HUP0303153A2 - N-metil-paroxetin és intermedierjei előállítására - Google Patents

N-metil-paroxetin és intermedierjei előállítására

Info

Publication number
HUP0303153A2
HUP0303153A2 HU0303153A HUP0303153A HUP0303153A2 HU P0303153 A2 HUP0303153 A2 HU P0303153A2 HU 0303153 A HU0303153 A HU 0303153A HU P0303153 A HUP0303153 A HU P0303153A HU P0303153 A2 HUP0303153 A2 HU P0303153A2
Authority
HU
Hungary
Prior art keywords
methylparoxetine
preparation
intermediate compounds
subject
cipma
Prior art date
Application number
HU0303153A
Other languages
English (en)
Inventor
Nina Finkelstein
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of HUP0303153A2 publication Critical patent/HUP0303153A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Abstract

A találmány tárgya eljárás N-metil-paroxetin, a paroxetinintermedierjének előállítására szezamol-butil-ammóniumsóreagáltatásával CIPMA-val. A találmány tárgya továbbá az N-metil-paroxetinhez hasonló egyéb vegyületek előállítása is. Ó
HU0303153A 2001-02-05 2002-02-04 N-metil-paroxetin és intermedierjei előállítására HUP0303153A2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26649801P 2001-02-05 2001-02-05
US27758701P 2001-03-21 2001-03-21
PCT/US2002/003223 WO2002062790A1 (en) 2001-02-05 2002-02-04 Preparation of n-methylparoxetine and related intermediate compounds

Publications (1)

Publication Number Publication Date
HUP0303153A2 true HUP0303153A2 (hu) 2004-03-01

Family

ID=26951885

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303153A HUP0303153A2 (hu) 2001-02-05 2002-02-04 N-metil-paroxetin és intermedierjei előállítására

Country Status (10)

Country Link
US (1) US6777554B2 (hu)
EP (1) EP1366041A4 (hu)
KR (1) KR20040014452A (hu)
CA (1) CA2437392A1 (hu)
CZ (1) CZ20032354A3 (hu)
HR (1) HRP20030690A2 (hu)
HU (1) HUP0303153A2 (hu)
IL (1) IL157243A0 (hu)
SK (1) SK10992003A3 (hu)
WO (1) WO2002062790A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040087795A1 (en) * 2000-07-17 2004-05-06 Borrett Gary Thomas Novel processes for the preparation of 4-phenylpiperidine derivatives
US20080029570A1 (en) * 2006-08-02 2008-02-07 Shelton Frederick E Pneumatically powered surgical cutting and fastening instrument with improved volume storage
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
US4585777A (en) 1984-02-07 1986-04-29 A/S Ferrosan (-)-Trans-4-(4-fluorophenyl)-3-(4-methoxyphenoxy)methylpiperidine for potentiating 5-HT
DE3680184D1 (de) 1985-08-10 1991-08-14 Beecham Group Plc Verfahren zur herstellung von arylpiperidincarbinol.
IE66332B1 (en) 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
GB8714707D0 (en) 1987-06-23 1987-07-29 Beecham Group Plc Chemical process
EP0351283A1 (fr) 1988-07-12 1990-01-17 Synthelabo Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique
FR2634207B1 (fr) 1988-07-12 1990-09-07 Synthelabo Derives de ((piperidinyl-4)methyl) benzazepines, leur preparation et leur application en therapeutique
FR2659323B1 (fr) 1990-03-07 1992-06-12 Synthelabo Derives de 4-(aminomethyl) piperidine, leur preparation et leur application en therapeutique.
US5258517A (en) 1992-08-06 1993-11-02 Sepracor, Inc. Method of preparing optically pure precursors of paroxetine
US6004990A (en) 1994-06-03 1999-12-21 Zebra Pharmaceuticals Meta substituted arylalkylamines and therapeutic and diagnostic uses therefor
GB9526645D0 (en) 1995-12-28 1996-02-28 Chiroscience Ltd Stereoselective synthesis
JP3882224B2 (ja) 1996-05-31 2007-02-14 旭硝子株式会社 パロキセチンの製造方法
EP1384711A1 (en) 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Optical resolution of a piperidine derivative
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
GB9710004D0 (en) 1997-05-17 1997-07-09 Knoll Ag Chemical process
US20040087795A1 (en) 2000-07-17 2004-05-06 Borrett Gary Thomas Novel processes for the preparation of 4-phenylpiperidine derivatives
IL159280A0 (en) * 2001-06-14 2004-06-01 Teva Pharma A process for preparing paroxetine hcl which limits formation of pink colored compounds
CN1336363A (zh) * 2001-07-25 2002-02-20 张元宾 乙酰磺胺酸钾的合成制备方法
IL161521A0 (en) 2001-10-22 2004-09-27 Synthon Bv N-formyl derivatives of paroxetine

Also Published As

Publication number Publication date
KR20040014452A (ko) 2004-02-14
CA2437392A1 (en) 2002-08-15
IL157243A0 (en) 2004-02-19
EP1366041A1 (en) 2003-12-03
WO2002062790A1 (en) 2002-08-15
EP1366041A4 (en) 2004-12-22
US6777554B2 (en) 2004-08-17
SK10992003A3 (sk) 2004-03-02
HRP20030690A2 (en) 2005-04-30
US20020151567A1 (en) 2002-10-17
CZ20032354A3 (cs) 2004-08-18

Similar Documents

Publication Publication Date Title
HUP0302345A2 (hu) Új triazolo-pirimidin-vegyületek, ezek intermedierjei és eljárás az előállításukra
NL300933I2 (nl) Letermovir
ECSP095220A (es) Derivados de n-fenil-2-pirimidin-amina
NO20062644L (no) DPP-IV inhibitorer
TW200510325A (en) 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof
TW200621739A (en) Asymmetric synthesis of substituted dihydrobenzofurans
EA200600621A1 (ru) Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств
NO20073678L (no) Nye fremgangsmater for fremstilling av benzofuran
PL371127A1 (en) 6-aminomorphinane derivatives, method for the production and use thereof
HUP0301076A2 (hu) Linezolid II kristályforma és előállítása
TW200728310A (en) Process for the preparation of ferri-succinylcasein
TW200635905A (en) Processes for producing 4-aminoquinazolines
IS8159A (is) Aðferð til að framleiða (4-hýdroxý-6-oxó-tetrahýdrópýran-2-ýl) asetonítríl og afleiður þess
TW200621703A (en) Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
CY1107101T1 (el) Μεθοδος συνθεσης παραγωγων της 1,3-διϋδρο-2h-3-βενζαζεπιν-2-ονης και εφαρμογη στη συνθεση της ιβαβραδινης και των αλατων προσθηκης με φαρμακευτικως αποδεκτο οξυ
RS8604A (en) Process for the production of beraprost and its salts
HUP0303844A2 (hu) Eljárás tioszemikarbazidok előállítására
EA200600563A1 (ru) Способ получения рензаприда и его промежуточных соединений
HUP0303153A2 (hu) N-metil-paroxetin és intermedierjei előállítására
BR0214445B1 (pt) processos para a produção de compostos.
BRPI0411652A (pt) processo para a preparação de derivados de espirobenzoazepina substituìdos não-peptìdicos
EA200600542A1 (ru) Способ для производства thip
HUP0400767A2 (hu) Javított eljárás tiszta ondansetron-hidroklorid-dihidrát előállítására
EA200300771A1 (ru) Новая соль бензоилгуанидина
MXPA03012073A (es) Amidoderivados heterociclicos.