CS261894B2 - Method of 7-oxo-prostacycline's analogues salts production - Google Patents

Method of 7-oxo-prostacycline's analogues salts production Download PDF

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Publication number
CS261894B2
CS261894B2 CS863877A CS387786A CS261894B2 CS 261894 B2 CS261894 B2 CS 261894B2 CS 863877 A CS863877 A CS 863877A CS 387786 A CS387786 A CS 387786A CS 261894 B2 CS261894 B2 CS 261894B2
Authority
CS
Czechoslovakia
Prior art keywords
group
oxo
formula
ephedrine
carbon atoms
Prior art date
Application number
CS863877A
Other languages
Czech (cs)
English (en)
Inventor
Gabor Dr Kovacs
Geza Dr Galambos
Istvan Dr Tomoskozi
Karoly Kanai
Peter Dr Gyory
Peter Dr Kormoczy
Istvan Dr Stadler
Laszlo Dr Szekeres
Gyula Dr Papp
Eva Dr Udvary
Pal Dr Hadhazy
Jeno Dr Marton
Gyorgy Dorman
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS261894B2 publication Critical patent/CS261894B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
CS863877A 1985-05-29 1986-05-27 Method of 7-oxo-prostacycline's analogues salts production CS261894B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852050A HU197733B (en) 1985-05-29 1985-05-29 Process for producing ephedrin-salts of 7-oxo-prosta-cyclin derivatives

Publications (1)

Publication Number Publication Date
CS261894B2 true CS261894B2 (en) 1989-02-10

Family

ID=10957509

Family Applications (1)

Application Number Title Priority Date Filing Date
CS863877A CS261894B2 (en) 1985-05-29 1986-05-27 Method of 7-oxo-prostacycline's analogues salts production

Country Status (23)

Country Link
US (1) US4735965A (ja)
EP (1) EP0205969B1 (ja)
JP (1) JPS61277650A (ja)
KR (1) KR860009031A (ja)
CN (1) CN1010587B (ja)
AT (1) ATE71093T1 (ja)
AU (1) AU588761B2 (ja)
CS (1) CS261894B2 (ja)
DD (1) DD244977A5 (ja)
DE (1) DE3683192D1 (ja)
DK (1) DK249686A (ja)
ES (1) ES8706624A1 (ja)
FI (1) FI82690C (ja)
GR (1) GR861390B (ja)
HU (1) HU197733B (ja)
IL (1) IL78849A (ja)
NO (1) NO171677C (ja)
NZ (1) NZ216339A (ja)
PL (1) PL148718B1 (ja)
PT (1) PT82657B (ja)
SU (2) SU1454250A3 (ja)
YU (1) YU46169B (ja)
ZA (1) ZA863801B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729153D0 (en) * 1987-12-14 1988-01-27 Efamol Ltd Fatty acid compositions
HU227157B1 (en) * 2001-07-30 2010-09-28 Chinoin Gyogyszer Es Vegyeszet Production of beraprost ester by selective oxidation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU502731B2 (en) * 1975-09-17 1979-08-09 The Upjohn Company Prostaglandin analogues
IT1088036B (it) * 1977-11-25 1985-06-04 Erba Carlo Spa 15-epi-prostaciclina e prostaciclina analoghi
US4258199A (en) * 1978-03-13 1981-03-24 Research Corporation Method for preparing cyclic ethers and thioethers including oxygen isomers and sulfur analogs of prostacyclin
US4330553A (en) * 1979-11-12 1982-05-18 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same
HU182012B (en) * 1979-11-12 1983-12-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6-substituted-7-oxo-pgi down 1 derivatives
DE3035454A1 (de) * 1980-09-18 1982-04-22 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7-oxoprostacyclinderivate und verfahren zu ihrer herstellung
HU191264B (en) * 1984-01-13 1987-01-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for production of derivatives of 7-oxo-prostacyclin with selective biological effect

Also Published As

Publication number Publication date
HU197733B (en) 1989-05-29
EP0205969A3 (en) 1989-04-19
FI82690C (fi) 1991-04-10
CN1010587B (zh) 1990-11-28
EP0205969A2 (de) 1986-12-30
ZA863801B (en) 1987-01-28
GR861390B (en) 1986-09-17
PT82657A (en) 1986-06-01
EP0205969B1 (de) 1992-01-02
CN86103741A (zh) 1987-02-18
SU1454250A3 (ru) 1989-01-23
YU90986A (en) 1988-02-29
ES555454A0 (es) 1987-07-01
IL78849A (en) 1990-01-18
NO862112L (no) 1986-12-01
FI862159A0 (fi) 1986-05-22
FI82690B (fi) 1990-12-31
PT82657B (pt) 1988-03-03
JPS61277650A (ja) 1986-12-08
IL78849A0 (en) 1986-09-30
NO171677C (no) 1993-04-21
ES8706624A1 (es) 1987-07-01
DE3683192D1 (de) 1992-02-13
AU588761B2 (en) 1989-09-21
DD244977A5 (de) 1987-04-22
DK249686D0 (da) 1986-05-28
HUT40635A (en) 1987-01-28
ATE71093T1 (de) 1992-01-15
NZ216339A (en) 1989-08-29
DK249686A (da) 1986-11-30
KR860009031A (ko) 1986-12-19
AU5800186A (en) 1986-12-04
US4735965A (en) 1988-04-05
NO171677B (no) 1993-01-11
PL148718B1 (en) 1989-11-30
FI862159A (fi) 1986-11-30
YU46169B (sh) 1993-05-28
SU1447823A1 (ru) 1988-12-30

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