CY1105992T1 - Σ-μεθυλ-διυδρο-ζιπρασιδονη για τη θepαπευτικη αγωγη ψυχιατρικων διαταραχων - Google Patents
Σ-μεθυλ-διυδρο-ζιπρασιδονη για τη θepαπευτικη αγωγη ψυχιατρικων διαταραχωνInfo
- Publication number
- CY1105992T1 CY1105992T1 CY20071100161T CY071100161T CY1105992T1 CY 1105992 T1 CY1105992 T1 CY 1105992T1 CY 20071100161 T CY20071100161 T CY 20071100161T CY 071100161 T CY071100161 T CY 071100161T CY 1105992 T1 CY1105992 T1 CY 1105992T1
- Authority
- CY
- Cyprus
- Prior art keywords
- disorder
- disorders
- anxiety
- treatment
- psychotic
- Prior art date
Links
- NHUDBVVEHOSVCD-UHFFFAOYSA-N 6-chloro-5-[2-[4-(2-methylsulfanylbenzenecarboximidoyl)piperazin-1-yl]ethyl]-1,3-dihydroindol-2-one Chemical compound CSC1=CC=CC=C1C(=N)N1CCN(CCC=2C(=CC=3NC(=O)CC=3C=2)Cl)CC1 NHUDBVVEHOSVCD-UHFFFAOYSA-N 0.000 title abstract 2
- 208000020016 psychiatric disease Diseases 0.000 title abstract 2
- 208000028017 Psychotic disease Diseases 0.000 abstract 4
- 208000019901 Anxiety disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000020925 Bipolar disease Diseases 0.000 abstract 2
- 206010012289 Dementia Diseases 0.000 abstract 2
- 208000019022 Mood disease Diseases 0.000 abstract 2
- 230000036506 anxiety Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 201000000980 schizophrenia Diseases 0.000 abstract 2
- 208000008811 Agoraphobia Diseases 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000020706 Autistic disease Diseases 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 208000012661 Dyskinesia Diseases 0.000 abstract 1
- 206010014557 Emotional poverty Diseases 0.000 abstract 1
- 208000011688 Generalised anxiety disease Diseases 0.000 abstract 1
- 206010026749 Mania Diseases 0.000 abstract 1
- 208000036626 Mental retardation Diseases 0.000 abstract 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
- 206010041243 Social avoidant behaviour Diseases 0.000 abstract 1
- 206010041250 Social phobia Diseases 0.000 abstract 1
- 208000000323 Tourette Syndrome Diseases 0.000 abstract 1
- 208000016620 Tourette disease Diseases 0.000 abstract 1
- 230000016571 aggressive behavior Effects 0.000 abstract 1
- 238000013019 agitation Methods 0.000 abstract 1
- 230000003542 behavioural effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000029364 generalized anxiety disease Diseases 0.000 abstract 1
- 208000024714 major depressive disease Diseases 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
- 208000019906 panic disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000019899 phobic disease Diseases 0.000 abstract 1
- 208000028173 post-traumatic stress disease Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Abstract
Η παρούσα εφεύρεση αναφέρεται σε φαρμακευτικές συνθέσεις περιέχουσες S-μεθυλ-διυδρο-ζιπρασιδόνη και στη χρήση μιας τέτοιας ένωσης και των φαρμακευτικώς αποδεκτών αλάτων αυτής για τη θεραπευτική αγωγή ψυχιατρικών διαταραχών. Ειδικότερα, αναφέρεται στη χρήση μιας τέτοιας ένωσης και των φαρμακευτικώς αποδεκτών αλάτων αυτής για τη θεραπευτική αγωγή μιας διαταραχής ή κατάστασης που επιλέγεται από: σχιζοφρένεια, διαταραχές άγχους όπως διαταραχή γενικευμένου άγχους, διαταραχή πανικού, διαταραχή μετατραυματικού στρες και φοβίες (π.χ., κοινωνική φοβία, αγοραφοβία κ.λ.π)˙ ψυχωτικά επεισόδια άγχους: άγχος, ταραχή, υπέρμετρη επιθετικότητα, ένταση, ή κοινωνική ή συναισθηματική απόσυρση συνδεόμενη με ψύχωση· διαταραχή της διάθεσης με ψυχωτικά στοιχεία όπως δριμεία μείζονα καταθλιπτική διαταραχή· διαταραχές της διάθεσης συνδεόμενες με ψυχωτικές διαταραχές όπως οξεία μανία και κατάθλιψη συνδεόμενη με διπολική διαταραχή, και διαταραχές της διάθεσης συνδεόμενες με σχιζοφρένεια· συμπεριφορικές διαταραχές συνδεόμενες με νοητική υστέρηση, αυτιστική διαταραχή, και διαταραχή επαφής· άνοιες όπως άνοιες συνδεόμενες με νόσο του Alzheimer˙ προκαλούμενες από φάρμακο και βασιζόμενες σε νευροεκφυλισμό δυσκινησίες· ψυχαναγκαστική καταναγκαστική διαταραχή· και σύνδρομο του Tourette.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20913600P | 2000-06-02 | 2000-06-02 | |
US21217200P | 2000-06-16 | 2000-06-16 | |
EP01932011A EP1286672B1 (en) | 2000-06-02 | 2001-05-28 | S-methyl-dihydro-ziprasidone for the treatment of ocular disorders. |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1105992T1 true CY1105992T1 (el) | 2011-04-06 |
Family
ID=26903852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20071100161T CY1105992T1 (el) | 2000-06-02 | 2007-02-08 | Σ-μεθυλ-διυδρο-ζιπρασιδονη για τη θepαπευτικη αγωγη ψυχιατρικων διαταραχων |
Country Status (44)
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004054487A2 (en) | 2002-12-13 | 2004-07-01 | Regents Of The University Of Minnesota | Scleral depressor |
US7667037B2 (en) | 2003-10-24 | 2010-02-23 | Teva Pharmaceutical Industries Ltd. | Processes for preparation of ziprasidone |
ES2250001B1 (es) * | 2004-09-29 | 2007-06-01 | Medichem, S.A. | Proceso para la purificacion de ziprasidona. |
JP2012174228A (ja) * | 2011-02-24 | 2012-09-10 | Kyocera Corp | プログラム保護装置および通信装置 |
EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
US9981041B2 (en) * | 2016-08-23 | 2018-05-29 | Ira Jason Salzman | Ophthalmic lubricating spray |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL126590A (en) * | 1996-05-07 | 2001-11-25 | Pfizer | Trihydrate salt of -5 (-2 (-4 (1 (2, 2-benzothiazole - 3yl) -1-piperazinyl) ethyl) - 6-chloro-1, 3-dihydro-2 (1H) - indole - 2On (= Ziprasidone) and pharmaceutical preparations containing it |
TW491847B (en) * | 1996-05-07 | 2002-06-21 | Pfizer | Mesylate dihydrate salts of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one |
EP0985414B1 (en) * | 1998-05-26 | 2003-08-27 | Pfizer Products Inc. | Medicament for the treatment of glaucoma and ischemic retinopathy |
JP2002541098A (ja) * | 1999-04-06 | 2002-12-03 | セプラコア インコーポレーテッド | ジプラシドン代謝産物を用いる神経弛緩薬性障害および関連障害を治療するための方法および組成物 |
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2001
- 2001-05-28 NZ NZ551012A patent/NZ551012A/en unknown
- 2001-05-28 KR KR1020027016364A patent/KR20030007824A/ko not_active Application Discontinuation
- 2001-05-28 DK DK04013380T patent/DK1468686T3/da active
- 2001-05-28 PL PL01365576A patent/PL365576A1/xx unknown
- 2001-05-28 DE DE60124791T patent/DE60124791T2/de not_active Expired - Fee Related
- 2001-05-28 JP JP2001587771A patent/JP2003534381A/ja not_active Withdrawn
- 2001-05-28 HU HU0301747A patent/HUP0301747A2/hu unknown
- 2001-05-28 WO PCT/IB2001/000933 patent/WO2001091756A2/en active IP Right Grant
- 2001-05-28 PT PT06116051T patent/PT1698338E/pt unknown
- 2001-05-28 MX MXPA02011862A patent/MXPA02011862A/es active IP Right Grant
- 2001-05-28 AT AT04013380T patent/ATE345818T1/de not_active IP Right Cessation
- 2001-05-28 EP EP06116051A patent/EP1698338B1/en not_active Expired - Lifetime
- 2001-05-28 SI SI200130681T patent/SI1468686T1/sl unknown
- 2001-05-28 UA UA2002119557A patent/UA79425C2/uk unknown
- 2001-05-28 CN CN01810620A patent/CN1431901A/zh active Pending
- 2001-05-28 YU YU90702A patent/YU90702A/sh unknown
- 2001-05-28 EE EEP200200670A patent/EE200200670A/xx unknown
- 2001-05-28 AU AU2001258690A patent/AU2001258690A1/en not_active Abandoned
- 2001-05-28 EA EA200201168A patent/EA007068B1/ru not_active IP Right Cessation
- 2001-05-28 PT PT04013380T patent/PT1468686E/pt unknown
- 2001-05-28 ES ES04013380T patent/ES2277170T3/es not_active Expired - Lifetime
- 2001-05-28 AT AT01932011T patent/ATE343387T1/de not_active IP Right Cessation
- 2001-05-28 EP EP01932011A patent/EP1286672B1/en not_active Expired - Lifetime
- 2001-05-28 CA CA002410618A patent/CA2410618A1/en not_active Abandoned
- 2001-05-28 IL IL15278201A patent/IL152782A0/xx active IP Right Grant
- 2001-05-28 GE GE4972A patent/GEP20053512B/en unknown
- 2001-05-28 CZ CZ20023860A patent/CZ20023860A3/cs unknown
- 2001-05-28 AT AT06116051T patent/ATE391507T1/de not_active IP Right Cessation
- 2001-05-28 SK SK1662-2002A patent/SK16622002A3/sk not_active Application Discontinuation
- 2001-05-28 DE DE60133596T patent/DE60133596D1/de not_active Expired - Lifetime
- 2001-05-28 OA OA1200200349A patent/OA12267A/en unknown
- 2001-05-28 EP EP04013380A patent/EP1468686B1/en not_active Expired - Lifetime
- 2001-05-28 DE DE60124093T patent/DE60124093D1/de not_active Expired - Lifetime
- 2001-05-28 BR BR0111271-6A patent/BR0111271A/pt not_active Application Discontinuation
- 2001-05-31 AP APAP/P/2001/002180A patent/AP1831A/en active
- 2001-05-31 AP AP2005003272A patent/AP1747A/xx active
- 2001-05-31 UY UY26742A patent/UY26742A1/es not_active Application Discontinuation
- 2001-05-31 PE PE2001000504A patent/PE20011329A1/es not_active Application Discontinuation
- 2001-05-31 HN HN2001000119A patent/HN2001000119A/es unknown
- 2001-05-31 DO DO2001000181A patent/DOP2001000181A/es unknown
- 2001-06-01 SV SV2001000473A patent/SV2002000473A/es not_active Application Discontinuation
- 2001-06-01 PA PA20018518301A patent/PA8518301A1/es unknown
- 2001-06-01 AR ARP010102641A patent/AR028937A1/es unknown
- 2001-06-04 US US09/873,973 patent/US20060287336A1/en not_active Abandoned
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2002
- 2002-11-11 IL IL152782A patent/IL152782A/en not_active IP Right Cessation
- 2002-11-12 BG BG107267A patent/BG107267A/bg unknown
- 2002-11-14 IS IS6619A patent/IS6619A/is unknown
- 2002-11-28 ZA ZA200209665A patent/ZA200209665B/en unknown
- 2002-11-29 MA MA26927A patent/MA26908A1/fr unknown
- 2002-11-29 NO NO20025760A patent/NO325077B1/no unknown
- 2002-11-29 EC EC2002004369A patent/ECSP024369A/es unknown
- 2002-12-02 HR HR20020953A patent/HRP20020953A2/hr not_active Application Discontinuation
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2007
- 2007-02-08 CY CY20071100161T patent/CY1105992T1/el unknown
- 2007-11-14 JP JP2007296039A patent/JP2008056700A/ja not_active Withdrawn
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