CO6541539A2 - Procesos para preparar las formas cristalinas a y b de ilaprazol y proceso para convertir las formas cristalinas - Google Patents
Procesos para preparar las formas cristalinas a y b de ilaprazol y proceso para convertir las formas cristalinasInfo
- Publication number
- CO6541539A2 CO6541539A2 CO12097489A CO12097489A CO6541539A2 CO 6541539 A2 CO6541539 A2 CO 6541539A2 CO 12097489 A CO12097489 A CO 12097489A CO 12097489 A CO12097489 A CO 12097489A CO 6541539 A2 CO6541539 A2 CO 6541539A2
- Authority
- CO
- Colombia
- Prior art keywords
- crystal forms
- crystalline form
- ilaprazole
- preparing
- ilaprazol
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- HRRXCXABAPSOCP-UHFFFAOYSA-N ilaprazole Chemical compound COC1=CC=NC(CS(=O)C=2NC3=CC(=CC=C3N=2)N2C=CC=C2)=C1C HRRXCXABAPSOCP-UHFFFAOYSA-N 0.000 abstract 4
- 229950008491 ilaprazole Drugs 0.000 abstract 4
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 2
- 239000012046 mixed solvent Substances 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020090121209A KR101144600B1 (ko) | 2009-12-08 | 2009-12-08 | 일라프라졸의 결정형 ａ, ｂ의 제조방법 및 이들 결정형의 변환방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6541539A2 true CO6541539A2 (es) | 2012-10-16 |
Family
ID=44146052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO12097489A CO6541539A2 (es) | 2009-12-08 | 2012-06-08 | Procesos para preparar las formas cristalinas a y b de ilaprazol y proceso para convertir las formas cristalinas |
Country Status (7)
| Country | Link |
|---|---|
| KR (1) | KR101144600B1 (instruction) |
| BR (1) | BR112012012212A2 (instruction) |
| CO (1) | CO6541539A2 (instruction) |
| EA (1) | EA019058B1 (instruction) |
| IN (1) | IN2012DN03176A (instruction) |
| UA (1) | UA102787C2 (instruction) |
| WO (1) | WO2011071314A2 (instruction) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103204843B (zh) * | 2012-01-13 | 2014-12-31 | 丽珠医药集团股份有限公司 | 结晶型艾普拉唑钠乙醇化物及其制备方法 |
| CN103204842B (zh) * | 2012-01-13 | 2014-10-15 | 丽珠医药集团股份有限公司 | 结晶型艾普拉唑钠水合物及其制备方法 |
| WO2013114232A1 (en) | 2012-02-02 | 2013-08-08 | Lupin Limited | Process for preparation of crystalline form l of ilaprazole |
| CN102746276B (zh) * | 2012-06-21 | 2014-07-02 | 丽珠医药集团股份有限公司 | 一种艾普拉唑钠晶型及其制备方法 |
| CN102746277B (zh) * | 2012-06-21 | 2014-05-14 | 丽珠医药集团股份有限公司 | 一种结晶形式的艾普拉唑钠及其制备方法 |
| CN102746275B (zh) * | 2012-06-21 | 2014-07-16 | 丽珠医药集团股份有限公司 | 结晶型艾普拉唑钠及其制备方法 |
| CN105461692A (zh) * | 2014-09-04 | 2016-04-06 | 江苏奥赛康药业股份有限公司 | 艾普拉唑钠化合物及其药物组合物 |
| CN115403560B (zh) * | 2017-11-06 | 2024-09-03 | 丽珠医药集团股份有限公司 | 一种艾普拉唑镁晶型及其制备方法 |
| KR102027388B1 (ko) * | 2017-11-15 | 2019-10-01 | 주식회사 다산제약 | 고순도 일라프라졸 결정형 b의 제조방법 |
| CN111187255B (zh) * | 2020-01-13 | 2021-07-20 | 丽珠医药集团股份有限公司 | 右旋艾普拉唑钾盐的制备方法和右旋艾普拉唑的制备方法 |
| KR20220065235A (ko) | 2020-11-13 | 2022-05-20 | 주식회사 파마코스텍 | 일라프라졸 혼형 결정의 신규한 제조방법 |
| KR102250509B1 (ko) * | 2020-12-09 | 2021-05-11 | 유니셀랩 주식회사 | 새로운 일라프라졸/자일리톨 공결정 |
| KR20210019469A (ko) | 2021-02-02 | 2021-02-22 | 주식회사 파마코스텍 | 일라프라졸 나트륨 결정형 및 신규한 제조방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080200515A1 (en) * | 2006-12-29 | 2008-08-21 | Tap Pharmaceutical Products Inc. | Solid state forms of enantiopure ilaprazole |
| WO2008083341A1 (en) * | 2006-12-29 | 2008-07-10 | Il Yang Pharmaceutical Company, Ltd. | Crystalline forms of solvated ilaprazole |
-
2009
- 2009-12-08 KR KR1020090121209A patent/KR101144600B1/ko active Active
-
2010
- 2010-12-08 UA UAA201207006A patent/UA102787C2/ru unknown
- 2010-12-08 BR BR112012012212A patent/BR112012012212A2/pt not_active Application Discontinuation
- 2010-12-08 EA EA201200716A patent/EA019058B1/ru not_active IP Right Cessation
- 2010-12-08 WO PCT/KR2010/008767 patent/WO2011071314A2/en active Application Filing
- 2010-12-08 IN IN3176DEN2012 patent/IN2012DN03176A/en unknown
-
2012
- 2012-06-08 CO CO12097489A patent/CO6541539A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR101144600B1 (ko) | 2012-05-16 |
| EA019058B1 (ru) | 2013-12-30 |
| EA201200716A1 (ru) | 2012-10-30 |
| KR20110064545A (ko) | 2011-06-15 |
| UA102787C2 (ru) | 2013-08-12 |
| BR112012012212A2 (pt) | 2015-09-08 |
| WO2011071314A3 (en) | 2011-11-10 |
| WO2011071314A2 (en) | 2011-06-16 |
| IN2012DN03176A (instruction) | 2015-09-25 |
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