CO2018000991A2 - Tableta - Google Patents
TabletaInfo
- Publication number
- CO2018000991A2 CO2018000991A2 CONC2018/0000991A CO2018000991A CO2018000991A2 CO 2018000991 A2 CO2018000991 A2 CO 2018000991A2 CO 2018000991 A CO2018000991 A CO 2018000991A CO 2018000991 A2 CO2018000991 A2 CO 2018000991A2
- Authority
- CO
- Colombia
- Prior art keywords
- tablet
- outer layer
- active ingredients
- inner core
- potassium ion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
RESUMEN La presente invención proporciona una tableta en la cual la estabilidad de los ingredientes activos (un bloqueador de ácido competitivo con el ion de potasio y ácido acetilsalicílico) es alta y las actividades farmacológicas de los ingredientes activos se pueden ejercer de manera estable y rápida después de la administración de la tableta. La presente invención se refiere a una tableta con revestimiento entérico que tiene un núcleo interior y una capa exterior, en donde el núcleo interior contiene ácido acetilsalicílico y la capa exterior contiene un bloqueador de ácido competitivo con el ion de potasio que no está revestido entéricamente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015151336 | 2015-07-30 | ||
PCT/JP2016/072109 WO2017018473A1 (ja) | 2015-07-30 | 2016-07-28 | 錠剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2018000991A2 true CO2018000991A2 (es) | 2018-05-10 |
Family
ID=57884505
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2018/0000991A CO2018000991A2 (es) | 2015-07-30 | 2018-01-30 | Tableta |
Country Status (21)
Country | Link |
---|---|
US (1) | US10835541B2 (es) |
EP (1) | EP3329921B1 (es) |
JP (1) | JP6778680B2 (es) |
KR (1) | KR20180030412A (es) |
CN (1) | CN108135915B (es) |
BR (1) | BR112018001859B1 (es) |
CA (1) | CA2994073C (es) |
CL (1) | CL2018000246A1 (es) |
CO (1) | CO2018000991A2 (es) |
CR (1) | CR20180119A (es) |
EC (1) | ECSP18015616A (es) |
ES (1) | ES2977953T3 (es) |
HK (1) | HK1249857A1 (es) |
MX (1) | MX2018001209A (es) |
MY (1) | MY189306A (es) |
PE (1) | PE20180605A1 (es) |
PH (1) | PH12018500236A1 (es) |
SG (2) | SG11201800591TA (es) |
TW (1) | TWI710379B (es) |
UA (1) | UA124663C2 (es) |
WO (1) | WO2017018473A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11696893B2 (en) * | 2017-07-10 | 2023-07-11 | Takeda Pharmaceutical Company Limited | Preparation comprising vonoprazan |
CN110538153B (zh) * | 2019-09-26 | 2022-04-26 | 扬子江药业集团四川海蓉药业有限公司 | 一种高稳定性、快速释放的固体制剂及其制备方法 |
UY39094A (es) * | 2020-02-27 | 2021-07-30 | Hk Inno N Corp | Composición farmacéutica que comprende compuesto derivado de bencimidazol |
CA3203701A1 (en) * | 2020-12-30 | 2022-07-07 | Min Jung Kim | Pharmaceutical composition comprising tegoprazan and non-steroidal anti-inflammatory drugs |
WO2023106842A1 (ko) | 2021-12-08 | 2023-06-15 | (주) 팜젠사이언스 | 벤즈이미다졸 유도체 화합물 및 이의 용도 |
CN118236338B (zh) * | 2024-05-29 | 2024-09-17 | 寿光富康制药有限公司 | 一种富马酸伏诺拉生制剂的制备方法 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
GB9814215D0 (en) | 1998-07-01 | 1998-09-02 | Norton Healthcare Ltd | Anti-inflammatory pharmaceutical formulations |
US20020028240A1 (en) * | 2000-04-17 | 2002-03-07 | Toyohiro Sawada | Timed-release compression-coated solid composition for oral administration |
US6544556B1 (en) | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
PT1411900E (pt) | 2001-06-01 | 2010-10-11 | Pozen Inc | Composições farmacêuticas para a entrega coordenada de aines |
US8206741B2 (en) * | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
DE10317023A1 (de) | 2003-04-11 | 2004-11-11 | Altana Pharma Ag | Perorale Arzneimittelzubereitung für Protonenpumpenantagonisten |
TW200503783A (en) | 2003-04-11 | 2005-02-01 | Altana Pharma Ag | Oral pharmaceutical preparation for proton pump antagonists |
SA04250092B1 (ar) | 2003-05-14 | 2008-05-04 | التانا فاروا ايه جي | مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً |
CN101361738A (zh) | 2003-11-03 | 2009-02-11 | 阿斯利康(瑞典)有限公司 | 治疗隐匿性胃食管反流的咪唑并[1,2-a]吡啶衍生物 |
EP1718303A4 (en) | 2004-02-10 | 2010-09-01 | Santarus Inc | COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG |
US20050249799A1 (en) * | 2004-03-03 | 2005-11-10 | Spherics, Inc. | Polymeric drug delivery system for hydrophobic drugs |
AR057181A1 (es) | 2005-11-30 | 2007-11-21 | Astra Ab | Nueva forma de dosificacion de combinacion |
US7776873B2 (en) | 2005-12-01 | 2010-08-17 | Yuhan Corporation | Method for treating damage to gastric mucosa |
WO2007125397A2 (en) | 2006-04-27 | 2007-11-08 | Vecta, Ltd. | Compositions and methods for inhibiting gastric acidity using endoperoxide bridge-containing compounds |
US20090123390A1 (en) | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Compositions for the treatment of gastrointestinal inflammation |
CN102164581A (zh) | 2008-07-28 | 2011-08-24 | 武田药品工业株式会社 | 药物组合物 |
SI2318390T1 (sl) | 2008-08-27 | 2013-08-30 | Takeda Pharmaceutical Company Limited | Pirolne spojine |
US20100305163A1 (en) | 2009-05-20 | 2010-12-02 | Pramod Dattatray Yedurkar | Pharmaceutical formulations comprising nsaid and proton pump inhibitor drugs |
CA2765033C (en) | 2009-06-12 | 2020-07-14 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
MY162392A (en) | 2010-04-30 | 2017-06-15 | Takeda Pharmaceuticals Co | Enteric tablet |
ES2723029T3 (es) | 2010-04-30 | 2019-08-21 | Takeda Pharmaceuticals Co | Tableta entérica |
ES2561098T3 (es) | 2011-11-30 | 2016-02-24 | Takeda Pharmaceutical Company Limited | Comprimido recubierto en seco |
CN104519888A (zh) | 2011-12-28 | 2015-04-15 | 波曾公司 | 用于递送奥美拉唑和乙酰水杨酸的改良组合物和方法 |
CN105412038A (zh) | 2015-12-11 | 2016-03-23 | 北京阜康仁生物制药科技有限公司 | 一种包含沃诺拉赞和非甾体抗炎药的复方制剂 |
-
2016
- 2016-07-28 WO PCT/JP2016/072109 patent/WO2017018473A1/ja active Application Filing
- 2016-07-28 JP JP2017530918A patent/JP6778680B2/ja active Active
- 2016-07-28 CR CR20180119A patent/CR20180119A/es unknown
- 2016-07-28 SG SG11201800591TA patent/SG11201800591TA/en unknown
- 2016-07-28 TW TW105123872A patent/TWI710379B/zh active
- 2016-07-28 EP EP16830578.7A patent/EP3329921B1/en active Active
- 2016-07-28 CN CN201680057042.6A patent/CN108135915B/zh active Active
- 2016-07-28 ES ES16830578T patent/ES2977953T3/es active Active
- 2016-07-28 UA UAA201801698A patent/UA124663C2/uk unknown
- 2016-07-28 SG SG10201914087UA patent/SG10201914087UA/en unknown
- 2016-07-28 MX MX2018001209A patent/MX2018001209A/es unknown
- 2016-07-28 PE PE2018000136A patent/PE20180605A1/es unknown
- 2016-07-28 KR KR1020187005135A patent/KR20180030412A/ko not_active Application Discontinuation
- 2016-07-28 US US15/748,446 patent/US10835541B2/en active Active
- 2016-07-28 BR BR112018001859-7A patent/BR112018001859B1/pt active IP Right Grant
- 2016-07-28 MY MYPI2018700352A patent/MY189306A/en unknown
- 2016-07-28 CA CA2994073A patent/CA2994073C/en active Active
-
2018
- 2018-01-26 CL CL2018000246A patent/CL2018000246A1/es unknown
- 2018-01-29 PH PH12018500236A patent/PH12018500236A1/en unknown
- 2018-01-30 CO CONC2018/0000991A patent/CO2018000991A2/es unknown
- 2018-02-28 EC ECIEPI201815616A patent/ECSP18015616A/es unknown
- 2018-07-19 HK HK18109337.3A patent/HK1249857A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
UA124663C2 (uk) | 2021-10-27 |
SG10201914087UA (en) | 2020-03-30 |
WO2017018473A1 (ja) | 2017-02-02 |
JPWO2017018473A1 (ja) | 2018-05-17 |
CL2018000246A1 (es) | 2018-06-29 |
JP6778680B2 (ja) | 2020-11-04 |
EP3329921A1 (en) | 2018-06-06 |
ECSP18015616A (es) | 2018-07-31 |
CR20180119A (es) | 2018-03-21 |
EP3329921A4 (en) | 2019-03-27 |
EP3329921B1 (en) | 2024-03-27 |
US10835541B2 (en) | 2020-11-17 |
BR112018001859B1 (pt) | 2023-05-02 |
MX2018001209A (es) | 2018-07-06 |
CN108135915A (zh) | 2018-06-08 |
TWI710379B (zh) | 2020-11-21 |
CA2994073C (en) | 2023-09-05 |
SG11201800591TA (en) | 2018-02-27 |
HK1249857A1 (zh) | 2018-11-16 |
PH12018500236A1 (en) | 2018-08-13 |
ES2977953T3 (es) | 2024-09-03 |
MY189306A (en) | 2022-02-03 |
KR20180030412A (ko) | 2018-03-22 |
CN108135915B (zh) | 2021-06-25 |
BR112018001859A2 (pt) | 2018-11-27 |
US20180214460A1 (en) | 2018-08-02 |
CA2994073A1 (en) | 2017-02-02 |
TW201714608A (zh) | 2017-05-01 |
PE20180605A1 (es) | 2018-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CO2018000991A2 (es) | Tableta | |
CR20140486A (es) | Formulacion de farmaco de liberacion retardada | |
CR20160192A (es) | Formulación de farmaco de liberación retardada | |
CL2017003459A1 (es) | Derivados de sulfamoilarilamida ciclados y su uso como medicamentos para el tratamiento de la hepatitis b. | |
CL2016000143A1 (es) | Comprimido farmacéutico que comprende ácido acetilsalicílico y clopidogrel | |
EA201490366A1 (ru) | Модульная центральная конструкция для совместного запуска космических летательных аппаратов | |
AR089032A1 (es) | Comprimido recubierto seco | |
TWD173639S (zh) | 針盤 | |
UY36703A (es) | Composiciones y métodos para la administración de un polinucleótido en una planta | |
CL2015002148A1 (es) | Formulaciones farmacéuticas resistentes a la manipulación indebida | |
AR107029A1 (es) | Conexión roscada que incluye un reborde intermedio | |
CL2018001298A1 (es) | Un proceso para preparar una formulación en polvo seco que comprende un anticolinérgico, un corticosteroide y un beta-adrenérgico | |
CL2017001615A1 (es) | Pirazolpiridinaminas como inhibidores de mknk1 y mknk2. | |
BR112017008802A2 (pt) | precursor de recipiente, processo, recipiente fechado e uso do precursor de recipiente | |
CL2015001446A1 (es) | Procedimiento de preparación de albumina humana con nivel de oxigeno disuelto reducido. | |
AR094371A1 (es) | Punzón para fabricación de tubos en caliente | |
CO2018002428A2 (es) | Amida seleccionada de ácido gamma-hidroxiburico y usos de la misma en el tratamiento de abuso de alcohol | |
ITUA20162125A1 (it) | Turbomacchina radiale con compensazione della spinta assiale | |
CO2018002590A2 (es) | Sistemas y métodos para utilizar estructuras biomiméticas que proporcionan comunicación en tejidos vivientes | |
AR101728A1 (es) | Formulación de liberación plurimodal de doxilamina y piridoxina y/o metabolitos o sales de las mismas | |
PE20181374A1 (es) | Formulacion de combinacion farmaceutica | |
CL2016000529A1 (es) | Capa de recubrimiento aislante entre un núcleo que comprende al fármaco y un recubrimiento exterior compuesto por una capa interna y una capa externa, su uso, una formulación de fármaco que contiene a dicha capa aislante, un método para producir a la formulación. | |
张静雅 | Translating Technical Texts in Light of Economy Principle | |
AR104877A1 (es) | Composiciones y métodos para la administración de un polinucleótido en una planta | |
BR112016030731A2 (pt) | Preparação de compósito, e, método de preparação de uma preparação de compósito |