CO5140125A1 - Metodo para la preparacion de eteres de arilo - Google Patents
Metodo para la preparacion de eteres de ariloInfo
- Publication number
- CO5140125A1 CO5140125A1 CO99081078A CO99081078A CO5140125A1 CO 5140125 A1 CO5140125 A1 CO 5140125A1 CO 99081078 A CO99081078 A CO 99081078A CO 99081078 A CO99081078 A CO 99081078A CO 5140125 A1 CO5140125 A1 CO 5140125A1
- Authority
- CO
- Colombia
- Prior art keywords
- optionally substituted
- jpeg
- formula
- give
- groups
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 150000002009 diols Chemical class 0.000 abstract 2
- 150000002118 epoxides Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- OOCCDEMITAIZTP-UHFFFAOYSA-N cinnamyl alcohol Chemical class OCC=CC1=CC=CC=C1 OOCCDEMITAIZTP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000001181 organosilyl group Chemical group [SiH3]* 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000002989 phenols Chemical class 0.000 abstract 1
- 238000006884 silylation reaction Methods 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/03—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
- C07D301/14—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic peracids, or salts, anhydrides or esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11409298P | 1998-12-29 | 1998-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5140125A1 true CO5140125A1 (es) | 2002-03-22 |
Family
ID=22353332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO99081078A CO5140125A1 (es) | 1998-12-29 | 1999-12-28 | Metodo para la preparacion de eteres de arilo |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6376711B1 (enExample) |
| EP (2) | EP1140788B1 (enExample) |
| JP (1) | JP2002533430A (enExample) |
| KR (2) | KR100616386B1 (enExample) |
| CN (3) | CN1308332C (enExample) |
| AT (2) | ATE260238T1 (enExample) |
| AU (1) | AU764492B2 (enExample) |
| BR (1) | BR9916615A (enExample) |
| CA (1) | CA2349619A1 (enExample) |
| CO (1) | CO5140125A1 (enExample) |
| DE (2) | DE69915110T2 (enExample) |
| DK (1) | DK1140788T3 (enExample) |
| ES (1) | ES2214060T3 (enExample) |
| HK (1) | HK1041688B (enExample) |
| HU (1) | HUP0202144A3 (enExample) |
| IL (2) | IL144012A (enExample) |
| NZ (1) | NZ511452A (enExample) |
| PE (1) | PE20001366A1 (enExample) |
| PT (1) | PT1140788E (enExample) |
| SI (1) | SI1140788T1 (enExample) |
| TR (1) | TR200101885T2 (enExample) |
| TW (1) | TWI238155B (enExample) |
| WO (1) | WO2000039072A1 (enExample) |
| ZA (1) | ZA200103532B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2796069B3 (fr) | 1999-07-09 | 2001-08-24 | Sanofi Synthelabo | Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes |
| AR030284A1 (es) * | 2000-06-08 | 2003-08-20 | Merck & Co Inc | Proceso para la sintesis de (2r, 2-alfa-r,3a) -2-[1-(3,5-bis(trifluorometil) fenil) etoxi]-3-(4-fluorofenil)-1,4-oxazina; dicho compuesto y sus formas polimorficas |
| WO2005082869A1 (en) * | 2004-02-20 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Method for the preparation of aryl ethers |
| BRPI0507917A (pt) * | 2004-02-20 | 2007-07-10 | Pharmacia & Upjohn Co Llc | método para preparação de éteres de arila |
| WO2005095435A1 (ja) * | 2004-03-31 | 2005-10-13 | Kuraray Co., Ltd. | プレグナン誘導体の製造方法 |
| GB0409744D0 (en) * | 2004-04-30 | 2004-06-09 | Pfizer Ltd | Novel compounds |
| CA2564994A1 (en) | 2004-04-30 | 2005-11-10 | Warner-Lambert Company Llc | Substituted morpholine compounds for the treatment of central nervous system disorders |
| GEP20125425B (en) | 2006-10-18 | 2012-03-26 | Pfizer Prod Inc | Biaryl ether urea compounds |
| US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
| CN103804316A (zh) * | 2012-11-13 | 2014-05-21 | 天津药物研究院 | 一种（2RS,3RS）-6-[a-（2-乙氧基苯氧基）苄基]吗啉-3-酮（Ⅰ）的制备方法 |
| CN104557936A (zh) * | 2015-01-15 | 2015-04-29 | 河南科技学院 | 一种新型手性非环嘌呤核苷类似物的合成方法 |
| US20190381056A1 (en) | 2018-06-17 | 2019-12-19 | Axsome Therapeutics, Inc. | Compositions for delivery of reboxetine |
| US20200147093A1 (en) | 2018-10-15 | 2020-05-14 | Axsome Therapeutics, Inc. | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
| US11020402B2 (en) | 2018-10-15 | 2021-06-01 | Axsome Therapeutics, Inc. | Use of reboxetine to treat narcolepsy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2785185A (en) * | 1952-08-07 | 1957-03-12 | Union Carbide & Carbon Corp | Process for making oxirane compounds from olefins and aldehyde monoperacylates |
| GB1053972A (enExample) * | 1962-08-30 | 1967-01-04 | ||
| IL56369A (en) * | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
| GB8419683D0 (en) * | 1984-08-02 | 1984-09-05 | Erba Farmitalia | 3-substituted derivatives of 1-amino-2-hydroxy-propane |
-
1999
- 1999-12-23 HU HU0202144A patent/HUP0202144A3/hu unknown
- 1999-12-23 JP JP2000590985A patent/JP2002533430A/ja active Pending
- 1999-12-23 HK HK02103399.9A patent/HK1041688B/zh not_active IP Right Cessation
- 1999-12-23 IL IL14401299A patent/IL144012A/xx not_active IP Right Cessation
- 1999-12-23 BR BR9916615-1A patent/BR9916615A/pt not_active Application Discontinuation
- 1999-12-23 WO PCT/US1999/030748 patent/WO2000039072A1/en not_active Ceased
- 1999-12-23 NZ NZ511452A patent/NZ511452A/xx unknown
- 1999-12-23 DK DK99967557T patent/DK1140788T3/da active
- 1999-12-23 SI SI9930559T patent/SI1140788T1/xx unknown
- 1999-12-23 AU AU23819/00A patent/AU764492B2/en not_active Ceased
- 1999-12-23 AT AT99967557T patent/ATE260238T1/de not_active IP Right Cessation
- 1999-12-23 AT AT03002146T patent/ATE430144T1/de not_active IP Right Cessation
- 1999-12-23 CN CNB998153028A patent/CN1308332C/zh not_active Expired - Fee Related
- 1999-12-23 KR KR1020017008269A patent/KR100616386B1/ko not_active Expired - Fee Related
- 1999-12-23 DE DE69915110T patent/DE69915110T2/de not_active Expired - Fee Related
- 1999-12-23 DE DE69940833T patent/DE69940833D1/de not_active Expired - Fee Related
- 1999-12-23 CN CNB2004100869263A patent/CN100340552C/zh not_active Expired - Fee Related
- 1999-12-23 KR KR1020067014909A patent/KR100616029B1/ko not_active Expired - Fee Related
- 1999-12-23 EP EP99967557A patent/EP1140788B1/en not_active Expired - Lifetime
- 1999-12-23 IL IL16184099A patent/IL161840A0/xx not_active IP Right Cessation
- 1999-12-23 ES ES99967557T patent/ES2214060T3/es not_active Expired - Lifetime
- 1999-12-23 US US09/469,429 patent/US6376711B1/en not_active Expired - Fee Related
- 1999-12-23 EP EP03002146A patent/EP1308443B1/en not_active Expired - Lifetime
- 1999-12-23 CN CNB2004100323697A patent/CN1249038C/zh not_active Expired - Fee Related
- 1999-12-23 TR TR2001/01885T patent/TR200101885T2/xx unknown
- 1999-12-23 PT PT99967557T patent/PT1140788E/pt unknown
- 1999-12-23 CA CA002349619A patent/CA2349619A1/en not_active Abandoned
- 1999-12-24 TW TW088122940A patent/TWI238155B/zh not_active IP Right Cessation
- 1999-12-28 CO CO99081078A patent/CO5140125A1/es unknown
- 1999-12-28 PE PE1999001328A patent/PE20001366A1/es not_active Application Discontinuation
-
2001
- 2001-05-02 ZA ZA200103532A patent/ZA200103532B/en unknown
Also Published As
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