CO2019007776A2 - Composiciones y métodos para tratar la deficiencia de alfa-1 antitripsina - Google Patents

Composiciones y métodos para tratar la deficiencia de alfa-1 antitripsina

Info

Publication number
CO2019007776A2
CO2019007776A2 CONC2019/0007776A CO2019007776A CO2019007776A2 CO 2019007776 A2 CO2019007776 A2 CO 2019007776A2 CO 2019007776 A CO2019007776 A CO 2019007776A CO 2019007776 A2 CO2019007776 A2 CO 2019007776A2
Authority
CO
Colombia
Prior art keywords
methods
compositions
antitrypsin deficiency
treating alpha
antitrypsin
Prior art date
Application number
CONC2019/0007776A
Other languages
English (en)
Spanish (es)
Inventor
Walter Strapps
Shobu Odate
Reynald Michael Lescarbeau
Original Assignee
Intellia Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intellia Therapeutics Inc filed Critical Intellia Therapeutics Inc
Publication of CO2019007776A2 publication Critical patent/CO2019007776A2/es

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C12N9/14—Hydrolases (3)
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    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N2310/00—Structure or type of the nucleic acid
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CONC2019/0007776A 2016-12-22 2019-07-19 Composiciones y métodos para tratar la deficiencia de alfa-1 antitripsina CO2019007776A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662438219P 2016-12-22 2016-12-22
PCT/US2017/067800 WO2018119182A1 (en) 2016-12-22 2017-12-21 Compositions and methods for treating alpha-1 antitrypsin deficiency

Publications (1)

Publication Number Publication Date
CO2019007776A2 true CO2019007776A2 (es) 2019-10-09

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CONC2019/0007776A CO2019007776A2 (es) 2016-12-22 2019-07-19 Composiciones y métodos para tratar la deficiencia de alfa-1 antitripsina

Country Status (19)

Country Link
US (2) US11549107B2 (https=)
EP (1) EP3559232A1 (https=)
JP (2) JP7383478B2 (https=)
KR (1) KR102551664B1 (https=)
CN (2) CN110382697B (https=)
AU (2) AU2017379073B2 (https=)
BR (1) BR112019012825A2 (https=)
CA (1) CA3047415A1 (https=)
CO (1) CO2019007776A2 (https=)
EA (1) EA201991455A1 (https=)
IL (1) IL267448B2 (https=)
MX (2) MX2019007594A (https=)
MY (1) MY204487A (https=)
PH (1) PH12019501457A1 (https=)
SA (1) SA519402192B1 (https=)
SG (1) SG10202106412RA (https=)
TW (2) TWI851534B (https=)
WO (1) WO2018119182A1 (https=)
ZA (1) ZA202007632B (https=)

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CN110382697B (zh) 2023-12-29
KR102551664B1 (ko) 2023-07-05
IL267448B2 (en) 2025-09-01
ZA202007632B (en) 2023-03-29
CA3047415A1 (en) 2018-06-28
CN117737062A (zh) 2024-03-22
CN110382697A (zh) 2019-10-25
EP3559232A1 (en) 2019-10-30
TW201833331A (zh) 2018-09-16
WO2018119182A1 (en) 2018-06-28
US11549107B2 (en) 2023-01-10
SG10202106412RA (en) 2021-07-29
MY204487A (en) 2024-08-30
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