CO4520233A1 - Procedimiento para el diagnostico y la terapia de carcinomas del epitelio plano - Google Patents

Procedimiento para el diagnostico y la terapia de carcinomas del epitelio plano

Info

Publication number
CO4520233A1
CO4520233A1 CO96063967A CO96063967A CO4520233A1 CO 4520233 A1 CO4520233 A1 CO 4520233A1 CO 96063967 A CO96063967 A CO 96063967A CO 96063967 A CO96063967 A CO 96063967A CO 4520233 A1 CO4520233 A1 CO 4520233A1
Authority
CO
Colombia
Prior art keywords
procedure
diagnosis
carcinomas
therapy
flat
Prior art date
Application number
CO96063967A
Other languages
English (en)
Spanish (es)
Inventor
Karl Herinz Heider
Adolf Gunther
Elinborg Ostermann
Antonius Dol Paul Erik Patzelt
Marlies Sproll
Original Assignee
Boehringer Ingelheim Pharma
Karlsruhe Forschzent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19545472A external-priority patent/DE19545472A1/de
Application filed by Boehringer Ingelheim Pharma, Karlsruhe Forschzent filed Critical Boehringer Ingelheim Pharma
Publication of CO4520233A1 publication Critical patent/CO4520233A1/es

Links

Classifications

    • G01N33/575
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70585CD44
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CO96063967A 1995-12-06 1996-12-05 Procedimiento para el diagnostico y la terapia de carcinomas del epitelio plano CO4520233A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19545472A DE19545472A1 (de) 1995-12-06 1995-12-06 Verfahren zur Diagnose und Therapie von Plattenepithelkarzinomen
DE19615074 1996-04-17

Publications (1)

Publication Number Publication Date
CO4520233A1 true CO4520233A1 (es) 1997-10-15

Family

ID=26020988

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96063967A CO4520233A1 (es) 1995-12-06 1996-12-05 Procedimiento para el diagnostico y la terapia de carcinomas del epitelio plano

Country Status (25)

Country Link
EP (1) EP0865609B1 (enExample)
JP (1) JP2000502067A (enExample)
KR (1) KR100473824B1 (enExample)
CN (1) CN1151377C (enExample)
AR (1) AR004360A1 (enExample)
AT (1) ATE235056T1 (enExample)
AU (1) AU726704B2 (enExample)
BG (1) BG62985B1 (enExample)
BR (1) BR9611901A (enExample)
CA (1) CA2239709A1 (enExample)
CO (1) CO4520233A1 (enExample)
CZ (1) CZ174198A3 (enExample)
DE (1) DE59610248D1 (enExample)
DK (1) DK0865609T3 (enExample)
EE (1) EE03783B1 (enExample)
ES (1) ES2190484T3 (enExample)
MX (1) MX9804459A (enExample)
NO (1) NO319903B1 (enExample)
NZ (1) NZ324314A (enExample)
PL (1) PL184521B1 (enExample)
PT (1) PT865609E (enExample)
SK (1) SK284378B6 (enExample)
TR (1) TR199801027T2 (enExample)
UY (1) UY24389A1 (enExample)
WO (1) WO1997021104A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7947496B2 (en) * 1999-10-08 2011-05-24 Hoffmann-La Roche Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US7189397B2 (en) * 1999-10-08 2007-03-13 Arius Research Inc. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20050100542A1 (en) * 1999-10-08 2005-05-12 Young David S. Cytotoxicity mediation of cells evidencing surface expression of CD44
US20030103985A1 (en) 2001-05-18 2003-06-05 Boehringer Ingelheim International Gmbh Cytotoxic CD44 antibody immunoconjugates
EP1258255A1 (en) * 2001-05-18 2002-11-20 Boehringer Ingelheim International GmbH Conjugates of an antibody to CD44 and a maytansinoid
CN1541226A (zh) * 2001-05-18 2004-10-27 ���ָ��Ӣ��ķ�������Ϲ�˾ CD44v6特异性的抗体
US6972324B2 (en) 2001-05-18 2005-12-06 Boehringer Ingelheim Pharmaceuticals, Inc. Antibodies specific for CD44v6
EP1391213A1 (en) * 2002-08-21 2004-02-25 Boehringer Ingelheim International GmbH Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
EP1417974A1 (en) * 2002-11-08 2004-05-12 Boehringer Ingelheim International GmbH Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and radiotherapy
JP5763105B2 (ja) * 2010-02-04 2015-08-12 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 頭頸部扁平上皮癌の治療に使用されるcd44に対するモノクローナル抗体
US9218450B2 (en) 2012-11-29 2015-12-22 Roche Molecular Systems, Inc. Accurate and fast mapping of reads to genome
EP3755717A4 (en) * 2018-02-22 2022-01-26 Multitude Inc. THERAPEUTIC ANTIBODY AND USES THEREOF
IL317000A (en) 2022-05-25 2025-01-01 Akiram Therapeutics Ab Antibodies against CD44V6 and their use in the treatment of cancers that overexpress CD44V6

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69406664T2 (de) * 1993-06-18 1998-06-04 Biotie Therapies Oy Zusammensetzungen und diagnostische verfahren unter verwendung von monoklonalen antikoerpern gegen cd44v6
WO1995000851A1 (de) * 1993-06-22 1995-01-05 Boehringer Ingelheim International Gmbh Verfahren zur diagnose und analyse von tumoren
DE4326573A1 (de) * 1993-08-07 1995-02-23 Boehringer Ingelheim Int Durch Exon v5 des CD44-Gens kodierte Polypeptide als Targets für Immuntherapie und Immunszintigraphie von Tumoren
UA58482C2 (uk) * 1994-06-08 2003-08-15 Бьорінгер Інгельхайм Інтернаціональ Гмбх Моноклональне антитіло vff-18 проти сd44v6 і його фрагменти

Also Published As

Publication number Publication date
NO319903B1 (no) 2005-09-26
KR19990071952A (ko) 1999-09-27
MX9804459A (es) 1998-09-30
JP2000502067A (ja) 2000-02-22
EE03783B1 (et) 2002-06-17
CZ174198A3 (cs) 1999-02-17
EE9800164A (et) 1998-12-15
DE59610248D1 (de) 2003-04-24
UY24389A1 (es) 2001-10-25
AR004360A1 (es) 1998-11-04
BR9611901A (pt) 1999-03-02
CA2239709A1 (en) 1997-06-12
KR100473824B1 (ko) 2005-09-30
SK284378B6 (sk) 2005-02-04
NO982588D0 (no) 1998-06-05
PL327066A1 (en) 1998-11-23
ATE235056T1 (de) 2003-04-15
CN1151377C (zh) 2004-05-26
NZ324314A (en) 2000-02-28
HK1011560A1 (en) 1999-07-16
EP0865609A1 (de) 1998-09-23
DK0865609T3 (da) 2003-06-23
AU1177397A (en) 1997-06-27
BG62985B1 (bg) 2000-12-29
AU726704B2 (en) 2000-11-16
PT865609E (pt) 2003-08-29
NO982588L (no) 1998-08-05
ES2190484T3 (es) 2003-08-01
CN1207811A (zh) 1999-02-10
SK73698A3 (en) 1999-01-11
BG102513A (en) 1999-02-26
TR199801027T2 (xx) 1998-10-21
WO1997021104A1 (de) 1997-06-12
PL184521B1 (pl) 2002-11-29
EP0865609B1 (de) 2003-03-19

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