CY1108292T1 - Αντικαρκινικο σκευασμα που περιεχει dmxaa - Google Patents
Αντικαρκινικο σκευασμα που περιεχει dmxaaInfo
- Publication number
- CY1108292T1 CY1108292T1 CY20081100909T CY081100909T CY1108292T1 CY 1108292 T1 CY1108292 T1 CY 1108292T1 CY 20081100909 T CY20081100909 T CY 20081100909T CY 081100909 T CY081100909 T CY 081100909T CY 1108292 T1 CY1108292 T1 CY 1108292T1
- Authority
- CY
- Cyprus
- Prior art keywords
- dmxaa
- cancer
- compounds
- container
- acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Physiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Portable Nailing Machines And Staplers (AREA)
- Control Of Eletrric Generators (AREA)
- Fittings On The Vehicle Exterior For Carrying Loads, And Devices For Holding Or Mounting Articles (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0225508A GB2394658A (en) | 2002-11-01 | 2002-11-01 | Oral anti-cancer composition |
| EP03773835A EP1572194B1 (en) | 2002-11-01 | 2003-10-30 | Anti-cancer composition comprising dmxaa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1108292T1 true CY1108292T1 (el) | 2014-02-12 |
Family
ID=9947036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081100909T CY1108292T1 (el) | 2002-11-01 | 2008-08-25 | Αντικαρκινικο σκευασμα που περιεχει dmxaa |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7585893B2 (https=) |
| EP (1) | EP1572194B1 (https=) |
| JP (1) | JP2006508091A (https=) |
| AT (1) | ATE401882T1 (https=) |
| AU (1) | AU2003282215A1 (https=) |
| CY (1) | CY1108292T1 (https=) |
| DE (1) | DE60322425D1 (https=) |
| DK (1) | DK1572194T3 (https=) |
| ES (1) | ES2311740T3 (https=) |
| GB (1) | GB2394658A (https=) |
| PT (1) | PT1572194E (https=) |
| SI (1) | SI1572194T1 (https=) |
| WO (1) | WO2004039363A1 (https=) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000076497A1 (en) * | 1999-06-14 | 2000-12-21 | Cancer Research Ventures Limited | Cancer therapy |
| WO2002009700A1 (en) | 2000-07-28 | 2002-02-07 | Cancer Research Technology Limited | Cancer treatment by combination therapy |
| GB0121285D0 (en) | 2001-09-03 | 2001-10-24 | Cancer Res Ventures Ltd | Anti-cancer combinations |
| GB2386836B (en) * | 2002-03-22 | 2006-07-26 | Cancer Res Ventures Ltd | Anti-cancer combinations |
| GB2394658A (en) | 2002-11-01 | 2004-05-05 | Cancer Rec Tech Ltd | Oral anti-cancer composition |
| GB0321999D0 (en) * | 2003-09-19 | 2003-10-22 | Cancer Rec Tech Ltd | Anti-cancer combinations |
| EP2275110B1 (en) * | 2004-12-22 | 2013-07-10 | Merck Serono SA | Cladribine regimen for treating Multiple Sclerosis |
| US20100297112A1 (en) * | 2005-08-26 | 2010-11-25 | Antisoma Research Limited | Combinations comprising dmxaa for the treatment of cancer |
| JP5713377B2 (ja) | 2005-12-28 | 2015-05-07 | ザ スクリプス リサーチ インスティテュート | 薬物標的としての天然アンチセンスおよび非コードｒｎａ転写物 |
| WO2007135172A2 (en) | 2006-05-24 | 2007-11-29 | Laboratoires Serono S.A. | Cladribine regimen for treating multiple sclerosis |
| US8592221B2 (en) | 2007-04-19 | 2013-11-26 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| CN102239260B (zh) | 2008-10-03 | 2017-04-12 | 库尔纳公司 | 通过抑制针对载脂蛋白‑a1的天然反义转录物治疗载脂蛋白‑a1相关疾病 |
| US20110201678A1 (en) * | 2008-10-17 | 2011-08-18 | Masse Craig E | Xanthenone-4-Acetic Acid Derivatives |
| ES2629630T3 (es) | 2008-12-04 | 2017-08-11 | Curna, Inc. | Tratamiento de enfermedades relacionadas con eritropoyetina (EPO) mediante inhibición del transcrito antisentido natural a EPO |
| US20110294870A1 (en) | 2008-12-04 | 2011-12-01 | Opko Curna, Llc | Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene |
| ES2600781T3 (es) | 2008-12-04 | 2017-02-10 | Curna, Inc. | Tratamiento para enfermedades relacionadas con el factor de crecimiento del endotelio vascular (vegf) mediante la inhibición de transcritos antisentido naturales de vegf |
| ES2762610T3 (es) | 2009-02-12 | 2020-05-25 | Curna Inc | Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF |
| CN102482677B (zh) | 2009-03-16 | 2017-10-17 | 库尔纳公司 | 通过抑制nrf2的天然反义转录物治疗核因子(红细胞衍生2)‑样2(nrf2)相关疾病 |
| WO2010107740A2 (en) | 2009-03-17 | 2010-09-23 | Curna, Inc. | Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1 |
| ES2609655T3 (es) | 2009-05-06 | 2017-04-21 | Curna, Inc. | Tratamiento de enfermedades relacionadas con tristetraprolina (TTP) mediante inhibición de transcrito antisentido natural para TTP |
| CN103223177B (zh) | 2009-05-06 | 2016-08-10 | 库尔纳公司 | 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病 |
| JP5931720B2 (ja) | 2009-05-08 | 2016-06-08 | クルナ・インコーポレーテッド | Ｄｍｄファミリーに対する天然アンチセンス転写物の抑制によるジストロフィンファミリー関連疾患の治療 |
| DK2432881T3 (en) | 2009-05-18 | 2018-02-26 | Curna Inc | TREATMENT OF REPROGRAMMING FACTOR-RELATED DISEASES BY INHIBITING NATURAL ANTISENSE TRANSCRIPTS TO A REPROGRAMMING FACTOR |
| CA2762987A1 (en) | 2009-05-22 | 2010-11-25 | Joseph Collard | Treatment of transcription factor e3 (tfe3) and insulin receptor substrate 2 (irs2) related diseases by inhibition of natural antisense transcript to tfe3 |
| KR101704988B1 (ko) | 2009-05-28 | 2017-02-08 | 큐알엔에이, 인크. | 항바이러스 유전자에 대한 천연 안티센스 전사체의 억제에 의한 항바이러스 유전자 관련된 질환의 치료 |
| US8951981B2 (en) | 2009-06-16 | 2015-02-10 | Curna, Inc. | Treatment of paraoxonase 1 (PON1) related diseases by inhibition of natural antisense transcript to PON1 |
| WO2010148050A2 (en) | 2009-06-16 | 2010-12-23 | Curna, Inc. | Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene |
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| EP2446037B1 (en) | 2009-06-26 | 2016-04-20 | CuRNA, Inc. | Treatment of down syndrome gene related diseases by inhibition of natural antisense transcript to a down syndrome gene |
| CN102712925B (zh) | 2009-07-24 | 2017-10-27 | 库尔纳公司 | 通过抑制sirtuin(sirt)的天然反义转录物来治疗sirtuin(sirt)相关性疾病 |
| CN102762731B (zh) | 2009-08-05 | 2018-06-22 | 库尔纳公司 | 通过抑制针对胰岛素基因(ins)的天然反义转录物来治疗胰岛素基因(ins)相关的疾病 |
| CN104313027B (zh) | 2009-08-11 | 2018-11-20 | 库尔纳公司 | 通过抑制脂连蛋白(adipoq)的天然反义转录物治疗脂连蛋白(adipoq)相关疾病 |
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| RU2619185C2 (ru) | 2009-12-23 | 2017-05-12 | Курна, Инк. | Лечение заболеваний, связанных с разобщающим белком 2 (ucp2), путем ингибирования природного антисмыслового транскрипта к ucp2 |
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| JP2002523378A (ja) | 1998-08-24 | 2002-07-30 | マキシム ファーマシューティカルズ インコーポレイテッド | Ｈ２−レセプターアゴニストおよび他のｔ−細胞活性化薬剤を用いたｔ−細胞（ｃｄ４＋およびｃｄ８＋）の活性化および保護 |
| AUPP609198A0 (en) | 1998-09-22 | 1998-10-15 | Curtin University Of Technology | Use of non-peptidyl compounds for the treatment of insulin related ailments |
| US6174873B1 (en) * | 1998-11-04 | 2001-01-16 | Supergen, Inc. | Oral administration of adenosine analogs |
| GB9903404D0 (en) | 1999-02-16 | 1999-04-07 | Angiogene Pharm Ltd | Methods of treatment and compositions useful for the treatment of diseases involving angiogenesis |
| PT1033364E (pt) * | 1999-03-01 | 2005-07-29 | Pfizer Prod Inc | Ciano com acidos oxamicos e derivados como ligandos de receptores de tiroide |
| WO2000076497A1 (en) | 1999-06-14 | 2000-12-21 | Cancer Research Ventures Limited | Cancer therapy |
| US6806257B1 (en) | 1999-10-20 | 2004-10-19 | Board Of Trustees Of Southern Illinois University | Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators |
| WO2001034137A2 (en) | 1999-11-11 | 2001-05-17 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
| WO2001034135A2 (en) | 1999-11-11 | 2001-05-17 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
| WO2001034197A2 (en) | 1999-11-11 | 2001-05-17 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
| WO2001034198A2 (en) | 1999-11-11 | 2001-05-17 | Eli Lilly And Company | Oncolytic combinations for the treatment of cancer |
| JP2003522790A (ja) | 2000-02-17 | 2003-07-29 | メルク エンド カムパニー インコーポレーテッド | Ｃｏｘ−２選択的阻害薬を用いた前立腺癌の治療または予防 |
| JP2001247459A (ja) | 2000-03-03 | 2001-09-11 | Oakland Uniservices Ltd | 癌の組み合わせ療法 |
| WO2002009700A1 (en) | 2000-07-28 | 2002-02-07 | Cancer Research Technology Limited | Cancer treatment by combination therapy |
| GB0121285D0 (en) | 2001-09-03 | 2001-10-24 | Cancer Res Ventures Ltd | Anti-cancer combinations |
| GB2386836B (en) | 2002-03-22 | 2006-07-26 | Cancer Res Ventures Ltd | Anti-cancer combinations |
| GB2394658A (en) | 2002-11-01 | 2004-05-05 | Cancer Rec Tech Ltd | Oral anti-cancer composition |
| GB0321999D0 (en) | 2003-09-19 | 2003-10-22 | Cancer Rec Tech Ltd | Anti-cancer combinations |
| US20100297112A1 (en) | 2005-08-26 | 2010-11-25 | Antisoma Research Limited | Combinations comprising dmxaa for the treatment of cancer |
| GB0517387D0 (en) | 2005-08-26 | 2005-10-05 | Antisoma Res Ltd | Combinations for the treatment of cancer |
-
2002
- 2002-11-01 GB GB0225508A patent/GB2394658A/en not_active Withdrawn
-
2003
- 2003-10-30 EP EP03773835A patent/EP1572194B1/en not_active Expired - Lifetime
- 2003-10-30 WO PCT/GB2003/004688 patent/WO2004039363A1/en not_active Ceased
- 2003-10-30 AU AU2003282215A patent/AU2003282215A1/en not_active Abandoned
- 2003-10-30 PT PT03773835T patent/PT1572194E/pt unknown
- 2003-10-30 JP JP2004547801A patent/JP2006508091A/ja active Pending
- 2003-10-30 DK DK03773835T patent/DK1572194T3/da active
- 2003-10-30 ES ES03773835T patent/ES2311740T3/es not_active Expired - Lifetime
- 2003-10-30 DE DE60322425T patent/DE60322425D1/de not_active Expired - Lifetime
- 2003-10-30 AT AT03773835T patent/ATE401882T1/de active
- 2003-10-30 SI SI200331387T patent/SI1572194T1/sl unknown
-
2005
- 2005-04-28 US US11/116,798 patent/US7585893B2/en not_active Expired - Fee Related
-
2008
- 2008-08-25 CY CY20081100909T patent/CY1108292T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1572194E (pt) | 2008-11-03 |
| EP1572194B1 (en) | 2008-07-23 |
| WO2004039363A1 (en) | 2004-05-13 |
| ATE401882T1 (de) | 2008-08-15 |
| ES2311740T3 (es) | 2009-02-16 |
| DK1572194T3 (da) | 2008-08-25 |
| SI1572194T1 (sl) | 2008-12-31 |
| GB2394658A (en) | 2004-05-05 |
| US20060009505A1 (en) | 2006-01-12 |
| AU2003282215A1 (en) | 2004-05-25 |
| US7585893B2 (en) | 2009-09-08 |
| DE60322425D1 (de) | 2008-09-04 |
| JP2006508091A (ja) | 2006-03-09 |
| GB0225508D0 (en) | 2002-12-11 |
| EP1572194A1 (en) | 2005-09-14 |
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