CU20150174A7 - Método para generar una composición farmacéutica purificada de un complejo de radionúclido emisor alfa - Google Patents

Método para generar una composición farmacéutica purificada de un complejo de radionúclido emisor alfa

Info

Publication number
CU20150174A7
CU20150174A7 CUP2015000174A CU20150174A CU20150174A7 CU 20150174 A7 CU20150174 A7 CU 20150174A7 CU P2015000174 A CUP2015000174 A CU P2015000174A CU 20150174 A CU20150174 A CU 20150174A CU 20150174 A7 CU20150174 A7 CU 20150174A7
Authority
CU
Cuba
Prior art keywords
complex
generating
radionucclid
issuer
alfa
Prior art date
Application number
CUP2015000174A
Other languages
English (en)
Other versions
CU24535B1 (es
Inventor
Janne Olsen Frenvik
Olav B Ryan
Alan Cuthbertson
Original Assignee
Bayer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer As filed Critical Bayer As
Publication of CU20150174A7 publication Critical patent/CU20150174A7/es
Publication of CU24535B1 publication Critical patent/CU24535B1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1075Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an enzyme
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1051Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Dispersion Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

Un método para generar una solución purificada de por lo menos un complejo de radionúclido emisor alfa. El método comprende poner en contacto una solución del complejo de radionúclido emisor alfa y por lo menos un núclido hijo que tiene por lo menos un ligante selectivo para los núclidos hijos y subsiguientemente separar la solución del ligante selectivo. También, un método para preparar por lo menos un radionúclido hijo de una solución que comprende por lo menos un complejo de radionúclido emisor alfa. El método comprende poner en contacto la solución que tiene por lo menos un ligante selectivo para los núclidos hijos.
CU2015000174A 2013-06-05 2014-06-05 Método para generar una solución purificada de un isótopo de torio emisor alfa CU24535B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1310028.4A GB201310028D0 (en) 2013-06-05 2013-06-05 Pharmaceutical preparation
PCT/EP2014/061743 WO2014195423A1 (en) 2013-06-05 2014-06-05 Pharmaceutical preparation

Publications (2)

Publication Number Publication Date
CU20150174A7 true CU20150174A7 (es) 2016-06-29
CU24535B1 CU24535B1 (es) 2021-07-02

Family

ID=48805787

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2015000174A CU24535B1 (es) 2013-06-05 2014-06-05 Método para generar una solución purificada de un isótopo de torio emisor alfa

Country Status (36)

Country Link
US (2) US20160114063A1 (es)
EP (1) EP3003401B1 (es)
JP (1) JP6580559B2 (es)
KR (1) KR102321763B1 (es)
CN (1) CN105592863B (es)
AP (1) AP2015008894A0 (es)
AU (1) AU2014276885B2 (es)
BR (1) BR112015030298A2 (es)
CA (1) CA2914278C (es)
CL (1) CL2015003554A1 (es)
CR (1) CR20150642A (es)
CU (1) CU24535B1 (es)
DK (1) DK3003401T3 (es)
DO (1) DOP2015000294A (es)
EA (1) EA201501174A1 (es)
ES (1) ES2782624T3 (es)
GB (1) GB201310028D0 (es)
HR (1) HRP20200456T1 (es)
IL (1) IL242704B (es)
LT (1) LT3003401T (es)
MA (1) MA38650B1 (es)
MX (1) MX366028B (es)
MY (1) MY180717A (es)
NI (1) NI201500173A (es)
PE (1) PE20160215A1 (es)
PH (1) PH12015502715A1 (es)
PL (1) PL3003401T3 (es)
PT (1) PT3003401T (es)
RS (1) RS60091B1 (es)
SA (1) SA515370233B1 (es)
SG (1) SG11201509856RA (es)
SI (1) SI3003401T1 (es)
TN (1) TN2015000527A1 (es)
UA (1) UA120352C2 (es)
WO (1) WO2014195423A1 (es)
ZA (1) ZA201600027B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201600158D0 (en) * 2016-01-05 2016-02-17 Bayer As Purification method
GB201600161D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope purification method
MX2022006638A (es) 2019-12-05 2022-07-19 Sciencons AS Producción de 212pb altamente purificados.
US20240108766A1 (en) 2021-01-22 2024-04-04 Bayer Aktiengesellschaft Lrrc15 antibodies and conjugates thereof
NO347755B1 (en) * 2021-10-21 2024-03-18 Blue Wave Therapeutics Gmbh Peptide-coupled alginate gels comprising radionuclides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749042A (en) * 1997-01-28 1998-05-05 Battelle Memorial Institute Bismuth generator method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
US8481694B2 (en) * 2009-04-29 2013-07-09 Bio-Rad Laboratories, Inc. Purification of immunoconjugates
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201105298D0 (en) * 2011-03-29 2011-05-11 Algeta Asa Pharmaceutical preparation

Also Published As

Publication number Publication date
SA515370233B1 (ar) 2019-05-30
US20160114063A1 (en) 2016-04-28
JP6580559B2 (ja) 2019-09-25
US20220023449A1 (en) 2022-01-27
KR20160030893A (ko) 2016-03-21
HRP20200456T1 (hr) 2020-06-26
DOP2015000294A (es) 2016-03-15
KR102321763B1 (ko) 2021-11-05
PL3003401T3 (pl) 2020-07-27
MA38650A1 (fr) 2018-03-30
AU2014276885A1 (en) 2015-12-17
PH12015502715B1 (en) 2016-03-28
MA38650B1 (fr) 2019-05-31
CU24535B1 (es) 2021-07-02
CR20150642A (es) 2016-07-22
CN105592863A (zh) 2016-05-18
WO2014195423A1 (en) 2014-12-11
PE20160215A1 (es) 2016-05-22
ZA201600027B (en) 2018-07-25
EA201501174A1 (ru) 2016-10-31
SG11201509856RA (en) 2015-12-30
CA2914278A1 (en) 2014-12-11
NI201500173A (es) 2016-01-06
JP2016521700A (ja) 2016-07-25
AU2014276885B2 (en) 2018-12-06
UA120352C2 (uk) 2019-11-25
BR112015030298A2 (pt) 2017-07-25
LT3003401T (lt) 2020-06-25
PT3003401T (pt) 2020-04-09
DK3003401T3 (da) 2020-04-06
SI3003401T1 (sl) 2020-06-30
CL2015003554A1 (es) 2016-07-15
RS60091B1 (sr) 2020-05-29
CA2914278C (en) 2022-11-01
EP3003401B1 (en) 2020-01-15
NZ714737A (en) 2021-02-26
EP3003401A1 (en) 2016-04-13
MX366028B (es) 2019-06-21
PH12015502715A1 (en) 2016-03-28
ES2782624T3 (es) 2020-09-15
GB201310028D0 (en) 2013-07-17
MY180717A (en) 2020-12-07
TN2015000527A1 (en) 2017-04-06
IL242704B (en) 2020-06-30
MX2015016726A (es) 2016-06-28
AP2015008894A0 (en) 2015-12-31
CN105592863B (zh) 2020-03-10

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