KR920701249A - 글리코실화 인슐린 - Google Patents

글리코실화 인슐린

Info

Publication number
KR920701249A
KR920701249A KR1019910701014A KR910701014A KR920701249A KR 920701249 A KR920701249 A KR 920701249A KR 1019910701014 A KR1019910701014 A KR 1019910701014A KR 910701014 A KR910701014 A KR 910701014A KR 920701249 A KR920701249 A KR 920701249A
Authority
KR
South Korea
Prior art keywords
insulin
glycosylated
glycosylated insulin
less
group
Prior art date
Application number
KR1019910701014A
Other languages
English (en)
Korean (ko)
Inventor
브로베르크 할스트롬 요온
Original Assignee
안네 제케르
노보 노르디스크 아크티에 셀스카브
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 안네 제케르, 노보 노르디스크 아크티에 셀스카브 filed Critical 안네 제케르
Publication of KR920701249A publication Critical patent/KR920701249A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
KR1019910701014A 1989-03-08 1990-03-06 글리코실화 인슐린 KR920701249A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK111489A DK111489D0 (da) 1989-03-08 1989-03-08 Peptider
DK1114/89 1989-03-08
PCT/DK1990/000062 WO1990010645A1 (en) 1989-03-08 1990-03-06 Glycosylated insulins

Publications (1)

Publication Number Publication Date
KR920701249A true KR920701249A (ko) 1992-08-11

Family

ID=8101165

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910701014A KR920701249A (ko) 1989-03-08 1990-03-06 글리코실화 인슐린

Country Status (19)

Country Link
EP (1) EP0462192A1 (de)
JP (1) JPH04504117A (de)
KR (1) KR920701249A (de)
CN (1) CN1045586A (de)
AU (1) AU638701B2 (de)
CA (1) CA2049937A1 (de)
CS (1) CS114290A3 (de)
DD (1) DD296933A5 (de)
DK (1) DK111489D0 (de)
FI (1) FI914226A0 (de)
GR (1) GR1000604B (de)
HU (1) HUT59942A (de)
IL (1) IL93674A0 (de)
NO (1) NO913517L (de)
NZ (1) NZ232808A (de)
PT (1) PT93366A (de)
WO (1) WO1990010645A1 (de)
YU (1) YU45490A (de)
ZA (1) ZA901737B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103215328B (zh) 2004-01-21 2016-08-03 诺和诺德医疗保健公司 转谷氨酰胺酶介导的肽的接合
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
RU2011135730A (ru) 2009-01-28 2013-03-10 Смартселлз, Инк. Кристаллические инсулин-коньюгаты
WO2010088294A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Conjugate based systems for controlled drug delivery
WO2010088268A1 (en) 2009-01-28 2010-08-05 Smartcells, Inc. Exogenously triggered controlled release materials and uses thereof
US8623345B2 (en) 2009-03-20 2014-01-07 Smartcells Terminally-functionalized conjugates and uses thereof
WO2010107520A1 (en) 2009-03-20 2010-09-23 Smartcells, Inc. Soluble non-depot insulin conjugates and uses thereof
AU2011282988A1 (en) 2010-07-28 2013-01-31 Smartcells, Inc. Recombinantly expressed insulin polypeptides and uses thereof
JP2013541500A (ja) 2010-07-28 2013-11-14 スマートセルズ・インコーポレイテツド 組換えレクチン、結合部位修飾レクチンおよびそれらの用途
CA2805739A1 (en) 2010-07-28 2012-02-02 Smartcells, Inc. Drug-ligand conjugates, synthesis thereof, and intermediates thereto
US9624287B2 (en) 2012-07-17 2017-04-18 Case Western Reserve University O-linked carbohydrate-modified insulin analogues
WO2014015078A1 (en) * 2012-07-17 2014-01-23 Michael Weiss O-linked carbohydrate-modified insulin analogues
EP3332810B1 (de) 2012-11-13 2021-01-13 Adocia Insulin-formulierung mit schneller wirkung, die eine substituierte anionische verbindung umfasst
US9707276B2 (en) 2012-12-03 2017-07-18 Merck Sharp & Dohme Corp. O-glycosylated carboxy terminal portion (CTP) peptide-based insulin and insulin analogues
CN105358531B (zh) 2013-03-14 2017-11-14 利兰-斯坦福大学初级学院的董事会 线粒体醛脱氢酶‑2调节剂和其使用方法
BR112016007176A2 (pt) 2013-10-04 2018-01-23 Merck Sharp & Dohme conjugado, composição, usos de um conjugado e de uma composição, e, método para tratar um indivíduo que tem diabete
US9795678B2 (en) 2014-05-14 2017-10-24 Adocia Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound
FR3020947B1 (fr) 2014-05-14 2018-08-31 Adocia Composition aqueuse comprenant au moins une proteine et un agent solubilisant, sa preparation et ses utilisations
FR3043557B1 (fr) 2015-11-16 2019-05-31 Adocia Composition a action rapide d'insuline comprenant un citrate substitue
CN105535927A (zh) * 2016-01-29 2016-05-04 山东中海制药有限公司 一种用于治疗流感、上呼吸道感染、病毒性肺炎的药物
CN105709207A (zh) * 2016-01-29 2016-06-29 徐宝贞 一种用于治疗痛风的药物
CN105597080A (zh) * 2016-01-29 2016-05-25 程潜 一种用于治疗尿毒症和尿蛋白的药物
EP3463480A1 (de) 2016-06-02 2019-04-10 Sanofi Konjugate eines pharmazeutischen mittels und eines teils mit fähigkeit zur bindung an ein glucoseerfassendes protein

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3847890A (en) * 1971-11-01 1974-11-12 A Green Acidic monosaccharide-substituted proteins
US4444683A (en) * 1982-11-17 1984-04-24 University Of Utah Glycosylated insulin derivatives
EP0119650A3 (de) * 1983-03-21 1987-09-30 THE PROCTER & GAMBLE COMPANY Galactosyl-Insulin-Konjugate für die Behandlung von Zuckerkranken
HU206890B (en) * 1986-10-13 1993-01-28 Sandoz Ag Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components

Also Published As

Publication number Publication date
AU5280790A (en) 1990-10-09
JPH04504117A (ja) 1992-07-23
EP0462192A1 (de) 1991-12-27
GR900100159A (en) 1990-07-31
NZ232808A (en) 1992-04-28
DD296933A5 (de) 1991-12-19
IL93674A0 (en) 1990-12-23
WO1990010645A1 (en) 1990-09-20
HU902787D0 (en) 1991-11-28
FI914226A0 (fi) 1991-09-06
GR1000604B (el) 1992-08-26
NO913517D0 (no) 1991-09-06
ZA901737B (en) 1990-11-28
NO913517L (no) 1991-11-06
PT93366A (pt) 1990-11-07
AU638701B2 (en) 1993-07-08
CN1045586A (zh) 1990-09-26
CS114290A3 (en) 1992-02-19
DK111489D0 (da) 1989-03-08
CA2049937A1 (en) 1990-09-09
YU45490A (en) 1991-10-31
HUT59942A (en) 1992-07-28

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Legal Events

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WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid