CR10260A - - Google Patents

Info

Publication number
CR10260A
CR10260A CR10260A CR10260A CR10260A CR 10260 A CR10260 A CR 10260A CR 10260 A CR10260 A CR 10260A CR 10260 A CR10260 A CR 10260A CR 10260 A CR10260 A CR 10260A
Authority
CR
Costa Rica
Application number
CR10260A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of CR10260A publication Critical patent/CR10260A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CR10260A 2006-03-15 2008-08-28 CR10260A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB2006050812 2006-03-15

Publications (1)

Publication Number Publication Date
CR10260A true CR10260A (fr) 2008-10-03

Family

ID=38181192

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10260A CR10260A (fr) 2006-03-15 2008-08-28

Country Status (16)

Country Link
US (1) US20090082394A1 (fr)
EP (1) EP1998774A1 (fr)
JP (3) JP4582722B2 (fr)
KR (1) KR101065239B1 (fr)
CN (1) CN101400348A (fr)
AU (1) AU2007226203A1 (fr)
BR (1) BRPI0708913A2 (fr)
CA (1) CA2644010A1 (fr)
CR (1) CR10260A (fr)
EA (1) EA015256B1 (fr)
IL (1) IL194044A0 (fr)
MA (1) MA30327B1 (fr)
MX (1) MX2008011647A (fr)
NO (1) NO20084253L (fr)
UA (1) UA93903C2 (fr)
WO (1) WO2007105177A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118548A1 (fr) 2004-03-01 2005-12-15 Actelion Pharmaceuticals Ltd Derives de 1,2,3,4-tétrahydroisoquinoléine substitués
JP4582722B2 (ja) * 2006-03-15 2010-11-17 アクテリオン ファーマシューティカルズ リミテッド 記憶機能を向上させるテトラヒドロイソキノリン誘導体
CA2647077A1 (fr) * 2006-04-26 2007-11-01 Actelion Pharmaceuticals Ltd Nouveaux derives de pyrazolo-tetrahydropyridine
WO2008078291A1 (fr) 2006-12-22 2008-07-03 Actelion Pharmaceuticals Ltd Dérivés de 5,6,7,8-tétrahydro-imidazo[1,5-a]pyrazine
WO2008122513A1 (fr) * 2007-04-04 2008-10-16 F. Hoffmann-La Roche Ag Composés hétérocycliques en tant qu'antagonistes des récepteurs d'orexine
PE20091010A1 (es) * 2007-10-10 2009-08-08 Actelion Pharmaceuticals Ltd Derivados de tetrahidroquinolina
WO2009079637A1 (fr) 2007-12-18 2009-06-25 Concert Pharmaceuticals, Inc. Dérivés de tétrahydroisoquinoline
CA2709694C (fr) 2007-12-28 2016-04-05 Actelion Pharmaceuticals Ltd Compose 3,4-dihydro-1h-isoquinoleine trisubstituee, methode de preparation, et son utilisation
EP2307417A2 (fr) 2008-06-25 2011-04-13 Actelion Pharmaceuticals Ltd. Composés de 5,6,7,8-tétrahydro-imidazo[1,5-a]pyrazine
WO2010095106A1 (fr) 2009-02-20 2010-08-26 Actelion Pharmaceuticals Ltd Formes solides de chlorhydrate de( 2r)-2-{(is)-6, 7-diméthoxy- 1-[2- (4-trifluorométhyl-phényl)-éthyl]-3, 4-dihydro-1h-isoquinolin-2-yl}-n-méthyl-2-phényl acétamide
EP2608787B1 (fr) 2010-08-24 2019-11-20 Idorsia Pharmaceuticals Ltd Dérivés de proline sulfonamide comme antagonistes des récepteurs de l'orexine
UA108510C2 (en) 2010-09-22 2015-05-12 Eisai R&D Man Co Ltd Cyclopropane compound
WO2012063207A1 (fr) 2010-11-10 2012-05-18 Actelion Pharmaceuticals Ltd Dérivés de lactame utiles en tant qu'antagonistes du récepteur de l'orexine
WO2012085852A1 (fr) 2010-12-22 2012-06-28 Actelion Pharmaceuticals Ltd 3,8-diaza-bicyclo[4.2.0]oct-8-ylamides
JP5987005B2 (ja) 2011-02-18 2016-09-06 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ オレキシン拮抗薬として有用な新規なピラゾール及びイミダゾール誘導体
WO2012114252A1 (fr) 2011-02-21 2012-08-30 Actelion Pharmaceuticals Ltd Nouveaux amides d'indole et de pyrrolopyridine
WO2013050938A1 (fr) 2011-10-04 2013-04-11 Actelion Pharmaceuticals Ltd Dérivés de 3,7-diazabicyclo[3.3.1]nonane et de 9-oxa-3,7- diazabicyclo[3.3.1]nonane
DK2776430T3 (en) 2011-11-08 2016-05-09 Actelion Pharmaceuticals Ltd 2- (1,2,3-triazol-2-yl) benzamide and 3- (1,2,3-triazol-2-yl) PICOLINAMIDDERIVATER AS orexin receptor antagonists
US9732075B2 (en) 2012-06-04 2017-08-15 Idorsia Pharmaceuticals Ltd Benzimidazole-proline derivatives
JP6244365B2 (ja) 2012-10-10 2017-12-06 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ ［オルトビ−（ヘテロ−）アリール］−［２−（メタビ−（ヘテロ−）アリール）−ピロリジン−１−イル］−メタノン誘導体であるオレキシン受容体アンタゴニスト
WO2014141065A1 (fr) 2013-03-12 2014-09-18 Actelion Pharmaceuticals Ltd Dérivés d'amide d'azétidine en tant qu'antagonistes des récepteurs d'oréxine
UA119151C2 (uk) 2013-12-03 2019-05-10 Ідорсія Фармасьютікалз Лтд КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА
SI3077389T1 (en) 2013-12-03 2018-01-31 Idorsia Pharmaceuticals Ltd (S) - (2- (6-CHLORO-7-METHYL-1 H-BENZO (D) IMIDAZOL-2-YL) -2-METHYLPYROLIDIN-1-YL (5-METHOXY-2- (2H- , 2,3-TRIAZOL-2-IL) PHENYL) METHANONE AND ITS USE AS ANTAGONISTS OF OREXIN RECEPTOR
WO2015083094A1 (fr) 2013-12-04 2015-06-11 Actelion Pharmaceuticals Ltd Utilisation de dérivés de benzimidazole-proline
US10188652B2 (en) 2014-10-23 2019-01-29 Eisai R&D Management Co., Ltd. Compositions and methods for treating insomnia
WO2020007964A1 (fr) 2018-07-05 2020-01-09 Idorsia Pharmaceuticals Ltd Dérivés de 2-(2-azabicyclo [3.1.0] hexan-1-yl)-1h-benzimidazole
WO2020007977A1 (fr) 2018-07-06 2020-01-09 Idorsia Pharmaceuticals Ltd Dérivés de 7-trifluorométhyl-[1,4]diazépane
WO2020099511A1 (fr) 2018-11-14 2020-05-22 Idorsia Pharmaceuticals Ltd Dérivés de benzimidazole-2-méthyl-morpholine
TW202400149A (zh) 2022-05-13 2024-01-01 瑞士商愛杜西亞製藥有限公司 經噻唑并芳基-甲基取代之環狀肼-n-甲醯胺衍生物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703050B1 (fr) * 1993-03-24 1995-04-28 Adir Nouveaux dérivés bicycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
GB9319732D0 (en) * 1993-09-24 1993-11-10 Ucb Sa Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
JP3942207B2 (ja) * 1995-02-17 2007-07-11 武田薬品工業株式会社 うつ性症状改善剤
ES2234840T3 (es) * 2000-03-14 2005-07-01 Actelion Pharmaceuticals Ltd. Derivados de 1,2,3,4- tetrahidroisoquinolina.
EP1288202A4 (fr) * 2000-05-11 2003-07-02 Banyu Pharma Co Ltd Derives n-acyltetrahydroisoquinoline
WO2002051232A2 (fr) * 2000-12-27 2002-07-04 Actelion Pharmaceuticals Ltd. Nouvelles benzazepines et derives heterocycliques associes
NZ535885A (en) * 2002-04-26 2007-05-31 Hoffmann La Roche Isoquinoline derivatives and their use as monoamine oxidase B inhibitors
WO2004085403A1 (fr) 2003-03-26 2004-10-07 Actelion Pharmaceuticals Ltd Derives de tetrahydro-isoquinolyl-acetamide destines a servir d'antagonistes des recepteurs d'orexine
WO2005118548A1 (fr) * 2004-03-01 2005-12-15 Actelion Pharmaceuticals Ltd Derives de 1,2,3,4-tétrahydroisoquinoléine substitués
FR2874011B1 (fr) * 2004-08-03 2007-06-15 Sanofi Synthelabo Derives de sulfonamides, leur preparation et leur application en therapeutique
JP4582722B2 (ja) * 2006-03-15 2010-11-17 アクテリオン ファーマシューティカルズ リミテッド 記憶機能を向上させるテトラヒドロイソキノリン誘導体

Also Published As

Publication number Publication date
CN101400348A (zh) 2009-04-01
CA2644010A1 (fr) 2007-09-20
WO2007105177A1 (fr) 2007-09-20
NO20084253L (no) 2008-10-10
EA200870357A1 (ru) 2009-02-27
EA015256B1 (ru) 2011-06-30
EP1998774A1 (fr) 2008-12-10
UA93903C2 (ru) 2011-03-25
US20090082394A1 (en) 2009-03-26
MA30327B1 (fr) 2009-04-01
MX2008011647A (es) 2008-09-22
JP2009530265A (ja) 2009-08-27
AU2007226203A1 (en) 2007-09-20
BRPI0708913A2 (pt) 2011-06-14
JP2010270127A (ja) 2010-12-02
JP4582722B2 (ja) 2010-11-17
JP2010248237A (ja) 2010-11-04
KR20080103597A (ko) 2008-11-27
KR101065239B1 (ko) 2011-09-16
IL194044A0 (en) 2009-09-22

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)