CS114290A3 - Specifically glycosylated insulin derivatives - Google Patents
Specifically glycosylated insulin derivatives Download PDFInfo
- Publication number
- CS114290A3 CS114290A3 CS901142A CS114290A CS114290A3 CS 114290 A3 CS114290 A3 CS 114290A3 CS 901142 A CS901142 A CS 901142A CS 114290 A CS114290 A CS 114290A CS 114290 A3 CS114290 A3 CS 114290A3
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- insulin
- glycosylated insulin
- residues
- specifically
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK111489A DK111489D0 (da) | 1989-03-08 | 1989-03-08 | Peptider |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS114290A3 true CS114290A3 (en) | 1992-02-19 |
Family
ID=8101165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS901142A CS114290A3 (en) | 1989-03-08 | 1990-03-08 | Specifically glycosylated insulin derivatives |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0462192A1 (de) |
| JP (1) | JPH04504117A (de) |
| KR (1) | KR920701249A (de) |
| CN (1) | CN1045586A (de) |
| AU (1) | AU638701B2 (de) |
| CA (1) | CA2049937A1 (de) |
| CS (1) | CS114290A3 (de) |
| DD (1) | DD296933A5 (de) |
| DK (1) | DK111489D0 (de) |
| FI (1) | FI914226A0 (de) |
| GR (1) | GR1000604B (de) |
| HU (1) | HUT59942A (de) |
| IL (1) | IL93674A0 (de) |
| NO (1) | NO913517L (de) |
| NZ (1) | NZ232808A (de) |
| PT (1) | PT93366A (de) |
| WO (1) | WO1990010645A1 (de) |
| YU (1) | YU45490A (de) |
| ZA (1) | ZA901737B (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2552043A1 (en) | 2004-01-21 | 2005-08-04 | Novo Nordisk A/S | Transglutaminase mediated conjugation of peptides |
| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| US8846103B2 (en) | 2009-01-28 | 2014-09-30 | Smartcells, Inc. | Exogenously triggered controlled release materials and uses thereof |
| WO2010088294A1 (en) | 2009-01-28 | 2010-08-05 | Smartcells, Inc. | Conjugate based systems for controlled drug delivery |
| CA2750269A1 (en) | 2009-01-28 | 2010-08-05 | Smartcells, Inc. | Crystalline insulin-conjugates |
| US8569231B2 (en) | 2009-03-20 | 2013-10-29 | Smartcells, Inc. | Soluble non-depot insulin conjugates and uses thereof |
| AU2010226243A1 (en) | 2009-03-20 | 2011-09-22 | Smartcells, Inc. | Terminally-functionalized conjugates and uses thereof |
| EP2598170A4 (de) | 2010-07-28 | 2016-07-06 | Smartcells Inc | Arzneimittel-liganden-konjugate, deren synthese und zwischenprodukte daraus |
| JP2013535467A (ja) | 2010-07-28 | 2013-09-12 | スマートセルズ・インコーポレイテツド | 組換えにより発現されたインスリンポリペプチドおよびその使用 |
| JP2013541500A (ja) | 2010-07-28 | 2013-11-14 | スマートセルズ・インコーポレイテツド | 組換えレクチン、結合部位修飾レクチンおよびそれらの用途 |
| US9624287B2 (en) | 2012-07-17 | 2017-04-18 | Case Western Reserve University | O-linked carbohydrate-modified insulin analogues |
| EP2877200B1 (de) * | 2012-07-17 | 2019-05-08 | Case Western Reserve University | O-verknüpfte kohlenhydratmodifizierte insulinanaloga |
| AU2013346624B2 (en) | 2012-11-13 | 2018-08-09 | Adocia | Quick-acting insulin formulation including a substituted anionic compound |
| CA2890048C (en) | 2012-12-03 | 2022-05-03 | Merck Sharp & Dohme Corp. | O-glycosylated carboxy terminal portion (ctp) peptide-based insulin and insulin analogues |
| JP6410790B2 (ja) | 2013-03-14 | 2018-10-24 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ミトコンドリアアルデヒドデヒドロゲナーゼ−２調節因子およびその使用方法 |
| AU2014329567B2 (en) | 2013-10-04 | 2019-07-25 | Merck Sharp & Dohme Corp. | Glucose-responsive insulin conjugates |
| US9795678B2 (en) | 2014-05-14 | 2017-10-24 | Adocia | Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound |
| FR3020947B1 (fr) | 2014-05-14 | 2018-08-31 | Adocia | Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations |
| FR3043557B1 (fr) | 2015-11-16 | 2019-05-31 | Adocia | Composition a action rapide d'insuline comprenant un citrate substitue |
| CN105709207A (zh) | 2016-01-29 | 2016-06-29 | 徐宝贞 | 一种用于治疗痛风的药物 |
| CN105535927A (zh) * | 2016-01-29 | 2016-05-04 | 山东中海制药有限公司 | 一种用于治疗流感、上呼吸道感染、病毒性肺炎的药物 |
| CN105597080A (zh) * | 2016-01-29 | 2016-05-25 | 程潜 | 一种用于治疗尿毒症和尿蛋白的药物 |
| CN109562185A (zh) | 2016-06-02 | 2019-04-02 | 赛诺菲 | 药剂与能够结合葡萄糖感应蛋白的部分的新颖缀合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3847890A (en) * | 1971-11-01 | 1974-11-12 | A Green | Acidic monosaccharide-substituted proteins |
| US4444683A (en) * | 1982-11-17 | 1984-04-24 | University Of Utah | Glycosylated insulin derivatives |
| EP0119650A3 (de) * | 1983-03-21 | 1987-09-30 | THE PROCTER & GAMBLE COMPANY | Galactosyl-Insulin-Konjugate für die Behandlung von Zuckerkranken |
| HU206890B (en) * | 1986-10-13 | 1993-01-28 | Sandoz Ag | Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components |
-
1989
- 1989-03-08 DK DK111489A patent/DK111489D0/da not_active Application Discontinuation
-
1990
- 1990-03-06 HU HU8727A patent/HUT59942A/hu unknown
- 1990-03-06 KR KR1019910701014A patent/KR920701249A/ko not_active Application Discontinuation
- 1990-03-06 NZ NZ232808A patent/NZ232808A/en unknown
- 1990-03-06 JP JP2504720A patent/JPH04504117A/ja active Pending
- 1990-03-06 AU AU52807/90A patent/AU638701B2/en not_active Expired - Fee Related
- 1990-03-06 EP EP19900904777 patent/EP0462192A1/de not_active Ceased
- 1990-03-06 CA CA002049937A patent/CA2049937A1/en not_active Abandoned
- 1990-03-06 WO PCT/DK1990/000062 patent/WO1990010645A1/en not_active Application Discontinuation
- 1990-03-07 ZA ZA901737A patent/ZA901737B/xx unknown
- 1990-03-07 CN CN90101282A patent/CN1045586A/zh active Pending
- 1990-03-07 GR GR900100159A patent/GR1000604B/el unknown
- 1990-03-07 DD DD90338488A patent/DD296933A5/de not_active IP Right Cessation
- 1990-03-07 IL IL93674A patent/IL93674A0/xx unknown
- 1990-03-07 YU YU00454/90A patent/YU45490A/xx unknown
- 1990-03-07 PT PT93366A patent/PT93366A/pt not_active Application Discontinuation
- 1990-03-08 CS CS901142A patent/CS114290A3/cs unknown
-
1991
- 1991-09-06 NO NO91913517A patent/NO913517L/no unknown
- 1991-09-06 FI FI914226A patent/FI914226A0/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| GR1000604B (el) | 1992-08-26 |
| CN1045586A (zh) | 1990-09-26 |
| AU638701B2 (en) | 1993-07-08 |
| AU5280790A (en) | 1990-10-09 |
| KR920701249A (ko) | 1992-08-11 |
| WO1990010645A1 (en) | 1990-09-20 |
| EP0462192A1 (de) | 1991-12-27 |
| NZ232808A (en) | 1992-04-28 |
| JPH04504117A (ja) | 1992-07-23 |
| GR900100159A (en) | 1990-07-31 |
| IL93674A0 (en) | 1990-12-23 |
| NO913517L (no) | 1991-11-06 |
| YU45490A (en) | 1991-10-31 |
| PT93366A (pt) | 1990-11-07 |
| NO913517D0 (no) | 1991-09-06 |
| DK111489D0 (da) | 1989-03-08 |
| HUT59942A (en) | 1992-07-28 |
| DD296933A5 (de) | 1991-12-19 |
| ZA901737B (en) | 1990-11-28 |
| CA2049937A1 (en) | 1990-09-09 |
| HU902787D0 (en) | 1991-11-28 |
| FI914226A0 (fi) | 1991-09-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CS114290A3 (en) | Specifically glycosylated insulin derivatives | |
| Spiro | Studies on the renal glomerular basement membrane: preparation and chemical composition | |
| Volpin et al. | Cyanogen bromide peptides from insoluble skin and dentin bovine collagens | |
| US9452224B2 (en) | Sialic acid derivatives for protein derivatisation and conjugation | |
| JP4416184B2 (ja) | 長期作用型薬物およびこれらを含む薬剤組成物 | |
| US6908897B2 (en) | Covalently bridged insulin dimers | |
| EP0119650A2 (de) | Galactosyl-Insulin-Konjugate für die Behandlung von Zuckerkranken | |
| MX2011000847A (es) | Proteinas conjugadas con eficacia prolongada in vivo. | |
| WO2005041865A2 (en) | Compounds and method for treating cancer | |
| IE910579A1 (en) | Novel protein compositions | |
| EP0128097B1 (de) | Immunostimulierende Derivate, ihre Herstellung und ihre Verwendung als Arzeimittel | |
| AU608512B2 (en) | Sulfated polysaccharide | |
| US6274558B1 (en) | Method for treating cardiac malfunction | |
| AU2008303584B2 (en) | Glycoproteins and glycosylated cells and a method for the preparation of the same | |
| Kozulić et al. | Study of the carbohydrate part of yeast acid phosphatase | |
| JP2018506576A (ja) | 多価リガンド−脂質構築物 | |
| Ito et al. | Structural study of the oligosaccharide moieties of sphingolipid activator proteins, saposins A, C and D obtained from the spleen of a Gaucher patient | |
| Goussault et al. | Chemical characterization of two urinary sialic acid-rich glycopeptides | |
| USRE32347E (en) | Hypocalcaemic peptides and process for their manufacture | |
| JPH09309842A (ja) | 新規な生理活性物質、その製造方法及び医薬組成物 | |
| JP2729201B2 (ja) | アミド結合を持ったシアル酸誘導体 | |
| Koeners et al. | Synthesis of 0-(2-0-α-d-glucopyranosyl)-β-d-galactopyranoside of optically pure δ-hydroxy-l-lysylglycine and-gd-hydroxy-l-lysylglycyl-l-glutamyl-l-aspartylglycine: Components of the glomerular basement membrane | |
| Vicari et al. | Immunochemical studies on blood groups. XLV. Structures and activities of oligosaccharides produced by alkaline degradation of a blood group substance lacking A, B, H, Lea, and Leb specificities | |
| JP2714430B2 (ja) | Ｎａ，Ｋ―ＡＴＰａｓｅ阻害作用を有する新規ペプタイド | |
| US20040077845A1 (en) | Modifier |