CR20140545A - Piperazino[1,2-a]indol-1-onas y [1,4]diazepino [1,2-a]indol-1-ona - Google Patents

Piperazino[1,2-a]indol-1-onas y [1,4]diazepino [1,2-a]indol-1-ona

Info

Publication number
CR20140545A
CR20140545A CR20140545A CR20140545A CR20140545A CR 20140545 A CR20140545 A CR 20140545A CR 20140545 A CR20140545 A CR 20140545A CR 20140545 A CR20140545 A CR 20140545A CR 20140545 A CR20140545 A CR 20140545A
Authority
CR
Costa Rica
Prior art keywords
indol
diazepino
onas
piperazino
ona
Prior art date
Application number
CR20140545A
Other languages
English (en)
Inventor
Simona M Ceccarelli
Ravi Jagasia
Roland Jakob-Roetne
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CR20140545A publication Critical patent/CR20140545A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

La presente invención se refiere a compuestos de la fórmula general I:
CR20140545A 2012-08-06 2014-11-27 Piperazino[1,2-a]indol-1-onas y [1,4]diazepino [1,2-a]indol-1-ona CR20140545A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12179381 2012-08-06
PCT/EP2013/066344 WO2014023674A1 (en) 2012-08-06 2013-08-05 Piperazino[1,2-a]indol-1-ones and [1,4]diazepino[1,2-a]indol-1-one

Publications (1)

Publication Number Publication Date
CR20140545A true CR20140545A (es) 2015-01-12

Family

ID=48918402

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20140545A CR20140545A (es) 2012-08-06 2014-11-27 Piperazino[1,2-a]indol-1-onas y [1,4]diazepino [1,2-a]indol-1-ona

Country Status (25)

Country Link
US (1) US9284321B2 (es)
EP (1) EP2880036B1 (es)
JP (1) JP5974177B2 (es)
KR (1) KR101716062B1 (es)
CN (1) CN104540829B (es)
AR (1) AR092041A1 (es)
AU (1) AU2013301577B2 (es)
BR (1) BR112015000313A2 (es)
CA (1) CA2880682A1 (es)
CL (1) CL2015000143A1 (es)
CO (1) CO7141435A2 (es)
CR (1) CR20140545A (es)
EA (1) EA025884B1 (es)
HK (1) HK1206355A1 (es)
IL (1) IL236808B (es)
MA (1) MA37791B1 (es)
MX (1) MX362184B (es)
MY (1) MY185216A (es)
NZ (1) NZ703192A (es)
PE (1) PE20150341A1 (es)
PH (1) PH12015500059A1 (es)
SG (1) SG11201408529VA (es)
TW (1) TWI506027B (es)
UA (1) UA113013C2 (es)
WO (1) WO2014023674A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4089397A1 (en) * 2013-02-18 2022-11-16 Labrador Diagnostics LLC System for optically analyzing a sample
TW201443056A (zh) 2013-04-02 2014-11-16 Hoffmann La Roche 哌□并［１，２－ａ］吲哚－１－酮及［１，４］二氮呯并［１，２－ａ］吲哚－１－酮
MX2016001528A (es) * 2013-09-12 2016-06-23 Hoffmann La Roche Derivados de indol-carboxamida.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1965981C3 (de) * 1968-02-13 1978-08-31 Sumitomo Chemical Co., Ltd., Osaka (Japan) 9-Phenyl-lO-oxopiperazino [l,2-a]-indole und Verfahren zu ihrer Herstellung
GB0106177D0 (en) * 2001-03-13 2001-05-02 Hoffmann La Roche Piperazine derivatives
GB0202015D0 (en) * 2002-01-29 2002-03-13 Hoffmann La Roche Piperazine Derivatives
ES2333672T3 (es) * 2005-12-09 2010-02-25 F. Hoffmann-La Roche Ag Derivados de amida triciclica para tratamiento de obesidad.
WO2008046072A2 (en) 2006-10-13 2008-04-17 The Board Of Regents Of The University Of Texas System Chemical inducers of neurogenesis
MX2009004898A (es) * 2006-11-09 2009-05-19 Hoffmann La Roche Derivados de indol y de benzofurano-2-carboxamida.
BR112013000414A2 (pt) 2010-07-07 2016-05-17 Univ Texas compostos proneurogênicos
TW201443056A (zh) * 2013-04-02 2014-11-16 Hoffmann La Roche 哌□并［１，２－ａ］吲哚－１－酮及［１，４］二氮呯并［１，２－ａ］吲哚－１－酮

Also Published As

Publication number Publication date
EP2880036A1 (en) 2015-06-10
NZ703192A (en) 2016-04-29
PH12015500059B1 (en) 2015-03-02
CA2880682A1 (en) 2014-02-13
CN104540829B (zh) 2017-04-26
BR112015000313A2 (pt) 2017-06-27
MA37791A1 (fr) 2016-05-31
CO7141435A2 (es) 2014-12-12
PH12015500059A1 (en) 2015-03-02
MY185216A (en) 2021-04-30
EA201590125A1 (ru) 2015-05-29
JP5974177B2 (ja) 2016-08-23
TW201410679A (zh) 2014-03-16
UA113013C2 (uk) 2016-11-25
AU2013301577B2 (en) 2017-03-30
SG11201408529VA (en) 2015-01-29
MX362184B (es) 2019-01-08
EA025884B1 (ru) 2017-02-28
KR20150027832A (ko) 2015-03-12
CN104540829A (zh) 2015-04-22
KR101716062B1 (ko) 2017-03-13
US9284321B2 (en) 2016-03-15
MX2015001318A (es) 2015-04-17
JP2015524456A (ja) 2015-08-24
TWI506027B (zh) 2015-11-01
EP2880036B1 (en) 2017-03-08
PE20150341A1 (es) 2015-02-28
AU2013301577A1 (en) 2014-12-18
CL2015000143A1 (es) 2015-06-19
IL236808B (en) 2018-05-31
WO2014023674A1 (en) 2014-02-13
MA37791B1 (fr) 2016-12-30
HK1206355A1 (en) 2016-01-08
US20150246922A1 (en) 2015-09-03
AR092041A1 (es) 2015-03-18

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