GB1525626A - Tetrazolethiomethyl cephalosporin compounds - Google Patents
Tetrazolethiomethyl cephalosporin compoundsInfo
- Publication number
- GB1525626A GB1525626A GB36079/75A GB3607975A GB1525626A GB 1525626 A GB1525626 A GB 1525626A GB 36079/75 A GB36079/75 A GB 36079/75A GB 3607975 A GB3607975 A GB 3607975A GB 1525626 A GB1525626 A GB 1525626A
- Authority
- GB
- United Kingdom
- Prior art keywords
- tetrazolethiomethyl
- cephalosporin compounds
- formula
- reacting
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C265/00—Derivatives of isocyanic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Valuable antibiotics are obtained by reacting a compound of the formula <IMAGE> in which R<1> is acyl, or a salt or a readily hydrolysable ester thereof with 5-mercapto-1-tetrazoleacetic acid. The latter can be prepared by reacting sodium azide with an isocyanate of the formula ROOCCH2NCS and hydrolysing the resulting thiol ester.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50299174A | 1974-09-03 | 1974-09-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1525626A true GB1525626A (en) | 1978-09-20 |
Family
ID=24000311
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB36079/75A Expired GB1525626A (en) | 1974-09-03 | 1975-09-02 | Tetrazolethiomethyl cephalosporin compounds |
Country Status (14)
| Country | Link |
|---|---|
| JP (2) | JPS60222489A (en) |
| AT (3) | AT349140B (en) |
| AU (1) | AU503240B2 (en) |
| BE (1) | BE832725A (en) |
| BG (1) | BG27753A3 (en) |
| CH (1) | CH623330A5 (en) |
| CS (3) | CS202056B2 (en) |
| CY (1) | CY1120A (en) |
| GB (1) | GB1525626A (en) |
| HK (1) | HK45081A (en) |
| KE (1) | KE3157A (en) |
| MY (1) | MY8200111A (en) |
| SU (2) | SU691094A3 (en) |
| ZA (1) | ZA755543B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4298605A (en) | 1978-06-22 | 1981-11-03 | Chugai Seiyaku Kabushiki Kaisha | Cephalosporin derivatives |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4093723A (en) | 1976-05-19 | 1978-06-06 | Smithkline Corporation | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins |
| US4082912A (en) | 1976-06-30 | 1978-04-04 | Bristol-Myers Company | Certain 7-acylamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylmethyl)-3-cephem-4-carboxylic acids their salts and easily hydrolyzed esters |
| US4066762A (en) * | 1976-07-12 | 1978-01-03 | Smithkline Corporation | Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid |
| US4278670A (en) * | 1976-07-12 | 1981-07-14 | Smithkline Corporation | 7-Alpha-oxyiminoacylcephalosporins |
| US4117125A (en) | 1977-06-24 | 1978-09-26 | Smithkline Corporation | 7-Acylamino-3-[1-[2-(carboxymethylamino]ethyl) tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids |
| JPH01300075A (en) * | 1988-05-25 | 1989-12-04 | Tokyo Seimitsu Hatsujo Kk | Fluid pouring device |
-
1975
- 1975-08-25 BE BE159447A patent/BE832725A/en not_active IP Right Cessation
- 1975-08-29 ZA ZA00755543A patent/ZA755543B/en unknown
- 1975-09-01 BG BG036219A patent/BG27753A3/en active Active
- 1975-09-02 GB GB36079/75A patent/GB1525626A/en not_active Expired
- 1975-09-02 AU AU84469/75A patent/AU503240B2/en not_active Expired
- 1975-09-02 CH CH1134575A patent/CH623330A5/en not_active IP Right Cessation
- 1975-09-02 CY CY1120A patent/CY1120A/en unknown
- 1975-09-02 AT AT676475A patent/AT349140B/en not_active IP Right Cessation
- 1975-09-03 CS CS755997A patent/CS202056B2/en unknown
- 1975-09-03 SU SU752170664A patent/SU691094A3/en active
-
1976
- 1976-08-10 SU SU762388313A patent/SU685157A3/en active
-
1977
- 1977-06-07 CS CS773750A patent/CS202057B2/en unknown
- 1977-06-07 CS CS773751A patent/CS202058B2/en unknown
- 1977-10-10 AT AT723377A patent/AT348520B/en not_active IP Right Cessation
-
1978
- 1978-04-24 AT AT294178A patent/AT349638B/en not_active IP Right Cessation
-
1981
- 1981-08-25 KE KE3157A patent/KE3157A/en unknown
- 1981-09-03 HK HK450/81A patent/HK45081A/en unknown
-
1982
- 1982-12-30 MY MY111/82A patent/MY8200111A/en unknown
-
1985
- 1985-03-11 JP JP60046699A patent/JPS60222489A/en active Granted
- 1985-03-11 JP JP60046700A patent/JPS60222470A/en active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4298605A (en) | 1978-06-22 | 1981-11-03 | Chugai Seiyaku Kabushiki Kaisha | Cephalosporin derivatives |
| US4301161A (en) | 1978-06-22 | 1981-11-17 | Chugai Seiyaku Kabushiki Kaisha | Cephalosporin derivatives |
| US4328224A (en) | 1978-06-22 | 1982-05-04 | Chugai Seiyaku Kabushiki Kaisha | Cephalosporin derivatives |
| US4341776A (en) | 1978-06-22 | 1982-07-27 | Chugai Seiyaku Kabushiki Kaisha | Cephalosporin derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| CS202058B2 (en) | 1980-12-31 |
| CS202056B2 (en) | 1980-12-31 |
| HK45081A (en) | 1981-09-11 |
| SU691094A3 (en) | 1979-10-05 |
| JPS60222470A (en) | 1985-11-07 |
| ZA755543B (en) | 1976-07-28 |
| SU685157A3 (en) | 1979-09-05 |
| BE832725A (en) | 1976-02-25 |
| JPS6135200B2 (en) | 1986-08-12 |
| AU8446975A (en) | 1977-03-10 |
| CH623330A5 (en) | 1981-05-29 |
| AU503240B2 (en) | 1979-08-30 |
| AT349638B (en) | 1979-04-10 |
| JPS6348870B2 (en) | 1988-09-30 |
| MY8200111A (en) | 1982-12-31 |
| ATA676475A (en) | 1978-08-15 |
| ATA294178A (en) | 1978-09-15 |
| JPS60222489A (en) | 1985-11-07 |
| AT348520B (en) | 1979-02-26 |
| CY1120A (en) | 1981-12-04 |
| BG27753A3 (en) | 1979-12-12 |
| AT349140B (en) | 1979-03-26 |
| CS202057B2 (en) | 1980-12-31 |
| ATA723377A (en) | 1978-07-15 |
| KE3157A (en) | 1981-09-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| 48S | Specification amended (sect. 8/1949) | ||
| SP | Amendment (slips) printed | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19950901 |