CS273186B2 - Method of spiroimidazolidinedione production - Google Patents
Method of spiroimidazolidinedione production Download PDFInfo
- Publication number
- CS273186B2 CS273186B2 CS591188A CS591188A CS273186B2 CS 273186 B2 CS273186 B2 CS 273186B2 CS 591188 A CS591188 A CS 591188A CS 591188 A CS591188 A CS 591188A CS 273186 B2 CS273186 B2 CS 273186B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- product
- mol
- chloro
- pyrano
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1987/002196 WO1989001775A1 (en) | 1987-09-04 | 1987-09-04 | Azolidinedione derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS591188A2 CS591188A2 (en) | 1990-06-13 |
| CS273186B2 true CS273186B2 (en) | 1991-03-12 |
Family
ID=22202540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS591188A CS273186B2 (en) | 1987-09-04 | 1988-09-02 | Method of spiroimidazolidinedione production |
Country Status (21)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5068333A (en) * | 1990-03-07 | 1991-11-26 | Pfizer Inc. | 6-chloro-3,4-dihydro-pyrano [2,3-b]pyridines having the R configuration |
| DE10210195B4 (de) | 2002-03-07 | 2005-12-15 | Schwarz Pharma Ag | Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz |
| KR101308227B1 (ko) * | 2005-04-21 | 2013-09-13 | 이시하라 산교 가부시끼가이샤 | 니코틴산 유도체 또는 그의 염의 제조 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
| US4176185A (en) * | 1979-01-22 | 1979-11-27 | Pfizer Inc. | Spiro-quinolylhydantoins |
| US4226875A (en) * | 1979-04-02 | 1980-10-07 | Pfizer Inc. | Novel spiro-oxazolidinediones |
| FR2455046A1 (fr) * | 1979-04-25 | 1980-11-21 | Science Union & Cie | Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament |
| US4235911A (en) * | 1979-06-13 | 1980-11-25 | Pfizer Inc. | Hydantoin derivatives |
| US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
| EP0065392B1 (en) * | 1981-05-13 | 1985-02-13 | Imperial Chemical Industries Plc | Pharmaceutical compositions containing spiro succinimide derivatives |
-
1987
- 1987-09-04 WO PCT/US1987/002196 patent/WO1989001775A1/en active Application Filing
- 1987-09-04 MX MX1289688A patent/MX12896A/es unknown
- 1987-09-04 HU HU875809A patent/HU204832B/hu not_active IP Right Cessation
-
1988
- 1988-08-29 MY MYPI88000968A patent/MY103765A/en unknown
- 1988-08-29 IL IL87590A patent/IL87590A/xx unknown
- 1988-08-30 EP EP88307985A patent/EP0306251A3/en not_active Withdrawn
- 1988-09-01 JP JP63219621A patent/JPS6471882A/ja active Granted
- 1988-09-01 ZA ZA886507A patent/ZA886507B/xx unknown
- 1988-09-01 EG EG465/88A patent/EG18591A/xx active
- 1988-09-02 AU AU21841/88A patent/AU595467B2/en not_active Ceased
- 1988-09-02 CS CS591188A patent/CS273186B2/cs not_active IP Right Cessation
- 1988-09-02 DD DD88319458A patent/DD273381A5/de not_active IP Right Cessation
- 1988-09-02 PL PL1988274504A patent/PL156798B1/pl unknown
- 1988-09-02 PT PT88407A patent/PT88407B/pt not_active IP Right Cessation
- 1988-09-02 YU YU167788A patent/YU46863B/sh unknown
- 1988-09-02 PH PH37490A patent/PH24957A/en unknown
- 1988-09-02 DK DK488688A patent/DK488688A/da not_active Application Discontinuation
- 1988-09-03 CN CN88106484A patent/CN1022325C/zh not_active Expired - Fee Related
- 1988-09-03 KR KR1019880011369A patent/KR900008841B1/ko not_active IP Right Cessation
-
1990
- 1990-03-02 NO NO90901016A patent/NO901016L/no unknown
- 1990-03-02 FI FI901087A patent/FI901087A0/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| YU167788A (en) | 1990-06-30 |
| ZA886507B (en) | 1990-04-25 |
| CN1031702A (zh) | 1989-03-15 |
| CN1022325C (zh) | 1993-10-06 |
| IL87590A (en) | 1992-07-15 |
| DK488688D0 (da) | 1988-09-02 |
| JPS6471882A (en) | 1989-03-16 |
| FI901087A0 (fi) | 1990-03-02 |
| NO901016D0 (no) | 1990-03-02 |
| HU204832B (en) | 1992-02-28 |
| EG18591A (en) | 1993-06-30 |
| HUT56106A (en) | 1991-07-29 |
| NO901016L (no) | 1990-05-02 |
| CS591188A2 (en) | 1990-06-13 |
| WO1989001775A1 (en) | 1989-03-09 |
| KR890005112A (ko) | 1989-05-11 |
| JPH0583554B2 (US06312121-20011106-C00033.png) | 1993-11-26 |
| AU595467B2 (en) | 1990-03-29 |
| PL274504A1 (en) | 1989-05-02 |
| DK488688A (da) | 1989-04-07 |
| YU46863B (sh) | 1994-06-24 |
| AU2184188A (en) | 1989-03-09 |
| PT88407B (pt) | 1992-10-30 |
| EP0306251A2 (en) | 1989-03-08 |
| KR900008841B1 (ko) | 1990-11-30 |
| EP0306251A3 (en) | 1990-08-01 |
| PT88407A (pt) | 1989-07-31 |
| PL156798B1 (pl) | 1992-04-30 |
| MX12896A (es) | 1993-06-01 |
| IL87590A0 (en) | 1989-01-31 |
| PH24957A (en) | 1990-12-26 |
| MY103765A (en) | 1993-09-30 |
| DD273381A5 (de) | 1989-11-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CS199690B2 (cs) | Způsob výroby spiro-hydantoinových derivátů | |
| EP0034063B1 (en) | Hydantoin amines and pharmaceutical compositions thereof | |
| US4980357A (en) | Azolidinedione derivatives | |
| FI93013B (fi) | Menetelmä terapeuttisesti käyttökelpoisten pyridopyridatsinonijohdannaisten valmistamiseksi | |
| US4307108A (en) | Method for lowering sorbitol levels using spiro-imides | |
| EP0021704B1 (en) | Spiro-hydantoin derivatives, process for their preparation and pharmaceutical compositions thereof | |
| JPH0825877B2 (ja) | 眼科治療用組成物 | |
| CS273186B2 (en) | Method of spiroimidazolidinedione production | |
| EP0269355B1 (en) | Imidazolidinedione derivatives | |
| PL147397B1 (en) | Method of obtaining novel derivatives of spiro imidazolidine | |
| EP0014079B1 (en) | Spiro-quinolylhydantoins, process for their preparation and pharmaceutical compositions thereof | |
| FI78699C (fi) | Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara spiro-imidazolidin-2,2',5-trionderivat. | |
| EP0028485B1 (en) | Spiro-imidazolones for alleviating diabetes-associated conditions, processes for preparing them, and pharmaceutical compositions containing them | |
| EP0017477B1 (en) | Spiro-quinolone hydantoins, pharmaceutical compositions containing them, and processes for their preparation | |
| CA1226866A (en) | Hydantoin derivatives | |
| US4442114A (en) | Imide derivatives | |
| US5418232A (en) | Diazabicycloalkene derivatives | |
| RU1838313C (ru) | Способ получени спиросоединени азолона или его N-оксидного производного или его основной соли с фармакологически применимым катионом | |
| NZ226030A (en) | Spiro-azolone derivatives; pharmaceutical compositions | |
| KR860001870B1 (ko) | 이미다졸리딘디온 유도체의 제조방법 | |
| FI81575C (fi) | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara spiro-imidazolidin-4,3'-azaindolin-2,2',5 -trionderivat. | |
| JPH08277266A (ja) | スピロ三環式芳香族スクシンイミド誘導体、並びにヒト及び動物の糖尿病合併症治療剤 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| IF00 | In force as of 2000-06-30 in czech republic | ||
| MM4A | Patent lapsed due to non-payment of fee |
Effective date: 20050902 |