CR20120087A - Anticuerpos del antígeno carcinoembrionario (cea) - Google Patents

Anticuerpos del antígeno carcinoembrionario (cea)

Info

Publication number
CR20120087A
CR20120087A CR20120087A CR20120087A CR20120087A CR 20120087 A CR20120087 A CR 20120087A CR 20120087 A CR20120087 A CR 20120087A CR 20120087 A CR20120087 A CR 20120087A CR 20120087 A CR20120087 A CR 20120087A
Authority
CR
Costa Rica
Prior art keywords
abms
relates
present
antibodies
cea
Prior art date
Application number
CR20120087A
Other languages
English (en)
Spanish (es)
Inventor
Thomas U Hofer
Ralf Hosse
Ekkehard Moessner
Pablo Umana
Original Assignee
Roche Glycart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42985489&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR20120087(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Glycart Ag filed Critical Roche Glycart Ag
Publication of CR20120087A publication Critical patent/CR20120087A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007Carcino-embryonic Antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CR20120087A 2009-08-31 2012-02-20 Anticuerpos del antígeno carcinoembrionario (cea) CR20120087A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23850509P 2009-08-31 2009-08-31

Publications (1)

Publication Number Publication Date
CR20120087A true CR20120087A (es) 2012-03-22

Family

ID=42985489

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20120087A CR20120087A (es) 2009-08-31 2012-02-20 Anticuerpos del antígeno carcinoembrionario (cea)

Country Status (22)

Country Link
US (2) US9068008B2 (enExample)
EP (1) EP2473532B1 (enExample)
JP (1) JP5744872B2 (enExample)
KR (1) KR101528013B1 (enExample)
CN (1) CN102741293B (enExample)
AR (1) AR078111A1 (enExample)
AU (1) AU2010288469A1 (enExample)
BR (1) BR112012003983A2 (enExample)
CA (1) CA2770174A1 (enExample)
CL (1) CL2012000551A1 (enExample)
CO (1) CO6491105A2 (enExample)
CR (1) CR20120087A (enExample)
EC (1) ECSP12011698A (enExample)
IL (1) IL218038A0 (enExample)
MA (1) MA33536B1 (enExample)
MX (1) MX339608B (enExample)
PE (1) PE20121552A1 (enExample)
RU (1) RU2570554C2 (enExample)
SG (1) SG178567A1 (enExample)
TW (1) TW201121994A (enExample)
WO (1) WO2011023787A1 (enExample)
ZA (1) ZA201200954B (enExample)

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HUE029139T2 (hu) 2011-02-10 2017-02-28 Roche Glycart Ag Mutáns interleukin-2 polipeptidek
HRP20180147T1 (hr) * 2011-03-02 2018-02-23 Roche Glycart Ag Cea protutijela
EA201892619A1 (ru) * 2011-04-29 2019-04-30 Роше Гликарт Аг Иммуноконъюгаты, содержащие мутантные полипептиды интерлейкина-2
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EA031214B1 (ru) 2013-02-26 2018-12-28 Роше Гликарт Аг Биспецифические антигенсвязывающие молекулы, активирующие т-клетки
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JP6944369B2 (ja) 2014-11-20 2021-10-06 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト T細胞活性化二重特異性抗原結合分子cd3 abd葉酸受容体1(folr1)及びpd−1軸結合アンタゴニストの併用療法
PT3221357T (pt) 2014-11-20 2020-07-28 Hoffmann La Roche Cadeias leves comuns e métodos de utilização
MA40972B1 (fr) 2014-11-20 2020-11-30 Hoffmann La Roche Molécules bispécifiques de liaison à l'antigène activant les lymphocytes t ciblant folr1 et cd3
AR106188A1 (es) 2015-10-01 2017-12-20 Hoffmann La Roche Anticuerpos anti-cd19 humano humanizados y métodos de utilización
MA43025A (fr) 2015-10-02 2021-05-26 Hoffmann La Roche Molécules bispécifiques de liaison à l'antigène activant les lymphocytes t anti-ceaxcd3
PL3387015T3 (pl) 2015-12-09 2022-02-14 F. Hoffmann-La Roche Ag Przeciwciało anty-CD20 typu II do ograniczania tworzenia przeciwciał przeciwlekowych
JP6949030B2 (ja) 2016-01-08 2021-10-13 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Pd−1軸結合アンタゴニスト及び抗cea/抗cd3二重特異性抗体を用いたcea陽性がんの治療方法
RS64266B1 (sr) 2016-03-22 2023-07-31 Hoffmann La Roche Bispecifični molekul koji aktivira t ćeliju koji se aktivira proteazom
CN107663240B (zh) * 2016-07-29 2021-01-12 中国人民解放军第四军医大学 高度糖基化cea特异性结合的单链抗体及其在检测和治疗上的应用
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WO2020259550A1 (zh) * 2019-06-26 2020-12-30 江苏恒瑞医药股份有限公司 抗cea抗体及其应用
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CN110862456B (zh) * 2019-09-23 2021-04-09 华道(上海)生物医药有限公司 一种抗癌胚抗原的抗体及其制备方法和用途
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KR102859548B1 (ko) 2020-08-20 2025-09-12 에이투 바이오쎄라퓨틱스, 인크. 메소텔린 양성 암을 치료하기 위한 조성물 및 방법
KR20240005691A (ko) 2021-04-30 2024-01-12 에프. 호프만-라 로슈 아게 항-cd20/항-cd3 이중특이적 항체 및 항-cd79b 항체 약물 접합체를 이용한 병용 치료를 위한 투약
TW202307004A (zh) * 2021-05-21 2023-02-16 英屬開曼群島商百濟神州有限公司 抗cea抗體及使用方法
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Also Published As

Publication number Publication date
KR20120060874A (ko) 2012-06-12
JP5744872B2 (ja) 2015-07-08
ECSP12011698A (es) 2012-03-30
ZA201200954B (en) 2014-07-30
AR078111A1 (es) 2011-10-12
CL2012000551A1 (es) 2012-10-12
PE20121552A1 (es) 2012-11-26
MX339608B (es) 2016-05-31
MA33536B1 (fr) 2012-08-01
IL218038A0 (en) 2012-04-30
US9068008B2 (en) 2015-06-30
WO2011023787A1 (en) 2011-03-03
SG178567A1 (en) 2012-04-27
CN102741293A (zh) 2012-10-17
HK1176951A1 (en) 2013-08-09
MX2012002461A (es) 2012-03-14
CN102741293B (zh) 2015-04-01
RU2570554C2 (ru) 2015-12-10
CA2770174A1 (en) 2011-03-03
EP2473532B1 (en) 2017-06-21
US20160075795A1 (en) 2016-03-17
EP2473532A1 (en) 2012-07-11
BR112012003983A2 (pt) 2021-09-14
KR101528013B1 (ko) 2015-06-16
JP2013502913A (ja) 2013-01-31
TW201121994A (en) 2011-07-01
AU2010288469A1 (en) 2012-03-01
CO6491105A2 (es) 2012-07-31
US20110104148A1 (en) 2011-05-05
RU2012112340A (ru) 2013-10-10

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