CO5160265A1 - Esteres aminoacidos de ribavirina y composiciones farmaceuticas que los contienen . - Google Patents

Esteres aminoacidos de ribavirina y composiciones farmaceuticas que los contienen .

Info

Publication number
CO5160265A1
CO5160265A1 CO99065259A CO99065259A CO5160265A1 CO 5160265 A1 CO5160265 A1 CO 5160265A1 CO 99065259 A CO99065259 A CO 99065259A CO 99065259 A CO99065259 A CO 99065259A CO 5160265 A1 CO5160265 A1 CO 5160265A1
Authority
CO
Colombia
Prior art keywords
aminoacidos
ribavirina
esteres
contain
pharmaceutical compositions
Prior art date
Application number
CO99065259A
Other languages
English (en)
Inventor
K Ganguly Ashit
Mccormick Jinping
Raymond G Lovey
Frank Bennett
K Saksena Anil
M Girijavallab Viyyoor
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CO5160265A1 publication Critical patent/CO5160265A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un método para tratar un paciente que padece de una infección por hepatitis C crónica, a los efectos de erradicar el HCV - RNA detectable, que comprende una terapia combinatoria, la cual emplea una cantidad terapéuticamente efectiva de un derivado de ribavirina de la fórmula I y una cantidad terapéuticamente efectiva de interferón alfa, durante un lapso que varía entre 20 y 80 semanas.
CO99065259A 1998-10-16 1999-10-14 Esteres aminoacidos de ribavirina y composiciones farmaceuticas que los contienen . CO5160265A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17405998A 1998-10-16 1998-10-16
US09/348,534 US6277830B1 (en) 1998-10-16 1999-07-07 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon

Publications (1)

Publication Number Publication Date
CO5160265A1 true CO5160265A1 (es) 2002-05-30

Family

ID=22634639

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99065259A CO5160265A1 (es) 1998-10-16 1999-10-14 Esteres aminoacidos de ribavirina y composiciones farmaceuticas que los contienen .

Country Status (9)

Country Link
US (1) US6277830B1 (es)
EP (1) EP1121370A1 (es)
KR (1) KR20010080098A (es)
AR (1) AR021226A1 (es)
AU (1) AU1197600A (es)
CO (1) CO5160265A1 (es)
PE (1) PE20001109A1 (es)
WO (1) WO2000023455A1 (es)
ZA (1) ZA200102917B (es)

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Also Published As

Publication number Publication date
ZA200102917B (en) 2002-07-09
WO2000023455A1 (en) 2000-04-27
AU1197600A (en) 2000-05-08
WO2000023455A9 (en) 2000-08-24
AR021226A1 (es) 2002-07-03
KR20010080098A (ko) 2001-08-22
US6277830B1 (en) 2001-08-21
PE20001109A1 (es) 2000-10-28
EP1121370A1 (en) 2001-08-08

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