BR9916615A - Método para a preparação de éteres de arila - Google Patents
Método para a preparação de éteres de arilaInfo
- Publication number
- BR9916615A BR9916615A BR9916615-1A BR9916615A BR9916615A BR 9916615 A BR9916615 A BR 9916615A BR 9916615 A BR9916615 A BR 9916615A BR 9916615 A BR9916615 A BR 9916615A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- aryl ethers
- compound
- formula
- ethers
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 150000008378 aryl ethers Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D301/00—Preparation of oxiranes
- C07D301/02—Synthesis of the oxirane ring
- C07D301/03—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds
- C07D301/14—Synthesis of the oxirane ring by oxidation of unsaturated compounds, or of mixtures of unsaturated and saturated compounds with organic peracids, or salts, anhydrides or esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11409298P | 1998-12-29 | 1998-12-29 | |
| PCT/US1999/030748 WO2000039072A1 (en) | 1998-12-29 | 1999-12-23 | Method for the preparation of aryl ethers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9916615A true BR9916615A (pt) | 2001-10-23 |
Family
ID=22353332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9916615-1A BR9916615A (pt) | 1998-12-29 | 1999-12-23 | Método para a preparação de éteres de arila |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6376711B1 (enExample) |
| EP (2) | EP1140788B1 (enExample) |
| JP (1) | JP2002533430A (enExample) |
| KR (2) | KR100616386B1 (enExample) |
| CN (3) | CN1308332C (enExample) |
| AT (2) | ATE260238T1 (enExample) |
| AU (1) | AU764492B2 (enExample) |
| BR (1) | BR9916615A (enExample) |
| CA (1) | CA2349619A1 (enExample) |
| CO (1) | CO5140125A1 (enExample) |
| DE (2) | DE69915110T2 (enExample) |
| DK (1) | DK1140788T3 (enExample) |
| ES (1) | ES2214060T3 (enExample) |
| HK (1) | HK1041688B (enExample) |
| HU (1) | HUP0202144A3 (enExample) |
| IL (2) | IL144012A (enExample) |
| NZ (1) | NZ511452A (enExample) |
| PE (1) | PE20001366A1 (enExample) |
| PT (1) | PT1140788E (enExample) |
| SI (1) | SI1140788T1 (enExample) |
| TR (1) | TR200101885T2 (enExample) |
| TW (1) | TWI238155B (enExample) |
| WO (1) | WO2000039072A1 (enExample) |
| ZA (1) | ZA200103532B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2796069B3 (fr) | 1999-07-09 | 2001-08-24 | Sanofi Synthelabo | Nouveaux procedes de preparation de derives de 2-(2- arylmorpholin-2-yl)ethanol substitues, enantiomeriquement purs, et composes intermediaires utiles dans ces procedes |
| AR030284A1 (es) * | 2000-06-08 | 2003-08-20 | Merck & Co Inc | Proceso para la sintesis de (2r, 2-alfa-r,3a) -2-[1-(3,5-bis(trifluorometil) fenil) etoxi]-3-(4-fluorofenil)-1,4-oxazina; dicho compuesto y sus formas polimorficas |
| WO2005082869A1 (en) * | 2004-02-20 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Method for the preparation of aryl ethers |
| BRPI0507917A (pt) * | 2004-02-20 | 2007-07-10 | Pharmacia & Upjohn Co Llc | método para preparação de éteres de arila |
| WO2005095435A1 (ja) * | 2004-03-31 | 2005-10-13 | Kuraray Co., Ltd. | プレグナン誘導体の製造方法 |
| GB0409744D0 (en) * | 2004-04-30 | 2004-06-09 | Pfizer Ltd | Novel compounds |
| CA2564994A1 (en) | 2004-04-30 | 2005-11-10 | Warner-Lambert Company Llc | Substituted morpholine compounds for the treatment of central nervous system disorders |
| GEP20125425B (en) | 2006-10-18 | 2012-03-26 | Pfizer Prod Inc | Biaryl ether urea compounds |
| US20100069389A1 (en) * | 2008-09-06 | 2010-03-18 | Bionevia Pharmaceuticals, Inc. | Novel forms of reboxetine |
| CN103804316A (zh) * | 2012-11-13 | 2014-05-21 | 天津药物研究院 | 一种（2RS,3RS）-6-[a-（2-乙氧基苯氧基）苄基]吗啉-3-酮（Ⅰ）的制备方法 |
| CN104557936A (zh) * | 2015-01-15 | 2015-04-29 | 河南科技学院 | 一种新型手性非环嘌呤核苷类似物的合成方法 |
| US20190381056A1 (en) | 2018-06-17 | 2019-12-19 | Axsome Therapeutics, Inc. | Compositions for delivery of reboxetine |
| US20200147093A1 (en) | 2018-10-15 | 2020-05-14 | Axsome Therapeutics, Inc. | Use of esreboxetine to treat nervous system disorders such as fibromyalgia |
| US11020402B2 (en) | 2018-10-15 | 2021-06-01 | Axsome Therapeutics, Inc. | Use of reboxetine to treat narcolepsy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2785185A (en) * | 1952-08-07 | 1957-03-12 | Union Carbide & Carbon Corp | Process for making oxirane compounds from olefins and aldehyde monoperacylates |
| GB1053972A (enExample) * | 1962-08-30 | 1967-01-04 | ||
| IL56369A (en) * | 1978-01-20 | 1984-05-31 | Erba Farmitalia | Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them |
| GB8419683D0 (en) * | 1984-08-02 | 1984-09-05 | Erba Farmitalia | 3-substituted derivatives of 1-amino-2-hydroxy-propane |
-
1999
- 1999-12-23 HU HU0202144A patent/HUP0202144A3/hu unknown
- 1999-12-23 JP JP2000590985A patent/JP2002533430A/ja active Pending
- 1999-12-23 HK HK02103399.9A patent/HK1041688B/zh not_active IP Right Cessation
- 1999-12-23 IL IL14401299A patent/IL144012A/xx not_active IP Right Cessation
- 1999-12-23 BR BR9916615-1A patent/BR9916615A/pt not_active Application Discontinuation
- 1999-12-23 WO PCT/US1999/030748 patent/WO2000039072A1/en not_active Ceased
- 1999-12-23 NZ NZ511452A patent/NZ511452A/xx unknown
- 1999-12-23 DK DK99967557T patent/DK1140788T3/da active
- 1999-12-23 SI SI9930559T patent/SI1140788T1/xx unknown
- 1999-12-23 AU AU23819/00A patent/AU764492B2/en not_active Ceased
- 1999-12-23 AT AT99967557T patent/ATE260238T1/de not_active IP Right Cessation
- 1999-12-23 AT AT03002146T patent/ATE430144T1/de not_active IP Right Cessation
- 1999-12-23 CN CNB998153028A patent/CN1308332C/zh not_active Expired - Fee Related
- 1999-12-23 KR KR1020017008269A patent/KR100616386B1/ko not_active Expired - Fee Related
- 1999-12-23 DE DE69915110T patent/DE69915110T2/de not_active Expired - Fee Related
- 1999-12-23 DE DE69940833T patent/DE69940833D1/de not_active Expired - Fee Related
- 1999-12-23 CN CNB2004100869263A patent/CN100340552C/zh not_active Expired - Fee Related
- 1999-12-23 KR KR1020067014909A patent/KR100616029B1/ko not_active Expired - Fee Related
- 1999-12-23 EP EP99967557A patent/EP1140788B1/en not_active Expired - Lifetime
- 1999-12-23 IL IL16184099A patent/IL161840A0/xx not_active IP Right Cessation
- 1999-12-23 ES ES99967557T patent/ES2214060T3/es not_active Expired - Lifetime
- 1999-12-23 US US09/469,429 patent/US6376711B1/en not_active Expired - Fee Related
- 1999-12-23 EP EP03002146A patent/EP1308443B1/en not_active Expired - Lifetime
- 1999-12-23 CN CNB2004100323697A patent/CN1249038C/zh not_active Expired - Fee Related
- 1999-12-23 TR TR2001/01885T patent/TR200101885T2/xx unknown
- 1999-12-23 PT PT99967557T patent/PT1140788E/pt unknown
- 1999-12-23 CA CA002349619A patent/CA2349619A1/en not_active Abandoned
- 1999-12-24 TW TW088122940A patent/TWI238155B/zh not_active IP Right Cessation
- 1999-12-28 CO CO99081078A patent/CO5140125A1/es unknown
- 1999-12-28 PE PE1999001328A patent/PE20001366A1/es not_active Application Discontinuation
-
2001
- 2001-05-02 ZA ZA200103532A patent/ZA200103532B/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM ARTIGOS 8O E 13 DA LPI. |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |