CS233740B2 - Processing of 3-benzazepin compositions - Google Patents
Processing of 3-benzazepin compositions Download PDFInfo
- Publication number
- CS233740B2 CS233740B2 CS828075A CS807582A CS233740B2 CS 233740 B2 CS233740 B2 CS 233740B2 CS 828075 A CS828075 A CS 828075A CS 807582 A CS807582 A CS 807582A CS 233740 B2 CS233740 B2 CS 233740B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- benzazepine
- chloro
- compounds
- solution
- pressure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32524981A | 1981-11-27 | 1981-11-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
CS233740B2 true CS233740B2 (en) | 1985-03-14 |
Family
ID=23267072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS828075A CS233740B2 (en) | 1981-11-27 | 1982-11-12 | Processing of 3-benzazepin compositions |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPS5892616A (ko) |
KR (1) | KR840002358A (ko) |
CS (1) | CS233740B2 (ko) |
HU (1) | HU190648B (ko) |
SU (1) | SU1238732A3 (ko) |
ZA (1) | ZA827887B (ko) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4541954A (en) * | 1984-09-05 | 1985-09-17 | Smithkline Beckman Corporation | Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
PL2332921T3 (pl) | 2003-06-17 | 2016-08-31 | Arena Pharm Inc | Chlorowodorek 8-chloro-1-metylo-2,3,4,5-tetrahydro-1H-3-benzazepiny |
EP2332920A3 (en) | 2003-06-17 | 2011-12-21 | Arena Pharmaceuticals, Inc. | Processes for preparing 3-benzazepines |
NZ555482A (en) | 2004-12-23 | 2011-01-28 | Arena Pharm Inc | Compositions comprising a 5HT2C receptor modulator and 2-methylamphetamine and methods of use |
EP2471779A1 (en) | 2006-04-03 | 2012-07-04 | Arena Pharmaceuticals, Inc. | Process for the resolution of a mixture of (R)- and (S)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
ES2522587T3 (es) | 2006-12-05 | 2014-11-17 | Arena Pharmaceuticals, Inc. | Procesos para preparar (R)-8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzacepina e intermedios de la misma |
WO2009111004A1 (en) | 2008-03-04 | 2009-09-11 | Arena Pharmaceuticals, Inc. | Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine |
US8952197B2 (en) | 2009-06-18 | 2015-02-10 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-HT2C receptor agonists |
KR20130112848A (ko) | 2010-06-02 | 2013-10-14 | 아레나 파마슈티칼스, 인크. | 5-ht2c 수용체 아고니스트의 제조 방법 |
CN103347523A (zh) | 2010-09-01 | 2013-10-09 | 艾尼纳制药公司 | 向具有肾损伤的个体给药氯卡色林 |
WO2012030957A2 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
CA2808909A1 (en) | 2010-09-01 | 2012-03-08 | Arena Pharmaceuticals, Inc. | Salts of lorcaserin with optically active acids |
BR112015007779A2 (pt) | 2012-10-09 | 2017-07-04 | Arena Pharm Inc | célula de fluxo de permeabilidade e sistema de condutância hidráulica |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4265890A (en) * | 1978-07-07 | 1981-05-05 | Smithkline Corporation | 6-Phenyl thio- and 6-cyclohexyl thio-2,3,4,5-tetrahydro-1H-3-benzazepines |
-
1982
- 1982-10-28 ZA ZA827887A patent/ZA827887B/xx unknown
- 1982-11-12 CS CS828075A patent/CS233740B2/cs unknown
- 1982-11-16 JP JP57201817A patent/JPS5892616A/ja active Pending
- 1982-11-24 KR KR1019820005307A patent/KR840002358A/ko unknown
- 1982-11-25 SU SU823513948A patent/SU1238732A3/ru active
- 1982-11-26 HU HU823814A patent/HU190648B/hu unknown
Also Published As
Publication number | Publication date |
---|---|
HU190648B (en) | 1986-09-29 |
SU1238732A3 (ru) | 1986-06-15 |
JPS5892616A (ja) | 1983-06-02 |
ZA827887B (en) | 1983-11-30 |
KR840002358A (ko) | 1984-06-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0080779B1 (en) | 3-benzazepines as alpha-2 antagonists | |
US3681459A (en) | Guanidine compounds and use of same | |
CA1081229A (en) | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl) piperazine hydrochloride dihydrate | |
CS233740B2 (en) | Processing of 3-benzazepin compositions | |
US20060014786A1 (en) | Opthalmic pharmaceutical compositions and methods for treating ocular inflammation | |
US6268359B1 (en) | Preventives or remedies for vision disorders | |
US7084157B2 (en) | Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation | |
JPS63264421A (ja) | 高脂質血症治療剤 | |
US4496558A (en) | Pharmaceutical compositions and methods for producing alpha antagonism | |
Wand et al. | Thymoxamine hydrochloride: an alpha-adrenergic blocker | |
US7105528B2 (en) | Benzo [g] quinoline derivatives for treating glaucoma and myopia | |
WO1997024333A1 (fr) | Composes de prevention/traitement s'appliquant aux complications de diabetes | |
GB2291592A (en) | Pharmaceutical compositions comprising a bicycloheptane derivative | |
JPH0532635A (ja) | ヒスタミン誘導体の治療への応用と、新規なヒスタミン誘導体と、この誘導体の医薬としての使用 | |
EP1480970B1 (en) | Quinoline derivatives | |
CA1214165A (en) | Pharmaceutical compositions and method of producing alpha.sub.2 antagonism | |
EP0108170A1 (en) | 3-Benzazepines as alpha-2 antagonists | |
EP1884236A1 (en) | Angiogenesis inhibitor containing amine derivative as active ingredient | |
EP0223811A1 (en) | Use of nicorandil or pinacidil for the treatment of peripheral vascular disease | |
WO2004075895A1 (ja) | 眼圧低下剤 | |
US5504087A (en) | 1-phenoxy-2-propanol derivatives useful in treating hypertension and glaucoma | |
EP1051973B1 (en) | Optic papillary circulation improving agents | |
CA2743782A1 (en) | Therapeutic agent for chorioretinal degenerative disease containing pyridine-3-carbaldehyde o-(piperidin-1-yl-propyl)-oxime derivative as active ingredient | |
EP0115331B1 (en) | Medicament for cerebral apoplexy | |
KR20030002304A (ko) | 3-페닐-3,7-디아자비시클로[3.3.1]노난 화합물들과 이들의제조방법 및 이러한 화합물들을 포함하는 약제들 |