CY1105200T1 - Μεθοδος δια την παραγωγη διπepιδενης ii - Google Patents

Μεθοδος δια την παραγωγη διπepιδενης ii

Info

Publication number
CY1105200T1
CY1105200T1 CY20061101286T CY061101286T CY1105200T1 CY 1105200 T1 CY1105200 T1 CY 1105200T1 CY 20061101286 T CY20061101286 T CY 20061101286T CY 061101286 T CY061101286 T CY 061101286T CY 1105200 T1 CY1105200 T1 CY 1105200T1
Authority
CY
Cyprus
Prior art keywords
production
dipepidene
propanone
hept
exo
Prior art date
Application number
CY20061101286T
Other languages
English (en)
Inventor
Peter Klein
Marco Thyes
Markus Grosse
Klaus Martin Weber
Elmar Vilsmaier
Original Assignee
Laboratorio Farmaceutico S.I.T. Specialita´ Igienico Terapeutiche S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Farmaceutico S.I.T. Specialita´ Igienico Terapeutiche S.R.L. filed Critical Laboratorio Farmaceutico S.I.T. Specialita´ Igienico Terapeutiche S.R.L.
Publication of CY1105200T1 publication Critical patent/CY1105200T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Abstract

Η εφεύρεση αφορά μια μέθοδο δια την παραγωγή διπεριδένης δι' αντιδράσεως ενός έξω/ένδο μίγματος 1 - (δίκυκλο [2.2.1] επτ - 5 - εν - 2 - υλ) 3 - πιπεριδίνο - 1 - προπανόνης με μια ένωση φαίνυλο μαγνησίου, όπου η έξω/ένδο αναλογία της 1 - (δίκυκλο [2.2.1] επτ - 5 - εν - 2 - υλ) 3 -πιπεριδίνο - 1 - προπανόνης είναι τουλάχιστον 4.5 :1.
CY20061101286T 2001-05-18 2006-09-08 Μεθοδος δια την παραγωγη διπepιδενης ii CY1105200T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10124449A DE10124449A1 (de) 2001-05-18 2001-05-18 Verfahren zur Herstellung von Biperiden
PCT/EP2002/005500 WO2002094781A1 (de) 2001-05-18 2002-05-17 Verfahren zur herstellung von biperiden ii

Publications (1)

Publication Number Publication Date
CY1105200T1 true CY1105200T1 (el) 2010-03-03

Family

ID=7685401

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20061101286T CY1105200T1 (el) 2001-05-18 2006-09-08 Μεθοδος δια την παραγωγη διπepιδενης ii

Country Status (14)

Country Link
US (1) US6835839B2 (el)
EP (1) EP1389188B1 (el)
JP (1) JP4451600B2 (el)
KR (1) KR100896837B1 (el)
CN (1) CN1247543C (el)
AT (1) ATE331710T1 (el)
BR (1) BRPI0209852B8 (el)
CY (1) CY1105200T1 (el)
DE (2) DE10124449A1 (el)
DK (1) DK1389188T3 (el)
ES (1) ES2268090T3 (el)
IL (2) IL158933A0 (el)
PT (1) PT1389188E (el)
WO (1) WO2002094781A1 (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10124451A1 (de) * 2001-05-18 2002-11-21 Abbott Gmbh & Co Kg Verfahren zur Herstellung von Biperiden
JP4338979B2 (ja) * 2001-05-18 2009-10-07 アボット ゲーエムベーハー ウント カンパニー カーゲー ビペリデン（ｉ）の製造方法
DE10124453A1 (de) * 2001-05-18 2002-11-21 Abbott Gmbh & Co Kg Verfahren zur Herstellung von Biperiden
DE10124449A1 (de) 2001-05-18 2002-11-21 Abbott Gmbh & Co Kg Verfahren zur Herstellung von Biperiden
DE102005030745B4 (de) 2005-06-29 2008-05-29 Schleifring Und Apparatebau Gmbh HF-Spulen für Kernspintomographen
CN106187948B (zh) * 2016-08-02 2019-02-22 安徽省逸欣铭医药科技有限公司 盐酸比哌立登制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1005067B (de) * 1953-03-14 1957-03-28 Knoll Ag Verfahren zur Herstellung von bicyclisch substituierten Aminopropanolen
US2789110A (en) 1953-03-14 1957-04-16 Knoll Ag Amino alcohols substituted by bicycloalkyl residues and a process of making same
JPH11189729A (ja) 1997-12-26 1999-07-13 Chemiprokasei Kaisha Ltd 色素兼紫外線安定剤およびそれを含む高分子組成物
DE10124449A1 (de) 2001-05-18 2002-11-21 Abbott Gmbh & Co Kg Verfahren zur Herstellung von Biperiden

Also Published As

Publication number Publication date
KR100896837B1 (ko) 2009-05-12
BRPI0209852B1 (pt) 2016-08-02
IL158933A (en) 2009-12-24
JP4451600B2 (ja) 2010-04-14
IL158933A0 (en) 2004-05-12
EP1389188B1 (de) 2006-06-28
KR20040007580A (ko) 2004-01-24
JP2005515154A (ja) 2005-05-26
US20040152899A1 (en) 2004-08-05
CN1525958A (zh) 2004-09-01
US6835839B2 (en) 2004-12-28
DE50207388D1 (de) 2006-08-10
ES2268090T3 (es) 2007-03-16
BRPI0209852B8 (pt) 2021-05-25
DK1389188T3 (da) 2006-10-30
BR0209852A (pt) 2007-01-02
ATE331710T1 (de) 2006-07-15
WO2002094781A1 (de) 2002-11-28
PT1389188E (pt) 2006-11-30
CN1247543C (zh) 2006-03-29
EP1389188A1 (de) 2004-02-18
DE10124449A1 (de) 2002-11-21

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