CR20110628A - Piperidinas sustituidas - Google Patents

Piperidinas sustituidas

Info

Publication number
CR20110628A
CR20110628A CR20110628A CR20110628A CR20110628A CR 20110628 A CR20110628 A CR 20110628A CR 20110628 A CR20110628 A CR 20110628A CR 20110628 A CR20110628 A CR 20110628A CR 20110628 A CR20110628 A CR 20110628A
Authority
CR
Costa Rica
Prior art keywords
piperidins
substituted
prophylaxis
diseases
treatment
Prior art date
Application number
CR20110628A
Other languages
English (en)
Inventor
Dirk Heimbach
Susanne Roehrig
Grande Yolanda Cancho
Eckhard Bender
Katja Zimmermann
Anja Buchmueller
Christoph Gerdes
Mark Jean Gnoth
Kersten Matthias Gericke
Mario Jeske
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CR20110628A publication Critical patent/CR20110628A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Non-Alcoholic Beverages (AREA)

Abstract

La invención se refiere a nuevas piperidinas sustituidas, a procedimientos para su preparación, al uso de las mismas para tratamiento y/o profilaxis de enfermedades y al uso de las mismas para la producción de medicamentos para tratamiento y/o profilaxis de enfermedades, especialmente de trastornos cardiovasculares y trastornos tumorales.
CR20110628A 2009-05-27 2011-11-24 Piperidinas sustituidas CR20110628A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102009022896A DE102009022896A1 (de) 2009-05-27 2009-05-27 Substituierte Piperidine

Publications (1)

Publication Number Publication Date
CR20110628A true CR20110628A (es) 2012-03-22

Family

ID=42543057

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20110628A CR20110628A (es) 2009-05-27 2011-11-24 Piperidinas sustituidas

Country Status (28)

Country Link
US (2) US20120220563A1 (es)
EP (1) EP2435427A1 (es)
JP (1) JP5718320B2 (es)
KR (1) KR20120044289A (es)
CN (2) CN102596944B (es)
AR (1) AR076692A1 (es)
AU (1) AU2010252345A1 (es)
BR (1) BRPI1012055A2 (es)
CA (1) CA2763400A1 (es)
CL (1) CL2011002965A1 (es)
CO (1) CO6470823A2 (es)
CR (1) CR20110628A (es)
CU (1) CU20110215A7 (es)
DE (1) DE102009022896A1 (es)
DO (1) DOP2011000364A (es)
EA (1) EA201190312A1 (es)
EC (2) ECSP11011483A (es)
GT (1) GT201100300A (es)
IL (1) IL215901A0 (es)
MA (1) MA33290B1 (es)
MX (1) MX2011012505A (es)
PE (1) PE20120934A1 (es)
SG (1) SG175753A1 (es)
TN (1) TN2011000595A1 (es)
TW (1) TW201109326A (es)
UY (2) UY32636A (es)
WO (1) WO2010136144A1 (es)
ZA (1) ZA201108565B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009014484A1 (de) 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022892A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
BR112014007257B1 (pt) 2011-10-07 2023-04-25 Takeda Pharmaceutical Company Limited Composto 1-arilcarbonil-4-oxi-piperidina
AU2017252546B2 (en) 2016-04-20 2021-07-29 Bristol-Myers Squibb Company Substituted bicyclic heterocyclic compounds
SG11201903871TA (en) 2016-11-03 2019-05-30 Bristol Myers Squibb Co Substituted bicycle heterocyclic derivatives useful as romk channel inhibitors
PL3630752T3 (pl) 2017-06-01 2021-11-02 Bristol-Myers Squibb Company Podstawione związki zawierające azot
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5767144A (en) * 1994-08-19 1998-06-16 Abbott Laboratories Endothelin antagonists
WO1997036873A1 (en) 1996-04-03 1997-10-09 Merck & Co., Inc. Piperidines, pyrrolidines and hexahydro-1h-azepines promote release of growth hormone
US6403612B2 (en) * 2000-01-31 2002-06-11 Merck & Co., Inc. Thrombin receptor antagonists
ATE345799T1 (de) 2001-10-15 2006-12-15 Janssen Pharmaceutica Nv Substituierte 4-phenyl-4-(1h-imidazol-2-yl)- piperidinderivate zur verringerung von ischämischer schädigung
WO2003074495A1 (en) * 2002-03-01 2003-09-12 Smithkline Beecham Corporation Hppars activators
WO2006002349A1 (en) 2004-06-24 2006-01-05 Incyte Corporation Amido compounds and their use as pharmaceuticals
MXPA06014574A (es) * 2004-06-24 2007-03-12 Incyte Corp Piperidinas n-sustituidas y su uso como farmaceuticos.
CN1993128A (zh) * 2004-06-24 2007-07-04 因塞特公司 N－取代的哌啶及它们作为药物的用途
JP2008504279A (ja) 2004-06-24 2008-02-14 インサイト・コーポレイション アミド化合物およびその医薬としての使用
EA200700251A1 (ru) 2004-08-10 2007-08-31 Инсайт Корпорейшн Амидосоединения и их применение в качестве фармацевтических средств
JP2007008913A (ja) * 2004-09-17 2007-01-18 Tanabe Seiyaku Co Ltd ピペリジン化合物およびその製法
DE102004045796A1 (de) * 2004-09-22 2006-03-23 Merck Patent Gmbh Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung
DE102004061750A1 (de) * 2004-12-22 2006-07-06 Bayer Healthcare Ag Heteroaryl-substituierte Pyrazoline
CA2621255A1 (en) 2005-09-21 2007-04-05 Incyte Corporation Amido compounds and their use as pharmaceuticals
WO2007089683A1 (en) 2006-01-31 2007-08-09 Incyte Corporation Amido compounds and their use as pharmaceuticals
TW200808807A (en) 2006-03-02 2008-02-16 Incyte Corp Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
WO2007130898A1 (en) 2006-05-01 2007-11-15 Incyte Corporation TETRASUBSTITUTED UREAS AS MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1
DK2227466T3 (da) 2007-11-30 2011-08-08 Bayer Schering Pharma Ag Heteroaryl-substituerede piperidiner
DE102009014484A1 (de) * 2009-03-23 2010-09-30 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022896A1 (de) 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022897A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine
DE102009022894A1 (de) * 2009-05-27 2010-12-02 Bayer Schering Pharma Aktiengesellschaft Substituierte Piperidine

Also Published As

Publication number Publication date
UY32636A (es) 2010-12-31
JP5718320B2 (ja) 2015-05-13
KR20120044289A (ko) 2012-05-07
US8084469B2 (en) 2011-12-27
JP2012528090A (ja) 2012-11-12
EA201190312A1 (ru) 2012-05-30
DOP2011000364A (es) 2012-02-29
GT201100300A (es) 2013-08-21
DE102009022896A1 (de) 2010-12-02
TW201109326A (en) 2011-03-16
UY32638A (es) 2010-10-29
AR076692A1 (es) 2011-06-29
US20120220563A1 (en) 2012-08-30
CN102596944A (zh) 2012-07-18
BRPI1012055A2 (pt) 2016-05-17
ZA201108565B (en) 2013-01-30
ECSP11011483A (es) 2011-12-30
CN104744452A (zh) 2015-07-01
TN2011000595A1 (en) 2013-05-24
AU2010252345A1 (en) 2011-12-08
CO6470823A2 (es) 2012-06-29
PE20120934A1 (es) 2012-08-01
CA2763400A1 (en) 2010-12-02
SG175753A1 (en) 2011-12-29
EP2435427A1 (de) 2012-04-04
IL215901A0 (en) 2012-01-31
CN102596944B (zh) 2015-08-26
MX2011012505A (es) 2011-12-14
CU20110215A7 (es) 2012-03-15
CL2011002965A1 (es) 2012-07-06
WO2010136144A1 (de) 2010-12-02
ECSP11011482A (es) 2011-12-30
MA33290B1 (fr) 2012-05-02
US20110021489A1 (en) 2011-01-27

Similar Documents

Publication Publication Date Title
CU20110215A7 (es) Piperidinas sustituidas
PA8784001A1 (es) Oxazolidinonas sustituidas y su uso
CY1117372T1 (el) Υποκατεστημενες 5-φθορο-1η-πυραζολοπυριδινες και η χρηση τους
DK3045456T3 (da) Bicyklisk substituerede uraciler og anvendelse heraf
DOP2009000205A (es) 4-aril-1,4-dihidro-1,6-naftiridinamidas sustituidas y su uso
TN2011000466A1 (en) Substituted 2-acetamido -5-aryl-1, 2, 4- triazolones and use thereof
WO2013151665A3 (en) Modified polynucleotides for the production of proteins associated with human disease
GT200900095A (es) Dihidropirazolonas sustituidas para el tratamiento de enfermedades cardiovasculares y hermatologicas.
EA201200551A1 (ru) Фармацевтическая композиция, фармацевтическая дозированная форма, способы их получения и применения для лечения
EA201491028A1 (ru) Способ получения замещенных 5-фтор-1н-пиразолопиридинов
DK2243772T3 (da) Hidtil ukendte P2X7R-antagonister og deres anvendelse
ATE523510T1 (de) Substituierte 4-aryl-1,4-dihydro-1,6- naphthyridine und ihre verwendung
CO6470822A2 (es) Piperidinas susituidas
MY150931A (en) Substituted oxazolidinones and their use
UY35746A (es) Derivados de fenilalanina sustituidos
DE502007006625D1 (de) 3-cyano-5-thiazaheteroaryl-dihydropyridine und ihrnkungen
MX2013002261A (es) N-fenetiltriazolonacetamidas sustituidas y su uso.
CL2008001690A1 (es) Compuestos derivados de oxazolidinonas; su procedimiento de preparacion; y sus usos para preparar un medicamento.
BR112013006307A2 (pt) fenilacetamidas e fenilpropanamidas substituídas e o seu uso
DOP2005000174A (es) Fenilaminotiazoles sustituidos y su uso
TN2013000243A1 (en) Substituted 1-benzylcycloalkylcarboxlic acids and use thereof
UA111139C2 (uk) Тверді фармацевтичні композиції і способи їхнього отримання