CS202056B2 - Process for preparing derivatives for preparing 7-aminocephalosporanic acid and ester thereof - Google Patents

Process for preparing derivatives for preparing 7-aminocephalosporanic acid and ester thereof Download PDF

Info

Publication number
CS202056B2
CS202056B2 CS755997A CS599775A CS202056B2 CS 202056 B2 CS202056 B2 CS 202056B2 CS 755997 A CS755997 A CS 755997A CS 599775 A CS599775 A CS 599775A CS 202056 B2 CS202056 B2 CS 202056B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
solution
formula
compound
tert
Prior art date
Application number
CS755997A
Other languages
Czech (cs)
English (en)
Inventor
William J Gottstein
Murray A Kaplan
Alphonse P Granatek
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CS202056B2 publication Critical patent/CS202056B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00Derivatives of isocyanic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CS755997A 1974-09-03 1975-09-03 Process for preparing derivatives for preparing 7-aminocephalosporanic acid and ester thereof CS202056B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50299174A 1974-09-03 1974-09-03

Publications (1)

Publication Number Publication Date
CS202056B2 true CS202056B2 (en) 1980-12-31

Family

ID=24000311

Family Applications (3)

Application Number Title Priority Date Filing Date
CS755997A CS202056B2 (en) 1974-09-03 1975-09-03 Process for preparing derivatives for preparing 7-aminocephalosporanic acid and ester thereof
CS773751A CS202058B2 (en) 1974-09-03 1977-06-07 Process for preparing derivatives of 7-aminocephalosporanic acid
CS773750A CS202057B2 (en) 1974-09-03 1977-06-07 Process for preparing derivative of 7-aminocephalosporanic acid

Family Applications After (2)

Application Number Title Priority Date Filing Date
CS773751A CS202058B2 (en) 1974-09-03 1977-06-07 Process for preparing derivatives of 7-aminocephalosporanic acid
CS773750A CS202057B2 (en) 1974-09-03 1977-06-07 Process for preparing derivative of 7-aminocephalosporanic acid

Country Status (14)

Country Link
JP (2) JPS60222489A (ja)
AT (3) AT349140B (ja)
AU (1) AU503240B2 (ja)
BE (1) BE832725A (ja)
BG (1) BG27753A3 (ja)
CH (1) CH623330A5 (ja)
CS (3) CS202056B2 (ja)
CY (1) CY1120A (ja)
GB (1) GB1525626A (ja)
HK (1) HK45081A (ja)
KE (1) KE3157A (ja)
MY (1) MY8200111A (ja)
SU (2) SU691094A3 (ja)
ZA (1) ZA755543B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4093723A (en) 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
US4082912A (en) 1976-06-30 1978-04-04 Bristol-Myers Company Certain 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylmethyl)-3-cephem-4-carboxylic acids their salts and easily hydrolyzed esters
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
US4117125A (en) 1977-06-24 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-[2-(carboxymethylamino]ethyl) tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
DK225179A (da) 1978-06-22 1979-12-23 Chugai Pharmaceutical Co Ltd Fremgangsmaade til fremstilling af cephalosporinderivater
JPH01300075A (ja) * 1988-05-25 1989-12-04 Tokyo Seimitsu Hatsujo Kk 流動体注入装置

Also Published As

Publication number Publication date
AT349140B (de) 1979-03-26
JPS6348870B2 (ja) 1988-09-30
AT349638B (de) 1979-04-10
MY8200111A (en) 1982-12-31
ATA676475A (de) 1978-08-15
KE3157A (en) 1981-09-18
JPS6135200B2 (ja) 1986-08-12
AU8446975A (en) 1977-03-10
JPS60222470A (ja) 1985-11-07
CS202058B2 (en) 1980-12-31
ATA723377A (de) 1978-07-15
BG27753A3 (en) 1979-12-12
ZA755543B (en) 1976-07-28
CS202057B2 (en) 1980-12-31
AU503240B2 (en) 1979-08-30
SU685157A3 (ru) 1979-09-05
AT348520B (de) 1979-02-26
ATA294178A (de) 1978-09-15
CH623330A5 (en) 1981-05-29
SU691094A3 (ru) 1979-10-05
JPS60222489A (ja) 1985-11-07
CY1120A (en) 1981-12-04
HK45081A (en) 1981-09-11
BE832725A (fr) 1976-02-25
GB1525626A (en) 1978-09-20

Similar Documents

Publication Publication Date Title
DK144763B (da) Analogifremgangsmaade til fremstilling af cephalosporinderivater
JPS6150955B2 (ja)
CH622262A5 (ja)
JPS6150957B2 (ja)
CA1135255A (en) Cephalosporin esters
EP0236231B1 (en) Novel cephem compounds
CS202056B2 (en) Process for preparing derivatives for preparing 7-aminocephalosporanic acid and ester thereof
GB1573004A (en) Cephalosporin compounds
HU193760B (en) Process for producing beta-lactame antibiotics and pharmaceutical and growth-controlling compositions containing them
CH622523A5 (ja)
US4220644A (en) 7-Acylamino-3-(substituted tetrazolyl thiomethyl) cephalosporins
JPS5917117B2 (ja) 抗菌剤の製法
US4104469A (en) 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US4576938A (en) Cephalosporin compound and process for preparing the same
RU2201933C2 (ru) Антибактериальные замещенные 7-ациламино-3-(метилгидразоно)метилцефалоспорины, способ их получения, фармацевтические композиции на их основе, промежуточные соединения и способ лечения заболеваний, вызванных микроорганизмами
HU200179B (en) Process for producing 7-square brackets open/meta-substituted/-phenylglycine-amido square brackets closed-1-carba-1-dethiacefems
US3720664A (en) Alpha-ureidocyclohexadienylalkylene-penicillins
JPS63165381A (ja) [3s(z)]−2−[[[1−(2−アミノ−4−チアゾリル)−2−[[2,2−ジメチル−4−オキソ−1−(スルホオキシ)−3−アゼチジニル]アミノ]−2−オキソエチリデン]アミノ]オキシ]酢酸の結晶塩
JPS59199693A (ja) インドリルグリシルセフアロスポリン誘導体
US4150224A (en) 7[[(1-Pyrrollyl)7 acetyl]amino]cephalosporin derivatives
JPS6337106B2 (ja)
US4180658A (en) 7[-2-Alkoxyamino(acetamido)]cephalosporin derivatives
US4046904A (en) Novel penicillin, and its preparation and use
GB1604740A (en) 7-isothiazolylthioacetamido-7-methoxycephalosporanic acid derivatives
US3780088A (en) Alpha-ureidocyclohexadienylalkylene carboxylic acids