CR10260A - - Google Patents

Info

Publication number
CR10260A
CR10260A CR10260A CR10260A CR10260A CR 10260 A CR10260 A CR 10260A CR 10260 A CR10260 A CR 10260A CR 10260 A CR10260 A CR 10260A CR 10260 A CR10260 A CR 10260A
Authority
CR
Costa Rica
Application number
CR10260A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of CR10260A publication Critical patent/CR10260A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CR10260A 2006-03-15 2008-08-28 CR10260A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB2006050812 2006-03-15

Publications (1)

Publication Number Publication Date
CR10260A true CR10260A (fr) 2008-10-03

Family

ID=38181192

Family Applications (1)

Application Number Title Priority Date Filing Date
CR10260A CR10260A (fr) 2006-03-15 2008-08-28

Country Status (16)

Country Link
US (1) US20090082394A1 (fr)
EP (1) EP1998774A1 (fr)
JP (3) JP4582722B2 (fr)
KR (1) KR101065239B1 (fr)
CN (1) CN101400348A (fr)
AU (1) AU2007226203A1 (fr)
BR (1) BRPI0708913A2 (fr)
CA (1) CA2644010A1 (fr)
CR (1) CR10260A (fr)
EA (1) EA015256B1 (fr)
IL (1) IL194044A0 (fr)
MA (1) MA30327B1 (fr)
MX (1) MX2008011647A (fr)
NO (1) NO20084253L (fr)
UA (1) UA93903C2 (fr)
WO (1) WO2007105177A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1926109B (zh) 2004-03-01 2011-04-13 埃科特莱茵药品有限公司 经取代的1,2,3,4-四氢异喹啉衍生物
US20090082394A1 (en) * 2006-03-15 2009-03-26 Actelion Pharmaceuticals, Ltd. Tetrahydroisoquinoline Derivatives to Enhance Memory Function
WO2007122591A2 (fr) * 2006-04-26 2007-11-01 Actelion Pharmaceuticals Ltd Nouveaux dérivés de pyrazolo-tétrahydropyridine
CN101568542B (zh) 2006-12-22 2013-03-27 埃科特莱茵药品有限公司 5,6,7,8-四氢-咪唑并[1,5-a]吡嗪衍生物
ES2365444T3 (es) * 2007-04-04 2011-10-05 F. Hoffmann-La Roche Ag Heterociclos como antagonistas de orexina.
PE20091010A1 (es) * 2007-10-10 2009-08-08 Actelion Pharmaceuticals Ltd Derivados de tetrahidroquinolina
US8084464B2 (en) 2007-12-18 2011-12-27 Concert Pharmaceuticals, Inc. Tetrahydroisoquinoline derivatives
ATE528295T1 (de) 2007-12-28 2011-10-15 Actelion Pharmaceuticals Ltd Trisubstituierte 3,4-dihydro-1h-isochinolin- verbindung, verfahren zu ihrer herstellung und ihre anwendung
WO2009156951A2 (fr) 2008-06-25 2009-12-30 Actelion Pharmaceuticals Ltd Composés de 5,6,7,8-tétrahydro-imidazo[1,5-a]pyrazine
WO2010095106A1 (fr) 2009-02-20 2010-08-26 Actelion Pharmaceuticals Ltd Formes solides de chlorhydrate de( 2r)-2-{(is)-6, 7-diméthoxy- 1-[2- (4-trifluorométhyl-phényl)-éthyl]-3, 4-dihydro-1h-isoquinolin-2-yl}-n-méthyl-2-phényl acétamide
WO2012025877A1 (fr) 2010-08-24 2012-03-01 Actelion Pharmaceuticals Ltd Dérivés de proline sulfonamide comme antagonistes des récepteurs de l'orexine
TWI516484B (zh) 2010-09-22 2016-01-11 衛材Ｒ＆Ｄ企管股份有限公司 環丙烷化合物
EP2638008B1 (fr) 2010-11-10 2015-07-01 Actelion Pharmaceuticals Ltd Dérivés de lactame utiles en tant qu'antagonistes du récepteur de l'orexine
WO2012085852A1 (fr) 2010-12-22 2012-06-28 Actelion Pharmaceuticals Ltd 3,8-diaza-bicyclo[4.2.0]oct-8-ylamides
CN103380130B (zh) 2011-02-18 2015-06-17 埃科特莱茵药品有限公司 用作为食欲素拮抗剂的新颖的吡唑和咪唑衍生物
WO2012114252A1 (fr) 2011-02-21 2012-08-30 Actelion Pharmaceuticals Ltd Nouveaux amides d'indole et de pyrrolopyridine
WO2013050938A1 (fr) 2011-10-04 2013-04-11 Actelion Pharmaceuticals Ltd Dérivés de 3,7-diazabicyclo[3.3.1]nonane et de 9-oxa-3,7- diazabicyclo[3.3.1]nonane
CA2846568C (fr) 2011-11-08 2020-01-14 Actelion Pharmaceuticals Ltd Derives de 2-(1,2,3-triazol-2-yl)benzamide et de 3-(1,2,3-triazol-2-yl)picolinamide en tant qu'antagonistes des recepteurs d'orexine
EA029899B1 (ru) 2012-06-04 2018-05-31 Идорсиа Фармасьютиклз Лтд Производные бензимидазол-пролина
MX2015004638A (es) 2012-10-10 2015-07-14 Actelion Pharmaceuticals Ltd Antagonistas de receptores de orexina los cuales son derivados de [orto bi-(hetero-) aril]-[2-meta bi-(hetero-) aril)-pirrolidin-1-il]-metanona.
EP2970241A1 (fr) 2013-03-12 2016-01-20 Actelion Pharmaceuticals Ltd. Dérivés d'amide d'azétidine en tant qu'antagonistes des récepteurs d'oréxine
NZ721438A (en) 2013-12-03 2021-12-24 Idorsia Pharmaceuticals Ltd Crystalline form of (s)-(2-(6-chloro-7-methyl-1h-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1 -yl)(5-methoxy-2-(2h-1,2,3-triazol-2-yl)phenyl)methanone and its use as orexin receptor antagonists
UA119151C2 (uk) 2013-12-03 2019-05-10 Ідорсія Фармасьютікалз Лтд КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА
SI3077391T1 (sl) 2013-12-04 2018-11-30 Idorsia Pharmaceuticals Ltd Uporaba benzimidazol-prolinskih derivatov
SG10202007759RA (en) 2014-10-23 2020-09-29 Eisai R&D Man Co Ltd Compositions and methods for treating insomnia
WO2020007964A1 (fr) 2018-07-05 2020-01-09 Idorsia Pharmaceuticals Ltd Dérivés de 2-(2-azabicyclo [3.1.0] hexan-1-yl)-1h-benzimidazole
WO2020007977A1 (fr) 2018-07-06 2020-01-09 Idorsia Pharmaceuticals Ltd Dérivés de 7-trifluorométhyl-[1,4]diazépane
WO2020099511A1 (fr) 2018-11-14 2020-05-22 Idorsia Pharmaceuticals Ltd Dérivés de benzimidazole-2-méthyl-morpholine
TW202400149A (zh) 2022-05-13 2024-01-01 瑞士商愛杜西亞製藥有限公司 經噻唑并芳基-甲基取代之環狀肼-n-甲醯胺衍生物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703050B1 (fr) * 1993-03-24 1995-04-28 Adir Nouveaux dérivés bicycliques azotés, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
GB9319732D0 (en) * 1993-09-24 1993-11-10 Ucb Sa Use of (s)-alpha-ethyl-2-oxo-l-pyrrolidineacetamide for the treatment of anxiety
JP3942207B2 (ja) * 1995-02-17 2007-07-11 武田薬品工業株式会社 うつ性症状改善剤
JP4009460B2 (ja) * 2000-03-14 2007-11-14 アクテリオン ファマシューティカルズ リミテッド １，２，３，４−テトラヒドロイソキノリン誘導体
US6838465B2 (en) * 2000-05-11 2005-01-04 Banyu Pharmaceutical Co., Ltd. N-acyltetrahydroisoquinoline derivatives
WO2002051232A2 (fr) * 2000-12-27 2002-07-04 Actelion Pharmaceuticals Ltd. Nouvelles benzazepines et derives heterocycliques associes
KR100681585B1 (ko) * 2002-04-26 2007-02-09 에프. 호프만-라 로슈 아게 아이소퀴놀린 유도체
WO2004085403A1 (fr) * 2003-03-26 2004-10-07 Actelion Pharmaceuticals Ltd Derives de tetrahydro-isoquinolyl-acetamide destines a servir d'antagonistes des recepteurs d'orexine
CN1926109B (zh) * 2004-03-01 2011-04-13 埃科特莱茵药品有限公司 经取代的1,2,3,4-四氢异喹啉衍生物
FR2874011B1 (fr) * 2004-08-03 2007-06-15 Sanofi Synthelabo Derives de sulfonamides, leur preparation et leur application en therapeutique
US20090082394A1 (en) * 2006-03-15 2009-03-26 Actelion Pharmaceuticals, Ltd. Tetrahydroisoquinoline Derivatives to Enhance Memory Function

Also Published As

Publication number Publication date
JP4582722B2 (ja) 2010-11-17
JP2010270127A (ja) 2010-12-02
EA015256B1 (ru) 2011-06-30
IL194044A0 (en) 2009-09-22
NO20084253L (no) 2008-10-10
UA93903C2 (ru) 2011-03-25
EA200870357A1 (ru) 2009-02-27
EP1998774A1 (fr) 2008-12-10
CA2644010A1 (fr) 2007-09-20
MA30327B1 (fr) 2009-04-01
WO2007105177A1 (fr) 2007-09-20
JP2009530265A (ja) 2009-08-27
MX2008011647A (es) 2008-09-22
AU2007226203A1 (en) 2007-09-20
BRPI0708913A2 (pt) 2011-06-14
US20090082394A1 (en) 2009-03-26
JP2010248237A (ja) 2010-11-04
KR20080103597A (ko) 2008-11-27
CN101400348A (zh) 2009-04-01
KR101065239B1 (ko) 2011-09-16

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)