CO5690649A2 - Eliminacion de agregados de alto peso molecular utilizando cromatografia de hidroxiapatita - Google Patents

Eliminacion de agregados de alto peso molecular utilizando cromatografia de hidroxiapatita

Info

Publication number
CO5690649A2
CO5690649A2 CO06048228A CO06048228A CO5690649A2 CO 5690649 A2 CO5690649 A2 CO 5690649A2 CO 06048228 A CO06048228 A CO 06048228A CO 06048228 A CO06048228 A CO 06048228A CO 5690649 A2 CO5690649 A2 CO 5690649A2
Authority
CO
Colombia
Prior art keywords
molecular weight
high molecular
hydroxiapatita
elimination
chromatography
Prior art date
Application number
CO06048228A
Other languages
English (en)
Spanish (es)
Inventor
Shujun Sun
Christopher Gallo
Brian Kelley
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of CO5690649A2 publication Critical patent/CO5690649A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3847—Multimodal interactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/04—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium
    • B01J20/048—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising compounds of alkali metals, alkaline earth metals or magnesium containing phosphorus, e.g. phosphates, apatites, hydroxyapatites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CO06048228A 2003-10-27 2006-05-19 Eliminacion de agregados de alto peso molecular utilizando cromatografia de hidroxiapatita CO5690649A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51401803P 2003-10-27 2003-10-27
US52333503P 2003-11-20 2003-11-20

Publications (1)

Publication Number Publication Date
CO5690649A2 true CO5690649A2 (es) 2006-10-31

Family

ID=34576743

Family Applications (1)

Application Number Title Priority Date Filing Date
CO06048228A CO5690649A2 (es) 2003-10-27 2006-05-19 Eliminacion de agregados de alto peso molecular utilizando cromatografia de hidroxiapatita

Country Status (19)

Country Link
US (2) US9469672B2 (https=)
EP (2) EP2336172B1 (https=)
JP (2) JP5004586B2 (https=)
KR (2) KR101221862B1 (https=)
CN (2) CN102276717B (https=)
AU (1) AU2004286938B2 (https=)
BR (2) BRPI0415887B1 (https=)
CA (1) CA2543193C (https=)
CO (1) CO5690649A2 (https=)
DK (2) DK2336172T3 (https=)
EC (1) ECSP066583A (https=)
ES (2) ES2418830T3 (https=)
IL (1) IL175229A (https=)
MX (1) MXPA06004472A (https=)
NZ (1) NZ547315A (https=)
PL (2) PL1678208T3 (https=)
PT (2) PT1678208E (https=)
RU (2) RU2409591C2 (https=)
WO (1) WO2005044856A2 (https=)

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PL1678208T3 (pl) 2013-09-30
WO2005044856A2 (en) 2005-05-19
RU2573910C2 (ru) 2016-01-27
DK2336172T3 (en) 2015-01-26
ES2530446T3 (es) 2015-03-02
CA2543193A1 (en) 2005-05-19
CN102276717B (zh) 2015-09-09
MXPA06004472A (es) 2006-06-20
IL175229A (en) 2013-08-29
KR101221862B1 (ko) 2013-01-14
RU2010139827A (ru) 2012-03-27
PL2336172T3 (pl) 2015-04-30
BRPI0415887B1 (pt) 2021-01-26
IL175229A0 (en) 2006-09-05
RU2409591C2 (ru) 2011-01-20
KR20120003027A (ko) 2012-01-09
ES2418830T3 (es) 2013-08-16
AU2004286938B2 (en) 2011-06-30
EP1678208A2 (en) 2006-07-12
US9469672B2 (en) 2016-10-18
KR20060120163A (ko) 2006-11-24
PT2336172E (pt) 2015-02-20
JP5004586B2 (ja) 2012-08-22
BR122020007658B1 (pt) 2021-07-27
BRPI0415887A (pt) 2007-01-09
CN1898266B (zh) 2011-09-21
EP2336172A1 (en) 2011-06-22
CN102276717A (zh) 2011-12-14
JP2012111769A (ja) 2012-06-14
AU2004286938A1 (en) 2005-05-19
WO2005044856A3 (en) 2005-06-23
DK1678208T3 (da) 2013-07-08
CA2543193C (en) 2015-08-11
RU2006113695A (ru) 2007-12-10
EP2336172B1 (en) 2014-12-10
JP5490156B2 (ja) 2014-05-14
US9822143B2 (en) 2017-11-21
EP1678208B1 (en) 2013-05-15
KR101321876B1 (ko) 2013-10-28
JP2007532477A (ja) 2007-11-15
US20050107594A1 (en) 2005-05-19
CN1898266A (zh) 2007-01-17
PT1678208E (pt) 2013-07-10
ECSP066583A (es) 2006-10-17
US20130197198A1 (en) 2013-08-01
NZ547315A (https=) 2008-07-31

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