CS255887B2 - Process for preparing derivatives of 5,6-dihydro-4h-cyclopent/b/-6-thiophene - Google Patents

Process for preparing derivatives of 5,6-dihydro-4h-cyclopent/b/-6-thiophene Download PDF

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Publication number
CS255887B2
CS255887B2 CS855107A CS510785A CS255887B2 CS 255887 B2 CS255887 B2 CS 255887B2 CS 855107 A CS855107 A CS 855107A CS 510785 A CS510785 A CS 510785A CS 255887 B2 CS255887 B2 CS 255887B2
Authority
CS
Czechoslovakia
Prior art keywords
dihydro
methyl
group
mol
acid
Prior art date
Application number
CS855107A
Other languages
Czech (cs)
English (en)
Other versions
CS510785A2 (en
Inventor
Gerard Ferrand
Jacques Barbanton
Jean-Claude Depin
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lipha filed Critical Lipha
Publication of CS510785A2 publication Critical patent/CS510785A2/cs
Publication of CS255887B2 publication Critical patent/CS255887B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CS855107A 1984-07-09 1985-07-08 Process for preparing derivatives of 5,6-dihydro-4h-cyclopent/b/-6-thiophene CS255887B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8410861A FR2567125B1 (fr) 1984-07-09 1984-07-09 Acides dihydro-5,6-4h-cyclopenta (b) thiophenecarboxylique-6, procedes de preparation et medicaments les contenant

Publications (2)

Publication Number Publication Date
CS510785A2 CS510785A2 (en) 1987-07-16
CS255887B2 true CS255887B2 (en) 1988-03-15

Family

ID=9305925

Family Applications (1)

Application Number Title Priority Date Filing Date
CS855107A CS255887B2 (en) 1984-07-09 1985-07-08 Process for preparing derivatives of 5,6-dihydro-4h-cyclopent/b/-6-thiophene

Country Status (26)

Country Link
US (1) US4649153A (da)
EP (1) EP0172041B1 (da)
JP (1) JPH072733B2 (da)
AR (1) AR242381A1 (da)
AT (1) ATE36329T1 (da)
AU (1) AU573147B2 (da)
CA (1) CA1249834A (da)
CS (1) CS255887B2 (da)
DD (1) DD235454A5 (da)
DE (1) DE3564268D1 (da)
DK (1) DK161321C (da)
ES (1) ES8604550A1 (da)
FR (1) FR2567125B1 (da)
GR (1) GR851609B (da)
HU (1) HU202519B (da)
IE (1) IE58362B1 (da)
IL (1) IL75527A (da)
IN (1) IN166471B (da)
MA (1) MA20481A1 (da)
MX (1) MX162258A (da)
NO (1) NO171499C (da)
NZ (1) NZ212619A (da)
OA (1) OA08076A (da)
SU (1) SU1402261A3 (da)
YU (1) YU113885A (da)
ZA (1) ZA854519B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692460A (en) * 1986-12-24 1987-09-08 Mcneilab, Inc. Cyclopenta[b]thiophenes having anti-inflammatory activity similar to steroids
IL103106A (en) * 1991-09-25 1998-06-15 Sanofi Elf Sites of tynocyclopentanone oximes, their preparation and pharmaceutical preparations containing them
JP2011525537A (ja) * 2008-06-24 2011-09-22 ブリストル−マイヤーズ スクイブ カンパニー グルココルチコイド受容体、AP−1、および/またはNF−κB活性のシクロペンタチオフェン調節剤およびその使用
RU2661151C1 (ru) * 2017-12-14 2018-07-12 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Селективные ингибиторы глицеральдегид-3-фосфатдегидрогеназы микобактерий

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2167334A1 (en) * 1972-01-13 1973-08-24 Roussel Uclaf 4-aroyl-5-alkylthiophene-2-acetic acids - with analgesic and antiinflammatory activity
SE7411096L (da) * 1973-09-11 1975-03-12 Sandoz Ag

Also Published As

Publication number Publication date
ES544961A0 (es) 1986-02-01
IL75527A0 (en) 1985-10-31
FR2567125B1 (fr) 1986-12-05
DK310685A (da) 1986-01-10
GR851609B (da) 1985-11-26
SU1402261A3 (ru) 1988-06-07
NO852741L (no) 1986-01-10
HUT38331A (en) 1986-05-28
DK310685D0 (da) 1985-07-08
EP0172041B1 (fr) 1988-08-10
FR2567125A1 (fr) 1986-01-10
ZA854519B (en) 1986-02-26
NO171499B (no) 1992-12-14
IE58362B1 (en) 1993-09-08
AR242381A1 (es) 1993-03-31
NZ212619A (en) 1988-02-12
OA08076A (fr) 1987-03-31
DE3564268D1 (en) 1988-09-15
ES8604550A1 (es) 1986-02-01
DK161321C (da) 1992-01-06
AU573147B2 (en) 1988-05-26
AU4362585A (en) 1986-01-16
JPS6140280A (ja) 1986-02-26
YU113885A (en) 1987-10-31
IL75527A (en) 1988-11-30
EP0172041A1 (fr) 1986-02-19
DK161321B (da) 1991-06-24
MA20481A1 (fr) 1986-04-01
IN166471B (da) 1990-05-19
US4649153A (en) 1987-03-10
CA1249834A (fr) 1989-02-07
IE851486L (en) 1986-01-09
ATE36329T1 (de) 1988-08-15
MX162258A (es) 1991-04-18
HU202519B (en) 1991-03-28
JPH072733B2 (ja) 1995-01-18
CS510785A2 (en) 1987-07-16
NO171499C (no) 1993-03-24
DD235454A5 (de) 1986-05-07

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