CS219851B2 - Method of making the crystallic hydrochloride or hydrobromide of the pivaloyloxymethylester 7beta-/2-/2-amino-4-thiazzolyl/-2-methoxyiminoacetamido/-3-cefem-4-carboxyle acid - Google Patents

Method of making the crystallic hydrochloride or hydrobromide of the pivaloyloxymethylester 7beta-/2-/2-amino-4-thiazzolyl/-2-methoxyiminoacetamido/-3-cefem-4-carboxyle acid Download PDF

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Publication number
CS219851B2
CS219851B2 CS81685A CS68581A CS219851B2 CS 219851 B2 CS219851 B2 CS 219851B2 CS 81685 A CS81685 A CS 81685A CS 68581 A CS68581 A CS 68581A CS 219851 B2 CS219851 B2 CS 219851B2
Authority
CS
Czechoslovakia
Prior art keywords
amino
methoxyiminoacetamido
thiazolyl
hydrochloride
hydrobromide
Prior art date
Application number
CS81685A
Other languages
Czech (cs)
English (en)
Inventor
Riccardo Scartazzini
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CS219851B2 publication Critical patent/CS219851B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Seasonings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Sorption Type Refrigeration Machines (AREA)
  • Magnetic Heads (AREA)
  • Fats And Perfumes (AREA)
  • Liquid Crystal Substances (AREA)
CS81685A 1980-02-01 1981-01-30 Method of making the crystallic hydrochloride or hydrobromide of the pivaloyloxymethylester 7beta-/2-/2-amino-4-thiazzolyl/-2-methoxyiminoacetamido/-3-cefem-4-carboxyle acid CS219851B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH83680 1980-02-01

Publications (1)

Publication Number Publication Date
CS219851B2 true CS219851B2 (en) 1983-03-25

Family

ID=4196332

Family Applications (1)

Application Number Title Priority Date Filing Date
CS81685A CS219851B2 (en) 1980-02-01 1981-01-30 Method of making the crystallic hydrochloride or hydrobromide of the pivaloyloxymethylester 7beta-/2-/2-amino-4-thiazzolyl/-2-methoxyiminoacetamido/-3-cefem-4-carboxyle acid

Country Status (26)

Country Link
US (1) US4411897A (fr)
EP (1) EP0033518B1 (fr)
JP (1) JPS56122382A (fr)
KR (1) KR840000502B1 (fr)
AT (1) ATE3550T1 (fr)
AU (1) AU6677981A (fr)
CA (1) CA1146540A (fr)
CS (1) CS219851B2 (fr)
DD (1) DD157462A5 (fr)
DE (1) DE3160328D1 (fr)
DK (1) DK32081A (fr)
ES (1) ES8204439A1 (fr)
FI (1) FI66874B (fr)
GR (1) GR78221B (fr)
IE (1) IE50888B1 (fr)
IL (1) IL62017A (fr)
MC (1) MC1367A1 (fr)
MT (1) MTP882B (fr)
NO (1) NO810338L (fr)
NZ (1) NZ196159A (fr)
OA (1) OA06732A (fr)
PL (1) PL125899B1 (fr)
PT (1) PT72421A (fr)
SU (1) SU1036250A1 (fr)
ZA (1) ZA81631B (fr)
ZW (1) ZW2281A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2111043B (en) * 1980-12-12 1985-02-06 Ciba Geigy Ag Novel cephalosporin esters
US4594417A (en) * 1981-10-30 1986-06-10 Eli Lilly Company Crystalline antibiotic salt
US4400503A (en) * 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
JPS60190783A (ja) * 1983-12-21 1985-09-28 Sumitomo Seiyaku Kk セフエム系化合物
US4683227A (en) * 1985-07-09 1987-07-28 Eli Lilly And Company Antibiotic derivatives of 7β-[2-(thiazol-4-yl)acetamide]-3-chloro-3-cephem-4-carboxylic acids and compositions and method of use thereof
JPH02101081A (ja) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd セファロスポリン誘導体結晶性二塩酸塩及びその製造法
EP0638573A1 (fr) * 1993-08-10 1995-02-15 Lucky Ltd. Hydrates crystallins d'une céphalosporine et procédé pour leur préparation
US20040067192A1 (en) * 2002-10-07 2004-04-08 The Procter & Gamble Company Conversion of sodium bromide to anhydrous hydrobromic acid and sodium bisulfate
EP1606293B1 (fr) * 2003-03-27 2009-08-19 Basilea Pharmaceutica AG Cephalosporine sous forme cristalline

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
GB2025933B (en) 1978-06-13 1982-10-27 Fujisawa Pharmaceutical Co Cephem and cepham compounds
MA18686A1 (fr) * 1978-07-07 1980-10-01 Ciba Geigy Ag Composes aminothiazoliques
JPS5543011A (en) * 1978-09-20 1980-03-26 Shionogi & Co Ltd 7-halothiazolylalkoxyiminoacetamido-3-cephem compound
JPS5579393A (en) * 1978-12-11 1980-06-14 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal

Also Published As

Publication number Publication date
KR840000502B1 (ko) 1984-04-16
DD157462A5 (de) 1982-11-10
MC1367A1 (fr) 1981-10-23
IL62017A (en) 1984-06-29
PL125899B1 (en) 1983-06-30
SU1036250A1 (ru) 1983-08-15
ZW2281A1 (en) 1981-09-02
ES498989A0 (es) 1982-05-01
GR78221B (fr) 1984-09-26
CA1146540A (fr) 1983-05-17
OA06732A (fr) 1982-06-30
AU6677981A (en) 1981-08-06
ES8204439A1 (es) 1982-05-01
ZA81631B (en) 1982-02-24
FI66874B (fi) 1984-08-31
DK32081A (da) 1981-08-02
IL62017A0 (en) 1981-02-27
DE3160328D1 (en) 1983-07-07
JPS56122382A (en) 1981-09-25
MTP882B (en) 1984-06-05
ATE3550T1 (de) 1983-06-15
EP0033518B1 (fr) 1983-05-25
EP0033518A1 (fr) 1981-08-12
KR830005235A (ko) 1983-08-03
NO810338L (no) 1981-08-03
IE810176L (en) 1981-08-01
NZ196159A (en) 1983-09-30
IE50888B1 (en) 1986-08-06
PT72421A (de) 1981-02-01
PL229457A1 (fr) 1981-10-02
FI810270L (fi) 1981-08-02
US4411897A (en) 1983-10-25

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