CS226907B1 - Alkylamides of carboxyalkanoylpeptides - Google Patents

Alkylamides of carboxyalkanoylpeptides Download PDF

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Publication number
CS226907B1
CS226907B1 CS815977A CS597781A CS226907B1 CS 226907 B1 CS226907 B1 CS 226907B1 CS 815977 A CS815977 A CS 815977A CS 597781 A CS597781 A CS 597781A CS 226907 B1 CS226907 B1 CS 226907B1
Authority
CS
Czechoslovakia
Prior art keywords
alanine
alanyl
ethylamide
formula
ala
Prior art date
Application number
CS815977A
Other languages
Czech (cs)
English (en)
Inventor
Evzen Ing Csc Kasafirek
Premysl Doc Mudr Drsc Fric
Jan Ing Mudr Slaby
Alena Roubalova
Original Assignee
Kasafirek Evzen
Premysl Doc Mudr Drsc Fric
Jan Ing Mudr Slaby
Alena Roubalova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kasafirek Evzen, Premysl Doc Mudr Drsc Fric, Jan Ing Mudr Slaby, Alena Roubalova filed Critical Kasafirek Evzen
Priority to CS815977A priority Critical patent/CS226907B1/cs
Priority to IT22506/82A priority patent/IT1156108B/it
Priority to FR8213346A priority patent/FR2510990B1/fr
Priority to JP57134793A priority patent/JPS5849351A/ja
Priority to CA000408760A priority patent/CA1238902A/en
Priority to GB08222574A priority patent/GB2104082B/en
Priority to HU822541A priority patent/HU193029B/hu
Priority to CH4752/82A priority patent/CH653038A5/de
Priority to DE19823229632 priority patent/DE3229632A1/de
Priority to BE0/208777A priority patent/BE894065A/fr
Priority to US06/406,168 priority patent/US4554100A/en
Publication of CS226907B1 publication Critical patent/CS226907B1/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CS815977A 1981-08-07 1981-08-07 Alkylamides of carboxyalkanoylpeptides CS226907B1 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CS815977A CS226907B1 (en) 1981-08-07 1981-08-07 Alkylamides of carboxyalkanoylpeptides
IT22506/82A IT1156108B (it) 1981-08-07 1982-07-21 Alchilamidi di carbossialcanoil peptidi
FR8213346A FR2510990B1 (fr) 1981-08-07 1982-07-30 Alcoylamides de carboxyalcanoylpeptides
JP57134793A JPS5849351A (ja) 1981-08-07 1982-08-03 カルボキシアルカノイルペプチドのアルキルアミド
CA000408760A CA1238902A (en) 1981-08-07 1982-08-05 Alkylamides of carboxyalkanoyl peptides
GB08222574A GB2104082B (en) 1981-08-07 1982-08-05 Alkylamides of carboxyalkanoyl peptides
HU822541A HU193029B (en) 1981-08-07 1982-08-06 Process for preparing carboxy-alkanoyl-peptide-alkylamide derivatives
CH4752/82A CH653038A5 (de) 1981-08-07 1982-08-06 Carboxyalkanoylpeptid-alkylamide.
DE19823229632 DE3229632A1 (de) 1981-08-07 1982-08-09 Carboxyalkanoylpeptid-alkylamide, ihre herstellung und pharmazeutische mittel
BE0/208777A BE894065A (fr) 1981-08-07 1982-08-09 Alkylamides de carboxy-alcanoyl-peptides
US06/406,168 US4554100A (en) 1981-08-07 1982-08-09 Alkylamides of carboxyalkanoyl peptides and method for preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS815977A CS226907B1 (en) 1981-08-07 1981-08-07 Alkylamides of carboxyalkanoylpeptides

Publications (1)

Publication Number Publication Date
CS226907B1 true CS226907B1 (en) 1984-04-16

Family

ID=5405786

Family Applications (1)

Application Number Title Priority Date Filing Date
CS815977A CS226907B1 (en) 1981-08-07 1981-08-07 Alkylamides of carboxyalkanoylpeptides

Country Status (11)

Country Link
US (1) US4554100A (ja)
JP (1) JPS5849351A (ja)
BE (1) BE894065A (ja)
CA (1) CA1238902A (ja)
CH (1) CH653038A5 (ja)
CS (1) CS226907B1 (ja)
DE (1) DE3229632A1 (ja)
FR (1) FR2510990B1 (ja)
GB (1) GB2104082B (ja)
HU (1) HU193029B (ja)
IT (1) IT1156108B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS231228B1 (en) * 1982-10-01 1984-10-15 Evzen Kasafirek Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.
NZ214543A (en) * 1984-12-14 1990-03-27 Australian Commercial Research Amino acid and peptide derivatives that inhibit human leucocytic elastase enzyme (hle)
FR2733995B1 (fr) * 1995-05-09 1997-07-25 Inst Nat Sante Rech Med Inhibiteurs de l'inactivation de neuropeptides endogenes notamment la cholecystokinine, leurs procedes de preparation leur utilisation comme medicaments et procede de criblage de medicaments
AU2016281685B2 (en) 2015-06-24 2021-08-12 Nitto Denko Corporation Ionizable compounds and compositions and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4064236A (en) * 1975-12-23 1977-12-20 Merck & Co., Inc. Peptide carbazates and pharmaceutical composition
US4029772A (en) * 1975-12-23 1977-06-14 Merck & Co., Inc. Peptide carbazates
CH626872A5 (ja) * 1976-06-21 1981-12-15 Hoffmann La Roche
CH627735A5 (de) * 1976-06-25 1982-01-29 Hoffmann La Roche Verfahren zur herstellung von dipeptidderivaten.
FR2381023A1 (fr) * 1977-02-18 1978-09-15 Delalande Sa Nouveaux oligopeptides trifluoromethyles derives de la l-alanine, leur procede de preparation et leur application en therapeutique
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
BE894065A (fr) 1982-12-01
CH653038A5 (de) 1985-12-13
CA1238902A (en) 1988-07-05
JPS5849351A (ja) 1983-03-23
US4554100A (en) 1985-11-19
GB2104082A (en) 1983-03-02
DE3229632C2 (ja) 1988-06-23
GB2104082B (en) 1984-09-12
FR2510990B1 (fr) 1986-05-09
JPH0349918B2 (ja) 1991-07-31
IT8222506A0 (it) 1982-07-21
HU193029B (en) 1987-08-28
IT1156108B (it) 1987-01-28
FR2510990A1 (fr) 1983-02-11
IT8222506A1 (it) 1984-01-21
DE3229632A1 (de) 1983-02-24

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