CS201010B2 - Process for preparing derivatives of bis/nitrosoureido/-polyoles - Google Patents

Process for preparing derivatives of bis/nitrosoureido/-polyoles Download PDF

Info

Publication number
CS201010B2
CS201010B2 CS784690A CS469078A CS201010B2 CS 201010 B2 CS201010 B2 CS 201010B2 CS 784690 A CS784690 A CS 784690A CS 469078 A CS469078 A CS 469078A CS 201010 B2 CS201010 B2 CS 201010B2
Authority
CS
Czechoslovakia
Prior art keywords
bis
chloroethyl
water
carbon atoms
mol
Prior art date
Application number
CS784690A
Other languages
Czech (cs)
English (en)
Inventor
Tibor Horvath
Endre Csanyi
Sandor Eckhardt
Emilia Kiraly
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of CS201010B2 publication Critical patent/CS201010B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/66—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
    • C07C275/68—N-nitroso ureas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyurethanes Or Polyureas (AREA)
CS784690A 1977-12-29 1978-07-13 Process for preparing derivatives of bis/nitrosoureido/-polyoles CS201010B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77GO1386A HU176101B (en) 1977-12-29 1977-12-29 Process for producing bis-bracket-nitrozo-ureido-bracket closed-polyol derivatives

Publications (1)

Publication Number Publication Date
CS201010B2 true CS201010B2 (en) 1980-10-31

Family

ID=10996842

Family Applications (1)

Application Number Title Priority Date Filing Date
CS784690A CS201010B2 (en) 1977-12-29 1978-07-13 Process for preparing derivatives of bis/nitrosoureido/-polyoles

Country Status (28)

Country Link
US (1) US4237273A (it)
JP (1) JPS5495517A (it)
AT (1) AT360045B (it)
AU (1) AU523845B2 (it)
BE (1) BE868988A (it)
BG (1) BG30016A3 (it)
CA (1) CA1108182A (it)
CH (1) CH639363A5 (it)
CS (1) CS201010B2 (it)
DD (1) DD137224A5 (it)
DE (1) DE2831094A1 (it)
DK (1) DK155047C (it)
ES (1) ES471778A1 (it)
FI (1) FI69058C (it)
FR (1) FR2415096A1 (it)
GB (1) GB2011382B (it)
GR (1) GR64891B (it)
HU (1) HU176101B (it)
IL (1) IL55138A (it)
IT (1) IT1097647B (it)
NL (1) NL7807587A (it)
NO (1) NO149960C (it)
PL (1) PL112198B1 (it)
PT (1) PT68301A (it)
RO (1) RO77027A (it)
SE (1) SE446529B (it)
YU (1) YU41314B (it)
ZA (1) ZA783980B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459231A1 (fr) 1979-06-19 1981-01-09 Anvar Nouveaux derives de la cystamine utiles comme medicaments
JPS5775993A (en) * 1980-10-30 1982-05-12 Tetsuo Suami Novel nitrosourea derivative and its preparation
EP0428849A3 (en) * 1989-09-28 1991-07-31 Hoechst Aktiengesellschaft Retroviral protease inhibitors
WO1992000948A1 (en) * 1990-07-06 1992-01-23 Smithkline Beecham Corporation Inhibitors of retroviral proteases
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518270A (de) * 1969-03-07 1972-01-31 Hoffmann La Roche Verfahren zur Herstellung von Nitrosoharnstoffverbindungen
JPS5135382B2 (it) * 1972-08-04 1976-10-01
JPS50128266A (it) * 1974-03-26 1975-10-09
JPS5126876A (en) * 1974-08-08 1976-03-05 Suami T Shinkina nitorosonyosojudotaino seizohoho
US4066750A (en) * 1976-08-02 1978-01-03 Astra Chemical Products Ab Lactosyl substituted ureides in ruminant feedstuff
JPS5331664A (en) * 1976-09-02 1978-03-25 Suami T Production of novel nitroso urea derivatives
JPS5395917A (en) * 1977-02-03 1978-08-22 Tokyo Tanabe Co Process for preparing nitrosourea derivative of glucopyranose
US4148921A (en) * 1977-07-13 1979-04-10 Suami T Antitumor agents

Also Published As

Publication number Publication date
GB2011382A (en) 1979-07-11
CA1108182A (en) 1981-09-01
FR2415096A1 (fr) 1979-08-17
SE7807804L (sv) 1979-06-30
RO77027A (ro) 1981-11-04
FI69058B (fi) 1985-08-30
FR2415096B1 (it) 1982-12-10
IT7825682A0 (it) 1978-07-14
PL208436A1 (pl) 1979-07-02
SE446529B (sv) 1986-09-22
NO782447L (no) 1979-05-02
PL112198B1 (en) 1980-09-30
IL55138A0 (en) 1978-09-29
AU3802778A (en) 1980-01-17
DK155047B (da) 1989-01-30
DK155047C (da) 1989-06-26
BE868988A (fr) 1979-01-15
NL7807587A (nl) 1979-07-03
AT360045B (de) 1980-12-10
HU176101B (en) 1980-12-28
DK317878A (da) 1979-06-30
ATA500178A (de) 1980-05-15
GR64891B (en) 1980-06-06
IT1097647B (it) 1985-08-31
PT68301A (de) 1978-08-01
FI69058C (fi) 1985-12-10
CH639363A5 (de) 1983-11-15
DD137224A5 (de) 1979-08-22
JPS6250461B2 (it) 1987-10-24
IL55138A (en) 1982-05-31
YU169978A (en) 1982-10-31
NO149960C (no) 1984-07-25
US4237273A (en) 1980-12-02
AU523845B2 (en) 1982-08-19
BG30016A3 (en) 1981-03-16
DE2831094A1 (de) 1979-07-12
YU41314B (en) 1987-02-28
DE2831094C2 (it) 1988-12-15
ZA783980B (en) 1979-07-25
GB2011382B (en) 1982-08-18
JPS5495517A (en) 1979-07-28
ES471778A1 (es) 1979-02-01
FI782238A (fi) 1979-06-30
NO149960B (no) 1984-04-16

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