤、粘膜和/或指甲的外泌多糖 |
US9480731B2 (en) | 2013-12-12 | 2016-11-01 | Medy-Tox, Inc. | Long lasting effect of new botulinum toxin formulations |
US9649266B2 (en) | 2014-05-01 | 2017-05-16 | Anterios, Inc. | Methods to treat, prevent, and improve skin conditions |
WO2015168562A1 (en) * | 2014-05-01 | 2015-11-05 | Anterios, Inc. | Demonstrable efficacy across or within patient populations |
WO2016154020A1 (en) * | 2015-03-20 | 2016-09-29 | The Regents Of The University Of California | Methods for reducing sebum production and/or excretion |
WO2018038301A1 (en) | 2016-08-26 | 2018-03-01 | Hugel Inc. | Stabilized liquid formulation of botulinum toxin and preparation method thereof |
JP2019535829A (ja) | 2016-11-21 | 2019-12-12 | エイリオン セラピューティクス, インコーポレイテッド | 大型薬剤の経皮送達 |
EP3470054B1 (en) | 2017-10-11 | 2023-09-20 | Hugel Inc. | Microstructure formulation techniques for botulinum toxin |
US10792400B2 (en) | 2017-10-12 | 2020-10-06 | Hugel Inc. | Microstructure formulation techniques for botulinum toxin |
US10525111B2 (en) | 2017-10-12 | 2020-01-07 | Hugel, Inc. | Microstructure formulation techniques for botulinum toxin |
EP3728295A1 (en) * | 2017-12-20 | 2020-10-28 | Allergan, Inc. | Botulinum toxin cell binding domain polypeptides and methods of use for treatments of fibrosis associated disorders |
WO2019226599A1 (en) * | 2018-05-22 | 2019-11-28 | Alkalidx, Inc. | Diagnostics and treatments of anesthetic insensitive subjects |
US11191819B2 (en) | 2018-08-28 | 2021-12-07 | Ira Sanders | Skin therapeutics |
EP3660509B1 (en) | 2018-11-29 | 2022-03-09 | Hugel Inc. | A cell-based method for determining an activity of botulinum toxin |
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US5766605A (en) * | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
US5670484A (en) * | 1994-05-09 | 1997-09-23 | Binder; William J. | Method for treatment of skin lesions associated with cutaneous cell-proliferative disorders |
JPH11501517A (ja) * | 1995-03-16 | 1999-02-09 | クノル アクチエンゲゼルシャフト | 細胞を製出するためおよび創傷治療用の定義された新規酵素混合物 |
KR20010089347A (ko) * | 1998-10-27 | 2001-10-06 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 상처 치료 증진 방법 |
AUPQ899700A0 (en) * | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
US7255865B2 (en) * | 2000-12-05 | 2007-08-14 | Allergan, Inc. | Methods of administering botulinum toxin |
US20020086036A1 (en) * | 2000-12-05 | 2002-07-04 | Allergan Sales, Inc. | Methods for treating hyperhidrosis |
US20030021775A1 (en) * | 2001-07-27 | 2003-01-30 | Ramot University Authority For Applied Research & Industrial Development Ltd. | Device for and method of controlled enzymatic removal and retrieval of tissue |
US20030113349A1 (en) * | 2001-12-18 | 2003-06-19 | Coleman William P. | Topically applied clostridium botulinum toxin compositions and treatment methods |
EP2272340B1 (en) * | 2002-08-19 | 2018-03-14 | Ira Sanders | Botulinum toxin |
-
2002
- 2002-07-25 AT AT02791543T patent/ATE406910T1/de active
- 2002-07-25 DE DE60228723T patent/DE60228723D1/de not_active Expired - Lifetime
- 2002-07-25 US US10/483,154 patent/US7226605B2/en not_active Expired - Fee Related
- 2002-07-25 PT PT02791543T patent/PT1411978E/pt unknown
- 2002-07-25 CA CA002451923A patent/CA2451923C/en not_active Expired - Fee Related
- 2002-07-25 EP EP02791543A patent/EP1411978B1/en not_active Expired - Lifetime
- 2002-07-25 WO PCT/US2002/023670 patent/WO2003011333A1/en active IP Right Grant
- 2002-07-25 AU AU2002355730A patent/AU2002355730B2/en not_active Ceased
- 2002-07-25 CN CNB028162455A patent/CN1258381C/zh not_active Expired - Fee Related
- 2002-07-25 KR KR1020047000835A patent/KR100602308B1/ko not_active IP Right Cessation
- 2002-07-25 ES ES02791543T patent/ES2312651T3/es not_active Expired - Lifetime
- 2002-07-25 NZ NZ531389A patent/NZ531389A/en not_active IP Right Cessation
- 2002-07-25 JP JP2003516563A patent/JP4138651B2/ja not_active Expired - Fee Related
- 2002-07-25 DK DK02791543T patent/DK1411978T3/da active
-
2008
- 2008-11-27 CY CY20081101377T patent/CY1108605T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE406910T1 (de) | 2008-09-15 |
KR100602308B1 (ko) | 2006-07-18 |
US20050074466A1 (en) | 2005-04-07 |
KR20040030820A (ko) | 2004-04-09 |
EP1411978A1 (en) | 2004-04-28 |
WO2003011333A1 (en) | 2003-02-13 |
DE60228723D1 (de) | 2008-10-16 |
PT1411978E (pt) | 2008-11-28 |
CN1543354A (zh) | 2004-11-03 |
CN1258381C (zh) | 2006-06-07 |
CA2451923C (en) | 2009-10-20 |
AU2002355730B2 (en) | 2007-09-13 |
JP2004538310A (ja) | 2004-12-24 |
US7226605B2 (en) | 2007-06-05 |
NZ531389A (en) | 2005-08-26 |
EP1411978B1 (en) | 2008-09-03 |
JP4138651B2 (ja) | 2008-08-27 |
DK1411978T3 (da) | 2009-01-05 |
CA2451923A1 (en) | 2003-02-13 |
ES2312651T3 (es) | 2009-03-01 |
EP1411978A4 (en) | 2005-08-17 |
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