EA201501174A1 - Фармацевтический препарат для применения в эндорадионуклидной терапии - Google Patents

Фармацевтический препарат для применения в эндорадионуклидной терапии

Info

Publication number
EA201501174A1
EA201501174A1 EA201501174A EA201501174A EA201501174A1 EA 201501174 A1 EA201501174 A1 EA 201501174A1 EA 201501174 A EA201501174 A EA 201501174A EA 201501174 A EA201501174 A EA 201501174A EA 201501174 A1 EA201501174 A1 EA 201501174A1
Authority
EA
Eurasian Patent Office
Prior art keywords
solution
application
pharmaceutical preparation
alpha
endoradionuclide therapy
Prior art date
Application number
EA201501174A
Other languages
English (en)
Inventor
Янне Олсен Френвик
Улав Б. Рюан
Алан Катбертсон
Original Assignee
Байер Ас
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байер Ас filed Critical Байер Ас
Publication of EA201501174A1 publication Critical patent/EA201501174A1/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1075Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an enzyme
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1051Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Saccharide Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

Настоящее изобретение обеспечивает способ образования очищенного раствора как минимум одного излучающего альфа-частицы радионуклидного комплекса. Способ включает контактирование раствора излучающего альфа-частицы радионуклидного комплекса и как минимум одного дочернего нуклида с как минимум одним селективным связующим веществом для дочернего нуклида и последующее отделение раствора от селективного связующего вещества. Изобретение также обеспечивает способ удаления как минимум одного дочернего радионуклида из раствора, включающего как минимум один излучающий альфа-частицы радионуклидный комплекс. Способ включает контактирование раствора с как минимум одним селективным связующим веществом для дочернего нуклида.
EA201501174A 2013-06-05 2014-06-05 Фармацевтический препарат для применения в эндорадионуклидной терапии EA201501174A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1310028.4A GB201310028D0 (en) 2013-06-05 2013-06-05 Pharmaceutical preparation
PCT/EP2014/061743 WO2014195423A1 (en) 2013-06-05 2014-06-05 Pharmaceutical preparation

Publications (1)

Publication Number Publication Date
EA201501174A1 true EA201501174A1 (ru) 2016-10-31

Family

ID=48805787

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201501174A EA201501174A1 (ru) 2013-06-05 2014-06-05 Фармацевтический препарат для применения в эндорадионуклидной терапии

Country Status (36)

Country Link
US (2) US20160114063A1 (ru)
EP (1) EP3003401B1 (ru)
JP (1) JP6580559B2 (ru)
KR (1) KR102321763B1 (ru)
CN (1) CN105592863B (ru)
AP (1) AP2015008894A0 (ru)
AU (1) AU2014276885B2 (ru)
BR (1) BR112015030298A2 (ru)
CA (1) CA2914278C (ru)
CL (1) CL2015003554A1 (ru)
CR (1) CR20150642A (ru)
CU (1) CU24535B1 (ru)
DK (1) DK3003401T3 (ru)
DO (1) DOP2015000294A (ru)
EA (1) EA201501174A1 (ru)
ES (1) ES2782624T3 (ru)
GB (1) GB201310028D0 (ru)
HR (1) HRP20200456T1 (ru)
IL (1) IL242704B (ru)
LT (1) LT3003401T (ru)
MA (1) MA38650B1 (ru)
MX (1) MX366028B (ru)
MY (1) MY180717A (ru)
NI (1) NI201500173A (ru)
PE (1) PE20160215A1 (ru)
PH (1) PH12015502715B1 (ru)
PL (1) PL3003401T3 (ru)
PT (1) PT3003401T (ru)
RS (1) RS60091B1 (ru)
SA (1) SA515370233B1 (ru)
SG (1) SG11201509856RA (ru)
SI (1) SI3003401T1 (ru)
TN (1) TN2015000527A1 (ru)
UA (1) UA120352C2 (ru)
WO (1) WO2014195423A1 (ru)
ZA (1) ZA201600027B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201600158D0 (en) * 2016-01-05 2016-02-17 Bayer As Purification method
GB201600161D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope purification method
MX2023008628A (es) 2021-01-22 2023-09-22 Bayer Ag Anticuerpos lrrc15 y conjugados de los mismos.
NO347755B1 (en) * 2021-10-21 2024-03-18 Blue Wave Therapeutics Gmbh Peptide-coupled alginate gels comprising radionuclides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749042A (en) * 1997-01-28 1998-05-05 Battelle Memorial Institute Bismuth generator method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
JP5863640B2 (ja) * 2009-04-29 2016-02-16 バイオ−ラッド ラボラトリーズ インコーポレーティッド 免疫複合体の精製
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201105298D0 (en) * 2011-03-29 2011-05-11 Algeta Asa Pharmaceutical preparation

Also Published As

Publication number Publication date
US20220023449A1 (en) 2022-01-27
CA2914278A1 (en) 2014-12-11
PT3003401T (pt) 2020-04-09
NZ714737A (en) 2021-02-26
KR102321763B1 (ko) 2021-11-05
CR20150642A (es) 2016-07-22
SG11201509856RA (en) 2015-12-30
PH12015502715A1 (en) 2016-03-28
ZA201600027B (en) 2018-07-25
PH12015502715B1 (en) 2016-03-28
ES2782624T3 (es) 2020-09-15
GB201310028D0 (en) 2013-07-17
JP2016521700A (ja) 2016-07-25
HRP20200456T1 (hr) 2020-06-26
AU2014276885A1 (en) 2015-12-17
MX2015016726A (es) 2016-06-28
MA38650B1 (fr) 2019-05-31
EP3003401A1 (en) 2016-04-13
CA2914278C (en) 2022-11-01
IL242704B (en) 2020-06-30
PE20160215A1 (es) 2016-05-22
SA515370233B1 (ar) 2019-05-30
TN2015000527A1 (en) 2017-04-06
CN105592863B (zh) 2020-03-10
RS60091B1 (sr) 2020-05-29
CN105592863A (zh) 2016-05-18
DOP2015000294A (es) 2016-03-15
SI3003401T1 (sl) 2020-06-30
MX366028B (es) 2019-06-21
NI201500173A (es) 2016-01-06
DK3003401T3 (da) 2020-04-06
UA120352C2 (uk) 2019-11-25
MY180717A (en) 2020-12-07
AP2015008894A0 (en) 2015-12-31
BR112015030298A2 (pt) 2017-07-25
EP3003401B1 (en) 2020-01-15
KR20160030893A (ko) 2016-03-21
PL3003401T3 (pl) 2020-07-27
LT3003401T (lt) 2020-06-25
CU24535B1 (es) 2021-07-02
JP6580559B2 (ja) 2019-09-25
US20160114063A1 (en) 2016-04-28
CU20150174A7 (es) 2016-06-29
CL2015003554A1 (es) 2016-07-15
MA38650A1 (fr) 2018-03-30
WO2014195423A1 (en) 2014-12-11
AU2014276885B2 (en) 2018-12-06

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